PubMed:26449539 / 884-1148 JSONTXT

{"project":"Inflammaging","denotations":[{"id":"T10","span":{"begin":0,"end":264},"obj":"Sentence"},{"id":"T10","span":{"begin":0,"end":264},"obj":"Sentence"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-sentences","denotations":[{"id":"T10","span":{"begin":0,"end":264},"obj":"Sentence"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-entities","denotations":[{"id":"10872","span":{"begin":22,"end":27},"obj":"GeneOrGeneProduct"},{"id":"10873","span":{"begin":56,"end":61},"obj":"ChemicalEntity"},{"id":"10874","span":{"begin":74,"end":79},"obj":"GeneOrGeneProduct"},{"id":"10875","span":{"begin":81,"end":87},"obj":"GeneOrGeneProduct"},{"id":"10876","span":{"begin":89,"end":94},"obj":"GeneOrGeneProduct"},{"id":"10877","span":{"begin":96,"end":103},"obj":"GeneOrGeneProduct"},{"id":"10878","span":{"begin":129,"end":132},"obj":"GeneOrGeneProduct"},{"id":"10879","span":{"begin":134,"end":139},"obj":"GeneOrGeneProduct"},{"id":"10880","span":{"begin":141,"end":147},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A24","pred":"db_id","subj":"10872","obj":"NCBIGene:5465"},{"id":"A25","pred":"db_id","subj":"10873","obj":"MESH:D008055"},{"id":"A26","pred":"db_id","subj":"10874","obj":"NCBIGene:51703"},{"id":"A27","pred":"db_id","subj":"10875","obj":"NCBIGene:84803"},{"id":"A28","pred":"db_id","subj":"10876","obj":"NCBIGene:3992"},{"id":"A29","pred":"db_id","subj":"10877","obj":"NCBIGene:10999"},{"id":"A30","pred":"db_id","subj":"10878","obj":"NCBIGene:5447"},{"id":"A31","pred":"db_id","subj":"10879","obj":"NCBIGene:1244"},{"id":"A32","pred":"db_id","subj":"10880","obj":"NCBIGene:1577"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T25","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":74,"end":79},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":81,"end":87},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":89,"end":94},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":96,"end":103},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":134,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":141,"end":147},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":156,"end":164},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":165,"end":172},"obj":"GeneOrGeneProduct"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T36","span":{"begin":0,"end":4},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":11,"end":18},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":28,"end":38},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":74,"end":79},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":81,"end":87},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":89,"end":94},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":96,"end":103},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":134,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":141,"end":147},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":156,"end":164},"obj":"GeneOrGeneProduct"},{"id":"T47","span":{"begin":165,"end":172},"obj":"GeneOrGeneProduct"},{"id":"T48","span":{"begin":240,"end":246},"obj":"GeneOrGeneProduct"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T16","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":74,"end":79},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":81,"end":87},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":89,"end":94},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":96,"end":103},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":134,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":141,"end":147},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":156,"end":164},"obj":"GeneOrGeneProduct"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":89,"end":94},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0100101"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T2","span":{"begin":106,"end":116},"obj":"ChemicalEntity"}],"attributes":[{"id":"A2","pred":"ID:","subj":"T2","obj":"D015262"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T2","span":{"begin":106,"end":116},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":156,"end":164},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":141,"end":147},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":134,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":96,"end":103},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":89,"end":94},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":81,"end":87},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":74,"end":79},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A2","pred":"ID:","subj":"T2","obj":"D015262"}],"text":"Many genes induced by PPARα activation were involved in lipid metabolism (ACSL5, AGPAT9, FADS1, SLC27A4), xenobiotic metabolism (POR, ABCC2, CYP3A5) or the unfolded protein response, whereas most of the downregulated genes were involved in immune-related pathways."}