PubMed:27783098 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/27783098","sourcedb":"PubMed","sourceid":"27783098","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/27783098","text":"[Degenerative cerebellar diseases and differential diagnoses].\nDegenerative Kleinhirnerkrankungen und Differenzialdiagnosen.\nCLINICAL/METHODICAL ISSUE: Cerebellar syndromes result in distinct clinical symptoms, such as ataxia, dysarthria, dysmetria, intention tremor and eye movement disorders.\nSTANDARD RADIOLOGICAL METHODS: In addition to the medical history and clinical examination, imaging is particularly important to differentiate other diseases, such as hydrocephalus and multi-infarct dementia from degenerative cerebellar diseases. Degenerative diseases with cerebellar involvement include Parkinson's disease, multiple system atrophy as well as other diseases including spinocerebellar ataxia.\nACHIEVEMENTS: In addition to magnetic resonance imaging (MRI), nuclear medicine imaging investigations are also helpful for the differentiation.\nPRACTICAL RECOMMENDATIONS: Axial fluid-attenuated inversion recovery (FLAIR) and T2-weighted sequences can sometimes show a signal increase in the pons as a sign of degeneration of pontine neurons and transverse fibers in the basilar part of the pons. 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