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PubMed:26994106 JSONTXT

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c_corpus

Id Subject Object Predicate Lexical cue
T1 51-57 UBERON:0000310 denotes breast
T2 51-64 D001943 denotes breast cancer
T3 51-64 D001943 denotes breast cancer
T4 80-85 10090 denotes mouse
T5 80-85 D051379 denotes mouse
T6 86-99 UBERON:0001911 denotes mammary gland
T7 86-99 UBERON:0005200 denotes mammary gland
T9 265-280 D051379 denotes laboratory mice
T10 276-280 PR:000005054 denotes mice
T12 276-280 O89094 denotes mice
T14 331-337 UBERON:0000310 denotes breast
T15 331-344 D001943 denotes breast cancer
T16 331-344 D001943 denotes breast cancer
T19 361-364 SO:0002045 denotes pre
T18 361-364 PR:Q8LLD0 denotes pre
T20 361-364 UBERON:0001782 denotes pre
T17 361-364 GO:0003904 denotes pre
T21 418-423 UBERON:0000180 denotes flank
T22 480-486 UBERON:0000310 denotes breast
T23 480-493 D001943 denotes breast cancer
T24 480-493 D001943 denotes breast cancer
T25 564-570 D009369 denotes tumors
T26 564-570 D009369 denotes tumors
T27 580-585 10090 denotes mouse
T28 580-585 D051379 denotes mouse
T29 586-599 UBERON:0001911 denotes mammary gland
T30 586-599 UBERON:0005200 denotes mammary gland
T32 623-629 UBERON:0000310 denotes breast
T33 630-637 D009369 denotes cancers
T34 630-637 D009369 denotes cancers
T35 786-791 10090 denotes mouse
T36 786-791 D051379 denotes mouse
T37 792-805 UBERON:0001911 denotes mammary gland
T38 792-805 UBERON:0005200 denotes mammary gland
T40 854-858 PR:000005054 denotes mice
T42 854-858 O89094 denotes mice
T41 854-858 D051379 denotes mice
T43 854-858 10095 denotes mice
T44 978-995 UBERON:0001179 denotes peritoneal cavity
T46 1025-1031 UBERON:3010325 denotes animal
T47 1025-1031 UBERON:0000468 denotes animal
T48 1206-1219 UBERON:0001911 denotes mammary gland
T49 1206-1219 UBERON:0005200 denotes mammary gland
T51 1278-1284 UBERON:3010325 denotes animal
T52 1278-1284 UBERON:0000468 denotes animal

UseCases_ArguminSci_Discourse

Id Subject Object Predicate Lexical cue
T1 0-100 DRI_Background denotes A less invasive method for orthotopic injection of breast cancer cells into the mouse mammary gland.
T2 101-253 DRI_Background denotes Breast cancer is the most common type of cancer diagnosed in women, and the second most common cause of cancer-related deaths in women in North America.
T3 254-398 DRI_Background denotes The use of laboratory mice in research is an essential tool for the study of breast cancer biology and for pre-clinical therapeutic development.
T4 399-536 DRI_Background denotes While subcutaneous flank injections of cancer cells are widely used for studying breast cancer biology and for exploring novel therapies,
T5 537-560 Token_Label.OUTSIDE denotes orthotopic xenografting
T6 561-682 DRI_Background denotes of tumors into the mouse mammary gland allow for the study of breast cancers in a biologically relevant microenvironment.
T7 683-921 DRI_Approach denotes In this study we report a modification of the method of orthotopic injections of cancer cells into the mouse mammary gland which greatly reduces the effects of surgery in mice including decreased wound size, procedure time and anesthesia.
T8 922-996 DRI_Background denotes It also removes the risk of accidentally puncturing the peritoneal cavity.
T9 997-1078 DRI_Background denotes Consequently post-operative animal handling and stress are significantly reduced.
T10 1079-1159 DRI_Outcome denotes All of these advantages are present without compromising procedure success rate.
T11 1160-1293 DRI_Outcome denotes Therefore, this modification makes orthotopic mammary gland injection a more efficient procedure and greatly improves animal welfare.