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PubMed:2674121 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 159-168 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T3 461-470 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE

sentences

Id Subject Object Predicate Lexical cue
T1 0-77 Sentence denotes Analysis of the structural specificity of the lactose permease toward sugars.
T2 78-153 Sentence denotes The sugar specificity properties of the lactose permease were investigated.
T3 154-255 Sentence denotes Free galactose was shown to competitively inhibit the lactose permease yielding a Ki value of 7.4 mM.
T4 256-332 Sentence denotes This value was severalfold higher than the observed Km for lactose (1.3 mM).
T5 333-424 Sentence denotes A variety of other monosaccharides also showed significant inhibition of lactose transport.
T6 425-596 Sentence denotes With regard to -OH groups along the galactose ring it appears that the relative importance is OH-3 greater than OH-4 greater than OH-6 greater than OH-2 greater than OH-1.
T7 597-729 Sentence denotes In general, galactosides with alpha-linkages exhibited significantly higher affinities compared with their beta-linked counterparts.
T8 730-862 Sentence denotes An optimal size for the aglycone portion of the galactoside was reached with aglycones containing hexose residues or a benzene ring.
T9 863-1042 Sentence denotes The preferred size of the aglycone appears to be hexose, benzene ring greater than methyl group greater than no aglycone much greater than disaccharide greater than trisaccharide.
T10 1043-1188 Sentence denotes However, neither the specific structure of the aglycone nor its relative hydrophobicity appeared to be important factors in permease recognition.
T11 1189-1434 Sentence denotes For example, the hydrophobic beta-nitrophenyl-galactosides had lower affinities compared with lactose (a beta-galactoside), whereas the alpha-nitrophenylgalactosides generally had higher affinities compared with melibiose (an alpha-galactoside).
T12 1435-1551 Sentence denotes In addition, no consistent preference was seen when considering the location of the nitro group on the benzene ring.
T13 1552-1655 Sentence denotes From this work, a model is presented which depicts the binding of galactosides to the lactose permease.
T1 0-77 Sentence denotes Analysis of the structural specificity of the lactose permease toward sugars.
T2 78-153 Sentence denotes The sugar specificity properties of the lactose permease were investigated.
T3 154-255 Sentence denotes Free galactose was shown to competitively inhibit the lactose permease yielding a Ki value of 7.4 mM.
T4 256-332 Sentence denotes This value was severalfold higher than the observed Km for lactose (1.3 mM).
T5 333-424 Sentence denotes A variety of other monosaccharides also showed significant inhibition of lactose transport.
T6 425-596 Sentence denotes With regard to -OH groups along the galactose ring it appears that the relative importance is OH-3 greater than OH-4 greater than OH-6 greater than OH-2 greater than OH-1.
T7 597-729 Sentence denotes In general, galactosides with alpha-linkages exhibited significantly higher affinities compared with their beta-linked counterparts.
T8 730-862 Sentence denotes An optimal size for the aglycone portion of the galactoside was reached with aglycones containing hexose residues or a benzene ring.
T9 863-1042 Sentence denotes The preferred size of the aglycone appears to be hexose, benzene ring greater than methyl group greater than no aglycone much greater than disaccharide greater than trisaccharide.
T10 1043-1188 Sentence denotes However, neither the specific structure of the aglycone nor its relative hydrophobicity appeared to be important factors in permease recognition.
T11 1189-1434 Sentence denotes For example, the hydrophobic beta-nitrophenyl-galactosides had lower affinities compared with lactose (a beta-galactoside), whereas the alpha-nitrophenylgalactosides generally had higher affinities compared with melibiose (an alpha-galactoside).
T12 1435-1551 Sentence denotes In addition, no consistent preference was seen when considering the location of the nitro group on the benzene ring.
T13 1552-1655 Sentence denotes From this work, a model is presented which depicts the binding of galactosides to the lactose permease.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 159-168 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T2 159-168 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T3 461-470 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T4 461-470 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 46-53 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T2 118-125 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T3 208-215 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T4 315-322 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T5 406-413 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T6 1283-1290 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T7 1401-1410 Glycan denotes melibiose https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II
T8 1638-1645 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 234-238 Phenotype denotes a Ki HP:0001919

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 46-53 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T2 118-125 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T3 208-215 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T4 315-322 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T5 406-413 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T6 1283-1290 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T7 1401-1410 Glycan denotes melibiose https://api.glycosmos.org/wurcs2image/latest/png/binary/G66481II
T8 1638-1645 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-77 Sentence denotes Analysis of the structural specificity of the lactose permease toward sugars.
T2 78-153 Sentence denotes The sugar specificity properties of the lactose permease were investigated.
T3 154-255 Sentence denotes Free galactose was shown to competitively inhibit the lactose permease yielding a Ki value of 7.4 mM.
T4 256-332 Sentence denotes This value was severalfold higher than the observed Km for lactose (1.3 mM).
T5 333-424 Sentence denotes A variety of other monosaccharides also showed significant inhibition of lactose transport.
T6 425-596 Sentence denotes With regard to -OH groups along the galactose ring it appears that the relative importance is OH-3 greater than OH-4 greater than OH-6 greater than OH-2 greater than OH-1.
T7 597-729 Sentence denotes In general, galactosides with alpha-linkages exhibited significantly higher affinities compared with their beta-linked counterparts.
T8 730-862 Sentence denotes An optimal size for the aglycone portion of the galactoside was reached with aglycones containing hexose residues or a benzene ring.
T9 863-1042 Sentence denotes The preferred size of the aglycone appears to be hexose, benzene ring greater than methyl group greater than no aglycone much greater than disaccharide greater than trisaccharide.
T10 1043-1188 Sentence denotes However, neither the specific structure of the aglycone nor its relative hydrophobicity appeared to be important factors in permease recognition.
T11 1189-1434 Sentence denotes For example, the hydrophobic beta-nitrophenyl-galactosides had lower affinities compared with lactose (a beta-galactoside), whereas the alpha-nitrophenylgalactosides generally had higher affinities compared with melibiose (an alpha-galactoside).
T12 1435-1551 Sentence denotes In addition, no consistent preference was seen when considering the location of the nitro group on the benzene ring.
T13 1552-1655 Sentence denotes From this work, a model is presented which depicts the binding of galactosides to the lactose permease.