PubMed:27251373
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 98-113 | Cell | denotes | Dendritic Cells | http://purl.obolibrary.org/obo/CL:0000451|http://purl.obolibrary.org/obo/CL:0001056 |
| T3 | 407-413 | Cell | denotes | T cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T4 | 607-631 | Cell | denotes | CD4(+) and CD8(+) T cell | http://purl.obolibrary.org/obo/CL:0002489 |
| T5 | 625-631 | Cell | denotes | T cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T6 | 780-795 | Cell | denotes | dendritic cells | http://purl.obolibrary.org/obo/CL:0000451|http://purl.obolibrary.org/obo/CL:0001056 |
| T8 | 797-800 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T9 | 873-876 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T10 | 922-925 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T11 | 1028-1035 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T12 | 1066-1073 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T13 | 1193-1196 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T14 | 1262-1265 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T15 | 1317-1323 | Cell | denotes | T cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T16 | 1428-1435 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 208-218 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 72-81 | Glycan | denotes | I Antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G56045WU |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 72-81 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | I Antigen | http://www.glycoepitope.jp/epitopes/EP0138 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 208-218 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 227-237 | OrganismTaxon | denotes | Leishmania | 38568|5658 |
| T3 | 1105-1109 | OrganismTaxon | denotes | mice | 10088 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 98-113 | Cell | denotes | Dendritic Cells | http://purl.obolibrary.org/obo/CL:0000451|http://purl.obolibrary.org/obo/CL:0001056 |
| T3 | 407-413 | Cell | denotes | T cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T4 | 607-631 | Cell | denotes | CD4(+) and CD8(+) T cell | http://purl.obolibrary.org/obo/CL:0002489 |
| T5 | 625-631 | Cell | denotes | T cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T6 | 780-795 | Cell | denotes | dendritic cells | http://purl.obolibrary.org/obo/CL:0000451|http://purl.obolibrary.org/obo/CL:0001056 |
| T8 | 797-800 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T9 | 873-876 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T10 | 922-925 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T11 | 1028-1035 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T12 | 1066-1073 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T13 | 1193-1196 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T14 | 1262-1265 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T15 | 1317-1323 | Cell | denotes | T cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T16 | 1428-1435 | Cell | denotes | T cells | http://purl.obolibrary.org/obo/CL:0000084 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 98-113 | Body_part | denotes | Dendritic Cells | http://purl.obolibrary.org/obo/CL_0000451 |
| T2 | 194-207 | Body_part | denotes | intracellular | http://purl.obolibrary.org/obo/GO_0005622 |
| T3 | 407-413 | Body_part | denotes | T cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T4 | 625-631 | Body_part | denotes | T cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T5 | 780-795 | Body_part | denotes | dendritic cells | http://purl.obolibrary.org/obo/CL_0000451 |
| T6 | 797-800 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T7 | 873-876 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T8 | 922-925 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T9 | 1193-1196 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T10 | 1262-1265 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T11 | 1317-1323 | Body_part | denotes | T cell | http://purl.obolibrary.org/obo/CL_0000084 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-142 | Sentence | denotes | A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells. |
| T2 | 143-273 | Sentence | denotes | The most effective strategy for protection against intracellular infections such as Leishmania is vaccination with live parasites. |
| T3 | 274-349 | Sentence | denotes | Use of recombinant proteins avoids the risks associated with live vaccines. |
| T4 | 350-487 | Sentence | denotes | However, due to low immunogenicity, they fail to trigger T cell responses particularly of CD8(+) cells requisite for persistent immunity. |
| T5 | 488-667 | Sentence | denotes | Previously we showed the importance of protein entrapment in cationic liposomes and MPL as adjuvant for elicitation of CD4(+) and CD8(+) T cell responses for long-term protection. |
| T6 | 668-802 | Sentence | denotes | In this study we investigated the role of cationic liposomes on maturation and antigen presentation capacity of dendritic cells (DCs). |
| T7 | 803-921 | Sentence | denotes | We observed that cationic liposomes were taken up very efficiently by DCs and transported to different cellular sites. |
| T8 | 922-1036 | Sentence | denotes | DCs activated with liposomal rgp63 led to efficient presentation of antigen to specific CD4(+) and CD8(+) T cells. |
| T9 | 1037-1197 | Sentence | denotes | Furthermore, lymphoid CD8(+) T cells from liposomal rgp63 immunized mice demonstrated better proliferative ability when co-cultured ex vivo with stimulated DCs. |
| T10 | 1198-1378 | Sentence | denotes | Addition of MPL to vaccine enhanced the antigen presentation by DCs and induced more efficient antigen specific CD8(+) T cell responses when compared to free and liposomal antigen. |
| T11 | 1379-1523 | Sentence | denotes | These liposomal formulations presented to CD8(+) T cells through TAP-dependent MHC-I pathway offer new possibilities for a safe subunit vaccine. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 72-81 | Glycan | denotes | I Antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G56045WU |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 72-81 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | I Antigen | http://www.glycoepitope.jp/epitopes/EP0138 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 227-237 | OrganismTaxon | denotes | Leishmania | 38568|5658 |
| T3 | 1105-1109 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 98-113 | Body_part | denotes | Dendritic Cells | http://purl.obolibrary.org/obo/CL_0000451 |
| T2 | 194-207 | Body_part | denotes | intracellular | http://purl.obolibrary.org/obo/GO_0005622 |
| T3 | 407-413 | Body_part | denotes | T cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T4 | 625-631 | Body_part | denotes | T cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T5 | 780-795 | Body_part | denotes | dendritic cells | http://purl.obolibrary.org/obo/CL_0000451 |
| T6 | 797-800 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T7 | 873-876 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T8 | 922-925 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T9 | 1193-1196 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T10 | 1262-1265 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T11 | 1317-1323 | Body_part | denotes | T cell | http://purl.obolibrary.org/obo/CL_0000084 |