
PubMed:27052160
Annnotations
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-73 | Sentence | denotes | Alteration of podocyte phenotype in the urine of women with preeclampsia. |
TextSentencer_T2 | 74-252 | Sentence | denotes | Podocyte injury has been suggested to induce phenotypic alteration of glomerular podocytes and accelerate the detachment of podocytes from the glomeruli resulting in podocyturia. |
TextSentencer_T3 | 253-369 | Sentence | denotes | However, it is not clear whether podocyte phenotypic alteration occurs in the urine of women with preeclampsia (PE). |
TextSentencer_T4 | 370-647 | Sentence | denotes | Seventy-seven and 116 pelleted urine samples from 38 and 18 women at various stages of normal and PE pregnancies, respectively underwent quantitative analysis of podocyte-specific or associated protein mRNA expression, including podocin, nephrin, and synaptopodin using RT-PCR. |
TextSentencer_T5 | 648-777 | Sentence | denotes | Significant proteinuria in pregnancy (SPIP) is defined as protein:creatinine ratio (P/Cr, mg/mg) ≥ 0.27 in the urine supernatant. |
TextSentencer_T6 | 778-939 | Sentence | denotes | All three urine-pellet mRNAs expression levels were significantly positively correlated with P/Cr levels, suggesting that podocyturia increased with proteinuria. |
TextSentencer_T7 | 940-1274 | Sentence | denotes | The podocin:nephrin mRNA ratio (PNR) and synaptopodin:nephrin mRNA ratio (SNR) increased significantly with increasing P/Cr, while the podocin:synaptopodin mRNA ratio (PSR) did not change significantly according to P/Cr, resulting in significantly higher PNR and SNR, but not PSR levels, in urine from PE women with than without SPIP. |
TextSentencer_T8 | 1275-1380 | Sentence | denotes | The PNR, SNR, and PSR in urine from PE women before onset of SPIP were comparable to those from controls. |
TextSentencer_T9 | 1381-1464 | Sentence | denotes | Thus, nephrin mRNA expression was reduced in the podocytes recovered from PE women. |
T1 | 0-73 | Sentence | denotes | Alteration of podocyte phenotype in the urine of women with preeclampsia. |
T2 | 74-252 | Sentence | denotes | Podocyte injury has been suggested to induce phenotypic alteration of glomerular podocytes and accelerate the detachment of podocytes from the glomeruli resulting in podocyturia. |
T3 | 253-369 | Sentence | denotes | However, it is not clear whether podocyte phenotypic alteration occurs in the urine of women with preeclampsia (PE). |
T4 | 370-647 | Sentence | denotes | Seventy-seven and 116 pelleted urine samples from 38 and 18 women at various stages of normal and PE pregnancies, respectively underwent quantitative analysis of podocyte-specific or associated protein mRNA expression, including podocin, nephrin, and synaptopodin using RT-PCR. |
T5 | 648-777 | Sentence | denotes | Significant proteinuria in pregnancy (SPIP) is defined as protein:creatinine ratio (P/Cr, mg/mg) ≥ 0.27 in the urine supernatant. |
T6 | 778-939 | Sentence | denotes | All three urine-pellet mRNAs expression levels were significantly positively correlated with P/Cr levels, suggesting that podocyturia increased with proteinuria. |
T7 | 940-1274 | Sentence | denotes | The podocin:nephrin mRNA ratio (PNR) and synaptopodin:nephrin mRNA ratio (SNR) increased significantly with increasing P/Cr, while the podocin:synaptopodin mRNA ratio (PSR) did not change significantly according to P/Cr, resulting in significantly higher PNR and SNR, but not PSR levels, in urine from PE women with than without SPIP. |
T8 | 1275-1380 | Sentence | denotes | The PNR, SNR, and PSR in urine from PE women before onset of SPIP were comparable to those from controls. |
T9 | 1381-1464 | Sentence | denotes | Thus, nephrin mRNA expression was reduced in the podocytes recovered from PE women. |
Preeclampsia
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-Preeclampsia-B_T1 | 60-72 | ORPHA:275555 | denotes | preeclampsia |
PD-Preeclampsia-B_T2 | 351-363 | ORPHA:275555 | denotes | preeclampsia |
Preeclampsia-compare
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-Preeclampsia-B_T1 | 60-72 | ORPHA:275555 | denotes | preeclampsia |
PD-Preeclampsia-B_T2 | 351-363 | ORPHA:275555 | denotes | preeclampsia |
preeclampsia_genes
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-PreeclampsiaGenes-B_T1 | 621-633 | HGNC:SYNPO | denotes | synaptopodin |
PD-PreeclampsiaGenes-B_T2 | 621-633 | HGNC:SYNPO2 | denotes | synaptopodin |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-UBERON-AE-B_T1 | 40-45 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T2 | 331-336 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T3 | 401-406 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T4 | 759-764 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T5 | 788-793 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T6 | 1231-1236 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T7 | 1300-1305 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
performance-test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-UBERON-AE-B_T1 | 40-45 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T2 | 331-336 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T3 | 401-406 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T4 | 759-764 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T5 | 788-793 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T6 | 1231-1236 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
PD-UBERON-AE-B_T7 | 1300-1305 | http://purl.obolibrary.org/obo/UBERON_0001088 | denotes | urine |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 60-72 | Disease | denotes | preeclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
T2 | 83-89 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T3 | 351-363 | Disease | denotes | preeclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
T4 | 365-367 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
T5 | 468-470 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
T6 | 660-671 | Disease | denotes | proteinuria | http://purl.obolibrary.org/obo/MONDO_0003634 |
T7 | 927-938 | Disease | denotes | proteinuria | http://purl.obolibrary.org/obo/MONDO_0003634 |
T8 | 1242-1244 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
T9 | 1311-1313 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
T10 | 1455-1457 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 40-45 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T2 | 331-336 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T3 | 401-406 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T4 | 759-764 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T5 | 788-793 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T6 | 1231-1236 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T7 | 1300-1305 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 14-22 | Body_part | denotes | podocyte | http://purl.obolibrary.org/obo/CL_0000653 |
T2 | 40-45 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T3 | 74-82 | Body_part | denotes | Podocyte | http://purl.obolibrary.org/obo/CL_0000653 |
T4 | 144-164 | Body_part | denotes | glomerular podocytes | http://purl.obolibrary.org/obo/CL_0000653 |
T5 | 198-207 | Body_part | denotes | podocytes | http://purl.obolibrary.org/obo/CL_0000653 |
T6 | 286-294 | Body_part | denotes | podocyte | http://purl.obolibrary.org/obo/CL_0000653 |
T7 | 331-336 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T8 | 401-406 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T9 | 532-540 | Body_part | denotes | podocyte | http://purl.obolibrary.org/obo/CL_0000653 |
T10 | 759-764 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T11 | 788-793 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T12 | 794-800 | Body_part | denotes | pellet | http://purl.obolibrary.org/obo/UBERON_0036018 |
T13 | 1231-1236 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T14 | 1300-1305 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T15 | 1430-1439 | Body_part | denotes | podocytes | http://purl.obolibrary.org/obo/CL_0000653 |
HP-phenotype
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 660-671 | Phenotype | denotes | proteinuria | HP:0000093 |
T2 | 927-938 | Phenotype | denotes | proteinuria | HP:0000093 |
CL-cell
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 14-22 | Cell | denotes | podocyte | http://purl.obolibrary.org/obo/CL:0000653 |
T2 | 74-82 | Cell | denotes | Podocyte | http://purl.obolibrary.org/obo/CL:0000653 |
T3 | 144-164 | Cell | denotes | glomerular podocytes | http://purl.obolibrary.org/obo/CL:0000653 |
T4 | 198-207 | Cell | denotes | podocytes | http://purl.obolibrary.org/obo/CL:0000653 |
T5 | 286-294 | Cell | denotes | podocyte | http://purl.obolibrary.org/obo/CL:0000653 |
T6 | 532-540 | Cell | denotes | podocyte | http://purl.obolibrary.org/obo/CL:0000653 |
T7 | 1430-1439 | Cell | denotes | podocytes | http://purl.obolibrary.org/obo/CL:0000653 |