PubMed:26215578 / 134-598 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/26215578","sourcedb":"PubMed","sourceid":"26215578","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/26215578","text":"The epidermal growth factor (EGF) family of ligands has been implicated in promoting breast cancer initiation, growth and progression. The contributions of EGF family ligands and their receptors to breast cancer are complex, and the specific mechanisms through which different ligands regulate breast tumor initiation and growth are not well-defined. These studies focus on the EGF family member epiregulin (EREG) as a mediator of early stage breast tumorigenesis.","tracks":[{"project":"c_corpus","denotations":[{"id":"T20","span":{"begin":4,"end":20},"obj":"UBERON:0000021"},{"id":"T23","span":{"begin":4,"end":27},"obj":"Q9GU69"},{"id":"T21","span":{"begin":4,"end":27},"obj":"D004815"},{"id":"T22","span":{"begin":4,"end":27},"obj":"D004815"},{"id":"T24","span":{"begin":4,"end":27},"obj":"GO:0005154"},{"id":"T30","span":{"begin":29,"end":32},"obj":"Q95ND4"},{"id":"T32","span":{"begin":29,"end":32},"obj":"PR:P01133"},{"id":"T33","span":{"begin":29,"end":32},"obj":"P01133"},{"id":"T34","span":{"begin":29,"end":32},"obj":"PR:P07522"},{"id":"T35","span":{"begin":29,"end":32},"obj":"PR:P01132"},{"id":"T36","span":{"begin":29,"end":32},"obj":"Q9BEA0"},{"id":"T37","span":{"begin":29,"end":32},"obj":"P01132"},{"id":"T38","span":{"begin":29,"end":32},"obj":"P07522"},{"id":"T40","span":{"begin":29,"end":32},"obj":"PR:000006928"},{"id":"T41","span":{"begin":29,"end":32},"obj":"P26224"},{"id":"T43","span":{"begin":29,"end":32},"obj":"Q00968"},{"id":"T31","span":{"begin":29,"end":32},"obj":"CHEBI:140739"},{"id":"T42","span":{"begin":29,"end":32},"obj":"D004815"},{"id":"T44","span":{"begin":29,"end":32},"obj":"D004815"},{"id":"T39","span":{"begin":29,"end":32},"obj":"GO:0005154"},{"id":"T45","span":{"begin":44,"end":51},"obj":"CHEBI:52214"},{"id":"T46","span":{"begin":85,"end":91},"obj":"UBERON:0000310"},{"id":"T47","span":{"begin":85,"end":98},"obj":"D001943"},{"id":"T48","span":{"begin":85,"end":98},"obj":"D001943"},{"id":"T49","span":{"begin":156,"end":159},"obj":"Q95ND4"},{"id":"T51","span":{"begin":156,"end":159},"obj":"PR:P01133"},{"id":"T52","span":{"begin":156,"end":159},"obj":"P01133"},{"id":"T53","span":{"begin":156,"end":159},"obj":"PR:P07522"},{"id":"T54","span":{"begin":156,"end":159},"obj":"PR:P01132"},{"id":"T55","span":{"begin":156,"end":159},"obj":"Q9BEA0"},{"id":"T56","span":{"begin":156,"end":159},"obj":"P01132"},{"id":"T57","span":{"begin":156,"end":159},"obj":"P07522"},{"id":"T59","span":{"begin":156,"end":159},"obj":"PR:000006928"},{"id":"T60","span":{"begin":156,"end":159},"obj":"P26224"},{"id":"T62","span":{"begin":156,"end":159},"obj":"Q00968"},{"id":"T50","span":{"begin":156,"end":159},"obj":"CHEBI:140739"},{"id":"T61","span":{"begin":156,"end":159},"obj":"D004815"},{"id":"T63","span":{"begin":156,"end":159},"obj":"D004815"},{"id":"T58","span":{"begin":156,"end":159},"obj":"GO:0005154"},{"id":"T64","span":{"begin":167,"end":174},"obj":"CHEBI:52214"},{"id":"T65","span":{"begin":198,"end":204},"obj":"UBERON:0000310"},{"id":"T66","span":{"begin":198,"end":211},"obj":"D001943"},{"id":"T67","span":{"begin":198,"end":211},"obj":"D001943"},{"id":"T68","span":{"begin":277,"end":284},"obj":"CHEBI:52214"},{"id":"T69","span":{"begin":294,"end":300},"obj":"UBERON:0000310"},{"id":"T70","span":{"begin":294,"end":306},"obj":"D001943"},{"id":"T71","span":{"begin":294,"end":306},"obj":"D001943"},{"id":"T74","span":{"begin":378,"end":381},"obj":"Q95ND4"},{"id":"T76","span":{"begin":378,"end":381},"obj":"PR:P01133"},{"id":"T77","span":{"begin":378,"end":381},"obj":"P01133"},{"id":"T78","span":{"begin":378,"end":381},"obj":"PR:P07522"},{"id":"T79","span":{"begin":378,"end":381},"obj":"PR:P01132"},{"id":"T80","span":{"begin":378,"end":381},"obj":"Q9BEA0"},{"id":"T81","span":{"begin":378,"end":381},"obj":"P01132"},{"id":"T82","span":{"begin":378,"end":381},"obj":"P07522"},{"id":"T84","span":{"begin":378,"end":381},"obj":"PR:000006928"},{"id":"T85","span":{"begin":378,"end":381},"obj":"P26224"},{"id":"T87","span":{"begin":378,"end":381},"obj":"Q00968"},{"id":"T75","span":{"begin":378,"end":381},"obj":"CHEBI:140739"},{"id":"T86","span":{"begin":378,"end":381},"obj":"D004815"},{"id":"T88","span":{"begin":378,"end":381},"obj":"D004815"},{"id":"T83","span":{"begin":378,"end":381},"obj":"GO:0005154"},{"id":"T89","span":{"begin":396,"end":406},"obj":"D066260"},{"id":"T90","span":{"begin":396,"end":406},"obj":"D066260"},{"id":"T91","span":{"begin":408,"end":412},"obj":"PR:000007171"},{"id":"T92","span":{"begin":408,"end":412},"obj":"PR:O14944"},{"id":"T93","span":{"begin":408,"end":412},"obj":"PR:Q61521"},{"id":"T94","span":{"begin":408,"end":412},"obj":"PR:Q9Z0L5"},{"id":"T95","span":{"begin":443,"end":449},"obj":"UBERON:0000310"},{"id":"T96","span":{"begin":450,"end":463},"obj":"D063646"},{"id":"T97","span":{"begin":450,"end":463},"obj":"D063646"}],"attributes":[{"subj":"T20","pred":"source","obj":"c_corpus"},{"subj":"T23","pred":"source","obj":"c_corpus"},{"subj":"T21","pred":"source","obj":"c_corpus"},{"subj":"T22","pred":"source","obj":"c_corpus"},{"subj":"T24","pred":"source","obj":"c_corpus"},{"subj":"T30","pred":"source","obj":"c_corpus"},{"subj":"T32","pred":"source","obj":"c_corpus"},{"subj":"T33","pred":"source","obj":"c_corpus"},{"subj":"T34","pred":"source","obj":"c_corpus"},{"subj":"T35","pred":"source","obj":"c_corpus"},{"subj":"T36","pred":"source","obj":"c_corpus"},{"subj":"T37","pred":"source","obj":"c_corpus"},{"subj":"T38","pred":"source","obj":"c_corpus"},{"subj":"T40","pred":"source","obj":"c_corpus"},{"subj":"T41","pred":"source","obj":"c_corpus"},{"subj":"T43","pred":"source","obj":"c_corpus"},{"subj":"T31","pred":"source","obj":"c_corpus"},{"subj":"T42","pred":"source","obj":"c_corpus"},{"subj":"T44","pred":"source","obj":"c_corpus"},{"subj":"T39","pred":"source","obj":"c_corpus"},{"subj":"T45","pred":"source","obj":"c_corpus"},{"subj":"T46","pred":"source","obj":"c_corpus"},{"subj":"T47","pred":"source","obj":"c_corpus"},{"subj":"T48","pred":"source","obj":"c_corpus"},{"subj":"T49","pred":"source","obj":"c_corpus"},{"subj":"T51","pred":"source","obj":"c_corpus"},{"subj":"T52","pred":"source","obj":"c_corpus"},{"subj":"T53","pred":"source","obj":"c_corpus"},{"subj":"T54","pred":"source","obj":"c_corpus"},{"subj":"T55","pred":"source","obj":"c_corpus"},{"subj":"T56","pred":"source","obj":"c_corpus"},{"subj":"T57","pred":"source","obj":"c_corpus"},{"subj":"T59","pred":"source","obj":"c_corpus"},{"subj":"T60","pred":"source","obj":"c_corpus"},{"subj":"T62","pred":"source","obj":"c_corpus"},{"subj":"T50","pred":"source","obj":"c_corpus"},{"subj":"T61","pred":"source","obj":"c_corpus"},{"subj":"T63","pred":"source","obj":"c_corpus"},{"subj":"T58","pred":"source","obj":"c_corpus"},{"subj":"T64","pred":"source","obj":"c_corpus"},{"subj":"T65","pred":"source","obj":"c_corpus"},{"subj":"T66","pred":"source","obj":"c_corpus"},{"subj":"T67","pred":"source","obj":"c_corpus"},{"subj":"T68","pred":"source","obj":"c_corpus"},{"subj":"T69","pred":"source","obj":"c_corpus"},{"subj":"T70","pred":"source","obj":"c_corpus"},{"subj":"T71","pred":"source","obj":"c_corpus"},{"subj":"T74","pred":"source","obj":"c_corpus"},{"subj":"T76","pred":"source","obj":"c_corpus"},{"subj":"T77","pred":"source","obj":"c_corpus"},{"subj":"T78","pred":"source","obj":"c_corpus"},{"subj":"T79","pred":"source","obj":"c_corpus"},{"subj":"T80","pred":"source","obj":"c_corpus"},{"subj":"T81","pred":"source","obj":"c_corpus"},{"subj":"T82","pred":"source","obj":"c_corpus"},{"subj":"T84","pred":"source","obj":"c_corpus"},{"subj":"T85","pred":"source","obj":"c_corpus"},{"subj":"T87","pred":"source","obj":"c_corpus"},{"subj":"T75","pred":"source","obj":"c_corpus"},{"subj":"T86","pred":"source","obj":"c_corpus"},{"subj":"T88","pred":"source","obj":"c_corpus"},{"subj":"T83","pred":"source","obj":"c_corpus"},{"subj":"T89","pred":"source","obj":"c_corpus"},{"subj":"T90","pred":"source","obj":"c_corpus"},{"subj":"T91","pred":"source","obj":"c_corpus"},{"subj":"T92","pred":"source","obj":"c_corpus"},{"subj":"T93","pred":"source","obj":"c_corpus"},{"subj":"T94","pred":"source","obj":"c_corpus"},{"subj":"T95","pred":"source","obj":"c_corpus"},{"subj":"T96","pred":"source","obj":"c_corpus"},{"subj":"T97","pred":"source","obj":"c_corpus"}]},{"project":"UseCases_ArguminSci_Discourse","denotations":[{"id":"T2","span":{"begin":0,"end":134},"obj":"DRI_Outcome"},{"id":"T3","span":{"begin":135,"end":350},"obj":"DRI_Approach"},{"id":"T4","span":{"begin":351,"end":464},"obj":"DRI_Background"}],"attributes":[{"subj":"T2","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T3","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T4","pred":"source","obj":"UseCases_ArguminSci_Discourse"}]},{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":0,"end":464},"obj":"BACKGROUND"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_Structured_Abstracts"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"26215578-0#0#10#gene2069","span":{"begin":29,"end":172},"obj":"gene2069"},{"id":"26215578-0#33#46#diseaseC0596263","span":{"begin":438,"end":463},"obj":"diseaseC0596263"},{"id":"26215578-2#21#24#gene1950","span":{"begin":156,"end":159},"obj":"gene1950"},{"id":"26215578-2#21#24#gene1950","span":{"begin":156,"end":159},"obj":"gene1950"},{"id":"26215578-2#63#76#diseaseC0006142","span":{"begin":198,"end":211},"obj":"diseaseC0006142"},{"id":"26215578-2#63#76#diseaseC0678222","span":{"begin":198,"end":211},"obj":"diseaseC0678222"},{"id":"26215578-2#159#171#diseaseC1458155","span":{"begin":294,"end":306},"obj":"diseaseC1458155"},{"id":"26215578-3#27#30#gene1950","span":{"begin":378,"end":381},"obj":"gene1950"},{"id":"26215578-3#99#112#diseaseC0596263","span":{"begin":450,"end":463},"obj":"diseaseC0596263"}],"relations":[{"id":"0#10#gene206933#46#diseaseC0596263","pred":"associated_with","subj":"26215578-0#0#10#gene2069","obj":"26215578-0#33#46#diseaseC0596263"},{"id":"21#24#gene195063#76#diseaseC0006142","pred":"associated_with","subj":"26215578-2#21#24#gene1950","obj":"26215578-2#63#76#diseaseC0006142"},{"id":"21#24#gene195063#76#diseaseC0678222","pred":"associated_with","subj":"26215578-2#21#24#gene1950","obj":"26215578-2#63#76#diseaseC0678222"},{"id":"21#24#gene1950159#171#diseaseC1458155","pred":"associated_with","subj":"26215578-2#21#24#gene1950","obj":"26215578-2#159#171#diseaseC1458155"},{"id":"21#24#gene195063#76#diseaseC0006142","pred":"associated_with","subj":"26215578-2#21#24#gene1950","obj":"26215578-2#63#76#diseaseC0006142"},{"id":"21#24#gene195063#76#diseaseC0678222","pred":"associated_with","subj":"26215578-2#21#24#gene1950","obj":"26215578-2#63#76#diseaseC0678222"},{"id":"21#24#gene1950159#171#diseaseC1458155","pred":"associated_with","subj":"26215578-2#21#24#gene1950","obj":"26215578-2#159#171#diseaseC1458155"},{"id":"27#30#gene195099#112#diseaseC0596263","pred":"associated_with","subj":"26215578-3#27#30#gene1950","obj":"26215578-3#99#112#diseaseC0596263"}],"attributes":[{"subj":"26215578-0#0#10#gene2069","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-0#33#46#diseaseC0596263","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-2#21#24#gene1950","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-2#21#24#gene1950","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-2#63#76#diseaseC0006142","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-2#63#76#diseaseC0678222","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-2#159#171#diseaseC1458155","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-3#27#30#gene1950","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26215578-3#99#112#diseaseC0596263","pred":"source","obj":"DisGeNET5_gene_disease"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"c_corpus","color":"#ec93b6","default":true},{"id":"UseCases_ArguminSci_Discourse","color":"#93d0ec"},{"id":"PubMed_Structured_Abstracts","color":"#eaec93"},{"id":"DisGeNET5_gene_disease","color":"#d493ec"}]}]}}