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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-54 Sentence denotes [Civilian blast injuries: an underestimated problem? :
T2 55-119 Sentence denotes Results of a retrospective analysis of the TraumaRegister DGU®].
T3 120-177 Sentence denotes Zivile Explosionstraumata - ein unterschätztes Problem? :
T4 178-246 Sentence denotes Ergebnisse einer retrospektiven Analyse aus dem TraumaRegister DGU®.
T5 247-258 Sentence denotes BACKGROUND:
T6 259-343 Sentence denotes Blast injuries are a rare cause of potentially life-threatening injuries in Germany.
T7 344-516 Sentence denotes During the past 30 years such injuries were seldom the cause of mass casualties, therefore, knowledge and skills in dealing with this type of injury are not very extensive.
T8 517-538 Sentence denotes MATERIAL AND METHODS:
T9 539-735 Sentence denotes A retrospective identification of all patients in the TraumaRegister DGU® of the German Trauma Society (TR-DGU) who sustained blast injuries between January 1993 and November 2012 was carried out.
T10 736-844 Sentence denotes The study involved a descriptive characterization of the collective as well as three additional collectives.
T11 845-1043 Sentence denotes The arithmetic mean, standard deviation and 95 % confidence interval of the arithmetic mean for different demographic parameters and figures for prehospital and in-hospital settings were calculated.
T12 1044-1213 Sentence denotes A computation of prognostic scores, such as the Revised Injury Severity Classification (RISC) and the updated version RISC II (TR-DGU-Project-ID 2012-035) was performed.
T13 1214-1222 Sentence denotes RESULTS:
T14 1223-1316 Sentence denotes A total of 137 patients with blast injuries could be identified in the dataset of the TR-DGU.
T15 1317-1447 Sentence denotes Of the patients 90 % were male and 43 % were transported by the helicopter emergency service (HEMS) to the various trauma centres.
T16 1448-1569 Sentence denotes The severely injured collective with a mean injury severity scale (ISS) of 18.0 (ISS ≥ 16 = 52 %) had stable vital signs.
T17 1570-1771 Sentence denotes In none of the cases was it necessary to perform on-site emergency surgery but a very high proportion of patients (59 %) had to be surgically treated before admittance to the intensive care unit (ICU).
T18 1772-1906 Sentence denotes Of the patients 27 % had severe soft tissue injuries with an Abbreviated Injury Scale (AIS) ≥ 3 and 90 % of these injuries were burns.
T19 1907-2100 Sentence denotes The 24 h in-hospital fatality was very low (3 %) but the stay in the ICU tended to be longer than for other types of injury (mean 5.5 ventilation days and 10.7 days in the intensive care unit).
T20 2101-2199 Sentence denotes Organ failure occurred in 36 % of the cases, multiorgan failure in 29 % and septic events in 14 %.
T21 2200-2280 Sentence denotes Of the patients 16 % were transferred to another hospital during the first 48 h.
T22 2281-2602 Sentence denotes The RISC and the updated RISC II tended to underestimate the severity of injuries and mortality (10.2 % vs. 6.8 % and 10.7 % vs. 7.5 %, respectively) and the trauma associated severe hemorrhage (TASH) score underestimated the probability for transfusion of more than 10 units of packed red blood cells (5.0 % vs. 12.5 %).
T23 2603-2614 Sentence denotes CONCLUSION:
T24 2615-2715 Sentence denotes This article generates several hypotheses, which should be confirmed with additional investigations.
T25 2716-3052 Sentence denotes Until then it has to be concluded that patients who suffer from accidental blast injuries in the civilian setting (excluding military operations and terrorist attacks) show a combination of classical severe trauma with blunt and penetrating injuries and additionally a high proportion of severe burns (combined thermomechanical injury).
T26 3053-3177 Sentence denotes They stay longer in the ICU than other trauma patients and suffer more complications, such as sepsis and multiorgan failure.
T27 3178-3289 Sentence denotes Established scores, such as RISC, RISC II and TASH tend to underestimate the severity of the underlying trauma.
T1 0-54 Sentence denotes [Civilian blast injuries: an underestimated problem? :
T2 55-119 Sentence denotes Results of a retrospective analysis of the TraumaRegister DGU®].
T3 120-177 Sentence denotes Zivile Explosionstraumata - ein unterschätztes Problem? :
T4 178-246 Sentence denotes Ergebnisse einer retrospektiven Analyse aus dem TraumaRegister DGU®.
T5 247-258 Sentence denotes BACKGROUND:
T6 259-343 Sentence denotes Blast injuries are a rare cause of potentially life-threatening injuries in Germany.
T7 344-516 Sentence denotes During the past 30 years such injuries were seldom the cause of mass casualties, therefore, knowledge and skills in dealing with this type of injury are not very extensive.
T8 517-538 Sentence denotes MATERIAL AND METHODS:
T9 539-735 Sentence denotes A retrospective identification of all patients in the TraumaRegister DGU® of the German Trauma Society (TR-DGU) who sustained blast injuries between January 1993 and November 2012 was carried out.
T10 736-844 Sentence denotes The study involved a descriptive characterization of the collective as well as three additional collectives.
T11 845-1043 Sentence denotes The arithmetic mean, standard deviation and 95 % confidence interval of the arithmetic mean for different demographic parameters and figures for prehospital and in-hospital settings were calculated.
T12 1044-1213 Sentence denotes A computation of prognostic scores, such as the Revised Injury Severity Classification (RISC) and the updated version RISC II (TR-DGU-Project-ID 2012-035) was performed.
T13 1214-1222 Sentence denotes RESULTS:
T14 1223-1316 Sentence denotes A total of 137 patients with blast injuries could be identified in the dataset of the TR-DGU.
T15 1317-1447 Sentence denotes Of the patients 90 % were male and 43 % were transported by the helicopter emergency service (HEMS) to the various trauma centres.
T16 1448-1569 Sentence denotes The severely injured collective with a mean injury severity scale (ISS) of 18.0 (ISS ≥ 16 = 52 %) had stable vital signs.
T17 1570-1771 Sentence denotes In none of the cases was it necessary to perform on-site emergency surgery but a very high proportion of patients (59 %) had to be surgically treated before admittance to the intensive care unit (ICU).
T18 1772-1906 Sentence denotes Of the patients 27 % had severe soft tissue injuries with an Abbreviated Injury Scale (AIS) ≥ 3 and 90 % of these injuries were burns.
T19 1907-2100 Sentence denotes The 24 h in-hospital fatality was very low (3 %) but the stay in the ICU tended to be longer than for other types of injury (mean 5.5 ventilation days and 10.7 days in the intensive care unit).
T20 2101-2199 Sentence denotes Organ failure occurred in 36 % of the cases, multiorgan failure in 29 % and septic events in 14 %.
T21 2200-2280 Sentence denotes Of the patients 16 % were transferred to another hospital during the first 48 h.
T22 2281-2602 Sentence denotes The RISC and the updated RISC II tended to underestimate the severity of injuries and mortality (10.2 % vs. 6.8 % and 10.7 % vs. 7.5 %, respectively) and the trauma associated severe hemorrhage (TASH) score underestimated the probability for transfusion of more than 10 units of packed red blood cells (5.0 % vs. 12.5 %).
T23 2603-2614 Sentence denotes CONCLUSION:
T24 2615-2715 Sentence denotes This article generates several hypotheses, which should be confirmed with additional investigations.
T25 2716-3052 Sentence denotes Until then it has to be concluded that patients who suffer from accidental blast injuries in the civilian setting (excluding military operations and terrorist attacks) show a combination of classical severe trauma with blunt and penetrating injuries and additionally a high proportion of severe burns (combined thermomechanical injury).
T26 3053-3177 Sentence denotes They stay longer in the ICU than other trauma patients and suffer more complications, such as sepsis and multiorgan failure.
T27 3178-3289 Sentence denotes Established scores, such as RISC, RISC II and TASH tend to underestimate the severity of the underlying trauma.