PubMed:26169094
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/26169094","sourcedb":"PubMed","sourceid":"26169094","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/26169094","text":"The therapeutic effect of high-dose esomeprazole on stress ulcer bleeding in trauma patients.\nPURPOSE: To compare the therapeutic effects of different doses of intravenous esomeprazole on treating trauma patients with stress ulcer bleeding.\nMETHODS: A total of 102 trauma patients with stress ulcer bleeding were randomly divided into 2 groups: 52 patients were assigned to the high-dose group who received 80 mg intravenous esomeprazole, and then 8 mg/h continuous infusion for 3 days; 50 patients were assigned to the conventional dose group who received 40 mg intravenous esomeprazole sodium once every 12 h for 72 h.\nRESULTS: Compared with the conventional dose group, the total efficiency of the high-dose group and conventional dose group was 98.08% and 86.00%, respectively (p \u003c 0.05), the hemostatic time was 22.10 h ± 5.18 h and 28.27 h ± 5.96 h, respectively (p \u003c 0.05).\nCONCLUSION: Both doses of intravenous esomeprazole have good hemostatic effects on stress ulcer bleeding in trauma patients. The high-dose esomeprazole is better for hemostasis.","tracks":[{"project":"Zierdiyeerkenaili_800_3","denotations":[{"id":"T1","span":{"begin":36,"end":48},"obj":"CI"},{"id":"T2","span":{"begin":172,"end":184},"obj":"CI"},{"id":"T3","span":{"begin":425,"end":437},"obj":"CI"},{"id":"T4","span":{"begin":575,"end":587},"obj":"CI"},{"id":"T5","span":{"begin":919,"end":931},"obj":"CI"},{"id":"T6","span":{"begin":1020,"end":1032},"obj":"CI"},{"id":"T7","span":{"begin":197,"end":239},"obj":"DP"},{"id":"T8","span":{"begin":265,"end":307},"obj":"DP"},{"id":"T9","span":{"begin":52,"end":83},"obj":"DP"},{"id":"T10","span":{"begin":964,"end":995},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T2","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T3","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T4","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T5","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T6","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T7","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T8","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T9","pred":"source","obj":"Zierdiyeerkenaili_800_3"},{"subj":"T10","pred":"source","obj":"Zierdiyeerkenaili_800_3"}]},{"project":"yaoziqian_800_3","denotations":[{"id":"T1","span":{"begin":36,"end":48},"obj":"CI"},{"id":"T10","span":{"begin":1020,"end":1032},"obj":"CI"},{"id":"T11","span":{"begin":197,"end":239},"obj":"DP"},{"id":"T12","span":{"begin":265,"end":307},"obj":"DP"},{"id":"T3","span":{"begin":172,"end":184},"obj":"CI"},{"id":"T6","span":{"begin":425,"end":437},"obj":"CI"},{"id":"T7","span":{"begin":575,"end":587},"obj":"CI"},{"id":"T8","span":{"begin":919,"end":931},"obj":"CI"},{"id":"T15","span":{"begin":52,"end":83},"obj":"DP"},{"id":"T16","span":{"begin":964,"end":995},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T10","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T11","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T12","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T3","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T6","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T7","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T8","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T15","pred":"source","obj":"yaoziqian_800_3"},{"subj":"T16","pred":"source","obj":"yaoziqian_800_3"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Zierdiyeerkenaili_800_3","color":"#93dfec","default":true},{"id":"yaoziqian_800_3","color":"#ecdf93"}]}]}}