| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-122 |
Sentence |
denotes |
Heart Disease, Hypertension, Gestational Diabetes Mellitus, and Preeclampsia/Eclampsia in Mothers With Juvenile Arthritis: |
| TextSentencer_T2 |
123-151 |
Sentence |
denotes |
A Nested Case-Control Study. |
| TextSentencer_T3 |
152-162 |
Sentence |
denotes |
OBJECTIVE: |
| TextSentencer_T4 |
163-408 |
Sentence |
denotes |
To determine whether women with a history of juvenile arthritis are at higher risk for heart disease and hypertension and for developing adverse maternal outcomes: gestational diabetes mellitus, maternal hypertension, and preeclampsia/eclampsia. |
| TextSentencer_T5 |
409-417 |
Sentence |
denotes |
METHODS: |
| TextSentencer_T6 |
418-618 |
Sentence |
denotes |
We designed a nested case-control study from a cohort of first-time mothers with prior physician billing codes suggesting juvenile arthritis, and a matched comparison group without juvenile arthritis. |
| TextSentencer_T7 |
619-884 |
Sentence |
denotes |
For the nested case-control design, we selected 3 controls for each case for the outcomes of heart disease (n = 403), prepregnancy hypertension (n = 66), gestational diabetes mellitus (n = 285), maternal hypertension (n = 561), and preeclampsia/eclampsia (n = 236). |
| TextSentencer_T8 |
885-967 |
Sentence |
denotes |
We used conditional logistic regression, adjusting for maternal age and education. |
| TextSentencer_T9 |
968-976 |
Sentence |
denotes |
RESULTS: |
| TextSentencer_T10 |
977-1189 |
Sentence |
denotes |
Having juvenile arthritis was associated with heart disease (odds ratio [OR] 2.44 [95% confidence interval (95% CI) 1.15-5.15]) but not with gestational hypertension, diabetes mellitus, or preeclampsia/eclampsia. |
| TextSentencer_T11 |
1190-1255 |
Sentence |
denotes |
All 66 cases of prepregnancy hypertension had juvenile arthritis. |
| TextSentencer_T12 |
1256-1371 |
Sentence |
denotes |
Having prepregnancy hypertension was strongly associated with preeclampsia/eclampsia (OR 8.05 [95% CI 2.69-24.07]). |
| TextSentencer_T13 |
1372-1383 |
Sentence |
denotes |
CONCLUSION: |
| TextSentencer_T14 |
1384-1462 |
Sentence |
denotes |
Women with a history of juvenile arthritis had a higher risk of heart disease. |
| TextSentencer_T15 |
1463-1561 |
Sentence |
denotes |
This risk signals the potential importance of cardiac prevention strategies in juvenile arthritis. |
| TextSentencer_T16 |
1562-1668 |
Sentence |
denotes |
As this was a retrospective study, it was not possible to correct for some relevant potential confounders. |
| TextSentencer_T17 |
1669-1820 |
Sentence |
denotes |
Further studies should assess the impact of medications, disease severity, and other factors (e.g., obesity) on cardiac outcomes in juvenile arthritis. |
| T1 |
0-122 |
Sentence |
denotes |
Heart Disease, Hypertension, Gestational Diabetes Mellitus, and Preeclampsia/Eclampsia in Mothers With Juvenile Arthritis: |
| T2 |
123-151 |
Sentence |
denotes |
A Nested Case-Control Study. |
| T3 |
152-162 |
Sentence |
denotes |
OBJECTIVE: |
| T4 |
163-408 |
Sentence |
denotes |
To determine whether women with a history of juvenile arthritis are at higher risk for heart disease and hypertension and for developing adverse maternal outcomes: gestational diabetes mellitus, maternal hypertension, and preeclampsia/eclampsia. |
| T5 |
409-417 |
Sentence |
denotes |
METHODS: |
| T6 |
418-618 |
Sentence |
denotes |
We designed a nested case-control study from a cohort of first-time mothers with prior physician billing codes suggesting juvenile arthritis, and a matched comparison group without juvenile arthritis. |
| T7 |
619-884 |
Sentence |
denotes |
For the nested case-control design, we selected 3 controls for each case for the outcomes of heart disease (n = 403), prepregnancy hypertension (n = 66), gestational diabetes mellitus (n = 285), maternal hypertension (n = 561), and preeclampsia/eclampsia (n = 236). |
| T8 |
885-967 |
Sentence |
denotes |
We used conditional logistic regression, adjusting for maternal age and education. |
| T9 |
968-976 |
Sentence |
denotes |
RESULTS: |
| T10 |
977-1189 |
Sentence |
denotes |
Having juvenile arthritis was associated with heart disease (odds ratio [OR] 2.44 [95% confidence interval (95% CI) 1.15-5.15]) but not with gestational hypertension, diabetes mellitus, or preeclampsia/eclampsia. |
| T11 |
1190-1255 |
Sentence |
denotes |
All 66 cases of prepregnancy hypertension had juvenile arthritis. |
| T12 |
1256-1371 |
Sentence |
denotes |
Having prepregnancy hypertension was strongly associated with preeclampsia/eclampsia (OR 8.05 [95% CI 2.69-24.07]). |
| T13 |
1372-1383 |
Sentence |
denotes |
CONCLUSION: |
| T14 |
1384-1462 |
Sentence |
denotes |
Women with a history of juvenile arthritis had a higher risk of heart disease. |
| T15 |
1463-1561 |
Sentence |
denotes |
This risk signals the potential importance of cardiac prevention strategies in juvenile arthritis. |
| T16 |
1562-1668 |
Sentence |
denotes |
As this was a retrospective study, it was not possible to correct for some relevant potential confounders. |
| T17 |
1669-1820 |
Sentence |
denotes |
Further studies should assess the impact of medications, disease severity, and other factors (e.g., obesity) on cardiac outcomes in juvenile arthritis. |
