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PubMed:26865089 JSONTXT

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Preeclampsia

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 105-117 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 392-404 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T3 567-579 ORPHA:275555 denotes preeclampsia

Preeclampsia-compare

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 105-117 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 392-404 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T3 567-579 ORPHA:275555 denotes preeclampsia

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-118 Sentence denotes Wnt5a inhibited human trophoblast cell line HTR8/SVneo invasion: implications for early placentation and preeclampsia.
TextSentencer_T2 119-129 Sentence denotes OBJECTIVE:
TextSentencer_T3 130-216 Sentence denotes Wnt5a and Wnt signaling play potential roles in human placental and fetal development.
TextSentencer_T4 217-432 Sentence denotes The objective of this study is to explore the role of Wnt5a in the invasion of the human trophoblast cell line HTR8/SVneo and the probable mechanism of early placentation and preeclampsia in which Wnt5a is involved.
TextSentencer_T5 433-441 Sentence denotes METHODS:
TextSentencer_T6 442-664 Sentence denotes Human first trimester villous tissues from normal pregnancies and third trimester placentas from pregnancies with or without preeclampsia (PE) were used in the detection of the expression and subcellular location of Wnt5a.
TextSentencer_T7 665-818 Sentence denotes The human trophoblast cell line HTR8/SVneo was treated with 0-400 ng/ml recombinant Wnt5a to investigate the role of Wnt5a in human trophoblast invasion.
TextSentencer_T8 819-827 Sentence denotes RESULTS:
TextSentencer_T9 828-938 Sentence denotes Human first trimester villous is accompanied by the decreased expression of Wnt5a compared with term placenta.
TextSentencer_T10 939-1018 Sentence denotes Upregulated Wnt5a was detected in PE placenta compared with the normal control.
TextSentencer_T11 1019-1128 Sentence denotes Wnt5a inhibited the migration and invasion of HTR8/SVneo cells with decreased integrin β1, α5 and N-cadherin.
TextSentencer_T12 1129-1189 Sentence denotes Moreover, Wnt5a downregulated β-catenin in HTR8/SVneo cells.
TextSentencer_T13 1190-1202 Sentence denotes CONCLUSIONS:
TextSentencer_T14 1203-1288 Sentence denotes These findings strongly suggest that Wnt5a inhibits the invasion of HTR8/SVneo cells.
TextSentencer_T15 1289-1438 Sentence denotes Decreased Wnt5a facilitates early placentation, whereas increased Wnt5a contributes to the pathogenesis of PE with insufficient trophoblast invasion.
TextSentencer_T16 1439-1542 Sentence denotes Aberrant Wnt5a may function by impairing Wnt non-canonical/β-catenin signaling pathway in trophoblasts.
T1 0-118 Sentence denotes Wnt5a inhibited human trophoblast cell line HTR8/SVneo invasion: implications for early placentation and preeclampsia.
T2 119-129 Sentence denotes OBJECTIVE:
T3 130-216 Sentence denotes Wnt5a and Wnt signaling play potential roles in human placental and fetal development.
T4 217-432 Sentence denotes The objective of this study is to explore the role of Wnt5a in the invasion of the human trophoblast cell line HTR8/SVneo and the probable mechanism of early placentation and preeclampsia in which Wnt5a is involved.
T5 433-441 Sentence denotes METHODS:
T6 442-664 Sentence denotes Human first trimester villous tissues from normal pregnancies and third trimester placentas from pregnancies with or without preeclampsia (PE) were used in the detection of the expression and subcellular location of Wnt5a.
T7 665-818 Sentence denotes The human trophoblast cell line HTR8/SVneo was treated with 0-400 ng/ml recombinant Wnt5a to investigate the role of Wnt5a in human trophoblast invasion.
T8 819-827 Sentence denotes RESULTS:
T9 828-938 Sentence denotes Human first trimester villous is accompanied by the decreased expression of Wnt5a compared with term placenta.
T10 939-1018 Sentence denotes Upregulated Wnt5a was detected in PE placenta compared with the normal control.
T11 1019-1128 Sentence denotes Wnt5a inhibited the migration and invasion of HTR8/SVneo cells with decreased integrin β1, α5 and N-cadherin.
T12 1129-1189 Sentence denotes Moreover, Wnt5a downregulated β-catenin in HTR8/SVneo cells.
T13 1190-1202 Sentence denotes CONCLUSIONS:
T14 1203-1288 Sentence denotes These findings strongly suggest that Wnt5a inhibits the invasion of HTR8/SVneo cells.
T15 1289-1438 Sentence denotes Decreased Wnt5a facilitates early placentation, whereas increased Wnt5a contributes to the pathogenesis of PE with insufficient trophoblast invasion.
T16 1439-1542 Sentence denotes Aberrant Wnt5a may function by impairing Wnt non-canonical/β-catenin signaling pathway in trophoblasts.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 22-33 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T2 306-317 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T3 675-686 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T4 797-808 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T5 1417-1428 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T6 1529-1541 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblasts
PD-UBERON-AE-B_T7 472-479 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T8 524-533 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placentas
PD-UBERON-AE-B_T9 929-937 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta
PD-UBERON-AE-B_T10 976-984 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 472-479 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 22-33 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T3 306-317 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T4 675-686 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T5 797-808 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T6 1417-1428 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T7 1529-1541 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblasts
PD-UBERON-AE-B_T8 184-193 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T9 524-533 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placentas
PD-UBERON-AE-B_T10 929-937 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta
PD-UBERON-AE-B_T11 976-984 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta