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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 44-57 https://glytoucan.org/Structures/Glycans/G17108EX denotes Blood Group A
T2 44-57 https://glytoucan.org/Structures/Glycans/G58507AZ denotes Blood Group A
T3 244-257 https://glytoucan.org/Structures/Glycans/G17108EX denotes blood group A
T4 244-257 https://glytoucan.org/Structures/Glycans/G58507AZ denotes blood group A
T5 1078-1088 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T6 1274-1287 https://glytoucan.org/Structures/Glycans/G17108EX denotes blood group A
T7 1274-1287 https://glytoucan.org/Structures/Glycans/G58507AZ denotes blood group A

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 44-57 Glycan_Motif denotes Blood Group A https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58507AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17108EX
T3 244-257 Glycan_Motif denotes blood group A https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58507AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17108EX
T5 1078-1088 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T6 1274-1287 Glycan_Motif denotes blood group A https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58507AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17108EX

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 325-328 http://www.glycoepitope.jp/epitopes/AN0541 denotes T36
T2 1078-1088 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
TextSentencer_T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
TextSentencer_T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
TextSentencer_T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
TextSentencer_T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
TextSentencer_T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
TextSentencer_T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
TextSentencer_T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
TextSentencer_T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
TextSentencer_T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
TextSentencer_T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.
T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.
T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 44-57 https://glytoucan.org/Structures/Glycans/G17108EX denotes Blood Group A
T2 44-57 https://glytoucan.org/Structures/Glycans/G58507AZ denotes Blood Group A
T3 244-257 https://glytoucan.org/Structures/Glycans/G17108EX denotes blood group A
T4 244-257 https://glytoucan.org/Structures/Glycans/G58507AZ denotes blood group A
T5 1078-1088 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T6 1274-1287 https://glytoucan.org/Structures/Glycans/G17108EX denotes blood group A
T7 1274-1287 https://glytoucan.org/Structures/Glycans/G58507AZ denotes blood group A

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 44-49 http://purl.obolibrary.org/obo/MAT_0000083 denotes Blood
T2 44-49 http://purl.obolibrary.org/obo/MAT_0000315 denotes Blood
T3 244-249 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T4 244-249 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T5 1274-1279 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T6 1274-1279 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 44-49 FMAID:256053 denotes Blood
_T2 77-87 FMAID:167180 denotes Antibodies
_T3 155-167 FMAID:82737 denotes carbohydrate
_T4 155-167 FMAID:197276 denotes carbohydrate
_T5 176-186 FMAID:167180 denotes antibodies
_T6 226-236 FMAID:167180 denotes antibodies
_T7 244-249 FMAID:256053 denotes blood
_T8 274-284 FMAID:167180 denotes Antibodies
_T9 546-556 FMAID:167180 denotes antibodies
_T10 634-650 FMAID:196731 denotes oligosaccharides
_T11 634-650 FMAID:82742 denotes oligosaccharides
_T12 668-678 FMAID:167180 denotes antibodies
_T13 770-776 FMAID:146304 denotes points
_T14 770-776 FMAID:50596 denotes points
_T15 903-913 FMAID:167180 denotes antibodies
_T16 1035-1045 FMAID:167180 denotes antibodies
_T17 1098-1106 FMAID:167180 denotes antibody
_T18 1169-1175 FMAID:165609 denotes serine
_T19 1169-1175 FMAID:67710 denotes serine
_T20 1169-1175 FMAID:82764 denotes serine
_T21 1169-1175 FMAID:196753 denotes serine
_T22 1274-1279 FMAID:256053 denotes blood
_T23 1288-1298 FMAID:167180 denotes antibodies

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 50-55 http://purl.bioontology.org/ontology/STY/T096 denotes Group
T2 66-76 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes Monoclonal
T3 215-225 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes monoclonal
T4 250-255 http://purl.bioontology.org/ontology/STY/T096 denotes group
T5 1280-1285 http://purl.bioontology.org/ontology/STY/T096 denotes group

GO-MF

Id Subject Object Predicate Lexical cue
T1 58-65 http://purl.obolibrary.org/obo/GO_0070026 denotes Binding
T2 168-175 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T3 862-869 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T4 887-894 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T5 58-65 http://purl.obolibrary.org/obo/GO_0003680 denotes Binding
T6 168-175 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T7 862-869 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T8 887-894 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T9 58-65 http://purl.obolibrary.org/obo/GO_0017091 denotes Binding
T10 168-175 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T11 862-869 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T12 887-894 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T13 58-65 http://purl.obolibrary.org/obo/GO_0005488 denotes Binding
T14 168-175 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T15 862-869 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T16 887-894 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T17 77-87 http://purl.obolibrary.org/obo/GO_0003823 denotes Antibodies
T18 176-186 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T19 226-236 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T20 546-556 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T21 668-678 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T22 903-913 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T23 1035-1045 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T24 1098-1106 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T25 155-175 http://purl.obolibrary.org/obo/GO_0030246 denotes carbohydrate binding

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 44-49 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T2 244-249 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T3 1274-1279 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 44-49 http://purl.obolibrary.org/obo/MAT_0000315 denotes Blood
T2 44-49 http://purl.obolibrary.org/obo/MAT_0000083 denotes Blood
T3 244-249 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T4 244-249 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T5 1274-1279 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T6 1274-1279 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 44-55 http://rdf.glycoinfo.org/glycan/G00066MO denotes Blood Group
T2 244-255 http://rdf.glycoinfo.org/glycan/G00066MO denotes blood group
T3 1274-1285 http://rdf.glycoinfo.org/glycan/G00066MO denotes blood group

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 1078-1080 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 1078-1088 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T2 325-328 http://www.glycoepitope.jp/epitopes/AN0541 denotes T36

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 1144-1150 "http://rdf.glycoinfo.org/glycan/G23425WZ" denotes GalNAc
GlycanIUPAC_T2 1144-1150 "http://rdf.glycoinfo.org/glycan/G02874VH" denotes GalNAc
GlycanIUPAC_T3 1144-1150 "http://rdf.glycoinfo.org/glycan/G99699DW" denotes GalNAc
GlycanIUPAC_T4 1144-1150 "http://rdf.glycoinfo.org/glycan/G22074RM" denotes GalNAc
GlycanIUPAC_T5 1144-1150 "http://rdf.glycoinfo.org/glycan/G48535VZ" denotes GalNAc
GlycanIUPAC_T6 1144-1150 "http://rdf.glycoinfo.org/glycan/G39738WL" denotes GalNAc
GlycanIUPAC_T7 1144-1150 "http://rdf.glycoinfo.org/glycan/G42313WU" denotes GalNAc
GlycanIUPAC_T8 1144-1150 "http://rdf.glycoinfo.org/glycan/G00393CK" denotes GalNAc
GlycanIUPAC_T9 1144-1150 "http://rdf.glycoinfo.org/glycan/G42649EX" denotes GalNAc
GlycanIUPAC_T10 1144-1150 "http://rdf.glycoinfo.org/glycan/G46880SB" denotes GalNAc
GlycanIUPAC_T11 1144-1150 "http://rdf.glycoinfo.org/glycan/G75599IR" denotes GalNAc
GlycanIUPAC_T12 1144-1150 "http://rdf.glycoinfo.org/glycan/G58985MU" denotes GalNAc
GlycanIUPAC_T13 1144-1150 "http://rdf.glycoinfo.org/glycan/G92517PO" denotes GalNAc
GlycanIUPAC_T14 1144-1150 "http://rdf.glycoinfo.org/glycan/G88512YL" denotes GalNAc
GlycanIUPAC_T15 1144-1150 "http://rdf.glycoinfo.org/glycan/G41473NX" denotes GalNAc
GlycanIUPAC_T16 1144-1150 "http://rdf.glycoinfo.org/glycan/G71089RB" denotes GalNAc
GlycanIUPAC_T17 1144-1150 "http://rdf.glycoinfo.org/glycan/G73485GZ" denotes GalNAc
GlycanIUPAC_T18 1144-1150 "http://rdf.glycoinfo.org/glycan/G61406KC" denotes GalNAc
GlycanIUPAC_T19 1144-1150 "http://rdf.glycoinfo.org/glycan/G34412GZ" denotes GalNAc
GlycanIUPAC_T20 1144-1150 "http://rdf.glycoinfo.org/glycan/G67209FP" denotes GalNAc
GlycanIUPAC_T21 1144-1150 "http://rdf.glycoinfo.org/glycan/G61442IL" denotes GalNAc
GlycanIUPAC_T22 1144-1150 "http://rdf.glycoinfo.org/glycan/G93729MV" denotes GalNAc
GlycanIUPAC_T23 1144-1150 "http://rdf.glycoinfo.org/glycan/G92144AE" denotes GalNAc

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 44-49 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
PD-UBERON-AE-B_T2 244-249 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T3 1274-1279 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1061-1066 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 44-49 Body_part denotes Blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T3 244-249 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T5 1274-1279 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 1061-1066 Phenotype denotes tumor HP:0002664

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 44-57 Glycan denotes Blood Group A https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO
T2 563-569 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T3 1078-1088 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T4 1144-1150 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 325-328 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T36 http://www.glycoepitope.jp/epitopes/AN0541
T2 1078-1088 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1061-1066 Phenotype denotes tumor HP:0002664

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 1061-1066 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 44-49 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T2 244-249 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 1274-1279 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 44-49 Body_part denotes Blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T3 244-249 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T5 1274-1279 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
TextSentencer_T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
TextSentencer_T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
TextSentencer_T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
TextSentencer_T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
TextSentencer_T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
TextSentencer_T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
TextSentencer_T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
TextSentencer_T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
TextSentencer_T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
TextSentencer_T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.
T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.
T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-88 Sentence denotes Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies.
T2 89-187 Sentence denotes Information about specificity and affinity is critical for use of carbohydrate binding antibodies.
T3 188-273 Sentence denotes Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen.
T4 274-468 Sentence denotes Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition.
T5 469-533 Sentence denotes Our studies highlight several noteworthy recognition properties.
T6 534-651 Sentence denotes First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides.
T7 652-753 Sentence denotes Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains.
T8 754-879 Sentence denotes These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength.
T9 880-1021 Sentence denotes Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition.
T10 1022-1184 Sentence denotes Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue.
T11 1185-1299 Sentence denotes Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 44-57 Glycan denotes Blood Group A https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO
T2 563-569 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T3 1078-1088 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T4 1144-1150 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 325-328 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T36 http://www.glycoepitope.jp/epitopes/AN0541
T2 1078-1088 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 44-49 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T2 244-249 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 1274-1279 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178