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PubMed:26810818 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-112 Sentence denotes SATB1 expression is correlated with β-catenin associated epithelial-mesenchymal transition in colorectal cancer.
TextSentencer_T2 113-243 Sentence denotes SATB1, a global gene regulator, has been implicated in the growth and metastasis of multiple cancers, including colorectal cancer.
TextSentencer_T3 244-315 Sentence denotes While the understanding about the role of SATB1 in CRC remains limited.
TextSentencer_T4 316-475 Sentence denotes The aim of our study is to investigate the expression of SATB1 in CRC, and the relationship between SATB1 expression pattern and clinicopathological variables.
TextSentencer_T5 476-590 Sentence denotes A further aim is to analyze the correlation between SATB1 expression and epithelial-mesenchymal transition in CRC.
TextSentencer_T6 591-754 Sentence denotes Immunohistochemical expression of SATB1, β-catenin, E-cadherin, CK20, Vimentin, SMA, and desmin were assessed in a cohort of 200 patients using tissue microarrays.
TextSentencer_T7 755-907 Sentence denotes SATB1 was expressed in 133 (66.5%) CRC primary lesions, 14 (28%) adjacent colorectal mucosa specimens, and 60 (75%) corresponding lymph node metastases.
TextSentencer_T8 908-1046 Sentence denotes The expression level of SATB1 was significantly higher in lymph node metastases than in CRC primary lesions and normal mucosa (P = 0.000).
TextSentencer_T9 1047-1158 Sentence denotes High expression of SATB1 in CRC was strongly correlated with poor differentiation of tumor tissues (P = 0.000).
TextSentencer_T10 1159-1376 Sentence denotes High expression of SATB1 was significantly correlated with aberrant expression of β-catenin (P = 0.0005), low expression of E-cadherin (P = 0.000) and CK20 (P = 0.000) and with high expression of Vimentin (P = 0.001).
TextSentencer_T11 1377-1433 Sentence denotes No SMA or desmin protein was expressed in the CRC cells.
TextSentencer_T12 1434-1547 Sentence denotes Our results suggested that high expression of SATB1 is significantly correlated with poor differentiation of CRC.
TextSentencer_T13 1548-1657 Sentence denotes SATB1 might promote the epithelial-mesenchymal transition by increasing the aberrant expression of β-catenin.
T1 0-112 Sentence denotes SATB1 expression is correlated with β-catenin associated epithelial-mesenchymal transition in colorectal cancer.
T2 113-243 Sentence denotes SATB1, a global gene regulator, has been implicated in the growth and metastasis of multiple cancers, including colorectal cancer.
T3 244-315 Sentence denotes While the understanding about the role of SATB1 in CRC remains limited.
T4 316-475 Sentence denotes The aim of our study is to investigate the expression of SATB1 in CRC, and the relationship between SATB1 expression pattern and clinicopathological variables.
T5 476-590 Sentence denotes A further aim is to analyze the correlation between SATB1 expression and epithelial-mesenchymal transition in CRC.
T6 591-754 Sentence denotes Immunohistochemical expression of SATB1, β-catenin, E-cadherin, CK20, Vimentin, SMA, and desmin were assessed in a cohort of 200 patients using tissue microarrays.
T7 755-907 Sentence denotes SATB1 was expressed in 133 (66.5%) CRC primary lesions, 14 (28%) adjacent colorectal mucosa specimens, and 60 (75%) corresponding lymph node metastases.
T8 908-1046 Sentence denotes The expression level of SATB1 was significantly higher in lymph node metastases than in CRC primary lesions and normal mucosa (P = 0.000).
T9 1047-1158 Sentence denotes High expression of SATB1 in CRC was strongly correlated with poor differentiation of tumor tissues (P = 0.000).
T10 1159-1376 Sentence denotes High expression of SATB1 was significantly correlated with aberrant expression of β-catenin (P = 0.0005), low expression of E-cadherin (P = 0.000) and CK20 (P = 0.000) and with high expression of Vimentin (P = 0.001).
T11 1377-1433 Sentence denotes No SMA or desmin protein was expressed in the CRC cells.
T12 1434-1547 Sentence denotes Our results suggested that high expression of SATB1 is significantly correlated with poor differentiation of CRC.
T13 1548-1657 Sentence denotes SATB1 might promote the epithelial-mesenchymal transition by increasing the aberrant expression of β-catenin.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
26810818-0#94#111#diseaseC0009402 94-111 diseaseC0009402 denotes colorectal cancer
26810818-0#94#111#diseaseC1527249 94-111 diseaseC1527249 denotes colorectal cancer
26810818-1#0#5#gene6304 113-118 gene6304 denotes SATB1
26810818-1#70#80#diseaseC0027627 183-193 diseaseC0027627 denotes metastasis
26810818-7#24#29#gene6304 932-937 gene6304 denotes SATB1
26810818-7#58#79#diseaseC0686619 966-987 diseaseC0686619 denotes lymph node metastases
0#5#gene630470#80#diseaseC0027627 26810818-1#0#5#gene6304 26810818-1#70#80#diseaseC0027627 associated_with SATB1,metastasis
24#29#gene630458#79#diseaseC0686619 26810818-7#24#29#gene6304 26810818-7#58#79#diseaseC0686619 associated_with SATB1,lymph node metastases

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2538 0-5 gene:6304 denotes SATB1
T2539 94-111 disease:C0009402 denotes colorectal cancer
T2540 113-118 gene:6304 denotes SATB1
T2541 183-193 disease:C0027627 denotes metastasis
R1 T2538 T2539 associated_with SATB1,colorectal cancer
R2 T2538 T2539 associated_with SATB1,colorectal cancer
R3 T2540 T2541 associated_with SATB1,metastasis

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 68-79 http://purl.obolibrary.org/obo/UBERON_0003104 denotes mesenchymal
PD-UBERON-AE-B_T2 560-571 http://purl.obolibrary.org/obo/UBERON_0003104 denotes mesenchymal
PD-UBERON-AE-B_T3 1583-1594 http://purl.obolibrary.org/obo/UBERON_0003104 denotes mesenchymal
PD-UBERON-AE-B_T4 735-741 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T5 1138-1145 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T6 829-846 http://purl.obolibrary.org/obo/UBERON_0013067 denotes colorectal mucosa
PD-UBERON-AE-B_T7 840-846 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
PD-UBERON-AE-B_T8 1027-1033 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
PD-UBERON-AE-B_T9 885-890 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T10 966-971 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T11 885-895 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
PD-UBERON-AE-B_T12 966-976 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 885-890 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T2 966-971 http://purl.obolibrary.org/obo/UBERON_0002391 denotes lymph
PD-UBERON-AE-B_T3 885-895 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
PD-UBERON-AE-B_T4 966-976 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
PD-UBERON-AE-B_T5 735-741 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T6 1138-1145 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T7 68-79 http://purl.obolibrary.org/obo/UBERON_0003104 denotes mesenchymal
PD-UBERON-AE-B_T8 560-571 http://purl.obolibrary.org/obo/UBERON_0003104 denotes mesenchymal
PD-UBERON-AE-B_T9 1583-1594 http://purl.obolibrary.org/obo/UBERON_0003104 denotes mesenchymal
PD-UBERON-AE-B_T10 829-846 http://purl.obolibrary.org/obo/UBERON_0013067 denotes colorectal mucosa
PD-UBERON-AE-B_T11 840-846 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
PD-UBERON-AE-B_T12 1027-1033 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa