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GoldHamster

Id Subject Object Predicate Lexical cue
T2 0-13 CHEBI:80307 denotes Kisspeptin-10
T3 0-13 C106628 denotes Kisspeptin-10
T4 0-13 C106628 denotes Kisspeptin-10
T5 43-47 PR:P07490 denotes GnRH
T6 43-47 PR:000008127 denotes GnRH
T7 43-47 PR:P13562 denotes GnRH
T8 43-47 P27429 denotes GnRH
T11 43-47 PR:P01148 denotes GnRH
T9 43-47 D007987 denotes GnRH
T10 43-47 D007987 denotes GnRH
T12 88-101 9544 denotes rhesus monkey
T13 88-101 D008253 denotes rhesus monkey
T15 143-147 C564835 denotes ESCs
T16 239-248 CL:0000034 denotes stem cell
T17 239-264 GO:0048863 denotes stem cell differentiation
T19 278-287 GO:0023052 denotes signaling
T20 349-359 CHEBI:80304 denotes kisspeptin
T22 360-367 PR:000018264 denotes peptide
T24 360-367 PR:000018263 denotes peptide
T21 360-367 SO:0001064 denotes peptide
T23 360-367 CHEBI:16670 denotes peptide
T25 427-441 9544 denotes rhesus macaque
T26 427-441 D008253 denotes rhesus macaque
T28 450-453 PR:P16525 denotes tau
T29 450-453 PR:000024142 denotes tau
T30 450-453 PR:P10636 denotes tau
T31 450-453 PR:000010173 denotes tau
T32 450-453 PR:P19332 denotes tau
T34 450-453 PR:P10637 denotes tau
T33 450-453 CHEBI:36355 denotes tau
T35 450-465 CVCL_XV41 denotes tau GFP-Lyon ES
T38 482-492 CHEBI:80304 denotes kisspeptin
T39 682-700 CL:0000047 denotes neuronal stem cell
T41 702-705 617394 denotes NSC
T42 702-705 CL:0000047 denotes NSC
T43 774-781 D006728 denotes Hormone
T44 774-781 D006728 denotes Hormone
T45 774-781 CHEBI:24621 denotes Hormone
T46 783-787 PR:P07490 denotes GnRH
T47 783-787 PR:000008127 denotes GnRH
T48 783-787 PR:P13562 denotes GnRH
T49 783-787 P27429 denotes GnRH
T52 783-787 PR:P01148 denotes GnRH
T50 783-787 D007987 denotes GnRH
T51 783-787 D007987 denotes GnRH
T53 906-916 CHEBI:80304 denotes kisspeptin
T54 917-926 GO:0023052 denotes signaling
T55 928-932 PR:P07490 denotes GnRH
T56 928-932 PR:000008127 denotes GnRH
T57 928-932 PR:P13562 denotes GnRH
T58 928-932 P27429 denotes GnRH
T61 928-932 PR:P01148 denotes GnRH
T59 928-932 D007987 denotes GnRH
T60 928-932 D007987 denotes GnRH
T62 972-992 D009358 denotes congenital disorders
T63 972-992 D009358 denotes congenital disorders
T64 998-1038 C562785 denotes idiopathic hypogonadotropic hypogonadism
T65 998-1038 C562785 denotes idiopathic hypogonadotropic hypogonadism
T70 1040-1043 PR:Q98938 denotes IHH
T71 1040-1043 P79711 denotes IHH
T72 1040-1043 P97812 denotes IHH
T73 1040-1043 P79866 denotes IHH
T74 1040-1043 Q98938 denotes IHH
T75 1040-1043 P79719 denotes IHH
T78 1040-1043 O13215 denotes IHH
T79 1040-1043 P79693 denotes IHH
T80 1040-1043 O13240 denotes IHH
T81 1040-1043 P79871 denotes IHH
T82 1040-1043 P79860 denotes IHH
T83 1040-1043 Q91612 denotes IHH
T84 1040-1043 PR:Q98862 denotes IHH
T85 1040-1043 PR:000008974 denotes IHH
T86 1040-1043 Q14623 denotes IHH
T87 1040-1043 PR:P97812 denotes IHH
T88 1040-1043 PR:Q14623 denotes IHH
T90 1040-1043 P79852 denotes IHH
T91 1040-1043 O13220 denotes IHH
T92 1040-1043 O13243 denotes IHH
T76 1040-1043 CVCL_SA11 denotes IHH
T89 1040-1043 CVCL_8278 denotes IHH
T77 1040-1043 C562785 denotes IHH
T93 1100-1109 GO:0009058 denotes formation
T94 1129-1133 PR:P07490 denotes GnRH
T95 1129-1133 PR:000008127 denotes GnRH
T96 1129-1133 PR:P13562 denotes GnRH
T97 1129-1133 P27429 denotes GnRH
T100 1129-1133 PR:P01148 denotes GnRH
T98 1129-1133 D007987 denotes GnRH
T99 1129-1133 D007987 denotes GnRH
T102 1206-1209 CL:0000047 denotes NSC
T101 1206-1209 617394 denotes NSC
T104 1242-1245 CL:0000047 denotes NSC
T103 1242-1245 617394 denotes NSC

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 121-331 DRI_Background denotes Embryonic stem cells (ESCs) have enormous potential as novel cell-based therapies, but their effectiveness depends on stem cell differentiation and specific signaling regulators, which remain poorly understood.
T2 332-527 DRI_Approach denotes In this study, a kisspeptin peptide (KP-10) was used at different dosages to determine whether rhesus macaque-derived tau GFP-Lyon ES cells underwent kisspeptin-specific neuronal differentiation.
T3 528-719 DRI_Outcome denotes It was found that KP-10 exhibited an anti-proliferative effect on the cells and led to morphological changes and cellular differentiation consistent with neuronal stem cell (NSC) development.
T4 720-849 DRI_Approach denotes The cells differentiated into Gonadotrophin Releasing Hormone (GnRH) neuronal-like cell types in response to the KP-10 treatment.
T5 850-1045 DRI_Background denotes There has been a previously observed connection between kisspeptin signaling, GnRH neurons and their dysfunction found in congenital disorders like idiopathic hypogonadotropic hypogonadism (IHH).
T6 1046-1128 DRI_Background denotes Although therapeutics are a still a far-off goal, the formation and development of
T7 1157-1303 DRI_Background denotes cells following the application of KP-10 to Lyon NSC cells opens the door for future NSC-based therapies to treat specific reproductive disorders.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 347-348 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T2 450-465 CVCL_XV41|Embryonic_stem_cell|Macaca mulatta denotes tau GFP-Lyon ES
T3 454-465 CVCL_XV59|Embryonic_stem_cell|Macaca mulatta denotes GFP-Lyon ES
T4 562-564 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T5 562-564 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T6 629-636 CVCL_0238|Cancer_cell_line|Homo sapiens denotes changes
T7 856-859 CVCL_6758|Undefined_cell_line_type|Cricetulus griseus denotes has
T8 856-859 CVCL_E689|Transformed_cell_line|Homo sapiens denotes has
T9 865-866 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T10 1040-1043 CVCL_8278|Transformed_cell_line|Homo sapiens denotes IHH
T11 1040-1043 CVCL_SA11|Transformed_cell_line|Homo sapiens denotes IHH
T12 1072-1073 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T13 1080-1081 CVCL_6479|Finite_cell_line|Mus musculus denotes a