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PubMed:26744332 / 559-948 JSONTXT

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PubTator4TogoVar

Id Subject Object Predicate Lexical cue proteinmutation
26744332_2 246-252 ProteinMutation denotes G2019S rs34637584
26744332_5 256-262 ProteinMutation denotes R1441C rs33939927

c_corpus

Id Subject Object Predicate Lexical cue
T77 25-33 SO:0000001 denotes sequence
T82 135-154 D010300 denotes Parkinson's disease
T83 135-154 D010300 denotes Parkinson's disease
T86 174-179 PR:Q5S006 denotes LRRK2
T87 174-179 PR:000003033 denotes LRRK2
T88 174-179 PR:Q5S007 denotes LRRK2
T89 180-211 SO:0000153 denotes bacterial artificial chromosome
T90 190-200 32630 denotes artificial
T91 201-211 GO:0005694 denotes chromosome
T93 212-222 SO:0000781 denotes transgenic
T94 212-227 D055647 denotes transgenic rats
T98 274-283 SO:0000817 denotes wild-type
T99 284-289 PR:Q5S006 denotes LRRK2
T100 284-289 PR:000003033 denotes LRRK2
T101 284-289 PR:Q5S007 denotes LRRK2
T102 309-314 D006801 denotes human
T103 315-320 PR:Q5S006 denotes LRRK2
T104 315-320 PR:000003033 denotes LRRK2
T105 315-320 PR:Q5S007 denotes LRRK2
T106 357-365 SO:0000167 denotes promoter

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T3 0-389 DRI_Challenge denotes To better understand the sequence of events that lead to progressive neurophysiological deficits in vulnerable neurons and circuits in Parkinson's disease, we have generated LRRK2 bacterial artificial chromosome transgenic rats expressing either G2019S or R1441C mutant, or wild-type LRRK2, from the complete human LRRK2 genomic locus, including endogenous promoter and regulatory regions.