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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-160 Sentence denotes One-step partial or complete caries removal and bonding with antibacterial or traditional self-etch adhesives: study protocol for a randomized controlled trial.
T2 161-172 Sentence denotes BACKGROUND:
T3 173-285 Sentence denotes Current concepts in conservative dentistry advocate minimally invasive dentistry and pulp vitality preservation.
T4 286-464 Sentence denotes Moreover, complete removal of carious dentin in deep carious lesions often leads to pulp exposure and root canal treatment, despite the absence of irreversible pulp inflammation.
T5 465-603 Sentence denotes For years, partial caries removal has been performed on primary teeth, but little evidence supports its effectiveness for permanent teeth.
T6 604-732 Sentence denotes Furthermore, the recent development of new antibacterial adhesive systems could be interesting in the treatment of such lesions.
T7 733-996 Sentence denotes The objectives of this study are to compare the effectiveness of partial versus complete carious dentin removal in deep lesions (primary objective) and the use of an antibacterial versus a traditional two-step self-etch adhesive system (main secondary objective).
T8 997-1012 Sentence denotes METHODS/DESIGN:
T9 1013-1203 Sentence denotes The DEep CAries Treatment (DECAT) study protocol is a multicenter, randomized, controlled superiority trial comparing partial versus complete caries removal followed by adhesive restoration.
T10 1204-1253 Sentence denotes The minimum sample size required is 464 patients.
T11 1254-1505 Sentence denotes Two successive randomizations will be performed (allocation ratio 1:1): the first for the type of excavation (partial versus complete) and the second (if no root canal treatment is required) for the type of adhesive (antibacterial versus traditional).
T12 1506-1839 Sentence denotes For the two objectives, the outcome is the success of the treatment after 1 year, measured according to a composite outcome of five FDI criteria: material fracture and retention, marginal adaptation, radiographic examination (including apical pathologies), postoperative sensitivity and tooth vitality, and carious lesion recurrence.
T13 1840-1851 Sentence denotes DISCUSSION:
T14 1852-2023 Sentence denotes The study will investigate the interest of a conservative approach for the management of deep carious lesions in terms of dentin excavation and bioactive adhesive systems.
T15 2024-2173 Sentence denotes The results may help practitioners achieve the most efficient restorative procedure to maintain pulp vitality and increase the restoration longevity.
T16 2174-2193 Sentence denotes TRIAL REGISTRATION:
T17 2194-2237 Sentence denotes ClinicalTrials.gov Identifier NCT02286388 .
T18 2238-2266 Sentence denotes Registered in November 2014.
T1 0-160 Sentence denotes One-step partial or complete caries removal and bonding with antibacterial or traditional self-etch adhesives: study protocol for a randomized controlled trial.
T2 161-172 Sentence denotes BACKGROUND:
T3 173-285 Sentence denotes Current concepts in conservative dentistry advocate minimally invasive dentistry and pulp vitality preservation.
T4 286-464 Sentence denotes Moreover, complete removal of carious dentin in deep carious lesions often leads to pulp exposure and root canal treatment, despite the absence of irreversible pulp inflammation.
T5 465-603 Sentence denotes For years, partial caries removal has been performed on primary teeth, but little evidence supports its effectiveness for permanent teeth.
T6 604-732 Sentence denotes Furthermore, the recent development of new antibacterial adhesive systems could be interesting in the treatment of such lesions.
T7 733-996 Sentence denotes The objectives of this study are to compare the effectiveness of partial versus complete carious dentin removal in deep lesions (primary objective) and the use of an antibacterial versus a traditional two-step self-etch adhesive system (main secondary objective).
T8 997-1012 Sentence denotes METHODS/DESIGN:
T9 1013-1203 Sentence denotes The DEep CAries Treatment (DECAT) study protocol is a multicenter, randomized, controlled superiority trial comparing partial versus complete caries removal followed by adhesive restoration.
T10 1204-1253 Sentence denotes The minimum sample size required is 464 patients.
T11 1254-1505 Sentence denotes Two successive randomizations will be performed (allocation ratio 1:1): the first for the type of excavation (partial versus complete) and the second (if no root canal treatment is required) for the type of adhesive (antibacterial versus traditional).
T12 1506-1839 Sentence denotes For the two objectives, the outcome is the success of the treatment after 1 year, measured according to a composite outcome of five FDI criteria: material fracture and retention, marginal adaptation, radiographic examination (including apical pathologies), postoperative sensitivity and tooth vitality, and carious lesion recurrence.
T13 1840-1851 Sentence denotes DISCUSSION:
T14 1852-2023 Sentence denotes The study will investigate the interest of a conservative approach for the management of deep carious lesions in terms of dentin excavation and bioactive adhesive systems.
T15 2024-2173 Sentence denotes The results may help practitioners achieve the most efficient restorative procedure to maintain pulp vitality and increase the restoration longevity.
T16 2174-2193 Sentence denotes TRIAL REGISTRATION:
T17 2194-2237 Sentence denotes ClinicalTrials.gov Identifier NCT02286388 .
T18 2238-2266 Sentence denotes Registered in November 2014.