PubMed:26762172 / 1373-1685
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/26762172","sourcedb":"PubMed","sourceid":"26762172","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/26762172","text":"In particular, docking solutions were obtained in which i) a single roneparstat molecule interacts with both heparin-binding domains (HBD) of heparanase or ii) two fragments of roneparstat interact with either HBD-1 or HBD-2, consistent with the possibility of different inhibitor:enzyme binding stoichiometries.","tracks":[{"project":"Glycan-Motif","denotations":[{"id":"T3","span":{"begin":109,"end":116},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T4","span":{"begin":109,"end":116},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"}],"attributes":[{"subj":"T3","pred":"source","obj":"Glycan-Motif"},{"subj":"T4","pred":"source","obj":"Glycan-Motif"}]},{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T3","span":{"begin":109,"end":116},"obj":"Glycan_Motif"}],"attributes":[{"id":"A3","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR"},{"id":"A4","pred":"image","subj":"T3","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO"},{"subj":"T3","pred":"source","obj":"GlyCosmos6-Glycan-Motif-Image"}]},{"project":"GlyCosmos6-Glycan-Motif-Structure","denotations":[{"id":"T3","span":{"begin":109,"end":116},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T4","span":{"begin":109,"end":116},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"}],"attributes":[{"subj":"T3","pred":"source","obj":"GlyCosmos6-Glycan-Motif-Structure"},{"subj":"T4","pred":"source","obj":"GlyCosmos6-Glycan-Motif-Structure"}]},{"project":"sentences","denotations":[{"id":"TextSentencer_T10","span":{"begin":0,"end":312},"obj":"Sentence"},{"id":"T10","span":{"begin":0,"end":312},"obj":"Sentence"},{"id":"T10","span":{"begin":0,"end":312},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T10","pred":"source","obj":"sentences"},{"subj":"T10","pred":"source","obj":"sentences"},{"subj":"T10","pred":"source","obj":"sentences"}]},{"project":"GlycoBiology-FMA","denotations":[{"id":"_T20","span":{"begin":109,"end":116},"obj":"FMAID:167420"},{"id":"_T21","span":{"begin":109,"end":116},"obj":"FMAID:82839"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"attributes":[{"subj":"_T20","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T21","pred":"source","obj":"GlycoBiology-FMA"}]},{"project":"uniprot-human","denotations":[{"id":"T8","span":{"begin":142,"end":152},"obj":"http://www.uniprot.org/uniprot/Q9Y251"},{"id":"T11","span":{"begin":134,"end":137},"obj":"http://www.uniprot.org/uniprot/P02042"},{"id":"T12","span":{"begin":210,"end":213},"obj":"http://www.uniprot.org/uniprot/P02042"},{"id":"T13","span":{"begin":219,"end":222},"obj":"http://www.uniprot.org/uniprot/P02042"},{"id":"T14","span":{"begin":156,"end":158},"obj":"http://www.uniprot.org/uniprot/Q8SNA0"}],"attributes":[{"subj":"T8","pred":"source","obj":"uniprot-human"},{"subj":"T11","pred":"source","obj":"uniprot-human"},{"subj":"T12","pred":"source","obj":"uniprot-human"},{"subj":"T13","pred":"source","obj":"uniprot-human"},{"subj":"T14","pred":"source","obj":"uniprot-human"}]},{"project":"uniprot-mouse","denotations":[{"id":"T8","span":{"begin":142,"end":152},"obj":"http://www.uniprot.org/uniprot/Q6YGZ1"},{"id":"T10","span":{"begin":156,"end":158},"obj":"http://www.uniprot.org/uniprot/P04441"}],"attributes":[{"subj":"T8","pred":"source","obj":"uniprot-mouse"},{"subj":"T10","pred":"source","obj":"uniprot-mouse"}]},{"project":"GO-MF","denotations":[{"id":"T2","span":{"begin":117,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0070026"},{"id":"T3","span":{"begin":288,"end":295},"obj":"http://purl.obolibrary.org/obo/GO_0070026"},{"id":"T5","span":{"begin":117,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0003680"},{"id":"T6","span":{"begin":288,"end":295},"obj":"http://purl.obolibrary.org/obo/GO_0003680"},{"id":"T8","span":{"begin":117,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0017091"},{"id":"T9","span":{"begin":288,"end":295},"obj":"http://purl.obolibrary.org/obo/GO_0017091"},{"id":"T11","span":{"begin":117,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T12","span":{"begin":288,"end":295},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T13","span":{"begin":109,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0008201"}],"attributes":[{"subj":"T2","pred":"source","obj":"GO-MF"},{"subj":"T3","pred":"source","obj":"GO-MF"},{"subj":"T5","pred":"source","obj":"GO-MF"},{"subj":"T6","pred":"source","obj":"GO-MF"},{"subj":"T8","pred":"source","obj":"GO-MF"},{"subj":"T9","pred":"source","obj":"GO-MF"},{"subj":"T11","pred":"source","obj":"GO-MF"},{"subj":"T12","pred":"source","obj":"GO-MF"},{"subj":"T13","pred":"source","obj":"GO-MF"}]},{"project":"GlycoBiology-Motifs","denotations":[{"id":"T2","span":{"begin":109,"end":116},"obj":"http://rdf.glycoinfo.org/glycan/G54161DR"}],"attributes":[{"subj":"T2","pred":"source","obj":"GlycoBiology-Motifs"}]},{"project":"mondo_disease","denotations":[{"id":"T4","span":{"begin":134,"end":137},"obj":"Disease"},{"id":"T5","span":{"begin":210,"end":213},"obj":"Disease"},{"id":"T6","span":{"begin":219,"end":222},"obj":"Disease"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0007799"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0007799"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0007799"},{"subj":"T4","pred":"source","obj":"mondo_disease"},{"subj":"T5","pred":"source","obj":"mondo_disease"},{"subj":"T6","pred":"source","obj":"mondo_disease"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Glycan-Motif","color":"#939bec","default":true},{"id":"GlyCosmos6-Glycan-Motif-Image","color":"#b5ec93"},{"id":"GlyCosmos6-Glycan-Motif-Structure","color":"#ec93cf"},{"id":"sentences","color":"#93e9ec"},{"id":"GlycoBiology-FMA","color":"#ecd493"},{"id":"uniprot-human","color":"#ba93ec"},{"id":"uniprot-mouse","color":"#93eca0"},{"id":"GO-MF","color":"#ec939f"},{"id":"GlycoBiology-Motifs","color":"#93b9ec"},{"id":"mondo_disease","color":"#d3ec93"}]}]}}