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PubMed:28248002 JSONTXT

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GoldHamster

Id Subject Object Predicate Lexical cue
T3 0-10 SO:0001237 denotes Amino Acid
T2 0-10 CHEBI:33704 denotes Amino Acid
T4 0-10 CHEBI:33709 denotes Amino Acid
T6 11-27 CHEBI:53511 denotes Block Copolymers
T9 39-52 CHEBI:33281 denotes Antimicrobial
T10 121-126 SO:0000419 denotes chain
T11 128-137 32630 denotes synthetic
T14 165-175 SO:0001237 denotes amino acid
T13 165-175 CHEBI:33704 denotes amino acid
T15 165-175 CHEBI:33709 denotes amino acid
T17 176-191 CHEBI:53511 denotes block copolymer
T20 218-221 CVCL_E777 denotes min
T21 253-257 CVCL_3996 denotes K100
T23 258-261 CVCL_M973 denotes L40
T25 258-261 CVCL_XK71 denotes L40
T22 258-261 C049389 denotes L40
T24 258-261 C049389 denotes L40
T26 262-278 CHEBI:53511 denotes block copolymers
T29 280-284 CL:0000775 denotes poly
T30 280-284 CL:0000096 denotes poly
T31 280-293 CHEBI:61490 denotes poly(l-lysine
T32 280-293 CHEBI:53412 denotes poly(l-lysine
T35 285-293 6536 denotes l-lysine
T40 287-293 SO:0001450 denotes lysine
T46 294-307 CHEBI:17883 denotes hydrochloride
T47 294-307 CHEBI:36807 denotes hydrochloride
T48 315-319 CL:0000775 denotes poly
T49 315-319 CL:0000096 denotes poly
T50 315-329 C027819 denotes poly(l-leucine
T51 315-329 C027819 denotes poly(l-leucine
T55 320-329 6308 denotes l-leucine
T60 322-329 SO:0001437 denotes leucine
T64 366-371 PR:Q8W4I9 denotes mL(-1
T65 366-371 Q9GZU1 denotes mL(-1
T66 366-371 Q9NTI2 denotes mL(-1
T69 366-371 PR:000029291 denotes mL(-1
T67 366-371 CVCL_H525 denotes mL(-1
T68 366-371 CVCL_0436 denotes mL(-1
T70 444-466 D006090 denotes Gram-negative bacteria
T72 479-484 214355 denotes yeast
T71 479-484 D015003 denotes yeast
T73 516-523 D013180 denotes strains
T74 516-523 D013180 denotes strains
T75 572-576 CVCL_3996 denotes K100
T77 577-580 CVCL_M973 denotes L40
T79 577-580 CVCL_XK71 denotes L40
T76 577-580 C049389 denotes L40
T78 577-580 C049389 denotes L40
T80 581-591 CHEBI:60804 denotes copolymers
T81 581-591 CHEBI:53310 denotes copolymers
T82 635-644 D020100 denotes hydrogels
T83 635-644 D020100 denotes hydrogels
T86 708-712 CVCL_3996 denotes K100
T88 713-716 CVCL_M973 denotes L40
T90 713-716 CVCL_XK71 denotes L40
T87 713-716 C049389 denotes L40
T89 713-716 C049389 denotes L40
T91 835-841 UBERON:0000479 denotes tissue
T92 901-905 UBERON:0002199 denotes skin
T93 901-905 UBERON:0000014 denotes skin
T94 901-905 UBERON:0001003 denotes skin
T95 901-905 UBERON:0002097 denotes skin
T96 941-947 D012377 denotes rodent
T97 967-979 D005547 denotes foreign body
T98 967-979 D005547 denotes foreign body
T101 1006-1016 SO:0001237 denotes amino acid
T100 1006-1016 CHEBI:33704 denotes amino acid
T102 1006-1016 CHEBI:33709 denotes amino acid
T104 1017-1027 CHEBI:60804 denotes copolymers
T105 1017-1027 CHEBI:53310 denotes copolymers
T106 1049-1053 CVCL_3996 denotes K100
T107 1054-1057 C049389 denotes L40
T109 1054-1057 C049389 denotes L40
T108 1054-1057 CVCL_M973 denotes L40
T110 1054-1057 CVCL_XK71 denotes L40
T111 1085-1098 CHEBI:33281 denotes antimicrobial
T112 1138-1148 D001704 denotes biopolymer
T113 1138-1148 CHEBI:33694 denotes biopolymer
T114 1185-1201 D014946 denotes wound infections
T115 1185-1201 D014946 denotes wound infections

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 86-205 DRI_Background denotes Antimicrobial properties of a long-chain, synthetic, cationic, and hydrophobic amino acid block copolymer are reported.
T2 206-524 DRI_Outcome denotes In 5 and 60 min time-kill assays, solutions of K100 L40 block copolymers (poly(l-lysine·hydrochloride)100 -b-poly(l-leucine)40 ) at concentrations of 10-100 µg mL(-1) show multi-log reductions in colony forming units of Gram-positive and Gram-negative bacteria, as well as yeast, including multidrug-resistant strains.
T3 525-701 DRI_Background denotes Driven by association of hydrophobic segments, K100 L40 copolymers form viscous solutions and self-supporting hydrogels in water at concentrations of 1 and 2 wt%, respectively.
T4 702-980 DRI_Challenge denotes These K100 L40 preparations provide an effective barrier to microbial contamination of wounds, as measured by multi-log decreases of tissue-associated bacteria with deliberate inoculation of porcine skin explants, porcine open wounds, and rodent closed wounds with foreign body.
T5 981-1202 DRI_Background denotes Based on these findings, amino acid copolymers with the features of K100 L40 can combine potent, direct antimicrobial activity and barrier properties in one biopolymer for a new approach to prevention of wound infections.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 53-61 CVCL_C410|Hybridoma|Mus musculus denotes Activity
T2 114-115 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T3 215-217 CVCL_C917|Induced_pluripotent_stem_cell|Homo sapiens denotes 60
T4 218-221 CVCL_E777|Transformed_cell_line|Homo sapiens denotes min
T5 222-226 CVCL_0047|Telomerase_immortalized_cell_line|Homo sapiens denotes time
T6 253-257 CVCL_3996|Cancer_cell_line|Homo sapiens denotes K100
T7 258-261 CVCL_M973|Transformed_cell_line|Homo sapiens denotes L40
T8 258-261 CVCL_XK71|Hybridoma|Mus musculus denotes L40
T9 313-314 CVCL_6480|Finite_cell_line|Mus musculus denotes b
T10 330-332 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T11 366-372 CVCL_0436|Cancer_cell_line|Homo sapiens denotes mL(-1)
T12 366-372 CVCL_H525|Cancer_cell_line|Homo sapiens denotes mL(-1)
T13 366-368 CVCL_F566|Transformed_cell_line|Homo sapiens denotes mL
T14 366-368 CVCL_W799|Cancer_cell_line|Homo sapiens denotes mL
T15 572-576 CVCL_3996|Cancer_cell_line|Homo sapiens denotes K100
T16 577-580 CVCL_M973|Transformed_cell_line|Homo sapiens denotes L40
T17 577-580 CVCL_XK71|Hybridoma|Mus musculus denotes L40
T18 677-682 CVCL_B527|Embryonic_stem_cell|Homo sapiens denotes and 2
T19 683-685 CVCL_6D82|Cancer_cell_line|Homo sapiens denotes wt
T20 683-685 CVCL_Z880|Spontaneously_immortalized_cell_line|Drosophila melanogaster denotes wt
T21 683-685 CVCL_Z881|Spontaneously_immortalized_cell_line|Drosophila melanogaster denotes wt
T22 683-685 CVCL_Z882|Spontaneously_immortalized_cell_line|Drosophila melanogaster denotes wt
T23 708-712 CVCL_3996|Cancer_cell_line|Homo sapiens denotes K100
T24 713-716 CVCL_M973|Transformed_cell_line|Homo sapiens denotes L40
T25 713-716 CVCL_XK71|Hybridoma|Mus musculus denotes L40
T26 738-740 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T27 738-740 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T28 1049-1053 CVCL_3996|Cancer_cell_line|Homo sapiens denotes K100
T29 1054-1057 CVCL_M973|Transformed_cell_line|Homo sapiens denotes L40
T30 1054-1057 CVCL_XK71|Hybridoma|Mus musculus denotes L40
T31 1099-1107 CVCL_C410|Hybridoma|Mus musculus denotes activity
T32 1134-1137 CVCL_Z424|Spontaneously_immortalized_cell_line|Ostrinia nubilalis denotes one
T33 1153-1154 CVCL_6479|Finite_cell_line|Mus musculus denotes a