| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-43 |
Sentence |
denotes |
Preeclampsia and superimposed preeclampsia: |
| TextSentencer_T2 |
44-61 |
Sentence |
denotes |
The same disease? |
| TextSentencer_T3 |
62-96 |
Sentence |
denotes |
The role of angiogenic biomarkers. |
| TextSentencer_T4 |
97-107 |
Sentence |
denotes |
OBJECTIVE: |
| TextSentencer_T5 |
108-326 |
Sentence |
denotes |
We aimed to compare sFlt-1 and placental growth factor (PlGF) levels and the sFlt-1/PlGF ratio between women with preeclampsia and superimposed preeclampsia to, respectively, normotensive and chronic hypertensive ones. |
| TextSentencer_T6 |
327-340 |
Sentence |
denotes |
STUDY DESIGN: |
| TextSentencer_T7 |
341-508 |
Sentence |
denotes |
We performed a prospective two-armed cohort in a tertiary teaching hospital in Sao Paulo, Brazil, including 37 normotensive and 60 chronic hypertensive pregnant women. |
| TextSentencer_T8 |
509-634 |
Sentence |
denotes |
We assessed the serum levels of sFlt-1 and PlGF at 20, 26, 32, and 36 gestational weeks by enzyme-linked immunosorbent assay. |
| TextSentencer_T9 |
635-657 |
Sentence |
denotes |
MAIN OUTCOME MEASURES: |
| TextSentencer_T10 |
658-708 |
Sentence |
denotes |
Having preeclampsia and superimposed preeclampsia. |
| TextSentencer_T11 |
709-717 |
Sentence |
denotes |
RESULTS: |
| TextSentencer_T12 |
718-873 |
Sentence |
denotes |
Among normotensive and chronic hypertensive pregnancies, 4 (10.8%) and 14 (23.3%) women developed preeclampsia and superimposed preeclampsia, respectively. |
| TextSentencer_T13 |
874-1378 |
Sentence |
denotes |
Compared with those who remained normotensive, the preeclampsia women presented higher sFlt-1 levels at 32 gestational weeks (4323.45 pg/mL vs. 2242.04 pg/mL, p = 0.019), lower PlGF levels at 20 (183.54 pg/mL vs. 337.38 pg/mL, p = 0.034), 32 (169.69 pg/mL vs. 792.53 pg/mL, p = 0.001), and 36 gestational weeks (252.99 pg/mL vs. 561.81 pg/mL, p = 0.029), and higher sFlt-1/PlGF ratios at 26 (9.02 vs. 1.84, p = 0.004), 32 (23.61 vs. 2.55, p = 0.001), and 36 gestational weeks (49.02 vs. 7.34, p = 0.029). |
| TextSentencer_T14 |
1379-1582 |
Sentence |
denotes |
On the other hand, compared with those who remained chronic hypertensive, the superimposed preeclampsia women only presented a higher sFlt-1/PlGF ratio at 32 gestational weeks (9.98 vs. 2.51, p = 0.039). |
| TextSentencer_T15 |
1583-1594 |
Sentence |
denotes |
CONCLUSION: |
| TextSentencer_T16 |
1595-1781 |
Sentence |
denotes |
Although angiogenic imbalance is clearly related to preeclampsia, it seems to play a more modest role in superimposed preeclampsia, in which other mechanisms should also be investigated. |
| T1 |
0-43 |
Sentence |
denotes |
Preeclampsia and superimposed preeclampsia: |
| T2 |
44-61 |
Sentence |
denotes |
The same disease? |
| T3 |
62-96 |
Sentence |
denotes |
The role of angiogenic biomarkers. |
| T4 |
97-107 |
Sentence |
denotes |
OBJECTIVE: |
| T5 |
108-326 |
Sentence |
denotes |
We aimed to compare sFlt-1 and placental growth factor (PlGF) levels and the sFlt-1/PlGF ratio between women with preeclampsia and superimposed preeclampsia to, respectively, normotensive and chronic hypertensive ones. |
| T6 |
327-340 |
Sentence |
denotes |
STUDY DESIGN: |
| T7 |
341-508 |
Sentence |
denotes |
We performed a prospective two-armed cohort in a tertiary teaching hospital in Sao Paulo, Brazil, including 37 normotensive and 60 chronic hypertensive pregnant women. |
| T8 |
509-634 |
Sentence |
denotes |
We assessed the serum levels of sFlt-1 and PlGF at 20, 26, 32, and 36 gestational weeks by enzyme-linked immunosorbent assay. |
| T9 |
635-657 |
Sentence |
denotes |
MAIN OUTCOME MEASURES: |
| T10 |
658-708 |
Sentence |
denotes |
Having preeclampsia and superimposed preeclampsia. |
| T11 |
709-717 |
Sentence |
denotes |
RESULTS: |
| T12 |
718-873 |
Sentence |
denotes |
Among normotensive and chronic hypertensive pregnancies, 4 (10.8%) and 14 (23.3%) women developed preeclampsia and superimposed preeclampsia, respectively. |
| T13 |
874-1378 |
Sentence |
denotes |
Compared with those who remained normotensive, the preeclampsia women presented higher sFlt-1 levels at 32 gestational weeks (4323.45 pg/mL vs. 2242.04 pg/mL, p = 0.019), lower PlGF levels at 20 (183.54 pg/mL vs. 337.38 pg/mL, p = 0.034), 32 (169.69 pg/mL vs. 792.53 pg/mL, p = 0.001), and 36 gestational weeks (252.99 pg/mL vs. 561.81 pg/mL, p = 0.029), and higher sFlt-1/PlGF ratios at 26 (9.02 vs. 1.84, p = 0.004), 32 (23.61 vs. 2.55, p = 0.001), and 36 gestational weeks (49.02 vs. 7.34, p = 0.029). |
| T14 |
1379-1582 |
Sentence |
denotes |
On the other hand, compared with those who remained chronic hypertensive, the superimposed preeclampsia women only presented a higher sFlt-1/PlGF ratio at 32 gestational weeks (9.98 vs. 2.51, p = 0.039). |
| T15 |
1583-1594 |
Sentence |
denotes |
CONCLUSION: |
| T16 |
1595-1781 |
Sentence |
denotes |
Although angiogenic imbalance is clearly related to preeclampsia, it seems to play a more modest role in superimposed preeclampsia, in which other mechanisms should also be investigated. |