PubMed:26528898 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	0-12	UBERON:0014402	denotes	Sex-specific
T2	13-32	GO:0001666	denotes	response to hypoxia
T3	25-32	D000860	denotes	hypoxia
T4	25-32	D000860	denotes	hypoxia
T5	46-55	UBERON:0002298	denotes	brainstem
T14	73-87	D014982	denotes	Xenopus laevis
T15	73-87	8355	denotes	Xenopus laevis
T16	127-134	D000860	denotes	hypoxia
T17	127-134	D000860	denotes	hypoxia
T18	311-322	D014714	denotes	vertebrates
T19	340-352	UBERON:0014402	denotes	sex-specific
T20	371-378	D000860	denotes	hypoxia
T21	371-378	D000860	denotes	hypoxia
T22	385-390	UBERON:0007023	denotes	adult
T23	399-408	UBERON:0002298	denotes	brainstem
T32	426-440	D014982	denotes	Xenopus laevis
T33	426-440	8355	denotes	Xenopus laevis
T34	460-463	CVCL_E777	denotes	min
T35	487-491	PR:Q9M591	denotes	aCSF
T36	497-501	CHEBI:29275	denotes	N2/2
T37	497-501	CHEBI:29277	denotes	N2/2
T38	503-506	CHEBI:29325	denotes	CO2
T39	503-506	CHEBI:48828	denotes	CO2
T40	503-506	CHEBI:16526	denotes	CO2
T41	503-506	CHEBI:29334	denotes	CO2
T42	588-597	GO:0007585	denotes	breathing
T43	718-728	UBERON:0004704	denotes	depression
T44	739-742	CVCL_E777	denotes	min
T45	858-868	D000663	denotes	amphibians
T46	950-961	D014714	denotes	vertebrates

Id	Subject	Object	Predicate	Lexical cue
T1	89-170	DRI_Outcome	denotes	Respiratory reflexes and tolerance to hypoxia show significant sexual dimorphism.
T2	171-248	DRI_Background	denotes	However, the data supporting this notion originates exclusively from mammals.
T3	249-441	DRI_Approach	denotes	To determine whether this concept is limited to this group of vertebrates, we examined the sex-specific response to acute hypoxia in an adult reduced brainstem preparation from Xenopus laevis.
T4	442-630	DRI_Outcome	denotes	Within the first 5min of exposure to hypoxic aCSF (98% N2/2% CO2), recordings of respiratory-related activity show a stronger increase in fictive breathing frequency in males than females.
T5	631-772	DRI_Approach	denotes	This initial response was followed by a decrease in respiratory-related activity; this depression occurred 6min sooner in males than females.
T6	773-981	DRI_Background	denotes	These results represent new evidences of sexual dimorphism in respiratory control in amphibians and provide potential insight in understanding the homology with other groups of vertebrates, including mammals.

Id	Subject	Object	Predicate	Lexical cue
T1	36-37	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T2	324-326	CVCL_5M23\|Cancer_cell_line\|Mesocricetus auratus	denotes	we
T3	382-384	CVCL_8754\|Cancer_cell_line\|Homo sapiens	denotes	an
T4	382-384	CVCL_H241\|Cancer_cell_line\|Homo sapiens	denotes	an
T5	493-495	CVCL_ZS44\|Transformed_cell_line\|Homo sapiens	denotes	98
T6	497-501	CVCL_8965\|Hybridoma\|Cricetulus migratorius,Mus musculus	denotes	N2/2
T7	497-499	CVCL_5942\|Cancer_cell_line\|Homo sapiens	denotes	N2
T8	497-499	CVCL_ZU48\|Transformed_cell_line\|Homo sapiens	denotes	N2
T9	543-551	CVCL_C410\|Hybridoma\|Mus musculus	denotes	activity
T10	557-558	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T11	669-670	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T12	703-711	CVCL_C410\|Hybridoma\|Mus musculus	denotes	activity