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PubMed:2644988 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-118 Sentence denotes Basophils (Bsp-1+) derive from the leukemic clone in human myeloid leukemias involving the chromosome breakpoint 9q34.
TextSentencer_T2 119-418 Sentence denotes The monoclonal antibody (MoAb) Bsp-1 was used to purify basophilic cells from leukemic blood of five patients with Philadelphia chromosome (Ph') positive chronic myeloid leukemia (CML) and two patients with acute myeloid leukemia (AML) characterized by the chromosomal translocation t(6;9)(p23;q34).
TextSentencer_T3 419-635 Sentence denotes When cultured, Bsp-1 positive cells from all CML and AML patients showed the same clonal karyotype changes observed in diagnostic buffy coat preparations, indicating that the basophilic cells were of leukemic origin.
TextSentencer_T4 636-824 Sentence denotes In contrast, T lymphocytes from four of five CML patients cultured in the presence of interleukin-2 (IL-2) showed a normal karyotype and were therefore not derived from the leukemic clone.
TextSentencer_T5 825-1025 Sentence denotes Bsp-1 staining correlated with toluidine blue-positive basophils in chronic phase CML and with toluidine blue-negative blast cells expressing an immature myeloid phenotype in blast crisis CML and AML.
TextSentencer_T6 1026-1209 Sentence denotes Chromosome in situ hybridization showed that the ABL oncogene was translocated from chromosome 9 to chromosome 22 in the CML patients but remained on chromosome 9 in the AML patients.
TextSentencer_T7 1210-1333 Sentence denotes These results indicate that the breakpoint at 9q34 in CML is 5' of ABL, whereas the breakpoint at 9q34 in AML is 3' of ABL.
TextSentencer_T8 1334-1528 Sentence denotes Field inversion gel electrophoresis showed that the 9q34 breakpoint was not within 200 kb 3' of ABL in one of the AML patients, nor was there any rearrangement of the PIM oncogene locus at 6p21.
T1 0-118 Sentence denotes Basophils (Bsp-1+) derive from the leukemic clone in human myeloid leukemias involving the chromosome breakpoint 9q34.
T2 119-418 Sentence denotes The monoclonal antibody (MoAb) Bsp-1 was used to purify basophilic cells from leukemic blood of five patients with Philadelphia chromosome (Ph') positive chronic myeloid leukemia (CML) and two patients with acute myeloid leukemia (AML) characterized by the chromosomal translocation t(6;9)(p23;q34).
T3 419-635 Sentence denotes When cultured, Bsp-1 positive cells from all CML and AML patients showed the same clonal karyotype changes observed in diagnostic buffy coat preparations, indicating that the basophilic cells were of leukemic origin.
T4 636-824 Sentence denotes In contrast, T lymphocytes from four of five CML patients cultured in the presence of interleukin-2 (IL-2) showed a normal karyotype and were therefore not derived from the leukemic clone.
T5 825-1025 Sentence denotes Bsp-1 staining correlated with toluidine blue-positive basophils in chronic phase CML and with toluidine blue-negative blast cells expressing an immature myeloid phenotype in blast crisis CML and AML.
T6 1026-1209 Sentence denotes Chromosome in situ hybridization showed that the ABL oncogene was translocated from chromosome 9 to chromosome 22 in the CML patients but remained on chromosome 9 in the AML patients.
T7 1210-1333 Sentence denotes These results indicate that the breakpoint at 9q34 in CML is 5' of ABL, whereas the breakpoint at 9q34 in AML is 3' of ABL.
T8 1334-1528 Sentence denotes Field inversion gel electrophoresis showed that the 9q34 breakpoint was not within 200 kb 3' of ABL in one of the AML patients, nor was there any rearrangement of the PIM oncogene locus at 6p21.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 825-830 gene:100131137 denotes Bsp-1
T1 893-910 disease:C0023474 denotes chronic phase CML
T2 825-830 gene:4086 denotes Bsp-1
T3 893-910 disease:C0023474 denotes chronic phase CML
T4 825-830 gene:100131137 denotes Bsp-1
T5 1000-1012 disease:C0005699 denotes blast crisis
T6 825-830 gene:4086 denotes Bsp-1
T7 1000-1012 disease:C0005699 denotes blast crisis
T8 825-830 gene:100131137 denotes Bsp-1
T9 1021-1024 disease:C0023467 denotes AML
T10 825-830 gene:4086 denotes Bsp-1
T11 1021-1024 disease:C0023467 denotes AML
R1 T0 T1 associated_with Bsp-1,chronic phase CML
R2 T2 T3 associated_with Bsp-1,chronic phase CML
R3 T4 T5 associated_with Bsp-1,blast crisis
R4 T6 T7 associated_with Bsp-1,blast crisis
R5 T8 T9 associated_with Bsp-1,AML
R6 T10 T11 associated_with Bsp-1,AML

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 273-297 HP_0005506 denotes chronic myeloid leukemia
T2 281-297 HP_0012324 denotes myeloid leukemia
T3 289-297 HP_0001909 denotes leukemia
T4 326-348 HP_0004808 denotes acute myeloid leukemia
T5 332-348 HP_0012324 denotes myeloid leukemia
T6 340-348 HP_0001909 denotes leukemia

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T284 11-16 gene:100131137 denotes Bsp-1
T285 59-76 disease:C0023470 denotes myeloid leukemias
T286 150-155 gene:100131137 denotes Bsp-1
T287 893-910 disease:C0023474 denotes chronic phase CML
T288 1000-1012 disease:C0005699 denotes blast crisis
T289 1013-1016 disease:C0023473 denotes CML
T290 1021-1024 disease:C0023467 denotes AML
T291 1277-1280 gene:25 denotes ABL
T292 1264-1267 disease:C0023473 denotes CML
T293 1329-1332 gene:25 denotes ABL
T294 1430-1433 gene:25 denotes ABL
T295 1448-1451 disease:C0023467 denotes AML
R1 T284 T285 associated_with Bsp-1,myeloid leukemias
R2 T284 T285 associated_with Bsp-1,myeloid leukemias
R3 T286 T287 associated_with Bsp-1,chronic phase CML
R4 T286 T287 associated_with Bsp-1,chronic phase CML
R5 T286 T288 associated_with Bsp-1,blast crisis
R6 T286 T288 associated_with Bsp-1,blast crisis
R7 T286 T289 associated_with Bsp-1,CML
R8 T286 T289 associated_with Bsp-1,CML
R9 T286 T290 associated_with Bsp-1,AML
R10 T286 T290 associated_with Bsp-1,AML
R11 T291 T292 associated_with ABL,CML
R12 T291 T292 associated_with ABL,CML
R13 T293 T292 associated_with ABL,CML
R14 T293 T292 associated_with ABL,CML
R15 T294 T295 associated_with ABL,AML
R16 T294 T295 associated_with ABL,AML

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 206-211 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 206-211 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood