| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-98 |
Sentence |
denotes |
Isolated gestational proteinuria preceding the diagnosis of preeclampsia - an observational study. |
| TextSentencer_T2 |
99-112 |
Sentence |
denotes |
INTRODUCTION: |
| TextSentencer_T3 |
113-196 |
Sentence |
denotes |
Some pregnant women develop significant proteinuria in the absence of hypertension. |
| TextSentencer_T4 |
197-293 |
Sentence |
denotes |
However, clinical significance of isolated gestational proteinuria (IGP) is not well understood. |
| TextSentencer_T5 |
294-476 |
Sentence |
denotes |
This study aimed to determine the prevalence of IGP in singleton pregnancies and the proportion of women with IGP who subsequently developed preeclampsia (IGP-PE) among all PE cases. |
| TextSentencer_T6 |
477-498 |
Sentence |
denotes |
MATERIAL AND METHODS: |
| TextSentencer_T7 |
499-678 |
Sentence |
denotes |
This was an observational study of 6819 women with singleton pregnancies at 12 centers, including 938 women with at least once determination of protein-to-creatinine ratio (P/Cr). |
| TextSentencer_T8 |
679-763 |
Sentence |
denotes |
Significant proteinuria in pregnancy (SPIP) was defined as P/Cr (mg/mg) level >0.27. |
| TextSentencer_T9 |
764-819 |
Sentence |
denotes |
IGP was defined as SPIP in the absence of hypertension. |
| TextSentencer_T10 |
820-940 |
Sentence |
denotes |
Gestational hypertension (GH) preceding preeclampsia (GH-PE) was defined as preeclampsia (PE) in which GH preceded SPIP. |
| TextSentencer_T11 |
941-1042 |
Sentence |
denotes |
Simultaneous PE (S-PE) was defined as PE in which both SPIP and hypertension occurred simultaneously. |
| TextSentencer_T12 |
1043-1135 |
Sentence |
denotes |
RESULTS: IGP and PE were diagnosed in 130 (1.9%) and 158 (2.3%) of 6819 women, respectively. |
| TextSentencer_T13 |
1136-1228 |
Sentence |
denotes |
Of 130 women with IGP, 32 (25%) progressed to PE and accounted for 20% of all women with PE. |
| TextSentencer_T14 |
1229-1383 |
Sentence |
denotes |
Hence, women with IGP had a relative risk of 13.1 (95% CI; 9.2-18.5) for developing PE compared with those without IGP [25% (32/130) vs. 1.9% (126/6689)]. |
| TextSentencer_T15 |
1384-1550 |
Sentence |
denotes |
At diagnosis of SPIP, P/Cr levels already exceeded 1.0 more often in women with S-PE than in those with IGP-PE [67% (33/49) vs. 44% (14/32), respectively, p = 0.031]. |
| TextSentencer_T16 |
1551-1659 |
Sentence |
denotes |
CONCLUSIONS: IGP is a risk factor for PE, and IGP-PE accounts for a considerable proportion (20%) of all PE. |
| T1 |
0-98 |
Sentence |
denotes |
Isolated gestational proteinuria preceding the diagnosis of preeclampsia - an observational study. |
| T2 |
99-112 |
Sentence |
denotes |
INTRODUCTION: |
| T3 |
113-196 |
Sentence |
denotes |
Some pregnant women develop significant proteinuria in the absence of hypertension. |
| T4 |
197-293 |
Sentence |
denotes |
However, clinical significance of isolated gestational proteinuria (IGP) is not well understood. |
| T5 |
294-476 |
Sentence |
denotes |
This study aimed to determine the prevalence of IGP in singleton pregnancies and the proportion of women with IGP who subsequently developed preeclampsia (IGP-PE) among all PE cases. |
| T6 |
477-498 |
Sentence |
denotes |
MATERIAL AND METHODS: |
| T7 |
499-678 |
Sentence |
denotes |
This was an observational study of 6819 women with singleton pregnancies at 12 centers, including 938 women with at least once determination of protein-to-creatinine ratio (P/Cr). |
| T8 |
679-763 |
Sentence |
denotes |
Significant proteinuria in pregnancy (SPIP) was defined as P/Cr (mg/mg) level >0.27. |
| T9 |
764-819 |
Sentence |
denotes |
IGP was defined as SPIP in the absence of hypertension. |
| T10 |
820-940 |
Sentence |
denotes |
Gestational hypertension (GH) preceding preeclampsia (GH-PE) was defined as preeclampsia (PE) in which GH preceded SPIP. |
| T11 |
941-1042 |
Sentence |
denotes |
Simultaneous PE (S-PE) was defined as PE in which both SPIP and hypertension occurred simultaneously. |
| T12 |
1043-1135 |
Sentence |
denotes |
RESULTS: IGP and PE were diagnosed in 130 (1.9%) and 158 (2.3%) of 6819 women, respectively. |
| T13 |
1136-1228 |
Sentence |
denotes |
Of 130 women with IGP, 32 (25%) progressed to PE and accounted for 20% of all women with PE. |
| T14 |
1229-1383 |
Sentence |
denotes |
Hence, women with IGP had a relative risk of 13.1 (95% CI; 9.2-18.5) for developing PE compared with those without IGP [25% (32/130) vs. 1.9% (126/6689)]. |
| T15 |
1384-1550 |
Sentence |
denotes |
At diagnosis of SPIP, P/Cr levels already exceeded 1.0 more often in women with S-PE than in those with IGP-PE [67% (33/49) vs. 44% (14/32), respectively, p = 0.031]. |
| T16 |
1551-1659 |
Sentence |
denotes |
CONCLUSIONS: IGP is a risk factor for PE, and IGP-PE accounts for a considerable proportion (20%) of all PE. |