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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-107 Sentence denotes Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.
TextSentencer_T2 108-251 Sentence denotes apoB DNA, RNA, and protein from two patients with homozygous hypobetalipoproteinemia (HBL) were evaluated and compared with normal individuals.
TextSentencer_T3 252-383 Sentence denotes Southern blot analysis with 10 different cDNA probes revealed a normal gene without major insertions, deletions, or rearrangements.
TextSentencer_T4 384-536 Sentence denotes Northern and slot blot analyses of total liver mRNA from HBL patients documented a normal size apoB mRNA that was present in greatly reduced quantities.
TextSentencer_T5 537-708 Sentence denotes ApoB protein was detected within HBL hepatocytes utilizing immunohistochemical techniques; however, it was markedly reduced in quantity when compared with control samples.
TextSentencer_T6 709-785 Sentence denotes No apoB was detectable in the plasma of HBL individuals with an ELISA assay.
TextSentencer_T7 786-951 Sentence denotes These data are most consistent with a mutation in the coding portion of the apoB gene in HBL patients, leading to an abnormal apoB protein and apoB mRNA instability.
TextSentencer_T8 952-1153 Sentence denotes These results are distinct from those previously noted in abetalipoproteinemia, which was characterized by an elevated level of hepatic apoB mRNA and accumulation of intracellular hepatic apoB protein.
T1 0-107 Sentence denotes Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.
T2 108-251 Sentence denotes apoB DNA, RNA, and protein from two patients with homozygous hypobetalipoproteinemia (HBL) were evaluated and compared with normal individuals.
T3 252-383 Sentence denotes Southern blot analysis with 10 different cDNA probes revealed a normal gene without major insertions, deletions, or rearrangements.
T4 384-536 Sentence denotes Northern and slot blot analyses of total liver mRNA from HBL patients documented a normal size apoB mRNA that was present in greatly reduced quantities.
T5 537-708 Sentence denotes ApoB protein was detected within HBL hepatocytes utilizing immunohistochemical techniques; however, it was markedly reduced in quantity when compared with control samples.
T6 709-785 Sentence denotes No apoB was detectable in the plasma of HBL individuals with an ELISA assay.
T7 786-951 Sentence denotes These data are most consistent with a mutation in the coding portion of the apoB gene in HBL patients, leading to an abnormal apoB protein and apoB mRNA instability.
T8 952-1153 Sentence denotes These results are distinct from those previously noted in abetalipoproteinemia, which was characterized by an elevated level of hepatic apoB mRNA and accumulation of intracellular hepatic apoB protein.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 537-541 gene:338 denotes ApoB
T1 570-573 disease:C0020597 denotes HBL
R1 T0 T1 associated_with ApoB,HBL

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 169-192 HP_0003563 denotes hypobetalipoproteinemia
T2 1010-1030 HP_0008181 denotes abetalipoproteinemia

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
2828430-6#76#80#gene338 862-866 gene338 denotes apoB
2828430-6#89#92#diseaseC0206624 875-878 diseaseC0206624 denotes HBL
76#80#gene33889#92#diseaseC0206624 2828430-6#76#80#gene338 2828430-6#89#92#diseaseC0206624 associated_with apoB,HBL

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 425-430 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver

PubCasesHPO

Id Subject Object Predicate Lexical cue
TI1 11-34 HP:0003563 denotes hypobetalipoproteinemia
AB1 169-192 HP:0003563 denotes hypobetalipoproteinemia
AB2 1010-1030 HP:0008181 denotes abetalipoproteinemia

PubCasesORDO

Id Subject Object Predicate Lexical cue
AB1 1010-1030 ORDO:14 denotes abetalipoproteinemia

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 425-430 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver

NCBIDiseaseCorpus

Id Subject Object Predicate Lexical cue
T1 0-34 SpecificDisease:D006995 denotes Homozygous hypobetalipoproteinemia
T2 60-83 SpecificDisease:D000012 denotes abetalipoproproteinemia
T3 158-192 SpecificDisease:D006995 denotes homozygous hypobetalipoproteinemia
T4 194-197 SpecificDisease:D006995 denotes HBL
T5 441-444 Modifier:D006995 denotes HBL
T6 570-573 Modifier:D006995 denotes HBL
T7 749-752 Modifier:D006995 denotes HBL
T8 875-878 Modifier:D006995 denotes HBL
T9 1010-1030 SpecificDisease:D000012 denotes abetalipoproteinemia

NCBI-Disease-Train

Id Subject Object Predicate Lexical cue database_id
T135 0-34 SpecificDisease denotes Homozygous hypobetalipoproteinemia D006995
T136 60-83 SpecificDisease denotes abetalipoproproteinemia D000012
T137 158-192 SpecificDisease denotes homozygous hypobetalipoproteinemia D006995
T138 194-197 SpecificDisease denotes HBL D006995
T139 441-444 Modifier denotes HBL D006995
T140 570-573 Modifier denotes HBL D006995
T141 749-752 Modifier denotes HBL D006995
T142 875-878 Modifier denotes HBL D006995
T143 1010-1030 SpecificDisease denotes abetalipoproteinemia D000012

NCBI-Disease-Corpus-All

Id Subject Object Predicate Lexical cue database_id
T135 0-34 SpecificDisease denotes Homozygous hypobetalipoproteinemia D006995
T136 60-83 SpecificDisease denotes abetalipoproproteinemia D000012
T137 158-192 SpecificDisease denotes homozygous hypobetalipoproteinemia D006995
T138 194-197 SpecificDisease denotes HBL D006995
T139 441-444 Modifier denotes HBL D006995
T140 570-573 Modifier denotes HBL D006995
T141 749-752 Modifier denotes HBL D006995
T142 875-878 Modifier denotes HBL D006995
T143 1010-1030 SpecificDisease denotes abetalipoproteinemia D000012

NCBI-Disease-Corpus-2stage-All

Id Subject Object Predicate Lexical cue
T1 11-34 SpecificDisease denotes hypobetalipoproteinemia
T2 60-83 SpecificDisease denotes abetalipoproproteinemia
T3 169-192 SpecificDisease denotes hypobetalipoproteinemia
T4 441-444 Modifier denotes HBL
T5 570-573 Modifier denotes HBL
T6 749-752 Modifier denotes HBL
T7 875-878 Modifier denotes HBL
T8 1010-1030 SpecificDisease denotes abetalipoproteinemia

NCBI-Disease-Corpus-rezarta-All

Id Subject Object Predicate Lexical cue
T1 11-34 SpecificDisease denotes hypobetalipoproteinemia
T2 60-83 SpecificDisease denotes abetalipoproproteinemia
T3 169-192 SpecificDisease denotes hypobetalipoproteinemia
T4 1010-1030 SpecificDisease denotes abetalipoproteinemia

NCBI-Disease-Corpus-4oGuideline-All

Id Subject Object Predicate Lexical cue
T1 0-34 SpecificDisease denotes Homozygous hypobetalipoproteinemia
T2 60-83 SpecificDisease denotes abetalipoproproteinemia
T3 158-192 SpecificDisease denotes homozygous hypobetalipoproteinemia
T4 441-444 SpecificDisease denotes HBL
T5 570-573 SpecificDisease denotes HBL
T6 749-752 SpecificDisease denotes HBL
T7 875-878 SpecificDisease denotes HBL
T8 1010-1030 SpecificDisease denotes abetalipoproteinemia

NCBI-Disease-Corpus-Simple-All

Id Subject Object Predicate Lexical cue
T1 0-34 SpecificDisease denotes Homozygous hypobetalipoproteinemia
T2 60-83 SpecificDisease denotes abetalipoproproteinemia
T3 158-192 SpecificDisease denotes homozygous hypobetalipoproteinemia
T4 441-444 SpecificDisease denotes HBL
T5 570-573 SpecificDisease denotes HBL
T6 749-752 SpecificDisease denotes HBL
T7 875-878 SpecificDisease denotes HBL
T8 1010-1030 SpecificDisease denotes abetalipoproteinemia