PubMed:26513453 JSONTXT

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":178},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":179,"end":189},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":190,"end":325},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":326,"end":339},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":340,"end":367},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":368,"end":515},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":516,"end":619},"obj":"Sentence"},{"id":"TextSentencer_T8","span":{"begin":620,"end":678},"obj":"Sentence"},{"id":"TextSentencer_T9","span":{"begin":679,"end":686},"obj":"Sentence"},{"id":"TextSentencer_T10","span":{"begin":687,"end":782},"obj":"Sentence"},{"id":"TextSentencer_T11","span":{"begin":783,"end":884},"obj":"Sentence"},{"id":"TextSentencer_T12","span":{"begin":885,"end":986},"obj":"Sentence"},{"id":"TextSentencer_T13","span":{"begin":987,"end":1082},"obj":"Sentence"},{"id":"TextSentencer_T14","span":{"begin":1083,"end":1290},"obj":"Sentence"},{"id":"TextSentencer_T15","span":{"begin":1291,"end":1431},"obj":"Sentence"},{"id":"TextSentencer_T16","span":{"begin":1432,"end":1443},"obj":"Sentence"},{"id":"TextSentencer_T17","span":{"begin":1444,"end":1541},"obj":"Sentence"},{"id":"TextSentencer_T18","span":{"begin":1542,"end":1610},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":178},"obj":"Sentence"},{"id":"T2","span":{"begin":179,"end":189},"obj":"Sentence"},{"id":"T3","span":{"begin":190,"end":325},"obj":"Sentence"},{"id":"T4","span":{"begin":326,"end":339},"obj":"Sentence"},{"id":"T5","span":{"begin":340,"end":367},"obj":"Sentence"},{"id":"T6","span":{"begin":368,"end":515},"obj":"Sentence"},{"id":"T7","span":{"begin":516,"end":619},"obj":"Sentence"},{"id":"T8","span":{"begin":620,"end":678},"obj":"Sentence"},{"id":"T9","span":{"begin":679,"end":686},"obj":"Sentence"},{"id":"T10","span":{"begin":687,"end":782},"obj":"Sentence"},{"id":"T11","span":{"begin":783,"end":884},"obj":"Sentence"},{"id":"T12","span":{"begin":885,"end":986},"obj":"Sentence"},{"id":"T13","span":{"begin":987,"end":1082},"obj":"Sentence"},{"id":"T14","span":{"begin":1083,"end":1290},"obj":"Sentence"},{"id":"T15","span":{"begin":1291,"end":1431},"obj":"Sentence"},{"id":"T16","span":{"begin":1432,"end":1443},"obj":"Sentence"},{"id":"T17","span":{"begin":1444,"end":1541},"obj":"Sentence"},{"id":"T18","span":{"begin":1542,"end":1610},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Isolated proteinuria is a risk factor for pre-eclampsia: a retrospective analysis of the maternal and neonatal outcomes in women presenting with isolated gestational proteinuria.\nOBJECTIVE: To examine maternal and neonatal outcomes of isolated proteinuria and define maternal characteristics for progression to pre-eclampsia.\nSTUDY DESIGN: Retrospective cohort study. Data from all hospitalized pregnant women between 2009 and 2014 with new onset isolated proteinuria of over 300 mg/24 h at admission were obtained. Follow-up was performed from the time of admission to the hospital to the time of discharge postpartum. Obstetrical, maternal and neonatal outcomes were obtained.\nRESULT: Ninety-five pregnant women diagnosed with new onset isolated proteinuria were followed to term. Thirteen women developed pre-eclampsia during pregnancy and eight developed pre-eclampsia postpartum. Maternal characteristics for progression to pre-eclampsia were greater maximal values of proteinuria. Earlier pre-eclampsia onset was associated with early-onset proteinuria and multiple gestation. Although greater values of proteinuria were associated with increased risk for intrauterine growth restriction and lower Apgar scores, maternal outcome was favorable, regardless of pre-eclampsia progression. Isolated proteinuria progressing to pre-eclampsia was associated with late pre-eclampsia onset and favorable maternal and neonatal outcomes.\nCONCLUSION: A significant proportion of women with new onset isolated proteinuria will develop pre-eclampsia. In these women, close follow-up is recommended until after delivery."}

{"project":"Preeclampsia","denotations":[{"id":"PD-Preeclampsia-B_T1","span":{"begin":42,"end":55},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T2","span":{"begin":311,"end":324},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T3","span":{"begin":808,"end":821},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T4","span":{"begin":859,"end":872},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T5","span":{"begin":929,"end":942},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T6","span":{"begin":995,"end":1008},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T7","span":{"begin":1264,"end":1277},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T8","span":{"begin":1327,"end":1340},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T9","span":{"begin":1366,"end":1379},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T10","span":{"begin":1527,"end":1540},"obj":"ORPHA:275555"}],"namespaces":[{"prefix":"ORPHA","uri":"www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN\u0026Expert="}],"text":"Isolated proteinuria is a risk factor for pre-eclampsia: a retrospective analysis of the maternal and neonatal outcomes in women presenting with isolated gestational proteinuria.\nOBJECTIVE: To examine maternal and neonatal outcomes of isolated proteinuria and define maternal characteristics for progression to pre-eclampsia.\nSTUDY DESIGN: Retrospective cohort study. Data from all hospitalized pregnant women between 2009 and 2014 with new onset isolated proteinuria of over 300 mg/24 h at admission were obtained. Follow-up was performed from the time of admission to the hospital to the time of discharge postpartum. Obstetrical, maternal and neonatal outcomes were obtained.\nRESULT: Ninety-five pregnant women diagnosed with new onset isolated proteinuria were followed to term. Thirteen women developed pre-eclampsia during pregnancy and eight developed pre-eclampsia postpartum. Maternal characteristics for progression to pre-eclampsia were greater maximal values of proteinuria. Earlier pre-eclampsia onset was associated with early-onset proteinuria and multiple gestation. Although greater values of proteinuria were associated with increased risk for intrauterine growth restriction and lower Apgar scores, maternal outcome was favorable, regardless of pre-eclampsia progression. Isolated proteinuria progressing to pre-eclampsia was associated with late pre-eclampsia onset and favorable maternal and neonatal outcomes.\nCONCLUSION: A significant proportion of women with new onset isolated proteinuria will develop pre-eclampsia. In these women, close follow-up is recommended until after delivery."}

{"project":"Preeclampsia-compare","denotations":[{"id":"PD-Preeclampsia-B_T1","span":{"begin":42,"end":55},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T2","span":{"begin":311,"end":324},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T3","span":{"begin":808,"end":821},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T4","span":{"begin":859,"end":872},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T5","span":{"begin":929,"end":942},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T6","span":{"begin":995,"end":1008},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T7","span":{"begin":1264,"end":1277},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T8","span":{"begin":1327,"end":1340},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T9","span":{"begin":1366,"end":1379},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T10","span":{"begin":1527,"end":1540},"obj":"ORPHA:275555"}],"namespaces":[{"prefix":"ORPHA","uri":"www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN\u0026Expert="}],"text":"Isolated proteinuria is a risk factor for pre-eclampsia: a retrospective analysis of the maternal and neonatal outcomes in women presenting with isolated gestational proteinuria.\nOBJECTIVE: To examine maternal and neonatal outcomes of isolated proteinuria and define maternal characteristics for progression to pre-eclampsia.\nSTUDY DESIGN: Retrospective cohort study. Data from all hospitalized pregnant women between 2009 and 2014 with new onset isolated proteinuria of over 300 mg/24 h at admission were obtained. Follow-up was performed from the time of admission to the hospital to the time of discharge postpartum. Obstetrical, maternal and neonatal outcomes were obtained.\nRESULT: Ninety-five pregnant women diagnosed with new onset isolated proteinuria were followed to term. Thirteen women developed pre-eclampsia during pregnancy and eight developed pre-eclampsia postpartum. Maternal characteristics for progression to pre-eclampsia were greater maximal values of proteinuria. Earlier pre-eclampsia onset was associated with early-onset proteinuria and multiple gestation. Although greater values of proteinuria were associated with increased risk for intrauterine growth restriction and lower Apgar scores, maternal outcome was favorable, regardless of pre-eclampsia progression. Isolated proteinuria progressing to pre-eclampsia was associated with late pre-eclampsia onset and favorable maternal and neonatal outcomes.\nCONCLUSION: A significant proportion of women with new onset isolated proteinuria will develop pre-eclampsia. In these women, close follow-up is recommended until after delivery."}