PubMed:26405108
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-57 | Sentence | denotes | Flagellin glycosylation in Paenibacillus alvei CCM 2051T. |
| TextSentencer_T2 | 58-160 | Sentence | denotes | Flagellin glycosylation impacts, in several documented cases, the functionality of bacterial flagella. |
| TextSentencer_T3 | 161-424 | Sentence | denotes | The basis of flagellin glycosylation has been studied for various Gram-negative bacteria, but less is known about flagellin glycans of Gram-positive bacteria including Paenibacillus alvei, a secondary invader of honeybee colonies diseased with European foulbrood. |
| TextSentencer_T4 | 425-665 | Sentence | denotes | Paenibacillus alvei CCM 2051(T) swarms vigorously on solidified culture medium, with swarming relying on functional flagella as evidenced by abolished biofilm formation of a non-motile P. alvei mutant defective in the flagellin protein Hag. |
| TextSentencer_T5 | 666-737 | Sentence | denotes | Here, the glycobiology of the polar P. alvei flagella was investigated. |
| TextSentencer_T6 | 738-961 | Sentence | denotes | Analysis on purified flagellin demonstrated that the 30-kDa Hag protein (PAV_2c01710) is modified with an O-linked trisaccharide comprised of one hexose and two N-acetyl-hexosamine residues, at three sites of glycosylation. |
| TextSentencer_T7 | 962-1166 | Sentence | denotes | Downstream of the hag gene on the bacterial chromosome, two open reading frames (PAV_2c01630, PAV_2c01640) encoding putative glycosyltransferases were shown to constitute a flagellin glycosylation island. |
| TextSentencer_T8 | 1167-1365 | Sentence | denotes | Mutants defective in these genes exhibited altered migration in sodium dodecyl sulfate polyacrylamide gel electrophoresis as well as loss of extracellular flagella production and bacterial motility. |
| TextSentencer_T9 | 1366-1684 | Sentence | denotes | This study reveals that flagellin glycosylation in P. alvei is pivotal to flagella formation and bacterial motility in vivo, and simultaneously identifies flagella glycosylation as a second protein O-glycosylation system in this bacterium, in addition to the well-investigated S-layer tyrosine O-glycosylation pathway. |
| T1 | 0-57 | Sentence | denotes | Flagellin glycosylation in Paenibacillus alvei CCM 2051T. |
| T2 | 58-160 | Sentence | denotes | Flagellin glycosylation impacts, in several documented cases, the functionality of bacterial flagella. |
| T3 | 161-424 | Sentence | denotes | The basis of flagellin glycosylation has been studied for various Gram-negative bacteria, but less is known about flagellin glycans of Gram-positive bacteria including Paenibacillus alvei, a secondary invader of honeybee colonies diseased with European foulbrood. |
| T4 | 425-737 | Sentence | denotes | Paenibacillus alvei CCM 2051(T) swarms vigorously on solidified culture medium, with swarming relying on functional flagella as evidenced by abolished biofilm formation of a non-motile P. alvei mutant defective in the flagellin protein Hag. Here, the glycobiology of the polar P. alvei flagella was investigated. |
| T5 | 738-961 | Sentence | denotes | Analysis on purified flagellin demonstrated that the 30-kDa Hag protein (PAV_2c01710) is modified with an O-linked trisaccharide comprised of one hexose and two N-acetyl-hexosamine residues, at three sites of glycosylation. |
| T6 | 962-1166 | Sentence | denotes | Downstream of the hag gene on the bacterial chromosome, two open reading frames (PAV_2c01630, PAV_2c01640) encoding putative glycosyltransferases were shown to constitute a flagellin glycosylation island. |
| T7 | 1167-1365 | Sentence | denotes | Mutants defective in these genes exhibited altered migration in sodium dodecyl sulfate polyacrylamide gel electrophoresis as well as loss of extracellular flagella production and bacterial motility. |
| T8 | 1366-1684 | Sentence | denotes | This study reveals that flagellin glycosylation in P. alvei is pivotal to flagella formation and bacterial motility in vivo, and simultaneously identifies flagella glycosylation as a second protein O-glycosylation system in this bacterium, in addition to the well-investigated S-layer tyrosine O-glycosylation pathway. |
| T1 | 0-57 | Sentence | denotes | Flagellin glycosylation in Paenibacillus alvei CCM 2051T. |
| T2 | 58-160 | Sentence | denotes | Flagellin glycosylation impacts, in several documented cases, the functionality of bacterial flagella. |
| T3 | 161-424 | Sentence | denotes | The basis of flagellin glycosylation has been studied for various Gram-negative bacteria, but less is known about flagellin glycans of Gram-positive bacteria including Paenibacillus alvei, a secondary invader of honeybee colonies diseased with European foulbrood. |
| T4 | 425-665 | Sentence | denotes | Paenibacillus alvei CCM 2051(T) swarms vigorously on solidified culture medium, with swarming relying on functional flagella as evidenced by abolished biofilm formation of a non-motile P. alvei mutant defective in the flagellin protein Hag. |
| T5 | 666-737 | Sentence | denotes | Here, the glycobiology of the polar P. alvei flagella was investigated. |
| T6 | 738-961 | Sentence | denotes | Analysis on purified flagellin demonstrated that the 30-kDa Hag protein (PAV_2c01710) is modified with an O-linked trisaccharide comprised of one hexose and two N-acetyl-hexosamine residues, at three sites of glycosylation. |
| T7 | 962-1166 | Sentence | denotes | Downstream of the hag gene on the bacterial chromosome, two open reading frames (PAV_2c01630, PAV_2c01640) encoding putative glycosyltransferases were shown to constitute a flagellin glycosylation island. |
| T8 | 1167-1365 | Sentence | denotes | Mutants defective in these genes exhibited altered migration in sodium dodecyl sulfate polyacrylamide gel electrophoresis as well as loss of extracellular flagella production and bacterial motility. |
| T9 | 1366-1684 | Sentence | denotes | This study reveals that flagellin glycosylation in P. alvei is pivotal to flagella formation and bacterial motility in vivo, and simultaneously identifies flagella glycosylation as a second protein O-glycosylation system in this bacterium, in addition to the well-investigated S-layer tyrosine O-glycosylation pathway. |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 653-660 | FMAID:67257 | denotes | protein |
| _T2 | 653-660 | FMAID:165447 | denotes | protein |
| _T3 | 798-809 | FMAID:166112 | denotes | Hag protein |
| _T4 | 802-809 | FMAID:165447 | denotes | protein |
| _T5 | 802-809 | FMAID:67257 | denotes | protein |
| _T6 | 984-988 | FMAID:198663 | denotes | gene |
| _T7 | 1006-1016 | FMAID:165175 | denotes | chromosome |
| _T8 | 1006-1016 | FMAID:197979 | denotes | chromosome |
| _T9 | 1006-1016 | FMAID:84055 | denotes | chromosome |
| _T10 | 1006-1016 | FMAID:67093 | denotes | chromosome |
| _T11 | 1006-1016 | FMAID:226764 | denotes | chromosome |
| _T12 | 1006-1016 | FMAID:84056 | denotes | chromosome |
| _T13 | 1006-1016 | FMAID:197978 | denotes | chromosome |
| _T14 | 1194-1199 | FMAID:198663 | denotes | genes |
| _T15 | 1556-1563 | FMAID:67257 | denotes | protein |
| _T16 | 1556-1563 | FMAID:165447 | denotes | protein |
| _T17 | 1580-1589 | FMAID:185472 | denotes | system in |
| _T18 | 1580-1589 | FMAID:66644 | denotes | system in |
| _T19 | 1630-1650 | FMAID:183853 | denotes | investigated S-layer |
| _T20 | 1630-1650 | FMAID:76699 | denotes | investigated S-layer |
| _T21 | 1651-1659 | FMAID:82768 | denotes | tyrosine |
| _T22 | 1651-1659 | FMAID:196757 | denotes | tyrosine |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 27-40 | http://purl.bioontology.org/ontology/NCBITAXON/44251 | denotes | Paenibacillus |
| T2 | 27-40 | http://purl.bioontology.org/ontology/NCBITAXON/1338368 | denotes | Paenibacillus |
| T3 | 27-40 | http://purl.bioontology.org/ontology/NCBITAXON/44249 | denotes | Paenibacillus |
| T4 | 27-40 | http://purl.bioontology.org/ontology/NCBITAXON/1401 | denotes | Paenibacillus |
| T5 | 27-46 | http://purl.bioontology.org/ontology/NCBITAXON/44250 | denotes | Paenibacillus alvei |
| T6 | 227-249 | http://purl.bioontology.org/ontology/NCBITAXON/130805 | denotes | Gram-negative bacteria |
| T7 | 227-249 | http://purl.bioontology.org/ontology/NCBITAXON/130804 | denotes | Gram-negative bacteria |
| T8 | 241-249 | http://purl.bioontology.org/ontology/NCBITAXON/629395 | denotes | bacteria |
| T9 | 241-249 | http://purl.bioontology.org/ontology/NCBITAXON/2 | denotes | bacteria |
| T10 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/202530 | denotes | Gram-positive bacteria |
| T11 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/226202 | denotes | Gram-positive bacteria |
| T12 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/226203 | denotes | Gram-positive bacteria |
| T13 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/393789 | denotes | Gram-positive bacteria |
| T14 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/393790 | denotes | Gram-positive bacteria |
| T15 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/393791 | denotes | Gram-positive bacteria |
| T16 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/202527 | denotes | Gram-positive bacteria |
| T17 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/226199 | denotes | Gram-positive bacteria |
| T18 | 296-318 | http://purl.bioontology.org/ontology/NCBITAXON/202528 | denotes | Gram-positive bacteria |
| T19 | 310-318 | http://purl.bioontology.org/ontology/NCBITAXON/629395 | denotes | bacteria |
| T20 | 310-318 | http://purl.bioontology.org/ontology/NCBITAXON/2 | denotes | bacteria |
| T21 | 329-342 | http://purl.bioontology.org/ontology/NCBITAXON/1338368 | denotes | Paenibacillus |
| T22 | 329-342 | http://purl.bioontology.org/ontology/NCBITAXON/44249 | denotes | Paenibacillus |
| T23 | 329-342 | http://purl.bioontology.org/ontology/NCBITAXON/1401 | denotes | Paenibacillus |
| T24 | 329-342 | http://purl.bioontology.org/ontology/NCBITAXON/44251 | denotes | Paenibacillus |
| T25 | 329-348 | http://purl.bioontology.org/ontology/NCBITAXON/44250 | denotes | Paenibacillus alvei |
| T26 | 425-438 | http://purl.bioontology.org/ontology/NCBITAXON/44251 | denotes | Paenibacillus |
| T27 | 425-438 | http://purl.bioontology.org/ontology/NCBITAXON/1401 | denotes | Paenibacillus |
| T28 | 425-438 | http://purl.bioontology.org/ontology/NCBITAXON/44249 | denotes | Paenibacillus |
| T29 | 425-438 | http://purl.bioontology.org/ontology/NCBITAXON/1338368 | denotes | Paenibacillus |
| T30 | 425-444 | http://purl.bioontology.org/ontology/NCBITAXON/44250 | denotes | Paenibacillus alvei |
| T31 | 599-602 | http://purl.bioontology.org/ontology/NCBITAXON/604139 | denotes | non |
| T32 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/1368069 | denotes | bacterium |
| T33 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/1144558 | denotes | bacterium |
| T34 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/336404 | denotes | bacterium |
| T35 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/336403 | denotes | bacterium |
| T36 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/138290 | denotes | bacterium |
| T37 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/336400 | denotes | bacterium |
| T38 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538117 | denotes | bacterium |
| T39 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538113 | denotes | bacterium |
| T40 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/400048 | denotes | bacterium |
| T41 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538108 | denotes | bacterium |
| T42 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538107 | denotes | bacterium |
| T43 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/336405 | denotes | bacterium |
| T44 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538104 | denotes | bacterium |
| T45 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538101 | denotes | bacterium |
| T46 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/674166 | denotes | bacterium |
| T47 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538099 | denotes | bacterium |
| T48 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538097 | denotes | bacterium |
| T49 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538091 | denotes | bacterium |
| T50 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538085 | denotes | bacterium |
| T51 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538084 | denotes | bacterium |
| T52 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538076 | denotes | bacterium |
| T53 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538075 | denotes | bacterium |
| T54 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/538072 | denotes | bacterium |
| T55 | 1595-1604 | http://purl.bioontology.org/ontology/NCBITAXON/1730 | denotes | bacterium |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 10-23 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T2 | 68-81 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T3 | 184-197 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T4 | 947-960 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T5 | 1145-1158 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T6 | 1400-1413 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T7 | 1530-1543 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T8 | 1566-1579 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T9 | 1662-1675 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T10 | 584-593 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T11 | 1449-1458 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T12 | 1246-1253 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T13 | 1556-1579 | http://purl.obolibrary.org/obo/GO_0006493 | denotes | protein O-glycosylation |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1006-1016 | http://purl.obolibrary.org/obo/GO_0005694 | denotes | chromosome |
| T2 | 1308-1321 | http://purl.obolibrary.org/obo/GO_0005576 | denotes | extracellular |
| T3 | 1643-1650 | http://purl.obolibrary.org/obo/GO_0030115 | denotes | S-layer |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 102-112 | http://edamontology.org/topic_3068 | denotes | documented |
| T2 | 207-214 | http://edamontology.org/topic_3678 | denotes | studied |
| T3 | 391-399 | http://edamontology.org/topic_0634 | denotes | diseased |
| T4 | 653-660 | http://edamontology.org/topic_0078 | denotes | protein |
| T5 | 802-809 | http://edamontology.org/topic_0078 | denotes | protein |
| T6 | 1006-1016 | http://edamontology.org/topic_0624 | denotes | chromosome |
| T7 | 1006-1016 | http://edamontology.org/topic_0654 | denotes | chromosome |
| T8 | 1371-1376 | http://edamontology.org/topic_3678 | denotes | study |
| T9 | 1556-1563 | http://edamontology.org/topic_0078 | denotes | protein |
| T10 | 1676-1683 | http://edamontology.org/topic_0602 | denotes | pathway |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 102-112 | http://edamontology.org/data_2048 | denotes | documented |
| T2 | 124-137 | http://edamontology.org/operation_0004 | denotes | functionality |
| T3 | 553-562 | http://edamontology.org/data_2042 | denotes | evidenced |
| T4 | 576-593 | http://edamontology.org/format_3746 | denotes | biofilm formation |
| T5 | 584-593 | http://edamontology.org/operation_0335 | denotes | formation |
| T6 | 584-593 | http://edamontology.org/format_1915 | denotes | formation |
| T7 | 653-660 | http://edamontology.org/format_1208 | denotes | protein |
| T8 | 653-660 | http://edamontology.org/data_1467 | denotes | protein |
| T9 | 738-746 | http://edamontology.org/operation_2945 | denotes | Analysis |
| T10 | 769-781 | http://edamontology.org/operation_2246 | denotes | demonstrated |
| T11 | 802-809 | http://edamontology.org/data_1467 | denotes | protein |
| T12 | 802-809 | http://edamontology.org/format_1208 | denotes | protein |
| T13 | 919-927 | http://edamontology.org/data_1756 | denotes | residues |
| T14 | 1449-1458 | http://edamontology.org/format_1915 | denotes | formation |
| T15 | 1449-1458 | http://edamontology.org/operation_0335 | denotes | formation |
| T16 | 1510-1520 | http://edamontology.org/data_0842 | denotes | identifies |
| T17 | 1510-1520 | http://edamontology.org/data_2611 | denotes | identifies |
| T18 | 1556-1563 | http://edamontology.org/format_1208 | denotes | protein |
| T19 | 1556-1563 | http://edamontology.org/data_1467 | denotes | protein |
| T20 | 1676-1683 | http://edamontology.org/data_2600 | denotes | pathway |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1595-1604 | http://purl.obolibrary.org/obo/MAT_0000191 | denotes | bacterium |
GlyTouCan-IUPAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| GlycanIUPAC_T1 | 599-602 | "http://rdf.glycoinfo.org/glycan/G02780QX" | denotes | non |
| GlycanIUPAC_T2 | 599-602 | "http://rdf.glycoinfo.org/glycan/G18425DX" | denotes | non |
| GlycanIUPAC_T3 | 599-602 | "http://rdf.glycoinfo.org/glycan/G18630JE" | denotes | non |
| GlycanIUPAC_T4 | 599-602 | "http://rdf.glycoinfo.org/glycan/G01004IT" | denotes | non |
| GlycanIUPAC_T5 | 599-602 | "http://rdf.glycoinfo.org/glycan/G87301QZ" | denotes | non |
| GlycanIUPAC_T6 | 599-602 | "http://rdf.glycoinfo.org/glycan/G39790GW" | denotes | non |
| GlycanIUPAC_T7 | 599-602 | "http://rdf.glycoinfo.org/glycan/G42928BB" | denotes | non |
| GlycanIUPAC_T8 | 599-602 | "http://rdf.glycoinfo.org/glycan/G51134HC" | denotes | non |
| GlycanIUPAC_T9 | 599-602 | "http://rdf.glycoinfo.org/glycan/G68183GR" | denotes | non |
| GlycanIUPAC_T10 | 599-602 | "http://rdf.glycoinfo.org/glycan/G46883FA" | denotes | non |
| GlycanIUPAC_T11 | 599-602 | "http://rdf.glycoinfo.org/glycan/G54702VY" | denotes | non |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 47-50 | Disease | denotes | CCM | http://purl.obolibrary.org/obo/MONDO_0007291|http://purl.obolibrary.org/obo/MONDO_0020724 |
| T3 | 445-448 | Disease | denotes | CCM | http://purl.obolibrary.org/obo/MONDO_0007291|http://purl.obolibrary.org/obo/MONDO_0020724 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 27-46 | OrganismTaxon | denotes | Paenibacillus alvei | 44250 |
| T2 | 241-249 | OrganismTaxon | denotes | bacteria | 2|629395 |
| T4 | 310-318 | OrganismTaxon | denotes | bacteria | 2|629395 |
| T6 | 329-348 | OrganismTaxon | denotes | Paenibacillus alvei | 44250 |
| T7 | 373-381 | OrganismTaxon | denotes | honeybee | 7460 |
| T8 | 425-444 | OrganismTaxon | denotes | Paenibacillus alvei | 44250 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1006-1016 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T2 | 1308-1321 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T3 | 1645-1650 | Body_part | denotes | layer | http://purl.obolibrary.org/obo/UBERON_0000119|http://purl.obolibrary.org/obo/UBERON_0022303 |