PubMed:2788166 / 1396-1712 JSONTXT

{"project":"Inflammaging","denotations":[{"id":"T8","span":{"begin":0,"end":316},"obj":"Sentence"},{"id":"T8","span":{"begin":0,"end":316},"obj":"Sentence"}],"text":"Evaluation of de novo alpha 1AT biosynthesis in alpha 1AT-synthesizing cells of this individual demonstrated normal levels of alpha 1AT mRNA transcripts but abnormal intracellular accumulation of newly synthesized alpha 1AT at the level of the rough endoplasmic reticulum with consequent reduced alpha 1AT secretion."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T8","span":{"begin":0,"end":316},"obj":"Sentence"},{"id":"T8","span":{"begin":0,"end":316},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Evaluation of de novo alpha 1AT biosynthesis in alpha 1AT-synthesizing cells of this individual demonstrated normal levels of alpha 1AT mRNA transcripts but abnormal intracellular accumulation of newly synthesized alpha 1AT at the level of the rough endoplasmic reticulum with consequent reduced alpha 1AT secretion."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T7","span":{"begin":166,"end":179},"obj":"Body_part"},{"id":"T8","span":{"begin":262,"end":271},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/GO_0005622"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0007361"}],"text":"Evaluation of de novo alpha 1AT biosynthesis in alpha 1AT-synthesizing cells of this individual demonstrated normal levels of alpha 1AT mRNA transcripts but abnormal intracellular accumulation of newly synthesized alpha 1AT at the level of the rough endoplasmic reticulum with consequent reduced alpha 1AT secretion."}