PubMed:27464336
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T12 | 1304-1433 | Sentence | denotes | Alcohol also increased eEF2K phosphorylation and decreased eEF2 phosphorylation consistent with increased translation elongation. |
| T1 | 0-194 | Sentence | denotes | Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue. |
| T2 | 195-206 | Sentence | denotes | BACKGROUND: |
| T3 | 207-359 | Sentence | denotes | Chronic alcohol consumption leads to a loss of white adipose tissue (WAT) but the underlying mechanisms for this lipodystrophy are not fully elucidated. |
| T4 | 360-583 | Sentence | denotes | This study tested the hypothesis that the reduction in WAT mass in chronic alcohol-fed mice is associated with a decreased protein synthesis specifically related to impaired function of mammalian target of rapamycin (mTOR). |
| T5 | 584-592 | Sentence | denotes | METHODS: |
| T6 | 593-715 | Sentence | denotes | Adult male mice were provided an alcohol-containing liquid diet for 24 weeks or an isonitrogenous isocaloric control diet. |
| T7 | 716-920 | Sentence | denotes | In vivo protein synthesis was determined at this time and thereafter epididymal WAT (eWAT) was excised for analysis of signal transduction pathways central to controling protein synthesis and degradation. |
| T8 | 921-929 | Sentence | denotes | RESULTS: |
| T9 | 930-1072 | Sentence | denotes | While chronic alcohol feeding decreased whole-body and eWAT mass, this was associated with a discordant increase in protein synthesis in eWAT. |
| T10 | 1073-1168 | Sentence | denotes | This increase was not associated with a change in mTOR, 4E-BP1, Akt, or PRAS40 phosphorylation. |
| T11 | 1169-1303 | Sentence | denotes | Instead, a selective increase in phosphorylation of S6K1 and its downstream substrates, S6 and eIF4B was detected in alcohol-fed mice. |
| T13 | 1434-1619 | Sentence | denotes | Alcohol increased Atg12-5, LC3B-I and -II, and ULK1 S555 phosphorylation, suggesting increased autophagy, while markers of apoptosis (cleaved caspase-3 and -9, and PARP) were unchanged. |
| T14 | 1620-1762 | Sentence | denotes | Lipolytic enzymes (ATGL and HSL phosphorylation) were increased and lipogenic regulators (PPARγ and C/EBPα) were decreased in eWAT by alcohol. |
| T15 | 1763-1969 | Sentence | denotes | Although alcohol increased TNF-α, IL-6, and IL-1β mRNA, no change in key components of the NLRP3 inflammasome (NLRP3, ACS, and cleaved caspase-1) was detected suggesting alcohol did not increase pyroptosis. |
| T16 | 1970-2015 | Sentence | denotes | Plasma insulin did not differ between groups. |
| T17 | 2016-2028 | Sentence | denotes | CONCLUSIONS: |
| T18 | 2029-2263 | Sentence | denotes | These results demonstrate that the alcohol-induced decrease in whole-body fat mass resulted in part from activation of autophagy in eWAT as protein synthesis was increased and mediated by the specific increase in the activity of S6K1. |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 447-451 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T3 | 604-608 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T5 | 1298-1302 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 11383 | 50-57 | ChemicalEntity | denotes | Alcohol | MESH:D000438 |
| 11384 | 103-107 | GeneOrGeneProduct | denotes | S6K1 | NCBIGene:72508 |
| 11385 | 215-222 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11386 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | MESH:D008060 |
| 11387 | 435-442 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11388 | 447-451 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 11389 | 546-575 | GeneOrGeneProduct | denotes | mammalian target of rapamycin | NCBIGene:56717 |
| 11390 | 577-581 | GeneOrGeneProduct | denotes | mTOR | NCBIGene:56717 |
| 11391 | 604-608 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 11392 | 626-633 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11393 | 944-951 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11394 | 1123-1127 | GeneOrGeneProduct | denotes | mTOR | NCBIGene:56717 |
| 11395 | 1129-1135 | GeneOrGeneProduct | denotes | 4E-BP1 | NCBIGene:13685 |
| 11396 | 1137-1140 | GeneOrGeneProduct | denotes | Akt | NCBIGene:11651 |
| 11397 | 1145-1151 | GeneOrGeneProduct | denotes | PRAS40 | NCBIGene:67605 |
| 11398 | 1221-1225 | GeneOrGeneProduct | denotes | S6K1 | NCBIGene:72508 |
| 11399 | 1257-1259 | GeneOrGeneProduct | denotes | S6 | NCBIGene:20104 |
| 11400 | 1264-1269 | GeneOrGeneProduct | denotes | eIF4B | NCBIGene:75705 |
| 11401 | 1286-1293 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11402 | 1298-1302 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 11403 | 1304-1311 | ChemicalEntity | denotes | Alcohol | MESH:D000438 |
| 11404 | 1327-1332 | GeneOrGeneProduct | denotes | eEF2K | NCBIGene:13631 |
| 11405 | 1363-1367 | GeneOrGeneProduct | denotes | eEF2 | NCBIGene:13629 |
| 11406 | 1434-1441 | ChemicalEntity | denotes | Alcohol | MESH:D000438 |
| 11407 | 1452-1459 | GeneOrGeneProduct | denotes | Atg12-5 | NCBIGene:11793|NCBIGene:67526 |
| 11408 | 1461-1475 | GeneOrGeneProduct | denotes | LC3B-I and -II | NCBIGene:67443 |
| 11409 | 1481-1485 | GeneOrGeneProduct | denotes | ULK1 | NCBIGene:22241 |
| 11410 | 1486-1490 | SequenceVariant | denotes | S555 | p|Allele|S|555 |
| 11411 | 1576-1592 | GeneOrGeneProduct | denotes | caspase-3 and -9 | NCBIGene:12367|NCBIGene:12371 |
| 11412 | 1598-1602 | GeneOrGeneProduct | denotes | PARP | NCBIGene:11545 |
| 11413 | 1639-1643 | GeneOrGeneProduct | denotes | ATGL | NCBIGene:66853 |
| 11414 | 1648-1651 | GeneOrGeneProduct | denotes | HSL | NCBIGene:16890 |
| 11415 | 1710-1715 | GeneOrGeneProduct | denotes | PPARγ | NCBIGene:19016 |
| 11416 | 1720-1726 | GeneOrGeneProduct | denotes | C/EBPα | NCBIGene:12606 |
| 11417 | 1754-1761 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11418 | 1772-1779 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11419 | 1790-1795 | GeneOrGeneProduct | denotes | TNF-α | NCBIGene:21926 |
| 11420 | 1797-1801 | GeneOrGeneProduct | denotes | IL-6 | NCBIGene:16193 |
| 11421 | 1807-1812 | GeneOrGeneProduct | denotes | IL-1β | NCBIGene:16176 |
| 11422 | 1854-1859 | GeneOrGeneProduct | denotes | NLRP3 | NCBIGene:216799 |
| 11423 | 1874-1879 | GeneOrGeneProduct | denotes | NLRP3 | NCBIGene:216799 |
| 11424 | 1881-1884 | GeneOrGeneProduct | denotes | ACS | NCBIGene:66824 |
| 11425 | 1898-1907 | GeneOrGeneProduct | denotes | caspase-1 | NCBIGene:12362 |
| 11426 | 1933-1940 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11427 | 1977-1984 | GeneOrGeneProduct | denotes | insulin | NCBIGene:16334 |
| 11428 | 2064-2071 | ChemicalEntity | denotes | alcohol | MESH:D000438 |
| 11429 | 2258-2262 | GeneOrGeneProduct | denotes | S6K1 | NCBIGene:72508 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 162-172 | DiseaseOrPhenotypicFeature | denotes | Epididymal | 0004779 |
| T2 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | 0006573 |
| T3 | 785-795 | DiseaseOrPhenotypicFeature | denotes | epididymal | 0004779 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 25-29 | GeneOrGeneProduct | denotes | Mass |
| T2 | 50-57 | GeneOrGeneProduct | denotes | Alcohol |
| T3 | 89-99 | GeneOrGeneProduct | denotes | Activation |
| T4 | 103-107 | GeneOrGeneProduct | denotes | S6K1 |
| T5 | 108-116 | GeneOrGeneProduct | denotes | Mediated |
| T6 | 117-124 | GeneOrGeneProduct | denotes | Protein |
| T7 | 149-158 | GeneOrGeneProduct | denotes | Autophagy |
| T8 | 173-178 | GeneOrGeneProduct | denotes | White |
| T9 | 179-186 | GeneOrGeneProduct | denotes | Adipose |
| T10 | 215-222 | GeneOrGeneProduct | denotes | alcohol |
| T11 | 254-259 | GeneOrGeneProduct | denotes | white |
| T12 | 260-267 | GeneOrGeneProduct | denotes | adipose |
| T13 | 371-377 | GeneOrGeneProduct | denotes | tested |
| T14 | 419-423 | GeneOrGeneProduct | denotes | mass |
| T15 | 435-442 | GeneOrGeneProduct | denotes | alcohol |
| T16 | 447-451 | GeneOrGeneProduct | denotes | mice |
| T17 | 483-490 | GeneOrGeneProduct | denotes | protein |
| T18 | 546-575 | GeneOrGeneProduct | denotes | mammalian target of rapamycin |
| T19 | 577-581 | GeneOrGeneProduct | denotes | mTOR |
| T20 | 584-591 | GeneOrGeneProduct | denotes | METHODS |
| T21 | 599-603 | GeneOrGeneProduct | denotes | male |
| T22 | 604-608 | GeneOrGeneProduct | denotes | mice |
| T23 | 626-633 | GeneOrGeneProduct | denotes | alcohol |
| T24 | 657-663 | GeneOrGeneProduct | denotes | for 24 |
| T25 | 724-731 | GeneOrGeneProduct | denotes | protein |
| T26 | 746-756 | GeneOrGeneProduct | denotes | determined |
| T27 | 765-769 | GeneOrGeneProduct | denotes | time |
| T28 | 811-818 | GeneOrGeneProduct | denotes | excised |
| T29 | 835-854 | GeneOrGeneProduct | denotes | signal transduction |
| T30 | 886-893 | GeneOrGeneProduct | denotes | protein |
| T31 | 944-951 | GeneOrGeneProduct | denotes | alcohol |
| T32 | 990-994 | GeneOrGeneProduct | denotes | mass |
| T33 | 1046-1053 | GeneOrGeneProduct | denotes | protein |
| T34 | 1123-1127 | GeneOrGeneProduct | denotes | mTOR |
| T35 | 1129-1135 | GeneOrGeneProduct | denotes | 4E-BP1 |
| T36 | 1145-1151 | GeneOrGeneProduct | denotes | PRAS40 |
| T37 | 1221-1225 | GeneOrGeneProduct | denotes | S6K1 |
| T38 | 1264-1269 | GeneOrGeneProduct | denotes | eIF4B |
| T39 | 1286-1293 | GeneOrGeneProduct | denotes | alcohol |
| T40 | 1298-1302 | GeneOrGeneProduct | denotes | mice |
| T41 | 1304-1311 | GeneOrGeneProduct | denotes | Alcohol |
| T42 | 1327-1332 | GeneOrGeneProduct | denotes | eEF2K |
| T43 | 1363-1367 | GeneOrGeneProduct | denotes | eEF2 |
| T44 | 1422-1432 | GeneOrGeneProduct | denotes | elongation |
| T45 | 1434-1441 | GeneOrGeneProduct | denotes | Alcohol |
| T46 | 1452-1457 | GeneOrGeneProduct | denotes | Atg12 |
| T47 | 1461-1465 | GeneOrGeneProduct | denotes | LC3B |
| T48 | 1473-1475 | GeneOrGeneProduct | denotes | II |
| T49 | 1481-1485 | GeneOrGeneProduct | denotes | ULK1 |
| T50 | 1529-1538 | GeneOrGeneProduct | denotes | autophagy |
| T51 | 1557-1566 | GeneOrGeneProduct | denotes | apoptosis |
| T52 | 1576-1585 | GeneOrGeneProduct | denotes | caspase-3 |
| T53 | 1598-1602 | GeneOrGeneProduct | denotes | PARP |
| T54 | 1620-1637 | GeneOrGeneProduct | denotes | Lipolytic enzymes |
| T55 | 1639-1643 | GeneOrGeneProduct | denotes | ATGL |
| T56 | 1698-1708 | GeneOrGeneProduct | denotes | regulators |
| T57 | 1710-1714 | GeneOrGeneProduct | denotes | PPAR |
| T58 | 1720-1725 | GeneOrGeneProduct | denotes | C/EBP |
| T59 | 1754-1761 | GeneOrGeneProduct | denotes | alcohol |
| T60 | 1772-1779 | GeneOrGeneProduct | denotes | alcohol |
| T61 | 1797-1801 | GeneOrGeneProduct | denotes | IL-6 |
| T62 | 1807-1811 | GeneOrGeneProduct | denotes | IL-1 |
| T63 | 1813-1817 | GeneOrGeneProduct | denotes | mRNA |
| T64 | 1854-1859 | GeneOrGeneProduct | denotes | NLRP3 |
| T65 | 1874-1879 | GeneOrGeneProduct | denotes | NLRP3 |
| T66 | 1898-1907 | GeneOrGeneProduct | denotes | caspase-1 |
| T67 | 1933-1940 | GeneOrGeneProduct | denotes | alcohol |
| T68 | 1977-1984 | GeneOrGeneProduct | denotes | insulin |
| T69 | 2064-2071 | GeneOrGeneProduct | denotes | alcohol |
| T70 | 2072-2079 | GeneOrGeneProduct | denotes | induced |
| T71 | 2107-2111 | GeneOrGeneProduct | denotes | mass |
| T72 | 2124-2128 | GeneOrGeneProduct | denotes | part |
| T73 | 2134-2144 | GeneOrGeneProduct | denotes | activation |
| T74 | 2148-2157 | GeneOrGeneProduct | denotes | autophagy |
| T75 | 2169-2176 | GeneOrGeneProduct | denotes | protein |
| T76 | 2205-2213 | GeneOrGeneProduct | denotes | mediated |
| T77 | 2246-2254 | GeneOrGeneProduct | denotes | activity |
| T78 | 2258-2262 | GeneOrGeneProduct | denotes | S6K1 |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-57 | GeneOrGeneProduct | denotes | Alcohol |
| T2 | 103-107 | GeneOrGeneProduct | denotes | S6K1 |
| T3 | 117-124 | GeneOrGeneProduct | denotes | Protein |
| T4 | 149-158 | GeneOrGeneProduct | denotes | Autophagy |
| T5 | 173-178 | GeneOrGeneProduct | denotes | White |
| T6 | 179-186 | GeneOrGeneProduct | denotes | Adipose |
| T7 | 215-222 | GeneOrGeneProduct | denotes | alcohol |
| T8 | 254-259 | GeneOrGeneProduct | denotes | white |
| T9 | 260-267 | GeneOrGeneProduct | denotes | adipose |
| T10 | 435-442 | GeneOrGeneProduct | denotes | alcohol |
| T11 | 483-490 | GeneOrGeneProduct | denotes | protein |
| T12 | 546-575 | GeneOrGeneProduct | denotes | mammalian target of rapamycin |
| T13 | 577-581 | GeneOrGeneProduct | denotes | mTOR |
| T14 | 626-633 | GeneOrGeneProduct | denotes | alcohol |
| T15 | 724-731 | GeneOrGeneProduct | denotes | protein |
| T16 | 835-854 | GeneOrGeneProduct | denotes | signal transduction |
| T17 | 886-893 | GeneOrGeneProduct | denotes | protein |
| T18 | 944-951 | GeneOrGeneProduct | denotes | alcohol |
| T19 | 1046-1053 | GeneOrGeneProduct | denotes | protein |
| T20 | 1123-1127 | GeneOrGeneProduct | denotes | mTOR |
| T21 | 1129-1135 | GeneOrGeneProduct | denotes | 4E-BP1 |
| T22 | 1145-1151 | GeneOrGeneProduct | denotes | PRAS40 |
| T23 | 1221-1225 | GeneOrGeneProduct | denotes | S6K1 |
| T24 | 1264-1269 | GeneOrGeneProduct | denotes | eIF4B |
| T25 | 1286-1293 | GeneOrGeneProduct | denotes | alcohol |
| T26 | 1304-1311 | GeneOrGeneProduct | denotes | Alcohol |
| T27 | 1327-1332 | GeneOrGeneProduct | denotes | eEF2K |
| T28 | 1363-1367 | GeneOrGeneProduct | denotes | eEF2 |
| T29 | 1434-1441 | GeneOrGeneProduct | denotes | Alcohol |
| T30 | 1452-1457 | GeneOrGeneProduct | denotes | Atg12 |
| T31 | 1461-1465 | GeneOrGeneProduct | denotes | LC3B |
| T32 | 1481-1485 | GeneOrGeneProduct | denotes | ULK1 |
| T33 | 1529-1538 | GeneOrGeneProduct | denotes | autophagy |
| T34 | 1557-1566 | GeneOrGeneProduct | denotes | apoptosis |
| T35 | 1576-1585 | GeneOrGeneProduct | denotes | caspase-3 |
| T36 | 1598-1602 | GeneOrGeneProduct | denotes | PARP |
| T37 | 1620-1637 | GeneOrGeneProduct | denotes | Lipolytic enzymes |
| T38 | 1639-1643 | GeneOrGeneProduct | denotes | ATGL |
| T39 | 1698-1708 | GeneOrGeneProduct | denotes | regulators |
| T40 | 1710-1714 | GeneOrGeneProduct | denotes | PPAR |
| T41 | 1720-1725 | GeneOrGeneProduct | denotes | C/EBP |
| T42 | 1754-1761 | GeneOrGeneProduct | denotes | alcohol |
| T43 | 1772-1779 | GeneOrGeneProduct | denotes | alcohol |
| T44 | 1797-1801 | GeneOrGeneProduct | denotes | IL-6 |
| T45 | 1807-1811 | GeneOrGeneProduct | denotes | IL-1 |
| T46 | 1813-1817 | GeneOrGeneProduct | denotes | mRNA |
| T47 | 1854-1859 | GeneOrGeneProduct | denotes | NLRP3 |
| T48 | 1874-1879 | GeneOrGeneProduct | denotes | NLRP3 |
| T49 | 1898-1907 | GeneOrGeneProduct | denotes | caspase-1 |
| T50 | 1933-1940 | GeneOrGeneProduct | denotes | alcohol |
| T51 | 1977-1984 | GeneOrGeneProduct | denotes | insulin |
| T52 | 2064-2071 | GeneOrGeneProduct | denotes | alcohol |
| T53 | 2148-2157 | GeneOrGeneProduct | denotes | autophagy |
| T54 | 2169-2176 | GeneOrGeneProduct | denotes | protein |
| T55 | 2258-2262 | GeneOrGeneProduct | denotes | S6K1 |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 215-222 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T2 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | D008060 |
| T3 | 435-442 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T4 | 626-633 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T5 | 944-951 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T6 | 1286-1293 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T7 | 1754-1761 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T8 | 1772-1779 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T9 | 1933-1940 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
| T10 | 2064-2071 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 103-107 | GeneOrGeneProduct | denotes | S6K1 |
| T2 | 173-178 | GeneOrGeneProduct | denotes | White |
| T3 | 254-259 | GeneOrGeneProduct | denotes | white |
| T4 | 546-575 | GeneOrGeneProduct | denotes | mammalian target of rapamycin |
| T5 | 577-581 | GeneOrGeneProduct | denotes | mTOR |
| T6 | 875-893 | GeneOrGeneProduct | denotes | controling protein |
| T7 | 1123-1127 | GeneOrGeneProduct | denotes | mTOR |
| T8 | 1129-1135 | GeneOrGeneProduct | denotes | 4E-BP1 |
| T9 | 1137-1140 | GeneOrGeneProduct | denotes | Akt |
| T10 | 1145-1151 | GeneOrGeneProduct | denotes | PRAS40 |
| T11 | 1221-1225 | GeneOrGeneProduct | denotes | S6K1 |
| T12 | 1264-1269 | GeneOrGeneProduct | denotes | eIF4B |
| T13 | 1327-1332 | GeneOrGeneProduct | denotes | eEF2K |
| T14 | 1363-1367 | GeneOrGeneProduct | denotes | eEF2 |
| T15 | 1452-1457 | GeneOrGeneProduct | denotes | Atg12 |
| T16 | 1461-1465 | GeneOrGeneProduct | denotes | LC3B |
| T17 | 1481-1485 | GeneOrGeneProduct | denotes | ULK1 |
| T18 | 1576-1585 | GeneOrGeneProduct | denotes | caspase-3 |
| T19 | 1598-1602 | GeneOrGeneProduct | denotes | PARP |
| T20 | 1620-1637 | GeneOrGeneProduct | denotes | Lipolytic enzymes |
| T21 | 1639-1643 | GeneOrGeneProduct | denotes | ATGL |
| T22 | 1710-1714 | GeneOrGeneProduct | denotes | PPAR |
| T23 | 1720-1725 | GeneOrGeneProduct | denotes | C/EBP |
| T24 | 1797-1801 | GeneOrGeneProduct | denotes | IL-6 |
| T25 | 1807-1811 | GeneOrGeneProduct | denotes | IL-1 |
| T26 | 1854-1859 | GeneOrGeneProduct | denotes | NLRP3 |
| T27 | 1874-1879 | GeneOrGeneProduct | denotes | NLRP3 |
| T28 | 1898-1907 | GeneOrGeneProduct | denotes | caspase-1 |
| T29 | 2258-2262 | GeneOrGeneProduct | denotes | S6K1 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 162-172 | DiseaseOrPhenotypicFeature | denotes | Epididymal | 0004779 |
| T2 | 276-279 | DiseaseOrPhenotypicFeature | denotes | WAT | 0004255 |
| T3 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | 0006573 |
| T4 | 415-418 | DiseaseOrPhenotypicFeature | denotes | WAT | 0004255 |
| T5 | 443-446 | DiseaseOrPhenotypicFeature | denotes | fed | 0007620 |
| T6 | 785-795 | DiseaseOrPhenotypicFeature | denotes | epididymal | 0004779 |
| T7 | 796-799 | DiseaseOrPhenotypicFeature | denotes | WAT | 0004255 |
| T8 | 1294-1297 | DiseaseOrPhenotypicFeature | denotes | fed | 0007620 |
| T9 | 1881-1884 | DiseaseOrPhenotypicFeature | denotes | ACS | 0019796|0008708|0005632 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | D008060 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | D008060 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 50-57 | ChemicalEntity | denotes | Alcohol | http://purl.obolibrary.org/obo/CHEBI_30879 |
| T2 | 215-222 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T5 | 435-442 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T8 | 566-575 | ChemicalEntity | denotes | rapamycin | D020123|http://purl.obolibrary.org/obo/CHEBI_9168 |
| T10 | 626-633 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T13 | 944-951 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T16 | 1286-1293 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T19 | 1304-1311 | ChemicalEntity | denotes | Alcohol | http://purl.obolibrary.org/obo/CHEBI_30879 |
| T20 | 1434-1441 | ChemicalEntity | denotes | Alcohol | http://purl.obolibrary.org/obo/CHEBI_30879 |
| T21 | 1648-1651 | ChemicalEntity | denotes | HSL | http://purl.obolibrary.org/obo/CHEBI_17289 |
| T22 | 1754-1761 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T25 | 1772-1779 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T28 | 1860-1872 | ChemicalEntity | denotes | inflammasome | D058847 |
| T29 | 1933-1940 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
| T32 | 2064-2071 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 447-451 | OrganismTaxon | denotes | mice |
| T2 | 604-608 | OrganismTaxon | denotes | mice |
| T3 | 1298-1302 | OrganismTaxon | denotes | mice |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T32 | 2064-2071 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T29 | 1933-1940 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T28 | 1860-1872 | ChemicalEntity | denotes | inflammasome | D058847 | |
| T25 | 1772-1779 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T22 | 1754-1761 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T21 | 1648-1651 | ChemicalEntity | denotes | HSL | http://purl.obolibrary.org/obo/CHEBI_17289 | |
| T20 | 1434-1441 | ChemicalEntity | denotes | Alcohol | http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T19 | 1304-1311 | ChemicalEntity | denotes | Alcohol | http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T16 | 1286-1293 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T13 | 944-951 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T10 | 626-633 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T8 | 566-575 | ChemicalEntity | denotes | rapamycin | http://purl.obolibrary.org/obo/CHEBI_9168|D020123 | |
| T5 | 435-442 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T2 | 215-222 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T1 | 50-57 | ChemicalEntity | denotes | Alcohol | http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T70956 | 2258-2262 | GeneOrGeneProduct | denotes | S6K1 | ||
| T74514 | 1898-1907 | GeneOrGeneProduct | denotes | caspase-1 | ||
| T27 | 1874-1879 | GeneOrGeneProduct | denotes | NLRP3 | ||
| T26 | 1854-1859 | GeneOrGeneProduct | denotes | NLRP3 | ||
| T40251 | 1807-1811 | GeneOrGeneProduct | denotes | IL-1 | ||
| T24 | 1797-1801 | GeneOrGeneProduct | denotes | IL-6 | ||
| T23 | 1720-1725 | GeneOrGeneProduct | denotes | C/EBP | ||
| T38192 | 1710-1714 | GeneOrGeneProduct | denotes | PPAR | ||
| T37744 | 1639-1643 | GeneOrGeneProduct | denotes | ATGL | ||
| T82209 | 1620-1637 | GeneOrGeneProduct | denotes | Lipolytic enzymes | ||
| T96370 | 1598-1602 | GeneOrGeneProduct | denotes | PARP | ||
| T18 | 1576-1585 | GeneOrGeneProduct | denotes | caspase-3 | ||
| T17 | 1481-1485 | GeneOrGeneProduct | denotes | ULK1 | ||
| T34184 | 1461-1465 | GeneOrGeneProduct | denotes | LC3B | ||
| T15 | 1452-1457 | GeneOrGeneProduct | denotes | Atg12 | ||
| T14 | 1363-1367 | GeneOrGeneProduct | denotes | eEF2 | ||
| T70328 | 1327-1332 | GeneOrGeneProduct | denotes | eEF2K | ||
| T12 | 1264-1269 | GeneOrGeneProduct | denotes | eIF4B | ||
| T11 | 1221-1225 | GeneOrGeneProduct | denotes | S6K1 | ||
| T37841 | 1145-1151 | GeneOrGeneProduct | denotes | PRAS40 | ||
| T9 | 1137-1140 | GeneOrGeneProduct | denotes | Akt | ||
| T21509 | 1129-1135 | GeneOrGeneProduct | denotes | 4E-BP1 | ||
| T7 | 1123-1127 | GeneOrGeneProduct | denotes | mTOR | ||
| T6 | 875-893 | GeneOrGeneProduct | denotes | controling protein | ||
| T86143 | 577-581 | GeneOrGeneProduct | denotes | mTOR | ||
| T4 | 546-575 | GeneOrGeneProduct | denotes | mammalian target of rapamycin | ||
| T3 | 254-259 | GeneOrGeneProduct | denotes | white | ||
| T7511 | 173-178 | GeneOrGeneProduct | denotes | White | ||
| T73879 | 103-107 | GeneOrGeneProduct | denotes | S6K1 | ||
| T53455 | 320-333 | DiseaseOrPhenotypicFeature | denotes | lipodystrophy | D008060 | |
| T7146 | 1298-1302 | OrganismTaxon | denotes | mice | ||
| T37678 | 604-608 | OrganismTaxon | denotes | mice | ||
| T97549 | 447-451 | OrganismTaxon | denotes | mice |