PubMed:26755806
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 44-57 | https://glytoucan.org/Structures/Glycans/G17108EX | denotes | Blood Group A |
| T2 | 44-57 | https://glytoucan.org/Structures/Glycans/G58507AZ | denotes | Blood Group A |
| T3 | 244-257 | https://glytoucan.org/Structures/Glycans/G17108EX | denotes | blood group A |
| T4 | 244-257 | https://glytoucan.org/Structures/Glycans/G58507AZ | denotes | blood group A |
| T5 | 1078-1088 | https://glytoucan.org/Structures/Glycans/G57321FI | denotes | Tn antigen |
| T6 | 1274-1287 | https://glytoucan.org/Structures/Glycans/G17108EX | denotes | blood group A |
| T7 | 1274-1287 | https://glytoucan.org/Structures/Glycans/G58507AZ | denotes | blood group A |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 44-57 | Glycan_Motif | denotes | Blood Group A | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58507AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17108EX |
| T3 | 244-257 | Glycan_Motif | denotes | blood group A | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58507AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17108EX |
| T5 | 1078-1088 | Glycan_Motif | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI |
| T6 | 1274-1287 | Glycan_Motif | denotes | blood group A | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58507AZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17108EX |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 325-328 | http://www.glycoepitope.jp/epitopes/AN0541 | denotes | T36 |
| T2 | 1078-1088 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigen |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-88 | Sentence | denotes | Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies. |
| TextSentencer_T2 | 89-187 | Sentence | denotes | Information about specificity and affinity is critical for use of carbohydrate binding antibodies. |
| TextSentencer_T3 | 188-273 | Sentence | denotes | Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen. |
| TextSentencer_T4 | 274-468 | Sentence | denotes | Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition. |
| TextSentencer_T5 | 469-533 | Sentence | denotes | Our studies highlight several noteworthy recognition properties. |
| TextSentencer_T6 | 534-651 | Sentence | denotes | First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides. |
| TextSentencer_T7 | 652-753 | Sentence | denotes | Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains. |
| TextSentencer_T8 | 754-879 | Sentence | denotes | These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength. |
| TextSentencer_T9 | 880-1021 | Sentence | denotes | Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition. |
| TextSentencer_T10 | 1022-1184 | Sentence | denotes | Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue. |
| TextSentencer_T11 | 1185-1299 | Sentence | denotes | Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies. |
| T10 | 1022-1184 | Sentence | denotes | Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue. |
| T11 | 1185-1299 | Sentence | denotes | Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies. |
| T9 | 880-1021 | Sentence | denotes | Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition. |
| T1 | 0-88 | Sentence | denotes | Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies. |
| T2 | 89-187 | Sentence | denotes | Information about specificity and affinity is critical for use of carbohydrate binding antibodies. |
| T3 | 188-273 | Sentence | denotes | Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen. |
| T4 | 274-468 | Sentence | denotes | Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition. |
| T5 | 469-533 | Sentence | denotes | Our studies highlight several noteworthy recognition properties. |
| T6 | 534-651 | Sentence | denotes | First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides. |
| T7 | 652-753 | Sentence | denotes | Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains. |
| T8 | 754-879 | Sentence | denotes | These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength. |
| T1 | 0-88 | Sentence | denotes | Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies. |
| T2 | 89-187 | Sentence | denotes | Information about specificity and affinity is critical for use of carbohydrate binding antibodies. |
| T3 | 188-273 | Sentence | denotes | Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen. |
| T4 | 274-468 | Sentence | denotes | Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition. |
| T5 | 469-533 | Sentence | denotes | Our studies highlight several noteworthy recognition properties. |
| T6 | 534-651 | Sentence | denotes | First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides. |
| T7 | 652-753 | Sentence | denotes | Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains. |
| T8 | 754-879 | Sentence | denotes | These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength. |
| T9 | 880-1021 | Sentence | denotes | Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition. |
| T10 | 1022-1184 | Sentence | denotes | Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue. |
| T11 | 1185-1299 | Sentence | denotes | Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 44-57 | https://glytoucan.org/Structures/Glycans/G17108EX | denotes | Blood Group A |
| T2 | 44-57 | https://glytoucan.org/Structures/Glycans/G58507AZ | denotes | Blood Group A |
| T3 | 244-257 | https://glytoucan.org/Structures/Glycans/G17108EX | denotes | blood group A |
| T4 | 244-257 | https://glytoucan.org/Structures/Glycans/G58507AZ | denotes | blood group A |
| T5 | 1078-1088 | https://glytoucan.org/Structures/Glycans/G57321FI | denotes | Tn antigen |
| T6 | 1274-1287 | https://glytoucan.org/Structures/Glycans/G17108EX | denotes | blood group A |
| T7 | 1274-1287 | https://glytoucan.org/Structures/Glycans/G58507AZ | denotes | blood group A |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 44-49 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | Blood |
| T2 | 44-49 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | Blood |
| T3 | 244-249 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T4 | 244-249 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T5 | 1274-1279 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T6 | 1274-1279 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 44-49 | FMAID:256053 | denotes | Blood |
| _T2 | 77-87 | FMAID:167180 | denotes | Antibodies |
| _T3 | 155-167 | FMAID:82737 | denotes | carbohydrate |
| _T4 | 155-167 | FMAID:197276 | denotes | carbohydrate |
| _T5 | 176-186 | FMAID:167180 | denotes | antibodies |
| _T6 | 226-236 | FMAID:167180 | denotes | antibodies |
| _T7 | 244-249 | FMAID:256053 | denotes | blood |
| _T8 | 274-284 | FMAID:167180 | denotes | Antibodies |
| _T9 | 546-556 | FMAID:167180 | denotes | antibodies |
| _T10 | 634-650 | FMAID:196731 | denotes | oligosaccharides |
| _T11 | 634-650 | FMAID:82742 | denotes | oligosaccharides |
| _T12 | 668-678 | FMAID:167180 | denotes | antibodies |
| _T13 | 770-776 | FMAID:146304 | denotes | points |
| _T14 | 770-776 | FMAID:50596 | denotes | points |
| _T15 | 903-913 | FMAID:167180 | denotes | antibodies |
| _T16 | 1035-1045 | FMAID:167180 | denotes | antibodies |
| _T17 | 1098-1106 | FMAID:167180 | denotes | antibody |
| _T18 | 1169-1175 | FMAID:165609 | denotes | serine |
| _T19 | 1169-1175 | FMAID:67710 | denotes | serine |
| _T20 | 1169-1175 | FMAID:82764 | denotes | serine |
| _T21 | 1169-1175 | FMAID:196753 | denotes | serine |
| _T22 | 1274-1279 | FMAID:256053 | denotes | blood |
| _T23 | 1288-1298 | FMAID:167180 | denotes | antibodies |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-55 | http://purl.bioontology.org/ontology/STY/T096 | denotes | Group |
| T2 | 66-76 | http://purl.bioontology.org/ontology/NCBITAXON/608684 | denotes | Monoclonal |
| T3 | 215-225 | http://purl.bioontology.org/ontology/NCBITAXON/608684 | denotes | monoclonal |
| T4 | 250-255 | http://purl.bioontology.org/ontology/STY/T096 | denotes | group |
| T5 | 1280-1285 | http://purl.bioontology.org/ontology/STY/T096 | denotes | group |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 58-65 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | Binding |
| T2 | 168-175 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T3 | 862-869 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T4 | 887-894 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T5 | 58-65 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | Binding |
| T6 | 168-175 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T7 | 862-869 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T8 | 887-894 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T9 | 58-65 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | Binding |
| T10 | 168-175 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T11 | 862-869 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T12 | 887-894 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T13 | 58-65 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | Binding |
| T14 | 168-175 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T15 | 862-869 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T16 | 887-894 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T17 | 77-87 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | Antibodies |
| T18 | 176-186 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
| T19 | 226-236 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
| T20 | 546-556 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
| T21 | 668-678 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
| T22 | 903-913 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
| T23 | 1035-1045 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
| T24 | 1098-1106 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibody |
| T25 | 155-175 | http://purl.obolibrary.org/obo/GO_0030246 | denotes | carbohydrate binding |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 44-49 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | Blood |
| T2 | 244-249 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T3 | 1274-1279 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 44-49 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | Blood |
| T2 | 44-49 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | Blood |
| T3 | 244-249 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T4 | 244-249 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T5 | 1274-1279 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T6 | 1274-1279 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 44-55 | http://rdf.glycoinfo.org/glycan/G00066MO | denotes | Blood Group |
| T2 | 244-255 | http://rdf.glycoinfo.org/glycan/G00066MO | denotes | blood group |
| T3 | 1274-1285 | http://rdf.glycoinfo.org/glycan/G00066MO | denotes | blood group |
Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| Lectin_T1 | 1078-1080 | https://acgg.asia/db/lfdb/LfDB0021 | denotes | Tn |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 1078-1088 | http://www.glycoepitope.jp/epitopes/EP0021 | denotes | Tn antigen |
| PD-GlycoEpitope-B_T2 | 325-328 | http://www.glycoepitope.jp/epitopes/AN0541 | denotes | T36 |
GlyTouCan-IUPAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| GlycanIUPAC_T1 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G23425WZ" | denotes | GalNAc |
| GlycanIUPAC_T2 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G02874VH" | denotes | GalNAc |
| GlycanIUPAC_T3 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G99699DW" | denotes | GalNAc |
| GlycanIUPAC_T4 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G22074RM" | denotes | GalNAc |
| GlycanIUPAC_T5 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G48535VZ" | denotes | GalNAc |
| GlycanIUPAC_T6 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G39738WL" | denotes | GalNAc |
| GlycanIUPAC_T7 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G42313WU" | denotes | GalNAc |
| GlycanIUPAC_T8 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G00393CK" | denotes | GalNAc |
| GlycanIUPAC_T9 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G42649EX" | denotes | GalNAc |
| GlycanIUPAC_T10 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G46880SB" | denotes | GalNAc |
| GlycanIUPAC_T11 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G75599IR" | denotes | GalNAc |
| GlycanIUPAC_T12 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G58985MU" | denotes | GalNAc |
| GlycanIUPAC_T13 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G92517PO" | denotes | GalNAc |
| GlycanIUPAC_T14 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G88512YL" | denotes | GalNAc |
| GlycanIUPAC_T15 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G41473NX" | denotes | GalNAc |
| GlycanIUPAC_T16 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G71089RB" | denotes | GalNAc |
| GlycanIUPAC_T17 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G73485GZ" | denotes | GalNAc |
| GlycanIUPAC_T18 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G61406KC" | denotes | GalNAc |
| GlycanIUPAC_T19 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G34412GZ" | denotes | GalNAc |
| GlycanIUPAC_T20 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G67209FP" | denotes | GalNAc |
| GlycanIUPAC_T21 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G61442IL" | denotes | GalNAc |
| GlycanIUPAC_T22 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G93729MV" | denotes | GalNAc |
| GlycanIUPAC_T23 | 1144-1150 | "http://rdf.glycoinfo.org/glycan/G92144AE" | denotes | GalNAc |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 44-49 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | Blood |
| PD-UBERON-AE-B_T2 | 244-249 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T3 | 1274-1279 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1061-1066 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 44-49 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 244-249 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T5 | 1274-1279 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1061-1066 | Phenotype | denotes | tumor | HP:0002664 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 44-57 | Glycan | denotes | Blood Group A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T2 | 563-569 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T3 | 1078-1088 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
| T4 | 1144-1150 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 325-328 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T36 | http://www.glycoepitope.jp/epitopes/AN0541 |
| T2 | 1078-1088 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1061-1066 | Phenotype | denotes | tumor | HP:0002664 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 44-57 | Glycan | denotes | Blood Group A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T2 | 244-257 | Glycan | denotes | blood group A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T3 | 259-263 | Glycan | denotes | BG-A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T4 | 563-569 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T5 | 585-589 | Glycan | denotes | BG-A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T6 | 629-633 | Glycan | denotes | BG-A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T7 | 694-698 | Glycan | denotes | BG-A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
| T8 | 1078-1088 | Glycan | denotes | Tn antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI |
| T9 | 1144-1150 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T10 | 1274-1287 | Glycan | denotes | blood group A | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00066MO |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1061-1066 | Disease | denotes | tumor | MONDO:0005070 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 44-49 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 244-249 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T3 | 1274-1279 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-88 | Sentence | denotes | Diverse Molecular Recognition Properties of Blood Group A Binding Monoclonal Antibodies. |
| T2 | 89-187 | Sentence | denotes | Information about specificity and affinity is critical for use of carbohydrate binding antibodies. |
| T3 | 188-273 | Sentence | denotes | Herein, we evaluated eight monoclonal antibodies to the blood group A (BG-A) antigen. |
| T4 | 274-468 | Sentence | denotes | Antibodies 87-G, 9A, HE-10, HE-24, HE-193, HE-195, T36, and Z2A were profiled on a glycan microarray to assess specificity, relative affinity, and the influence of glycan density on recognition. |
| T5 | 469-533 | Sentence | denotes | Our studies highlight several noteworthy recognition properties. |
| T6 | 534-651 | Sentence | denotes | First, most antibodies bound GalNAcα1-3Gal and the BG-A trisaccharide nearly as well as larger BG-A oligosaccharides. |
| T7 | 652-753 | Sentence | denotes | Second, several antibodies only bound the BG-A trisaccharide when displayed on certain glycan chains. |
| T8 | 754-879 | Sentence | denotes | These first two points indicate that the carrier glycan chains primarily influence selectivity, rather than binding strength. |
| T9 | 880-1021 | Sentence | denotes | Third, binding of some antibodies was highly dependent on glycan density, illustrating the importance of glycan presentation for recognition. |
| T10 | 1022-1184 | Sentence | denotes | Fourth, some antibodies recognized the tumor-associated Tn antigen, and one antibody only bound the variant composed of a GalNAc alpha-linked to a serine residue. |
| T11 | 1185-1299 | Sentence | denotes | Collectively, these results provide new insights into the recognition properties of anti-blood group A antibodies. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 325-328 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T36 | http://www.glycoepitope.jp/epitopes/AN0541 |
| T2 | 1078-1088 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tn antigen | http://www.glycoepitope.jp/epitopes/EP0021 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 44-49 | Body_part | denotes | Blood | FMA:9670 |
| T2 | 244-249 | Body_part | denotes | blood | FMA:9670 |
| T3 | 1274-1279 | Body_part | denotes | blood | FMA:9670 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 44-49 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000315 |
| T2 | 244-249 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 1274-1279 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 44-49 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 244-249 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T3 | 1274-1279 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |