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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-59 Sentence denotes Vitamin D, Inflammation, and Colorectal Cancer Progression:
T2 60-142 Sentence denotes A Review of Mechanistic Studies and Future Directions for Epidemiological Studies.
T3 143-222 Sentence denotes Survival from colorectal cancer is positively associated with vitamin D status.
T4 223-283 Sentence denotes However, whether this association is causal remains unclear.
T5 284-457 Sentence denotes Inflammatory processes may link vitamin D to colorectal cancer survival, and therefore investigating inflammatory markers as potential mediators may be a valuable next step.
T6 458-605 Sentence denotes This review starts with an overview of inflammatory processes suggested to be involved in colorectal cancer progression and regulated by vitamin D.
T7 606-752 Sentence denotes Next, we provide recommendations on how to study inflammatory markers in future epidemiologic studies on vitamin D and colorectal cancer survival.
T8 753-1023 Sentence denotes Mechanistic studies have shown that calcitriol-active form of vitamin D-influences inflammatory processes involved in cancer progression, including the enzyme cyclooxygenase 2, the NF-κB pathway, and the expression of the cytokines TNFα, IL1β, IL6, IL8, IL17, and TGFβ1.
T9 1024-1224 Sentence denotes Based on this and taking into account methodologic issues, we recommend to include analysis of specific soluble peptides and proteins, such as cytokines, in future epidemiologic studies on this issue.
T10 1225-1382 Sentence denotes Vitamin D and the markers should preferably be measured at multiple time points during disease progression or recovery and analyzed using mediation analysis.
T11 1383-1549 Sentence denotes Including these markers in epidemiologic studies may help answer whether inflammation mediates a causal relationship between vitamin D and colorectal cancer survival.
T12 1550-1611 Sentence denotes Cancer Epidemiol Biomarkers Prev; 24(12); 1820-8. ©2015 AACR.
T1 0-59 Sentence denotes Vitamin D, Inflammation, and Colorectal Cancer Progression:
T2 60-142 Sentence denotes A Review of Mechanistic Studies and Future Directions for Epidemiological Studies.
T3 143-222 Sentence denotes Survival from colorectal cancer is positively associated with vitamin D status.
T4 223-283 Sentence denotes However, whether this association is causal remains unclear.
T5 284-457 Sentence denotes Inflammatory processes may link vitamin D to colorectal cancer survival, and therefore investigating inflammatory markers as potential mediators may be a valuable next step.
T6 458-605 Sentence denotes This review starts with an overview of inflammatory processes suggested to be involved in colorectal cancer progression and regulated by vitamin D.
T7 606-752 Sentence denotes Next, we provide recommendations on how to study inflammatory markers in future epidemiologic studies on vitamin D and colorectal cancer survival.
T8 753-1023 Sentence denotes Mechanistic studies have shown that calcitriol-active form of vitamin D-influences inflammatory processes involved in cancer progression, including the enzyme cyclooxygenase 2, the NF-κB pathway, and the expression of the cytokines TNFα, IL1β, IL6, IL8, IL17, and TGFβ1.
T9 1024-1224 Sentence denotes Based on this and taking into account methodologic issues, we recommend to include analysis of specific soluble peptides and proteins, such as cytokines, in future epidemiologic studies on this issue.
T10 1225-1382 Sentence denotes Vitamin D and the markers should preferably be measured at multiple time points during disease progression or recovery and analyzed using mediation analysis.
T11 1383-1549 Sentence denotes Including these markers in epidemiologic studies may help answer whether inflammation mediates a causal relationship between vitamin D and colorectal cancer survival.
T12 1550-1611 Sentence denotes Cancer Epidemiol Biomarkers Prev; 24(12); 1820-8. ©2015 AACR.