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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-90 Sentence denotes Effect of Rubus Occidentalis Extract on Metabolic Parameters in Subjects with Prediabetes:
T2 91-171 Sentence denotes A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial.
T3 172-258 Sentence denotes Rubus occidentalis (RO) has beneficial effects on glucose and lipid profiles in vitro.
T4 259-437 Sentence denotes The aim of the study was to investigate RO extract effect on metabolic parameters in prediabetic patients, adopting a 12-week, randomized, double-blind, placebo-controlled trial.
T5 438-630 Sentence denotes Forty-four patients (age 59.0 ± 8.2 years, 70.5% females, HbA1c 5.8 ± 0.4%) were divided into placebo (n = 13), low-dose RO extract (LRE; n = 14), or high-dose RO extract (HRE; n = 17) groups.
T6 631-699 Sentence denotes Either 900 or 1800 mg per day of RO extract was administered orally.
T7 700-913 Sentence denotes Area under the curve for glucose obtained 2 h after a 75-g oral glucose tolerance test was significantly decreased in the HRE group, compared with the placebo group (-28.1 ± 42.4 vs. +13.4 ± 52.6 mg/dL, p < 0.05).
T8 914-1058 Sentence denotes Homoeostasis model assessment-B was increased (+17.11 ± 10.69, +5.24 ± 4.10, and +0.86 ± 6.01 in HRE, LRE, and placebo, respectively, p < 0.05).
T9 1059-1428 Sentence denotes Serum levels of monocyte chemoattractant protein-1 and oxidized low-density lipoprotein were significantly decreased by treatment in a dose-dependent manner (monocyte chemoattractant protein-1: -35.0 ± 21.2, +8.4 ± 18.1, and +24.2 ± 14.5; oxidized low-density lipoprotein: -19.7 ± 8.5, -13.1 ± 7.2, and -2.2 ± 11.0 in the HRE, LRE, and placebo, respectively, p < 0.05).
T10 1429-1598 Sentence denotes The results support the beneficial effects of RO extract on the control of glycemia and vascular inflammation in prediabetic patients. (ClinicalTrials.gov: NCT01964703).
T11 1599-1639 Sentence denotes Copyright © 2016 John Wiley & Sons, Ltd.
T1 0-90 Sentence denotes Effect of Rubus Occidentalis Extract on Metabolic Parameters in Subjects with Prediabetes:
T2 91-171 Sentence denotes A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial.
T3 172-258 Sentence denotes Rubus occidentalis (RO) has beneficial effects on glucose and lipid profiles in vitro.
T4 259-437 Sentence denotes The aim of the study was to investigate RO extract effect on metabolic parameters in prediabetic patients, adopting a 12-week, randomized, double-blind, placebo-controlled trial.
T5 438-630 Sentence denotes Forty-four patients (age 59.0 ± 8.2 years, 70.5% females, HbA1c 5.8 ± 0.4%) were divided into placebo (n = 13), low-dose RO extract (LRE; n = 14), or high-dose RO extract (HRE; n = 17) groups.
T6 631-699 Sentence denotes Either 900 or 1800 mg per day of RO extract was administered orally.
T7 700-913 Sentence denotes Area under the curve for glucose obtained 2 h after a 75-g oral glucose tolerance test was significantly decreased in the HRE group, compared with the placebo group (-28.1 ± 42.4 vs. +13.4 ± 52.6 mg/dL, p < 0.05).
T8 914-1058 Sentence denotes Homoeostasis model assessment-B was increased (+17.11 ± 10.69, +5.24 ± 4.10, and +0.86 ± 6.01 in HRE, LRE, and placebo, respectively, p < 0.05).
T9 1059-1428 Sentence denotes Serum levels of monocyte chemoattractant protein-1 and oxidized low-density lipoprotein were significantly decreased by treatment in a dose-dependent manner (monocyte chemoattractant protein-1: -35.0 ± 21.2, +8.4 ± 18.1, and +24.2 ± 14.5; oxidized low-density lipoprotein: -19.7 ± 8.5, -13.1 ± 7.2, and -2.2 ± 11.0 in the HRE, LRE, and placebo, respectively, p < 0.05).
T10 1429-1598 Sentence denotes The results support the beneficial effects of RO extract on the control of glycemia and vascular inflammation in prediabetic patients. (ClinicalTrials.gov: NCT01964703).
T11 1599-1639 Sentence denotes Copyright © 2016 John Wiley & Sons, Ltd.

maxiaofeng52_800_3

Id Subject Object Predicate Lexical cue
T1 10-28 CI denotes Rubus Occidentalis
T10 412-419 CI denotes placebo
T11 851-858 CI denotes placebo
T12 1025-1032 CI denotes placebo
T13 1395-1402 CI denotes placebo
T14 78-89 DP denotes Prediabetes
T15 344-355 DP denotes prediabetic
T16 1542-1553 DP denotes prediabetic
T2 172-190 CI denotes Rubus occidentalis
T3 192-194 CI denotes RO
T4 299-301 CI denotes RO
T5 559-561 CI denotes RO
T6 598-600 CI denotes RO
T7 664-666 CI denotes RO
T8 1475-1477 CI denotes RO
T9 532-539 CI denotes placebo
T17 137-144 CI denotes Placebo

wangzhuo19_800_3

Id Subject Object Predicate Lexical cue
T1 10-28 CI denotes Rubus Occidentalis
T2 172-190 CI denotes Rubus occidentalis
T3 192-194 CI denotes RO
T4 299-301 CI denotes RO
T5 559-561 CI denotes RO
T6 598-600 CI denotes RO
T7 664-666 CI denotes RO
T8 1475-1477 CI denotes RO
T9 532-539 CI denotes placebo
T10 412-419 CI denotes placebo
T11 851-858 CI denotes placebo
T12 1025-1032 CI denotes placebo
T13 1395-1402 CI denotes placebo
T14 137-144 CI denotes Placebo
T15 78-89 DP denotes Prediabetes
T16 344-355 DP denotes prediabetic
T17 1542-1553 DP denotes prediabetic