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PubMed:2792202 JSONTXT

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PubmedHPO

Id Subject Object Predicate Lexical cue
T1 679-689 HP_0002380 denotes fascicules
T2 922-932 HP_0002380 denotes fascicules

Oryza_sentences

Id Subject Object Predicate Lexical cue
T1 0-79 Sentence denotes Effects of dietary vitamin E supplement on gracile axonal dystrophy (gad) mice.
T2 80-226 Sentence denotes We have studied the effects of dietary vitamin E supplement on the clinical signs and pathological changes in GAD (gracile axonal dystrophy) mice.
T3 227-413 Sentence denotes The control diet contained 2 mg of dl-alpha-tocopheryl acetate (2 I.U.) and vitamin E-supplemented diet contained 58.5 mg of dl-alpha-tocopheryl nicotinate (50 I.U.), per 100 mg of feed.
T4 414-501 Sentence denotes The diet was given to normal (gad/+) and GAD (gad/gad) mice from 21 to 130 days of age.
T5 502-617 Sentence denotes During the feeding, there was no improvement in clinical signs in the GAD mice fed the vitamin E-supplemented diet.
T6 618-855 Sentence denotes The gracile nucleus of the medulla oblongata and the gracile fascicules of the spinal cord were investigated for pathology at 130 days of age, and alpha-tocopherol was also assayed in the serum, liver, brain and spinal cord at that time.
T7 856-1002 Sentence denotes There were no pathological differences in the gracile nucleus and fascicules between the GAD mice fed the control and vitamin E-supplemented diet.
T8 1003-1220 Sentence denotes The alpha-tocopherol levels in the serum and target organs in the control GAD mice were not significantly different from those in control normal mice, showing that GAD mice could absorb and transport alpha-tocopherol.
T9 1221-1352 Sentence denotes In the supplemented GAD mice, no significant increases in alpha-tocopherol levels were observed in the liver, brain or spinal cord.
T10 1353-1613 Sentence denotes Particularly, the percentage increase of alpha-tocopherol level in the liver of GAD mice was very low in comparison with that in normal mice, even though the liver can store vitamin E. Thus it may be that the capacity to store vitamin E is lowered in GAD mice.
T11 1614-1710 Sentence denotes Further studies are needed to investigate in detail the vitamin E metabolism in the mutant mice.