
PubMed:28101574
Annnotations
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-67 | Sentence | denotes | NEK2 serves as a prognostic biomarker for hepatocellular carcinoma. |
T2 | 68-251 | Sentence | denotes | Never in mitosis gene A (NIMA)-related kinase 2 (NEK2) is a microtubule-associated protein that regulates spindle assembly in human cells and is overexpressed in various malignancies. |
T3 | 252-333 | Sentence | denotes | However, the role of NEK2 in hepatocellular carcinoma (HCC) remains undetermined. |
T4 | 334-453 | Sentence | denotes | We performed RNA-seq of the HCC cell line SMMC-7721 and the normal liver cell line HL-7702 using the Ion Proton System. |
T5 | 454-626 | Sentence | denotes | NEK2 expression was detected using quantitative reverse transcription polymerase chain reaction in two cell lines and 5 matched HCC and adjacent non-tumorous liver tissues. |
T6 | 627-830 | Sentence | denotes | The correlation between survival and NEK2 expression was analyzed in 359 patients with HCC using RNASeqV2 data available from The Cancer Genome Atlas (TCGA) website (https://tcga-data.nci.nih.gov/tcga/). |
T7 | 831-982 | Sentence | denotes | The expression of NEK2, phospho-AKT and MMP-2 was evaluated by immunohistochemistry in 63 cases of HCC and matched adjacent non-tumorous liver tissues. |
T8 | 983-1162 | Sentence | denotes | Relationships between protein expression and clinicopathological parameters were assessed, and the correlations between NEK2 with phospho-AKT and MMP-2 expressions were evaluated. |
T9 | 1163-1327 | Sentence | denotes | A total of 610 differentially expressed genes (DEGs) were revealed in the transcriptome comparison, 297 of which were upregulated and 313 were downregulated in HCC. |
T10 | 1328-1480 | Sentence | denotes | NEK2, as the most obviously different DEG in cells and tissues from the RNA-seq data, was listed as an HCC candidate biomarker for further verification. |
T11 | 1481-1628 | Sentence | denotes | NEK2 was overexpressed in HCC cells and tissues (P=0.002, P=0.013) and HCC patients with a high expression of NEK2 had a poor prognosis (P=0.0145). |
T12 | 1629-1813 | Sentence | denotes | Clinical analysis indicated that the overexpression of NEK2 in HCC was significantly correlated with diolame complete (P<0.001), tumor nodule number (P=0.012) and recurrence (P=0.004). |
T13 | 1814-1937 | Sentence | denotes | NEK2 expression was positively correlated with the expression of phospho-AKT (r=0.883, P<0.01) and MMP-2 (r=0.781, P<0.01). |
T14 | 1938-2106 | Sentence | denotes | Overexpression of NEK2 was associated with clinicopathological characteristics and poor patient outcomes, suggesting that NEK2 serves as a prognostic biomarker for HCC. |
T15 | 2107-2277 | Sentence | denotes | Alteration of NEK2 protein levels may contribute to invasion and metastasis of HCC, which may occur through activation of AKT signaling and promotion of MMP-2 expression. |
LitCoin-entities-OrganismTaxon-PD
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 85-91 | OrganismTaxon | denotes | gene A | NCBItxid:695940|NCBItxid:137249 |
T3 | 194-199 | OrganismTaxon | denotes | human | NCBItxid:9606 |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
12133 | 0-4 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12134 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | MESH:D006528 |
12135 | 68-115 | GeneOrGeneProduct | denotes | Never in mitosis gene A (NIMA)-related kinase 2 | NCBIGene:4751 |
12136 | 117-121 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12137 | 128-158 | GeneOrGeneProduct | denotes | microtubule-associated protein | NCBIGene:4130 |
12138 | 194-199 | OrganismTaxon | denotes | human | NCBITaxon:9606 |
12139 | 238-250 | DiseaseOrPhenotypicFeature | denotes | malignancies | MESH:D009369 |
12140 | 273-277 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12141 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | MESH:D006528 |
12142 | 307-310 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12143 | 362-365 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12144 | 376-385 | CellLine | denotes | SMMC-7721 | NCBITaxon:9606 |
12145 | 417-424 | CellLine | denotes | HL-7702 | NCBITaxon:9606 |
12146 | 454-458 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12147 | 582-585 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12148 | 664-668 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12149 | 700-708 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
12150 | 714-717 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12151 | 757-763 | DiseaseOrPhenotypicFeature | denotes | Cancer | MESH:D009369 |
12152 | 849-853 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12153 | 863-866 | GeneOrGeneProduct | denotes | AKT | NCBIGene:207 |
12154 | 871-876 | GeneOrGeneProduct | denotes | MMP-2 | NCBIGene:4130 |
12155 | 930-933 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12156 | 1103-1107 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12157 | 1121-1124 | GeneOrGeneProduct | denotes | AKT | NCBIGene:207 |
12158 | 1129-1134 | GeneOrGeneProduct | denotes | MMP-2 | NCBIGene:4130 |
12159 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12160 | 1328-1332 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12161 | 1431-1434 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12162 | 1481-1485 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12163 | 1507-1510 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12164 | 1552-1555 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12165 | 1556-1564 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
12166 | 1591-1595 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12167 | 1684-1688 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12168 | 1692-1695 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12169 | 1758-1763 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
12170 | 1814-1818 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12171 | 1887-1890 | GeneOrGeneProduct | denotes | AKT | NCBIGene:207 |
12172 | 1913-1918 | GeneOrGeneProduct | denotes | MMP-2 | NCBIGene:4130 |
12173 | 1956-1960 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12174 | 2026-2033 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
12175 | 2060-2064 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12176 | 2102-2105 | DiseaseOrPhenotypicFeature | denotes | HCC | MESH:D006528 |
12177 | 2121-2125 | GeneOrGeneProduct | denotes | NEK2 | NCBIGene:4751 |
12178 | 2172-2189 | DiseaseOrPhenotypicFeature | denotes | metastasis of HCC | MESH:D006528|MESH:D009362 |
12179 | 2229-2232 | GeneOrGeneProduct | denotes | AKT | NCBIGene:207 |
12180 | 2260-2265 | GeneOrGeneProduct | denotes | MMP-2 | NCBIGene:4130 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | 0007256 |
T2 | 57-66 | DiseaseOrPhenotypicFeature | denotes | carcinoma | 0004993 |
T3 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | 0007256 |
T4 | 296-305 | DiseaseOrPhenotypicFeature | denotes | carcinoma | 0004993 |
T5 | 757-763 | DiseaseOrPhenotypicFeature | denotes | Cancer | 0004992 |
T6 | 1738-1746 | DiseaseOrPhenotypicFeature | denotes | complete | 0700063 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-4 | GeneOrGeneProduct | denotes | NEK2 |
T2 | 5-11 | GeneOrGeneProduct | denotes | serves |
T3 | 85-91 | GeneOrGeneProduct | denotes | gene A |
T4 | 107-113 | GeneOrGeneProduct | denotes | kinase |
T5 | 117-121 | GeneOrGeneProduct | denotes | NEK2 |
T6 | 128-158 | GeneOrGeneProduct | denotes | microtubule-associated protein |
T7 | 164-173 | GeneOrGeneProduct | denotes | regulates |
T8 | 182-190 | GeneOrGeneProduct | denotes | assembly |
T9 | 200-205 | GeneOrGeneProduct | denotes | cells |
T10 | 273-277 | GeneOrGeneProduct | denotes | NEK2 |
T11 | 366-370 | GeneOrGeneProduct | denotes | cell |
T12 | 371-375 | GeneOrGeneProduct | denotes | line |
T13 | 401-406 | GeneOrGeneProduct | denotes | liver |
T14 | 407-411 | GeneOrGeneProduct | denotes | cell |
T15 | 412-416 | GeneOrGeneProduct | denotes | line |
T16 | 454-458 | GeneOrGeneProduct | denotes | NEK2 |
T17 | 510-523 | GeneOrGeneProduct | denotes | transcription |
T18 | 524-534 | GeneOrGeneProduct | denotes | polymerase |
T19 | 535-540 | GeneOrGeneProduct | denotes | chain |
T20 | 557-561 | GeneOrGeneProduct | denotes | cell |
T21 | 562-567 | GeneOrGeneProduct | denotes | lines |
T22 | 603-611 | GeneOrGeneProduct | denotes | tumorous |
T23 | 612-617 | GeneOrGeneProduct | denotes | liver |
T24 | 664-668 | GeneOrGeneProduct | denotes | NEK2 |
T25 | 738-747 | GeneOrGeneProduct | denotes | available |
T26 | 771-776 | GeneOrGeneProduct | denotes | Atlas |
T27 | 849-853 | GeneOrGeneProduct | denotes | NEK2 |
T28 | 871-876 | GeneOrGeneProduct | denotes | MMP-2 |
T29 | 921-926 | GeneOrGeneProduct | denotes | cases |
T30 | 959-967 | GeneOrGeneProduct | denotes | tumorous |
T31 | 968-973 | GeneOrGeneProduct | denotes | liver |
T32 | 1005-1012 | GeneOrGeneProduct | denotes | protein |
T33 | 1103-1107 | GeneOrGeneProduct | denotes | NEK2 |
T34 | 1129-1134 | GeneOrGeneProduct | denotes | MMP-2 |
T35 | 1165-1170 | GeneOrGeneProduct | denotes | total |
T36 | 1210-1214 | GeneOrGeneProduct | denotes | DEGs |
T37 | 1297-1300 | GeneOrGeneProduct | denotes | 313 |
T38 | 1328-1332 | GeneOrGeneProduct | denotes | NEK2 |
T39 | 1366-1369 | GeneOrGeneProduct | denotes | DEG |
T40 | 1373-1378 | GeneOrGeneProduct | denotes | cells |
T41 | 1418-1424 | GeneOrGeneProduct | denotes | listed |
T42 | 1481-1485 | GeneOrGeneProduct | denotes | NEK2 |
T43 | 1511-1516 | GeneOrGeneProduct | denotes | cells |
T44 | 1572-1576 | GeneOrGeneProduct | denotes | high |
T45 | 1591-1595 | GeneOrGeneProduct | denotes | NEK2 |
T46 | 1596-1601 | GeneOrGeneProduct | denotes | had a |
T47 | 1684-1688 | GeneOrGeneProduct | denotes | NEK2 |
T48 | 1758-1763 | GeneOrGeneProduct | denotes | tumor |
T49 | 1814-1818 | GeneOrGeneProduct | denotes | NEK2 |
T50 | 1913-1918 | GeneOrGeneProduct | denotes | MMP-2 |
T51 | 1956-1960 | GeneOrGeneProduct | denotes | NEK2 |
T52 | 2060-2064 | GeneOrGeneProduct | denotes | NEK2 |
T53 | 2065-2071 | GeneOrGeneProduct | denotes | serves |
T54 | 2121-2133 | GeneOrGeneProduct | denotes | NEK2 protein |
T55 | 2215-2225 | GeneOrGeneProduct | denotes | activation |
T56 | 2260-2265 | GeneOrGeneProduct | denotes | MMP-2 |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-4 | GeneOrGeneProduct | denotes | NEK2 |
T2 | 85-91 | GeneOrGeneProduct | denotes | gene A |
T3 | 107-113 | GeneOrGeneProduct | denotes | kinase |
T4 | 117-121 | GeneOrGeneProduct | denotes | NEK2 |
T5 | 128-158 | GeneOrGeneProduct | denotes | microtubule-associated protein |
T6 | 182-190 | GeneOrGeneProduct | denotes | assembly |
T7 | 273-277 | GeneOrGeneProduct | denotes | NEK2 |
T8 | 366-370 | GeneOrGeneProduct | denotes | cell |
T9 | 401-406 | GeneOrGeneProduct | denotes | liver |
T10 | 407-411 | GeneOrGeneProduct | denotes | cell |
T11 | 454-458 | GeneOrGeneProduct | denotes | NEK2 |
T12 | 510-523 | GeneOrGeneProduct | denotes | transcription |
T13 | 524-534 | GeneOrGeneProduct | denotes | polymerase |
T14 | 535-540 | GeneOrGeneProduct | denotes | chain |
T15 | 557-561 | GeneOrGeneProduct | denotes | cell |
T16 | 562-567 | GeneOrGeneProduct | denotes | lines |
T17 | 603-611 | GeneOrGeneProduct | denotes | tumorous |
T18 | 612-617 | GeneOrGeneProduct | denotes | liver |
T19 | 664-668 | GeneOrGeneProduct | denotes | NEK2 |
T20 | 849-853 | GeneOrGeneProduct | denotes | NEK2 |
T21 | 871-876 | GeneOrGeneProduct | denotes | MMP-2 |
T22 | 959-967 | GeneOrGeneProduct | denotes | tumorous |
T23 | 968-973 | GeneOrGeneProduct | denotes | liver |
T24 | 1005-1012 | GeneOrGeneProduct | denotes | protein |
T25 | 1103-1107 | GeneOrGeneProduct | denotes | NEK2 |
T26 | 1129-1134 | GeneOrGeneProduct | denotes | MMP-2 |
T27 | 1297-1300 | GeneOrGeneProduct | denotes | 313 |
T28 | 1328-1332 | GeneOrGeneProduct | denotes | NEK2 |
T29 | 1481-1485 | GeneOrGeneProduct | denotes | NEK2 |
T30 | 1572-1576 | GeneOrGeneProduct | denotes | high |
T31 | 1591-1595 | GeneOrGeneProduct | denotes | NEK2 |
T32 | 1684-1688 | GeneOrGeneProduct | denotes | NEK2 |
T33 | 1814-1818 | GeneOrGeneProduct | denotes | NEK2 |
T34 | 1913-1918 | GeneOrGeneProduct | denotes | MMP-2 |
T35 | 1956-1960 | GeneOrGeneProduct | denotes | NEK2 |
T36 | 2060-2064 | GeneOrGeneProduct | denotes | NEK2 |
T37 | 2121-2133 | GeneOrGeneProduct | denotes | NEK2 protein |
T38 | 2260-2265 | GeneOrGeneProduct | denotes | MMP-2 |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T2 | 238-250 | DiseaseOrPhenotypicFeature | denotes | malignancies | D009369 |
T3 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T4 | 307-310 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T6 | 362-365 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T8 | 582-585 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T10 | 603-611 | DiseaseOrPhenotypicFeature | denotes | tumorous | D009369 |
T11 | 714-717 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T13 | 757-763 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 |
T14 | 930-933 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T16 | 959-967 | DiseaseOrPhenotypicFeature | denotes | tumorous | D009369 |
T17 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T19 | 1431-1434 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T21 | 1507-1510 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T23 | 1552-1555 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T25 | 1692-1695 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T27 | 1758-1763 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
T28 | 1792-1802 | DiseaseOrPhenotypicFeature | denotes | recurrence | D012008 |
T29 | 2102-2105 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T31 | 2172-2182 | DiseaseOrPhenotypicFeature | denotes | metastasis | D009362 |
T32 | 2186-2189 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-4 | GeneOrGeneProduct | denotes | NEK2 |
T2 | 92-113 | GeneOrGeneProduct | denotes | (NIMA)-related kinase |
T3 | 117-121 | GeneOrGeneProduct | denotes | NEK2 |
T4 | 128-158 | GeneOrGeneProduct | denotes | microtubule-associated protein |
T5 | 273-277 | GeneOrGeneProduct | denotes | NEK2 |
T6 | 454-458 | GeneOrGeneProduct | denotes | NEK2 |
T7 | 603-611 | GeneOrGeneProduct | denotes | tumorous |
T8 | 664-668 | GeneOrGeneProduct | denotes | NEK2 |
T9 | 849-853 | GeneOrGeneProduct | denotes | NEK2 |
T10 | 871-876 | GeneOrGeneProduct | denotes | MMP-2 |
T11 | 959-967 | GeneOrGeneProduct | denotes | tumorous |
T12 | 1005-1023 | GeneOrGeneProduct | denotes | protein expression |
T13 | 1103-1107 | GeneOrGeneProduct | denotes | NEK2 |
T14 | 1129-1134 | GeneOrGeneProduct | denotes | MMP-2 |
T15 | 1297-1300 | GeneOrGeneProduct | denotes | 313 |
T16 | 1328-1332 | GeneOrGeneProduct | denotes | NEK2 |
T17 | 1481-1485 | GeneOrGeneProduct | denotes | NEK2 |
T18 | 1591-1595 | GeneOrGeneProduct | denotes | NEK2 |
T19 | 1684-1688 | GeneOrGeneProduct | denotes | NEK2 |
T20 | 1814-1818 | GeneOrGeneProduct | denotes | NEK2 |
T21 | 1913-1918 | GeneOrGeneProduct | denotes | MMP-2 |
T22 | 1956-1960 | GeneOrGeneProduct | denotes | NEK2 |
T23 | 2060-2064 | GeneOrGeneProduct | denotes | NEK2 |
T24 | 2121-2133 | GeneOrGeneProduct | denotes | NEK2 protein |
T25 | 2260-2265 | GeneOrGeneProduct | denotes | MMP-2 |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | 0007256 |
T2 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | 0007256 |
T3 | 307-310 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T4 | 362-365 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T5 | 417-419 | DiseaseOrPhenotypicFeature | denotes | HL | 0004952 |
T6 | 582-585 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T7 | 714-717 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T8 | 930-933 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T9 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T10 | 1431-1434 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T11 | 1507-1510 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T12 | 1552-1555 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T13 | 1692-1695 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T14 | 1758-1763 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
T15 | 2102-2105 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
T16 | 2186-2189 | DiseaseOrPhenotypicFeature | denotes | HCC | 0007256 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T2 | 238-250 | DiseaseOrPhenotypicFeature | denotes | malignancies | D009369 |
T3 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T4 | 307-310 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T6 | 362-365 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T8 | 582-585 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T10 | 714-717 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T12 | 757-763 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 |
T13 | 930-933 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T15 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T17 | 1431-1434 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T19 | 1507-1510 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T21 | 1552-1555 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T23 | 1692-1695 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T25 | 1758-1763 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
T26 | 1792-1802 | DiseaseOrPhenotypicFeature | denotes | recurrence | D012008 |
T27 | 2102-2105 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T29 | 2172-2182 | DiseaseOrPhenotypicFeature | denotes | metastasis | D009362 |
T30 | 2186-2189 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T2 | 238-250 | DiseaseOrPhenotypicFeature | denotes | malignancies | D009369 |
T3 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 |
T4 | 307-310 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T6 | 362-365 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T8 | 582-585 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T10 | 714-717 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T12 | 757-763 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 |
T13 | 930-933 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T15 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T17 | 1431-1434 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T19 | 1507-1510 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T21 | 1552-1555 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T23 | 1692-1695 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T25 | 1758-1763 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
T26 | 2102-2105 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
T28 | 2186-2189 | DiseaseOrPhenotypicFeature | denotes | HCC | DISEASE|D006528 |
LitCoin_CellLine
Id | Subject | Object | Predicate | Lexical cue | cellosaurus_accession_id |
---|---|---|---|---|---|
T1 | 376-385 | CellLine | denotes | SMMC-7721 | CVCL_0534 |
T2 | 417-424 | CellLine | denotes | HL-7702 | CVCL_6926 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 85-91 | OrganismTaxon | denotes | gene A |
T2 | 194-199 | OrganismTaxon | denotes | human |
T3 | 700-708 | OrganismTaxon | denotes | patients |
T4 | 1556-1564 | OrganismTaxon | denotes | patients |
T5 | 2026-2033 | OrganismTaxon | denotes | patient |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 435-438 | ChemicalEntity | denotes | Ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
T2 | 855-862 | ChemicalEntity | denotes | phospho | http://purl.obolibrary.org/obo/CHEBI_48108 |
T3 | 1113-1120 | ChemicalEntity | denotes | phospho | http://purl.obolibrary.org/obo/CHEBI_48108 |
T4 | 1879-1886 | ChemicalEntity | denotes | phospho | http://purl.obolibrary.org/obo/CHEBI_48108 |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: | cellosaurus_accession_id |
---|---|---|---|---|---|---|---|
T2 | 417-424 | CellLine | denotes | HL-7702 | CVCL_6926 | ||
T1 | 376-385 | CellLine | denotes | SMMC-7721 | CVCL_0534 | ||
T4 | 1879-1886 | ChemicalEntity | denotes | phospho | http://purl.obolibrary.org/obo/CHEBI_48108 | ||
T3 | 1113-1120 | ChemicalEntity | denotes | phospho | http://purl.obolibrary.org/obo/CHEBI_48108 | ||
T89676 | 855-862 | ChemicalEntity | denotes | phospho | http://purl.obolibrary.org/obo/CHEBI_48108 | ||
T30977 | 435-438 | ChemicalEntity | denotes | Ion | http://purl.obolibrary.org/obo/CHEBI_24870 | ||
T25 | 2260-2265 | GeneOrGeneProduct | denotes | MMP-2 | |||
T24 | 2121-2133 | GeneOrGeneProduct | denotes | NEK2 protein | |||
T23 | 2060-2064 | GeneOrGeneProduct | denotes | NEK2 | |||
T22 | 1956-1960 | GeneOrGeneProduct | denotes | NEK2 | |||
T21 | 1913-1918 | GeneOrGeneProduct | denotes | MMP-2 | |||
T20 | 1814-1818 | GeneOrGeneProduct | denotes | NEK2 | |||
T19 | 1684-1688 | GeneOrGeneProduct | denotes | NEK2 | |||
T18 | 1591-1595 | GeneOrGeneProduct | denotes | NEK2 | |||
T17 | 1481-1485 | GeneOrGeneProduct | denotes | NEK2 | |||
T16 | 1328-1332 | GeneOrGeneProduct | denotes | NEK2 | |||
T15 | 1297-1300 | GeneOrGeneProduct | denotes | 313 | |||
T14 | 1129-1134 | GeneOrGeneProduct | denotes | MMP-2 | |||
T13 | 1103-1107 | GeneOrGeneProduct | denotes | NEK2 | |||
T12 | 1005-1023 | GeneOrGeneProduct | denotes | protein expression | |||
T11 | 959-967 | GeneOrGeneProduct | denotes | tumorous | |||
T10 | 871-876 | GeneOrGeneProduct | denotes | MMP-2 | |||
T9 | 849-853 | GeneOrGeneProduct | denotes | NEK2 | |||
T8 | 664-668 | GeneOrGeneProduct | denotes | NEK2 | |||
T7 | 603-611 | GeneOrGeneProduct | denotes | tumorous | |||
T6 | 454-458 | GeneOrGeneProduct | denotes | NEK2 | |||
T5 | 273-277 | GeneOrGeneProduct | denotes | NEK2 | |||
T5895 | 128-158 | GeneOrGeneProduct | denotes | microtubule-associated protein | |||
T31625 | 117-121 | GeneOrGeneProduct | denotes | NEK2 | |||
T20161 | 92-113 | GeneOrGeneProduct | denotes | (NIMA)-related kinase | |||
T24682 | 0-4 | GeneOrGeneProduct | denotes | NEK2 | |||
T28 | 2186-2189 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T26 | 2102-2105 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T19501 | 1758-1763 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
T76607 | 1692-1695 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T9780 | 1552-1555 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T75054 | 1507-1510 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T28049 | 1431-1434 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T13673 | 1323-1326 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T31869 | 930-933 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T30127 | 757-763 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 | ||
T24324 | 714-717 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T11630 | 582-585 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T43375 | 362-365 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T55422 | 307-310 | DiseaseOrPhenotypicFeature | denotes | HCC | D006528|DISEASE | ||
T13354 | 281-305 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 | ||
T44458 | 238-250 | DiseaseOrPhenotypicFeature | denotes | malignancies | D009369 | ||
T62084 | 42-66 | DiseaseOrPhenotypicFeature | denotes | hepatocellular carcinoma | D006528 | ||
T26463 | 2026-2033 | OrganismTaxon | denotes | patient | |||
T22016 | 1556-1564 | OrganismTaxon | denotes | patients | |||
T64553 | 700-708 | OrganismTaxon | denotes | patients | |||
T49559 | 194-199 | OrganismTaxon | denotes | human | |||
T2993 | 85-91 | OrganismTaxon | denotes | gene A |