PubMed:26715205 / 1695-2211 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/26715205","sourcedb":"PubMed","sourceid":"26715205","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/26715205","text":"We present a method to assess the migration of epicardial cells in an in vitro assay, wherein the migration of epicardial cells from a donor heart onto the myocardium of a recipient heart in co-culture is monitored and scored. The donor and recipient hearts can be independently manipulated, using either genetic tools or pharmacological agents. This allows flexibility in experimental design for determining the role that target genes/signaling pathways in specific cell types may have on epicardial cell migration.","tracks":[{"project":"GoldHamster","denotations":[{"id":"T58","span":{"begin":135,"end":140},"obj":"SO:0000163"},{"id":"T57","span":{"begin":135,"end":140},"obj":"CHEBI:17499"},{"id":"T59","span":{"begin":135,"end":140},"obj":"CHEBI:17891"},{"id":"T60","span":{"begin":156,"end":166},"obj":"UBERON:0002349"},{"id":"T62","span":{"begin":231,"end":236},"obj":"SO:0000163"},{"id":"T61","span":{"begin":231,"end":236},"obj":"CHEBI:17499"},{"id":"T63","span":{"begin":231,"end":236},"obj":"CHEBI:17891"},{"id":"T64","span":{"begin":436,"end":445},"obj":"GO:0023052"},{"id":"T65","span":{"begin":501,"end":515},"obj":"GO:0016477"}],"attributes":[{"subj":"T58","pred":"source","obj":"GoldHamster"},{"subj":"T57","pred":"source","obj":"GoldHamster"},{"subj":"T59","pred":"source","obj":"GoldHamster"},{"subj":"T60","pred":"source","obj":"GoldHamster"},{"subj":"T62","pred":"source","obj":"GoldHamster"},{"subj":"T61","pred":"source","obj":"GoldHamster"},{"subj":"T63","pred":"source","obj":"GoldHamster"},{"subj":"T64","pred":"source","obj":"GoldHamster"},{"subj":"T65","pred":"source","obj":"GoldHamster"}]},{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T3","span":{"begin":0,"end":516},"obj":"CONCLUSIONS"}],"attributes":[{"subj":"T3","pred":"source","obj":"PubMed_Structured_Abstracts"}]},{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T19","span":{"begin":0,"end":2},"obj":"CVCL_5M23|Cancer_cell_line|Mesocricetus auratus"},{"id":"T20","span":{"begin":11,"end":12},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T21","span":{"begin":67,"end":69},"obj":"CVCL_8754|Cancer_cell_line|Homo sapiens"},{"id":"T22","span":{"begin":67,"end":69},"obj":"CVCL_H241|Cancer_cell_line|Homo sapiens"},{"id":"T23","span":{"begin":133,"end":134},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T24","span":{"begin":170,"end":171},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T25","span":{"begin":191,"end":193},"obj":"CVCL_J653|Cancer_cell_line|Homo sapiens"},{"id":"T26","span":{"begin":478,"end":481},"obj":"CVCL_E773|Transformed_cell_line|Homo sapiens"}],"attributes":[{"subj":"T19","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T20","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T21","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T22","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T23","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T24","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T25","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T26","pred":"source","obj":"Goldhamster2_Cellosaurus"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"GoldHamster","color":"#a6ec93","default":true},{"id":"PubMed_Structured_Abstracts","color":"#ec93c0"},{"id":"Goldhamster2_Cellosaurus","color":"#93daec"}]}]}}