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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-146 Sentence denotes The valine and lysine residues in the conserved FxVTxK motif are important for the function of phylogenetically distant plant cellulose synthases.
TextSentencer_T2 147-275 Sentence denotes Cellulose synthases (CESAs) synthesize the β-1,4-glucan chains that coalesce to form cellulose microfibrils in plant cell walls.
TextSentencer_T3 276-385 Sentence denotes In addition to a large cytosolic (catalytic) domain, CESAs have eight predicted transmembrane helices (TMHs).
TextSentencer_T4 386-508 Sentence denotes However, analogous to the structure of BcsA, a bacterial CESA, predicted TMH5 in CESA may instead be an interfacial helix.
TextSentencer_T5 509-648 Sentence denotes This would place the conserved FxVTxK motif in the plant cell cytosol where it could function as a substrate-gating loop as occurs in BcsA.
TextSentencer_T6 649-874 Sentence denotes To define the functional importance of the CESA region containing FxVTxK, we tested five parallel mutations in Arabidopsis thaliana CESA1 and Physcomitrella patens CESA5 in complementation assays of the relevant cesa mutants.
TextSentencer_T7 875-986 Sentence denotes In both organisms, the substitution of the valine or lysine residues in FxVTxK severely affected CESA function.
TextSentencer_T8 987-1109 Sentence denotes In Arabidopsis roots, both changes were correlated with lower cellulose anisotropy, as revealed by Pontamine Fast Scarlet.
TextSentencer_T9 1110-1299 Sentence denotes Analysis of hypocotyl inner cell wall layers by atomic force microscopy showed that two altered versions of Atcesa1 could rescue cell wall phenotypes observed in the mutant background line.
TextSentencer_T10 1300-1415 Sentence denotes Overall, the data show that the FxVTxK motif is functionally important in two phylogenetically distant plant CESAs.
TextSentencer_T11 1416-1679 Sentence denotes The results show that Physcomitrella provides an efficient model for assessing the effects of engineered CESA mutations affecting primary cell wall synthesis and that diverse testing systems can lead to nuanced insights into CESA structure-function relationships.
TextSentencer_T12 1680-1847 Sentence denotes Although CESA membrane topology needs to be experimentally determined, the results support the possibility that the FxVTxK region functions similarly in CESA and BcsA.
T1 0-146 Sentence denotes The valine and lysine residues in the conserved FxVTxK motif are important for the function of phylogenetically distant plant cellulose synthases.
T2 147-275 Sentence denotes Cellulose synthases (CESAs) synthesize the β-1,4-glucan chains that coalesce to form cellulose microfibrils in plant cell walls.
T3 276-385 Sentence denotes In addition to a large cytosolic (catalytic) domain, CESAs have eight predicted transmembrane helices (TMHs).
T4 386-508 Sentence denotes However, analogous to the structure of BcsA, a bacterial CESA, predicted TMH5 in CESA may instead be an interfacial helix.
T5 509-648 Sentence denotes This would place the conserved FxVTxK motif in the plant cell cytosol where it could function as a substrate-gating loop as occurs in BcsA.
T6 649-874 Sentence denotes To define the functional importance of the CESA region containing FxVTxK, we tested five parallel mutations in Arabidopsis thaliana CESA1 and Physcomitrella patens CESA5 in complementation assays of the relevant cesa mutants.
T7 875-986 Sentence denotes In both organisms, the substitution of the valine or lysine residues in FxVTxK severely affected CESA function.
T8 987-1299 Sentence denotes In Arabidopsis roots, both changes were correlated with lower cellulose anisotropy, as revealed by Pontamine Fast Scarlet. Analysis of hypocotyl inner cell wall layers by atomic force microscopy showed that two altered versions of Atcesa1 could rescue cell wall phenotypes observed in the mutant background line.
T9 1300-1415 Sentence denotes Overall, the data show that the FxVTxK motif is functionally important in two phylogenetically distant plant CESAs.
T10 1416-1679 Sentence denotes The results show that Physcomitrella provides an efficient model for assessing the effects of engineered CESA mutations affecting primary cell wall synthesis and that diverse testing systems can lead to nuanced insights into CESA structure-function relationships.
T11 1680-1847 Sentence denotes Although CESA membrane topology needs to be experimentally determined, the results support the possibility that the FxVTxK region functions similarly in CESA and BcsA.
T1 0-146 Sentence denotes The valine and lysine residues in the conserved FxVTxK motif are important for the function of phylogenetically distant plant cellulose synthases.
T2 147-275 Sentence denotes Cellulose synthases (CESAs) synthesize the β-1,4-glucan chains that coalesce to form cellulose microfibrils in plant cell walls.
T3 276-385 Sentence denotes In addition to a large cytosolic (catalytic) domain, CESAs have eight predicted transmembrane helices (TMHs).
T4 386-508 Sentence denotes However, analogous to the structure of BcsA, a bacterial CESA, predicted TMH5 in CESA may instead be an interfacial helix.
T5 509-648 Sentence denotes This would place the conserved FxVTxK motif in the plant cell cytosol where it could function as a substrate-gating loop as occurs in BcsA.
T6 649-874 Sentence denotes To define the functional importance of the CESA region containing FxVTxK, we tested five parallel mutations in Arabidopsis thaliana CESA1 and Physcomitrella patens CESA5 in complementation assays of the relevant cesa mutants.
T7 875-986 Sentence denotes In both organisms, the substitution of the valine or lysine residues in FxVTxK severely affected CESA function.
T8 987-1109 Sentence denotes In Arabidopsis roots, both changes were correlated with lower cellulose anisotropy, as revealed by Pontamine Fast Scarlet.
T9 1110-1299 Sentence denotes Analysis of hypocotyl inner cell wall layers by atomic force microscopy showed that two altered versions of Atcesa1 could rescue cell wall phenotypes observed in the mutant background line.
T10 1300-1415 Sentence denotes Overall, the data show that the FxVTxK motif is functionally important in two phylogenetically distant plant CESAs.
T11 1416-1679 Sentence denotes The results show that Physcomitrella provides an efficient model for assessing the effects of engineered CESA mutations affecting primary cell wall synthesis and that diverse testing systems can lead to nuanced insights into CESA structure-function relationships.
T12 1680-1847 Sentence denotes Although CESA membrane topology needs to be experimentally determined, the results support the possibility that the FxVTxK region functions similarly in CESA and BcsA.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 4-10 FMAID:82766 denotes valine
_T2 4-10 FMAID:196755 denotes valine
_T3 15-21 FMAID:82758 denotes lysine
_T4 15-21 FMAID:196747 denotes lysine
_T5 120-125 FMAID:214748 denotes plant
_T6 126-135 FMAID:196737 denotes cellulose
_T7 126-135 FMAID:82748 denotes cellulose
_T8 147-156 FMAID:82748 denotes Cellulose
_T9 147-156 FMAID:196737 denotes Cellulose
_T10 232-241 FMAID:82748 denotes cellulose
_T11 232-241 FMAID:196737 denotes cellulose
_T12 258-263 FMAID:214748 denotes plant
_T13 502-507 FMAID:161427 denotes helix
_T14 502-507 FMAID:60992 denotes helix
_T15 560-565 FMAID:214748 denotes plant
_T16 571-578 FMAID:256055 denotes cytosol
_T17 726-732 FMAID:178661 denotes tested
_T18 883-892 FMAID:67498 denotes organisms
_T19 883-892 FMAID:166081 denotes organisms
_T20 918-924 FMAID:82766 denotes valine
_T21 918-924 FMAID:196755 denotes valine
_T22 928-934 FMAID:196747 denotes lysine
_T23 928-934 FMAID:82758 denotes lysine
_T24 1049-1058 FMAID:82748 denotes cellulose
_T25 1049-1058 FMAID:196737 denotes cellulose
_T26 1132-1142 FMAID:166606 denotes inner cell
_T27 1403-1408 FMAID:214748 denotes plant
_T28 1591-1598 FMAID:178661 denotes testing

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 370-377 http://purl.bioontology.org/ontology/NCBITAXON/53324 denotes helices
T2 502-507 http://purl.bioontology.org/ontology/NCBITAXON/6534 denotes helix
T3 738-746 http://purl.bioontology.org/ontology/NCBITAXON/871272 denotes parallel
T4 760-771 http://purl.bioontology.org/ontology/NCBITAXON/3701 denotes Arabidopsis
T5 760-771 http://purl.bioontology.org/ontology/NCBITAXON/1150658 denotes Arabidopsis
T6 760-780 http://purl.bioontology.org/ontology/NCBITAXON/3702 denotes Arabidopsis thaliana
T7 772-780 http://purl.bioontology.org/ontology/NCBITAXON/96513 denotes thaliana
T8 791-805 http://purl.bioontology.org/ontology/NCBITAXON/3217 denotes Physcomitrella
T9 791-812 http://purl.bioontology.org/ontology/NCBITAXON/3218 denotes Physcomitrella patens
T10 990-1001 http://purl.bioontology.org/ontology/NCBITAXON/3701 denotes Arabidopsis
T11 990-1001 http://purl.bioontology.org/ontology/NCBITAXON/1150658 denotes Arabidopsis
T12 1438-1452 http://purl.bioontology.org/ontology/NCBITAXON/3217 denotes Physcomitrella

GO-BP

Id Subject Object Predicate Lexical cue
T1 1096-1100 http://purl.obolibrary.org/obo/GO_0033867 denotes Fast
T2 1554-1573 http://purl.obolibrary.org/obo/GO_0009834 denotes cell wall synthesis
T3 1554-1573 http://purl.obolibrary.org/obo/GO_0006038 denotes cell wall synthesis
T4 1554-1573 http://purl.obolibrary.org/obo/GO_0009833 denotes cell wall synthesis
T5 1554-1573 http://purl.obolibrary.org/obo/GO_0044038 denotes cell wall synthesis
T6 1554-1573 http://purl.obolibrary.org/obo/GO_0051278 denotes cell wall synthesis
T7 1554-1573 http://purl.obolibrary.org/obo/GO_0070592 denotes cell wall synthesis
T8 1554-1573 http://purl.obolibrary.org/obo/GO_0000032 denotes cell wall synthesis
T9 1554-1573 http://purl.obolibrary.org/obo/GO_0009273 denotes cell wall synthesis
T10 1554-1573 http://purl.obolibrary.org/obo/GO_0009832 denotes cell wall synthesis
T11 1554-1573 http://purl.obolibrary.org/obo/GO_0043164 denotes cell wall synthesis
T12 1554-1573 http://purl.obolibrary.org/obo/GO_0031506 denotes cell wall synthesis
T13 1564-1573 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

GO-CC

Id Subject Object Predicate Lexical cue
T1 232-254 http://purl.obolibrary.org/obo/GO_0009549 denotes cellulose microfibrils
T2 242-254 http://purl.obolibrary.org/obo/GO_0001527 denotes microfibrils
T3 258-274 http://purl.obolibrary.org/obo/GO_0009505 denotes plant cell walls
T4 264-268 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 566-570 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6 1138-1142 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T7 1239-1243 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T8 1554-1558 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T9 264-274 http://purl.obolibrary.org/obo/GO_0005618 denotes cell walls
T10 1138-1147 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall
T11 1239-1248 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall
T12 1554-1563 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall
T13 299-308 http://purl.obolibrary.org/obo/GO_0005829 denotes cytosolic
T14 571-578 http://purl.obolibrary.org/obo/GO_0005829 denotes cytosol
T15 356-369 http://purl.obolibrary.org/obo/GO_0016021 denotes transmembrane
T16 356-369 http://purl.obolibrary.org/obo/GO_0044214 denotes transmembrane
T17 1546-1563 http://purl.obolibrary.org/obo/GO_0009530 denotes primary cell wall
T18 1694-1702 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 502-507 http://purl.obolibrary.org/obo/UBERON_0002488 denotes helix
T2 883-892 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organisms

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 1591-1606 http://purl.obolibrary.org/obo/MAT_0000275 denotes testing systems

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 126-135 http://rdf.glycoinfo.org/glycan/G00025MO denotes cellulose
T2 232-241 http://rdf.glycoinfo.org/glycan/G00025MO denotes cellulose
T3 1049-1058 http://rdf.glycoinfo.org/glycan/G00025MO denotes cellulose

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 883-892 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organisms
PD-UBERON-AE-B_T2 502-507 http://purl.obolibrary.org/obo/UBERON_0002488 denotes helix

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 760-780 OrganismTaxon denotes Arabidopsis thaliana 3702
T2 791-812 OrganismTaxon denotes Physcomitrella patens 3218
T3 861-865 OrganismTaxon denotes cesa 889674
T4 990-1001 OrganismTaxon denotes Arabidopsis 3701

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 356-369 Body_part denotes transmembrane http://purl.obolibrary.org/obo/GO_0016020
T2 502-507 Body_part denotes helix http://purl.obolibrary.org/obo/UBERON_0002488
T3 571-578 Body_part denotes cytosol http://purl.obolibrary.org/obo/GO_0005829
T4 883-892 Body_part denotes organisms http://purl.obolibrary.org/obo/UBERON_0000468
T5 1143-1147 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060
T6 1244-1248 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060
T7 1559-1563 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060
T8 1694-1702 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158