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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 69-76 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 384-390 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T3 448-455 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 448-455 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 665-672 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T6 832-839 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T7 963-970 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T8 990-997 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T9 990-997 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T10 1063-1070 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T11 1063-1070 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T12 1095-1102 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T13 1095-1102 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T14 1215-1222 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T15 1268-1275 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T16 1439-1446 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T17 1645-1651 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T18 1693-1700 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T19 1775-1782 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 69-76 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T2 384-390 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO
T3 448-455 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T5 665-672 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T6 832-839 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T7 963-970 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T8 990-997 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T10 1063-1070 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T12 1095-1102 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T14 1215-1222 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T15 1268-1275 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T16 1439-1446 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T17 1645-1651 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO
T18 1693-1700 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T19 1775-1782 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 69-76 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 384-390 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T3 448-455 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 448-455 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 665-672 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T6 832-839 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T7 963-970 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T8 990-997 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T9 990-997 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T10 1063-1070 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T11 1063-1070 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T12 1095-1102 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T13 1095-1102 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T14 1215-1222 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T15 1268-1275 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T16 1439-1446 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T17 1645-1651 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T18 1693-1700 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T19 1775-1782 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-135 Sentence denotes Comparison of biological activities of human antithrombins with high-mannose or complex- type nonfucosylated N-linked oligosaccharides.
TextSentencer_T2 136-286 Sentence denotes The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics.
TextSentencer_T3 287-473 Sentence denotes Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by changing its heparin binding affinity.
TextSentencer_T4 474-614 Sentence denotes In human plasma, AT circulates as a mixture of the α-form bearing four oligosaccharides and the β-form lacking an oligosaccharide at Asn135.
TextSentencer_T5 615-758 Sentence denotes However, it remains unclear how the immature high-mannose-type oligosaccharides produced by mammalian cells affect biological activities of AT.
TextSentencer_T6 759-858 Sentence denotes Here, we succeeded in directly comparing the activities between the high-mannose and complex-types.
TextSentencer_T7 859-1015 Sentence denotes Interestingly, although there were no substantial differences in thrombin inhibitory activity, the high-mannose-type showed higher heparin binding affinity.
TextSentencer_T8 1016-1228 Sentence denotes The anticoagulant activities were increased by heparin and correlated with the heparin binding affinity, resulting in the strongest anticoagulant activity being displayed in the β-form with the high-mannose-type.
TextSentencer_T9 1229-1342 Sentence denotes In pharmacokinetic profiling, the high-mannose-type showed a much shorter plasma half-life than the complex-type.
TextSentencer_T10 1343-1539 Sentence denotes The β-form was found to have a prolonged plasma half-life compared with the α-form for the high-mannose-type; conversely, the α-form showed a longer half-life than the β-form for the complex-type.
TextSentencer_T11 1540-1740 Sentence denotes The present study highlights that AT physiological activities are strictly controlled not only by a core fucose at the reducing end but also by the high-mannose-type structures at the nonreducing end.
TextSentencer_T12 1741-1913 Sentence denotes The β-form with the immature high-mannose-type appears to function as a more potent anticoagulant than the AT typically found in human plasma, once it emerges in the blood.
T1 0-135 Sentence denotes Comparison of biological activities of human antithrombins with high-mannose or complex- type nonfucosylated N-linked oligosaccharides.
T2 136-286 Sentence denotes The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics.
T3 287-473 Sentence denotes Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by changing its heparin binding affinity.
T4 474-614 Sentence denotes In human plasma, AT circulates as a mixture of the α-form bearing four oligosaccharides and the β-form lacking an oligosaccharide at Asn135.
T5 615-758 Sentence denotes However, it remains unclear how the immature high-mannose-type oligosaccharides produced by mammalian cells affect biological activities of AT.
T6 759-858 Sentence denotes Here, we succeeded in directly comparing the activities between the high-mannose and complex-types.
T7 859-1015 Sentence denotes Interestingly, although there were no substantial differences in thrombin inhibitory activity, the high-mannose-type showed higher heparin binding affinity.
T8 1016-1228 Sentence denotes The anticoagulant activities were increased by heparin and correlated with the heparin binding affinity, resulting in the strongest anticoagulant activity being displayed in the β-form with the high-mannose-type.
T9 1229-1342 Sentence denotes In pharmacokinetic profiling, the high-mannose-type showed a much shorter plasma half-life than the complex-type.
T10 1343-1539 Sentence denotes The β-form was found to have a prolonged plasma half-life compared with the α-form for the high-mannose-type; conversely, the α-form showed a longer half-life than the β-form for the complex-type.
T11 1540-1740 Sentence denotes The present study highlights that AT physiological activities are strictly controlled not only by a core fucose at the reducing end but also by the high-mannose-type structures at the nonreducing end.
T12 1741-1913 Sentence denotes The β-form with the immature high-mannose-type appears to function as a more potent anticoagulant than the AT typically found in human plasma, once it emerges in the blood.
T1 0-135 Sentence denotes Comparison of biological activities of human antithrombins with high-mannose or complex- type nonfucosylated N-linked oligosaccharides.
T2 136-286 Sentence denotes The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics.
T3 287-473 Sentence denotes Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by changing its heparin binding affinity.
T4 474-614 Sentence denotes In human plasma, AT circulates as a mixture of the α-form bearing four oligosaccharides and the β-form lacking an oligosaccharide at Asn135.
T5 615-758 Sentence denotes However, it remains unclear how the immature high-mannose-type oligosaccharides produced by mammalian cells affect biological activities of AT.
T6 759-858 Sentence denotes Here, we succeeded in directly comparing the activities between the high-mannose and complex-types.
T7 859-1015 Sentence denotes Interestingly, although there were no substantial differences in thrombin inhibitory activity, the high-mannose-type showed higher heparin binding affinity.
T8 1016-1228 Sentence denotes The anticoagulant activities were increased by heparin and correlated with the heparin binding affinity, resulting in the strongest anticoagulant activity being displayed in the β-form with the high-mannose-type.
T9 1229-1342 Sentence denotes In pharmacokinetic profiling, the high-mannose-type showed a much shorter plasma half-life than the complex-type.
T10 1343-1539 Sentence denotes The β-form was found to have a prolonged plasma half-life compared with the α-form for the high-mannose-type; conversely, the α-form showed a longer half-life than the β-form for the complex-type.
T11 1540-1740 Sentence denotes The present study highlights that AT physiological activities are strictly controlled not only by a core fucose at the reducing end but also by the high-mannose-type structures at the nonreducing end.
T12 1741-1913 Sentence denotes The β-form with the immature high-mannose-type appears to function as a more potent anticoagulant than the AT typically found in human plasma, once it emerges in the blood.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1907-1912 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T2 1907-1912 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 69-76 FMAID:196796 denotes mannose
_T2 69-76 FMAID:82801 denotes mannose
_T3 118-134 FMAID:82742 denotes oligosaccharides
_T4 118-134 FMAID:196731 denotes oligosaccharides
_T5 166-182 FMAID:82742 denotes oligosaccharides
_T6 166-182 FMAID:196731 denotes oligosaccharides
_T7 325-341 FMAID:82742 denotes oligosaccharides
_T8 325-341 FMAID:196731 denotes oligosaccharides
_T9 384-390 FMAID:196784 denotes fucose
_T10 384-390 FMAID:82790 denotes fucose
_T11 448-455 FMAID:82839 denotes heparin
_T12 448-455 FMAID:167420 denotes heparin
_T13 483-489 FMAID:162307 denotes plasma
_T14 545-561 FMAID:196731 denotes oligosaccharides
_T15 545-561 FMAID:82742 denotes oligosaccharides
_T16 588-603 FMAID:196731 denotes oligosaccharide
_T17 588-603 FMAID:82742 denotes oligosaccharide
_T18 665-672 FMAID:82801 denotes mannose
_T19 665-672 FMAID:196796 denotes mannose
_T20 678-694 FMAID:82742 denotes oligosaccharides
_T21 678-694 FMAID:196731 denotes oligosaccharides
_T22 717-722 FMAID:169002 denotes cells
_T23 717-722 FMAID:68646 denotes cells
_T24 832-839 FMAID:82801 denotes mannose
_T25 832-839 FMAID:196796 denotes mannose
_T26 897-908 FMAID:188924 denotes substantial
_T27 963-970 FMAID:196796 denotes mannose
_T28 963-970 FMAID:82801 denotes mannose
_T29 990-997 FMAID:167420 denotes heparin
_T30 990-997 FMAID:82839 denotes heparin
_T31 1063-1070 FMAID:82839 denotes heparin
_T32 1063-1070 FMAID:167420 denotes heparin
_T33 1095-1102 FMAID:82839 denotes heparin
_T34 1095-1102 FMAID:167420 denotes heparin
_T35 1215-1222 FMAID:82801 denotes mannose
_T36 1215-1222 FMAID:196796 denotes mannose
_T37 1268-1275 FMAID:82801 denotes mannose
_T38 1268-1275 FMAID:196796 denotes mannose
_T39 1303-1309 FMAID:162307 denotes plasma
_T40 1384-1390 FMAID:162307 denotes plasma
_T41 1439-1446 FMAID:82801 denotes mannose
_T42 1439-1446 FMAID:196796 denotes mannose
_T43 1645-1651 FMAID:82790 denotes fucose
_T44 1645-1651 FMAID:196784 denotes fucose
_T45 1693-1700 FMAID:196796 denotes mannose
_T46 1693-1700 FMAID:82801 denotes mannose
_T47 1775-1782 FMAID:196796 denotes mannose
_T48 1775-1782 FMAID:82801 denotes mannose
_T49 1876-1882 FMAID:162307 denotes plasma
_T50 1907-1912 FMAID:256053 denotes blood

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 209-211 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT
T2 293-295 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT
T3 491-493 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT
T4 755-757 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT
T5 1574-1576 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT
T6 1848-1850 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 717-722 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 242-264 http://purl.obolibrary.org/obo/GO_0050819 denotes anticoagulant activity
T2 1020-1044 http://purl.obolibrary.org/obo/GO_0050819 denotes anticoagulant activities

GO-MF

Id Subject Object Predicate Lexical cue
T1 448-463 http://purl.obolibrary.org/obo/GO_0008201 denotes heparin binding
T2 990-1005 http://purl.obolibrary.org/obo/GO_0008201 denotes heparin binding
T3 1095-1110 http://purl.obolibrary.org/obo/GO_0008201 denotes heparin binding
T4 456-463 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T5 998-1005 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T6 1103-1110 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T7 456-463 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T8 998-1005 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T9 1103-1110 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T10 456-463 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T11 998-1005 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T12 1103-1110 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T13 456-463 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T14 998-1005 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T15 1103-1110 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GO-CC

Id Subject Object Predicate Lexical cue
T1 379-383 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T2 1640-1644 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T3 717-722 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 1907-1912 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 1907-1912 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T2 1907-1912 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1907-1912 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 64-76 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T2 660-672 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T3 827-839 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T4 958-970 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T5 1210-1222 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T6 1263-1275 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T7 1434-1446 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T8 1688-1700 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T9 1770-1782 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T10 448-455 http://rdf.glycoinfo.org/glycan/G54161DR denotes heparin
T11 990-997 http://rdf.glycoinfo.org/glycan/G54161DR denotes heparin
T12 1063-1070 http://rdf.glycoinfo.org/glycan/G54161DR denotes heparin
T13 1095-1102 http://rdf.glycoinfo.org/glycan/G54161DR denotes heparin

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1907-1912 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 39-44 OrganismTaxon denotes human 9606
T2 287-292 OrganismTaxon denotes Human 9606
T3 477-482 OrganismTaxon denotes human 9606
T4 1870-1875 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 483-489 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T2 1303-1309 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T3 1384-1390 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T4 1876-1882 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T5 1907-1912 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178