
PubMed:26991973
Annnotations
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
11139 | 0-4 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11140 | 44-55 | OrganismTaxon | denotes | Arabidopsis | NCBITaxon:3702 |
11141 | 276-287 | GeneOrGeneProduct | denotes | CLE peptide | NCBIGene:820713|NCBIGene:821957|NCBIGene:832170 |
11142 | 292-332 | GeneOrGeneProduct | denotes | leucine-rich repeat receptor-like kinase | NCBIGene:835209|NCBIGene:836269 |
11143 | 334-341 | GeneOrGeneProduct | denotes | LRR-RLK | NCBIGene:835209|NCBIGene:836269 |
11144 | 505-512 | GeneOrGeneProduct | denotes | LRR-RLK | NCBIGene:835209|NCBIGene:836269 |
11145 | 513-517 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11146 | 558-578 | OrganismTaxon | denotes | Arabidopsis thaliana | NCBITaxon:3702 |
11147 | 633-637 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11148 | 718-723 | GeneOrGeneProduct | denotes | CLE41 | NCBIGene:822075 |
11149 | 724-727 | GeneOrGeneProduct | denotes | PXY | NCBIGene:836269 |
11150 | 774-778 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11151 | 813-818 | GeneOrGeneProduct | denotes | CLE41 | NCBIGene:822075 |
11152 | 819-822 | GeneOrGeneProduct | denotes | PXY | NCBIGene:836269 |
11153 | 871-875 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11154 | 964-968 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11155 | 973-976 | GeneOrGeneProduct | denotes | PXY | NCBIGene:836269 |
11156 | 983-991 | GeneOrGeneProduct | denotes | LRR-RLKs | NCBIGene:835209|NCBIGene:836269 |
11157 | 1088-1092 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11158 | 1101-1104 | GeneOrGeneProduct | denotes | PXY | NCBIGene:836269 |
11159 | 1123-1127 | GeneOrGeneProduct | denotes | CLV1 | NCBIGene:843915 |
11160 | 1207-1211 | GeneOrGeneProduct | denotes | mol1 | NCBIGene:835209 |
11161 | 1241-1245 | GeneOrGeneProduct | denotes | MOL1 | NCBIGene:835209 |
11162 | 1293-1301 | ChemicalEntity | denotes | ethylene | MESH:D005030 |
11163 | 1306-1319 | ChemicalEntity | denotes | jasmonic acid | MESH:C011006 |
11164 | 1408-1419 | OrganismTaxon | denotes | Arabidopsis | NCBITaxon:3702 |
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-56 | Sentence | denotes | MOL1 is required for cambium homeostasis in Arabidopsis. |
T2 | 57-167 | Sentence | denotes | Plants maintain pools of pluripotent stem cells which allow them to constantly produce new tissues and organs. |
T3 | 168-352 | Sentence | denotes | Stem cell homeostasis in shoot and root tips depends on negative regulation by ligand-receptor pairs of the CLE peptide and leucine-rich repeat receptor-like kinase (LRR-RLK) families. |
T4 | 353-482 | Sentence | denotes | However, regulation of the cambium, the stem cell niche required for lateral growth of shoots and roots, is poorly characterized. |
T5 | 483-579 | Sentence | denotes | Here we show that the LRR-RLK MOL1 is necessary for cambium homeostasis in Arabidopsis thaliana. |
T6 | 580-745 | Sentence | denotes | By employing promoter reporter lines, we reveal that MOL1 is active in a domain that is distinct from the domain of the positively acting CLE41/PXY signaling module. |
T7 | 746-933 | Sentence | denotes | In particular, we show that MOL1 acts in an opposing manner to the CLE41/PXY module and that changing the domain or level of MOL1 expression both result in disturbed cambium organization. |
T8 | 934-1074 | Sentence | denotes | Underlining discrete roles of MOL1 and PXY, both LRR-RLKs are not able to replace each other when their expression domains are interchanged. |
T9 | 1075-1168 | Sentence | denotes | Furthermore, MOL1 but not PXY is able to rescue CLV1 deficiency in the shoot apical meristem. |
T10 | 1169-1425 | Sentence | denotes | By identifying genes mis-expressed in mol1 mutants, we demonstrate that MOL1 represses genes associated with stress-related ethylene and jasmonic acid hormone signaling pathways which have known roles in coordinating lateral growth of the Arabidopsis stem. |
T11 | 1426-1712 | Sentence | denotes | Our findings provide evidence that common regulatory mechanisms in different plant stem cell niches are adapted to specific niche anatomies and emphasize the importance of a complex spatial organization of intercellular signaling cascades for a strictly bidirectional tissue production. |
LitCoin-entities-OrganismTaxon-PD
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 44-55 | OrganismTaxon | denotes | Arabidopsis | NCBItxid:3701 |
T2 | 57-63 | OrganismTaxon | denotes | Plants | NCBItxid:3193 |
T3 | 203-207 | OrganismTaxon | denotes | root | NCBItxid:1 |
T4 | 558-578 | OrganismTaxon | denotes | Arabidopsis thaliana | NCBItxid:3702 |
T5 | 1408-1419 | OrganismTaxon | denotes | Arabidopsis | NCBItxid:3701 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-4 | GeneOrGeneProduct | denotes | MOL1 |
T2 | 57-63 | GeneOrGeneProduct | denotes | Plants |
T3 | 99-104 | GeneOrGeneProduct | denotes | cells |
T4 | 117-121 | GeneOrGeneProduct | denotes | them |
T5 | 173-177 | GeneOrGeneProduct | denotes | cell |
T6 | 203-207 | GeneOrGeneProduct | denotes | root |
T7 | 233-243 | GeneOrGeneProduct | denotes | regulation |
T8 | 254-262 | GeneOrGeneProduct | denotes | receptor |
T9 | 263-268 | GeneOrGeneProduct | denotes | pairs |
T10 | 292-332 | GeneOrGeneProduct | denotes | leucine-rich repeat receptor-like kinase |
T11 | 334-341 | GeneOrGeneProduct | denotes | LRR-RLK |
T12 | 362-372 | GeneOrGeneProduct | denotes | regulation |
T13 | 398-402 | GeneOrGeneProduct | denotes | cell |
T14 | 422-429 | GeneOrGeneProduct | denotes | lateral |
T15 | 430-436 | GeneOrGeneProduct | denotes | growth |
T16 | 451-456 | GeneOrGeneProduct | denotes | roots |
T17 | 505-512 | GeneOrGeneProduct | denotes | LRR-RLK |
T18 | 513-517 | GeneOrGeneProduct | denotes | MOL1 |
T19 | 611-616 | GeneOrGeneProduct | denotes | lines |
T20 | 633-637 | GeneOrGeneProduct | denotes | MOL1 |
T21 | 641-647 | GeneOrGeneProduct | denotes | active |
T22 | 711-717 | GeneOrGeneProduct | denotes | acting |
T23 | 718-723 | GeneOrGeneProduct | denotes | CLE41 |
T24 | 774-778 | GeneOrGeneProduct | denotes | MOL1 |
T25 | 779-783 | GeneOrGeneProduct | denotes | acts |
T26 | 813-818 | GeneOrGeneProduct | denotes | CLE41 |
T27 | 871-875 | GeneOrGeneProduct | denotes | MOL1 |
T28 | 964-968 | GeneOrGeneProduct | denotes | MOL1 |
T29 | 1021-1026 | GeneOrGeneProduct | denotes | other |
T30 | 1088-1092 | GeneOrGeneProduct | denotes | MOL1 |
T31 | 1123-1127 | GeneOrGeneProduct | denotes | CLV1 |
T32 | 1152-1167 | GeneOrGeneProduct | denotes | apical meristem |
T33 | 1207-1211 | GeneOrGeneProduct | denotes | mol1 |
T34 | 1212-1219 | GeneOrGeneProduct | denotes | mutants |
T35 | 1241-1245 | GeneOrGeneProduct | denotes | MOL1 |
T36 | 1315-1319 | GeneOrGeneProduct | denotes | acid |
T37 | 1320-1327 | GeneOrGeneProduct | denotes | hormone |
T38 | 1386-1393 | GeneOrGeneProduct | denotes | lateral |
T39 | 1394-1400 | GeneOrGeneProduct | denotes | growth |
T40 | 1430-1438 | GeneOrGeneProduct | denotes | findings |
T41 | 1503-1508 | GeneOrGeneProduct | denotes | plant |
T42 | 1514-1518 | GeneOrGeneProduct | denotes | cell |
T43 | 1608-1615 | GeneOrGeneProduct | denotes | spatial |
T44 | 1701-1711 | GeneOrGeneProduct | denotes | production |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-4 | GeneOrGeneProduct | denotes | MOL1 |
T2 | 173-177 | GeneOrGeneProduct | denotes | cell |
T3 | 254-262 | GeneOrGeneProduct | denotes | receptor |
T4 | 292-332 | GeneOrGeneProduct | denotes | leucine-rich repeat receptor-like kinase |
T5 | 334-341 | GeneOrGeneProduct | denotes | LRR-RLK |
T6 | 398-402 | GeneOrGeneProduct | denotes | cell |
T7 | 430-436 | GeneOrGeneProduct | denotes | growth |
T8 | 505-512 | GeneOrGeneProduct | denotes | LRR-RLK |
T9 | 513-517 | GeneOrGeneProduct | denotes | MOL1 |
T10 | 611-616 | GeneOrGeneProduct | denotes | lines |
T11 | 633-637 | GeneOrGeneProduct | denotes | MOL1 |
T12 | 718-723 | GeneOrGeneProduct | denotes | CLE41 |
T13 | 774-778 | GeneOrGeneProduct | denotes | MOL1 |
T14 | 813-818 | GeneOrGeneProduct | denotes | CLE41 |
T15 | 871-875 | GeneOrGeneProduct | denotes | MOL1 |
T16 | 964-968 | GeneOrGeneProduct | denotes | MOL1 |
T17 | 1021-1026 | GeneOrGeneProduct | denotes | other |
T18 | 1088-1092 | GeneOrGeneProduct | denotes | MOL1 |
T19 | 1123-1127 | GeneOrGeneProduct | denotes | CLV1 |
T20 | 1152-1167 | GeneOrGeneProduct | denotes | apical meristem |
T21 | 1241-1245 | GeneOrGeneProduct | denotes | MOL1 |
T22 | 1315-1319 | GeneOrGeneProduct | denotes | acid |
T23 | 1320-1327 | GeneOrGeneProduct | denotes | hormone |
T24 | 1394-1400 | GeneOrGeneProduct | denotes | growth |
T25 | 1503-1508 | GeneOrGeneProduct | denotes | plant |
T26 | 1514-1518 | GeneOrGeneProduct | denotes | cell |
T27 | 1608-1615 | GeneOrGeneProduct | denotes | spatial |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-4 | GeneOrGeneProduct | denotes | MOL1 |
T2 | 292-332 | GeneOrGeneProduct | denotes | leucine-rich repeat receptor-like kinase |
T3 | 334-341 | GeneOrGeneProduct | denotes | LRR-RLK |
T4 | 505-512 | GeneOrGeneProduct | denotes | LRR-RLK |
T5 | 513-517 | GeneOrGeneProduct | denotes | MOL1 |
T6 | 633-637 | GeneOrGeneProduct | denotes | MOL1 |
T7 | 718-723 | GeneOrGeneProduct | denotes | CLE41 |
T8 | 774-778 | GeneOrGeneProduct | denotes | MOL1 |
T9 | 813-818 | GeneOrGeneProduct | denotes | CLE41 |
T10 | 871-875 | GeneOrGeneProduct | denotes | MOL1 |
T11 | 964-968 | GeneOrGeneProduct | denotes | MOL1 |
T12 | 1088-1092 | GeneOrGeneProduct | denotes | MOL1 |
T13 | 1123-1127 | GeneOrGeneProduct | denotes | CLV1 |
T14 | 1152-1167 | GeneOrGeneProduct | denotes | apical meristem |
T15 | 1241-1245 | GeneOrGeneProduct | denotes | MOL1 |
T16 | 1503-1508 | GeneOrGeneProduct | denotes | plant |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 276-279 | DiseaseOrPhenotypicFeature | denotes | CLE | 0013662|0007536 |
T3 | 300-304 | DiseaseOrPhenotypicFeature | denotes | rich | 0015404 |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 292-299 | ChemicalEntity | denotes | leucine | http://purl.obolibrary.org/obo/CHEBI_25017 |
T2 | 1293-1301 | ChemicalEntity | denotes | ethylene | C036216|http://purl.obolibrary.org/obo/CHEBI_29362 |
T4 | 1306-1319 | ChemicalEntity | denotes | jasmonic acid | C011006|http://purl.obolibrary.org/obo/CHEBI_18292 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 44-55 | OrganismTaxon | denotes | Arabidopsis |
T2 | 57-63 | OrganismTaxon | denotes | Plants |
T3 | 203-207 | OrganismTaxon | denotes | root |
T4 | 558-578 | OrganismTaxon | denotes | Arabidopsis thaliana |
T5 | 1408-1419 | OrganismTaxon | denotes | Arabidopsis |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T4 | 1306-1319 | ChemicalEntity | denotes | jasmonic acid | http://purl.obolibrary.org/obo/CHEBI_18292|C011006 |
T2 | 1293-1301 | ChemicalEntity | denotes | ethylene | http://purl.obolibrary.org/obo/CHEBI_29362|C036216 |
T1 | 292-299 | ChemicalEntity | denotes | leucine | http://purl.obolibrary.org/obo/CHEBI_25017 |
T16 | 1503-1508 | GeneOrGeneProduct | denotes | plant | |
T15 | 1241-1245 | GeneOrGeneProduct | denotes | MOL1 | |
T14 | 1152-1167 | GeneOrGeneProduct | denotes | apical meristem | |
T13 | 1123-1127 | GeneOrGeneProduct | denotes | CLV1 | |
T12 | 1088-1092 | GeneOrGeneProduct | denotes | MOL1 | |
T11 | 964-968 | GeneOrGeneProduct | denotes | MOL1 | |
T10 | 871-875 | GeneOrGeneProduct | denotes | MOL1 | |
T9 | 813-818 | GeneOrGeneProduct | denotes | CLE41 | |
T8 | 774-778 | GeneOrGeneProduct | denotes | MOL1 | |
T7 | 718-723 | GeneOrGeneProduct | denotes | CLE41 | |
T6 | 633-637 | GeneOrGeneProduct | denotes | MOL1 | |
T5 | 513-517 | GeneOrGeneProduct | denotes | MOL1 | |
T95245 | 505-512 | GeneOrGeneProduct | denotes | LRR-RLK | |
T3 | 334-341 | GeneOrGeneProduct | denotes | LRR-RLK | |
T68968 | 292-332 | GeneOrGeneProduct | denotes | leucine-rich repeat receptor-like kinase | |
T71170 | 0-4 | GeneOrGeneProduct | denotes | MOL1 | |
T54106 | 1408-1419 | OrganismTaxon | denotes | Arabidopsis | |
T23940 | 558-578 | OrganismTaxon | denotes | Arabidopsis thaliana | |
T69510 | 203-207 | OrganismTaxon | denotes | root | |
T57425 | 57-63 | OrganismTaxon | denotes | Plants | |
T2247 | 44-55 | OrganismTaxon | denotes | Arabidopsis |