| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-136 |
Sentence |
denotes |
The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. |
| T2 |
137-147 |
Sentence |
denotes |
OBJECTIVE: |
| T3 |
148-343 |
Sentence |
denotes |
This study was designed to evaluate the effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes among subjects with gestational diabetes (GDM). |
| T4 |
344-352 |
Sentence |
denotes |
METHODS: |
| T5 |
353-495 |
Sentence |
denotes |
This randomized, double-blind, placebo-controlled clinical trial was done among 60 subjects with GDM who were not on oral hypoglycemic agents. |
| T6 |
496-716 |
Sentence |
denotes |
Patients were randomly allocated to intake either probiotic capsule containing Lactobacillus acidophilus, Lactobacillus casei and Bifidobacterium bifidum (2 × 10(9) CFU/g each) (n = 30) or placebo (n = 30) for six weeks. |
| T7 |
717-725 |
Sentence |
denotes |
RESULTS: |
| T8 |
726-1263 |
Sentence |
denotes |
Compared with the placebo, probiotic supplementation resulted in significant decreases in fasting plasma glucose (FPG) (-5.3 ± 6.7 vs. +0.03 ± 9.0 mg/dL, p = .01), serum high-sensitivity C-reactive protein (hs-CRP) (-2.2 ± 2.7 vs. +0.5 ± 2.4 μg/mL, p < .001), plasma malondialdehyde (MDA) concentrations (-0.1 ± 0.8 vs. +0.5 ± 1.5 μmol/L, p = .03) and MDA/TAC ratio (-0.0003 ± 0.0008 vs. +0.0009 ± 0.002, p = .004), and a significant increase in total antioxidant capacity (TAC) levels (+65.4 ± 103.3 vs. -37.2 ± 143.7 mmol/L, p = .002). |
| T9 |
1264-1324 |
Sentence |
denotes |
Probiotic supplementation did not affect pregnancy outcomes. |
| T10 |
1325-1337 |
Sentence |
denotes |
CONCLUSIONS: |
| T11 |
1338-1535 |
Sentence |
denotes |
Overall, probiotic supplementation among women with GDM for six weeks had beneficial effects on FPG, serum hs-CRP, plasma TAC, MDA and oxidative stress index, but did not affect pregnancy outcomes. |
| T1 |
0-136 |
Sentence |
denotes |
The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. |
| T2 |
137-147 |
Sentence |
denotes |
OBJECTIVE: |
| T3 |
148-343 |
Sentence |
denotes |
This study was designed to evaluate the effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes among subjects with gestational diabetes (GDM). |
| T4 |
344-352 |
Sentence |
denotes |
METHODS: |
| T5 |
353-495 |
Sentence |
denotes |
This randomized, double-blind, placebo-controlled clinical trial was done among 60 subjects with GDM who were not on oral hypoglycemic agents. |
| T6 |
496-716 |
Sentence |
denotes |
Patients were randomly allocated to intake either probiotic capsule containing Lactobacillus acidophilus, Lactobacillus casei and Bifidobacterium bifidum (2 × 10(9) CFU/g each) (n = 30) or placebo (n = 30) for six weeks. |
| T7 |
717-725 |
Sentence |
denotes |
RESULTS: |
| T8 |
726-1263 |
Sentence |
denotes |
Compared with the placebo, probiotic supplementation resulted in significant decreases in fasting plasma glucose (FPG) (-5.3 ± 6.7 vs. +0.03 ± 9.0 mg/dL, p = .01), serum high-sensitivity C-reactive protein (hs-CRP) (-2.2 ± 2.7 vs. +0.5 ± 2.4 μg/mL, p < .001), plasma malondialdehyde (MDA) concentrations (-0.1 ± 0.8 vs. +0.5 ± 1.5 μmol/L, p = .03) and MDA/TAC ratio (-0.0003 ± 0.0008 vs. +0.0009 ± 0.002, p = .004), and a significant increase in total antioxidant capacity (TAC) levels (+65.4 ± 103.3 vs. -37.2 ± 143.7 mmol/L, p = .002). |
| T9 |
1264-1324 |
Sentence |
denotes |
Probiotic supplementation did not affect pregnancy outcomes. |
| T10 |
1325-1337 |
Sentence |
denotes |
CONCLUSIONS: |
| T11 |
1338-1535 |
Sentence |
denotes |
Overall, probiotic supplementation among women with GDM for six weeks had beneficial effects on FPG, serum hs-CRP, plasma TAC, MDA and oxidative stress index, but did not affect pregnancy outcomes. |
