PubMed:26153105 / 624-944 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PubMed/sourceid/26153105","sourcedb":"PubMed","sourceid":"26153105","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/26153105","text":"Using glycosyltransferase-programmed stereosubstitution (GPS), we glycan engineered the cell surface of NSCs (\"GPS-NSCs\") with resultant enforced expression of the potent E-selectin ligand HCELL (hematopoietic cell E-/L-selectin ligand) and of an E-selectin-binding glycoform of neural cell adhesion molecule (\"NCAM-E\").","tracks":[{"project":"GlyCosmos6-UBERON","denotations":[{"id":"T9","span":{"begin":88,"end":92},"obj":"Body_part"},{"id":"T10","span":{"begin":93,"end":100},"obj":"Body_part"},{"id":"T11","span":{"begin":196,"end":214},"obj":"Body_part"},{"id":"T12","span":{"begin":279,"end":290},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_0002416"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CL_0000988"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CL_0002319"},{"subj":"T9","pred":"source","obj":"GlyCosmos6-UBERON"},{"subj":"T10","pred":"source","obj":"GlyCosmos6-UBERON"},{"subj":"T11","pred":"source","obj":"GlyCosmos6-UBERON"},{"subj":"T12","pred":"source","obj":"GlyCosmos6-UBERON"}]},{"project":"Inflammaging","denotations":[{"id":"T5","span":{"begin":0,"end":320},"obj":"Sentence"},{"id":"T5","span":{"begin":0,"end":320},"obj":"Sentence"}],"attributes":[{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"}]},{"project":"PubMed_ArguminSci","denotations":[{"id":"T4","span":{"begin":0,"end":5},"obj":"DRI_Approach"},{"id":"T5","span":{"begin":56,"end":246},"obj":"DRI_Approach"},{"id":"T6","span":{"begin":276,"end":320},"obj":"DRI_Approach"}],"attributes":[{"subj":"T4","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T5","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T6","pred":"source","obj":"PubMed_ArguminSci"}]},{"project":"sentences","denotations":[{"id":"TextSentencer_T5","span":{"begin":0,"end":320},"obj":"Sentence"},{"id":"T5","span":{"begin":0,"end":320},"obj":"Sentence"},{"id":"T5","span":{"begin":0,"end":320},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T5","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"}]},{"project":"mondo_disease","denotations":[{"id":"T4","span":{"begin":57,"end":60},"obj":"Disease"},{"id":"T5","span":{"begin":111,"end":114},"obj":"Disease"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0007686"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0007686"},{"subj":"T4","pred":"source","obj":"mondo_disease"},{"subj":"T5","pred":"source","obj":"mondo_disease"}]},{"project":"GlyCosmos6-CLO","denotations":[{"id":"T11","span":{"begin":88,"end":92},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T12","span":{"begin":196,"end":214},"obj":"http://purl.obolibrary.org/obo/CL_0000988"},{"id":"T13","span":{"begin":210,"end":214},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T14","span":{"begin":286,"end":290},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T11","pred":"source","obj":"GlyCosmos6-CLO"},{"subj":"T12","pred":"source","obj":"GlyCosmos6-CLO"},{"subj":"T13","pred":"source","obj":"GlyCosmos6-CLO"},{"subj":"T14","pred":"source","obj":"GlyCosmos6-CLO"}]},{"project":"GlycoBiology-FMA","denotations":[{"id":"_T42","span":{"begin":88,"end":100},"obj":"FMAID:212684"},{"id":"_T43","span":{"begin":88,"end":100},"obj":"FMAID:200942"},{"id":"_T44","span":{"begin":93,"end":100},"obj":"FMAID:50594"},{"id":"_T45","span":{"begin":93,"end":100},"obj":"FMAID:146300"},{"id":"_T46","span":{"begin":171,"end":181},"obj":"FMAID:167265"},{"id":"_T47","span":{"begin":171,"end":181},"obj":"FMAID:62933"},{"id":"_T48","span":{"begin":171,"end":181},"obj":"FMAID:62932"},{"id":"_T49","span":{"begin":171,"end":181},"obj":"FMAID:167268"},{"id":"_T50","span":{"begin":171,"end":181},"obj":"FMAID:62931"},{"id":"_T51","span":{"begin":171,"end":181},"obj":"FMAID:167267"},{"id":"_T52","span":{"begin":173,"end":181},"obj":"FMAID:165243"},{"id":"_T53","span":{"begin":173,"end":181},"obj":"FMAID:61795"},{"id":"_T54","span":{"begin":196,"end":214},"obj":"FMAID:83598"},{"id":"_T55","span":{"begin":196,"end":214},"obj":"FMAID:197894"},{"id":"_T56","span":{"begin":196,"end":214},"obj":"FMAID:197893"},{"id":"_T57","span":{"begin":196,"end":214},"obj":"FMAID:201460"},{"id":"_T58","span":{"begin":215,"end":228},"obj":"FMAID:62932"},{"id":"_T59","span":{"begin":215,"end":228},"obj":"FMAID:167267"},{"id":"_T60","span":{"begin":218,"end":228},"obj":"FMAID:62931"},{"id":"_T61","span":{"begin":218,"end":228},"obj":"FMAID:167265"},{"id":"_T62","span":{"begin":218,"end":228},"obj":"FMAID:167268"},{"id":"_T63","span":{"begin":218,"end":228},"obj":"FMAID:62933"},{"id":"_T64","span":{"begin":220,"end":228},"obj":"FMAID:165243"},{"id":"_T65","span":{"begin":220,"end":228},"obj":"FMAID:61795"},{"id":"_T66","span":{"begin":247,"end":257},"obj":"FMAID:62932"},{"id":"_T67","span":{"begin":247,"end":257},"obj":"FMAID:62931"},{"id":"_T68","span":{"begin":247,"end":257},"obj":"FMAID:167265"},{"id":"_T69","span":{"begin":247,"end":257},"obj":"FMAID:167267"},{"id":"_T70","span":{"begin":247,"end":257},"obj":"FMAID:167268"},{"id":"_T71","span":{"begin":247,"end":257},"obj":"FMAID:62933"},{"id":"_T72","span":{"begin":249,"end":257},"obj":"FMAID:61795"},{"id":"_T73","span":{"begin":249,"end":257},"obj":"FMAID:165243"},{"id":"_T74","span":{"begin":279,"end":308},"obj":"FMAID:165776"},{"id":"_T75","span":{"begin":279,"end":308},"obj":"FMAID:67856"},{"id":"_T76","span":{"begin":286,"end":308},"obj":"FMAID:67214"},{"id":"_T77","span":{"begin":286,"end":308},"obj":"FMAID:167237"},{"id":"_T78","span":{"begin":286,"end":308},"obj":"FMAID:165233"},{"id":"_T79","span":{"begin":286,"end":308},"obj":"FMAID:167238"},{"id":"_T80","span":{"begin":286,"end":308},"obj":"FMAID:62914"},{"id":"_T81","span":{"begin":286,"end":308},"obj":"FMAID:62915"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"attributes":[{"subj":"_T42","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T43","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T44","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T45","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T46","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T47","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T48","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T49","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T50","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T51","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T52","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T53","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T54","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T55","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T56","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T57","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T58","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T59","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T60","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T61","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T62","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T63","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T64","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T65","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T66","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T67","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T68","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T69","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T70","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T71","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T72","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T73","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T74","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T75","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T76","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T77","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T78","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T79","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T80","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T81","pred":"source","obj":"GlycoBiology-FMA"}]},{"project":"uniprot-human","denotations":[{"id":"T2","span":{"begin":171,"end":181},"obj":"http://www.uniprot.org/uniprot/P16581"},{"id":"T3","span":{"begin":247,"end":257},"obj":"http://www.uniprot.org/uniprot/P16581"},{"id":"T5","span":{"begin":171,"end":188},"obj":"http://www.uniprot.org/uniprot/Q92896"},{"id":"T6","span":{"begin":220,"end":248},"obj":"http://www.uniprot.org/uniprot/Q92896"},{"id":"T7","span":{"begin":218,"end":228},"obj":"http://www.uniprot.org/uniprot/P14151"},{"id":"T8","span":{"begin":218,"end":235},"obj":"http://www.uniprot.org/uniprot/Q8NCG5"},{"id":"T9","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/P16422"},{"id":"T10","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/P43121"},{"id":"T11","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/Q14CZ8"},{"id":"T12","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/Q8N126"},{"id":"T13","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/Q8NFZ8"},{"id":"T14","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/P50895"},{"id":"T15","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/Q8N3J6"},{"id":"T16","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/Q8N2F4"},{"id":"T17","span":{"begin":286,"end":308},"obj":"http://www.uniprot.org/uniprot/Q92823"},{"id":"T18","span":{"begin":311,"end":315},"obj":"http://www.uniprot.org/uniprot/Q59FL7"}],"attributes":[{"subj":"T2","pred":"source","obj":"uniprot-human"},{"subj":"T3","pred":"source","obj":"uniprot-human"},{"subj":"T5","pred":"source","obj":"uniprot-human"},{"subj":"T6","pred":"source","obj":"uniprot-human"},{"subj":"T7","pred":"source","obj":"uniprot-human"},{"subj":"T8","pred":"source","obj":"uniprot-human"},{"subj":"T9","pred":"source","obj":"uniprot-human"},{"subj":"T10","pred":"source","obj":"uniprot-human"},{"subj":"T11","pred":"source","obj":"uniprot-human"},{"subj":"T12","pred":"source","obj":"uniprot-human"},{"subj":"T13","pred":"source","obj":"uniprot-human"},{"subj":"T14","pred":"source","obj":"uniprot-human"},{"subj":"T15","pred":"source","obj":"uniprot-human"},{"subj":"T16","pred":"source","obj":"uniprot-human"},{"subj":"T17","pred":"source","obj":"uniprot-human"},{"subj":"T18","pred":"source","obj":"uniprot-human"}]},{"project":"uniprot-mouse","denotations":[{"id":"T2","span":{"begin":171,"end":181},"obj":"http://www.uniprot.org/uniprot/Q00690"},{"id":"T3","span":{"begin":247,"end":257},"obj":"http://www.uniprot.org/uniprot/Q00690"},{"id":"T4","span":{"begin":218,"end":228},"obj":"http://www.uniprot.org/uniprot/P18337"}],"attributes":[{"subj":"T2","pred":"source","obj":"uniprot-mouse"},{"subj":"T3","pred":"source","obj":"uniprot-mouse"},{"subj":"T4","pred":"source","obj":"uniprot-mouse"}]},{"project":"GO-BP","denotations":[{"id":"T3","span":{"begin":286,"end":299},"obj":"http://purl.obolibrary.org/obo/GO_0007155"},{"id":"T4","span":{"begin":286,"end":308},"obj":"http://purl.obolibrary.org/obo/GO_0060352"},{"id":"T5","span":{"begin":286,"end":308},"obj":"http://purl.obolibrary.org/obo/GO_0007155"}],"attributes":[{"subj":"T3","pred":"source","obj":"GO-BP"},{"subj":"T4","pred":"source","obj":"GO-BP"},{"subj":"T5","pred":"source","obj":"GO-BP"}]},{"project":"GO-MF","denotations":[{"id":"T2","span":{"begin":173,"end":181},"obj":"http://purl.obolibrary.org/obo/GO_0030246"},{"id":"T3","span":{"begin":220,"end":228},"obj":"http://purl.obolibrary.org/obo/GO_0030246"},{"id":"T4","span":{"begin":249,"end":257},"obj":"http://purl.obolibrary.org/obo/GO_0030246"},{"id":"T6","span":{"begin":182,"end":188},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T7","span":{"begin":229,"end":235},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T8","span":{"begin":258,"end":265},"obj":"http://purl.obolibrary.org/obo/GO_0070026"},{"id":"T9","span":{"begin":258,"end":265},"obj":"http://purl.obolibrary.org/obo/GO_0003680"},{"id":"T10","span":{"begin":258,"end":265},"obj":"http://purl.obolibrary.org/obo/GO_0017091"},{"id":"T11","span":{"begin":258,"end":265},"obj":"http://purl.obolibrary.org/obo/GO_0005488"}],"attributes":[{"subj":"T2","pred":"source","obj":"GO-MF"},{"subj":"T3","pred":"source","obj":"GO-MF"},{"subj":"T4","pred":"source","obj":"GO-MF"},{"subj":"T6","pred":"source","obj":"GO-MF"},{"subj":"T7","pred":"source","obj":"GO-MF"},{"subj":"T8","pred":"source","obj":"GO-MF"},{"subj":"T9","pred":"source","obj":"GO-MF"},{"subj":"T10","pred":"source","obj":"GO-MF"},{"subj":"T11","pred":"source","obj":"GO-MF"}]},{"project":"GO-CC","denotations":[{"id":"T8","span":{"begin":88,"end":92},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T9","span":{"begin":210,"end":214},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T10","span":{"begin":286,"end":290},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T17","span":{"begin":88,"end":100},"obj":"http://purl.obolibrary.org/obo/GO_0009986"}],"attributes":[{"subj":"T8","pred":"source","obj":"GO-CC"},{"subj":"T9","pred":"source","obj":"GO-CC"},{"subj":"T10","pred":"source","obj":"GO-CC"},{"subj":"T17","pred":"source","obj":"GO-CC"}]},{"project":"Lectin","denotations":[{"id":"Lectin_T2","span":{"begin":173,"end":181},"obj":"https://acgg.asia/db/lfdb/LfDB0013"},{"id":"Lectin_T3","span":{"begin":220,"end":228},"obj":"https://acgg.asia/db/lfdb/LfDB0013"},{"id":"Lectin_T4","span":{"begin":249,"end":257},"obj":"https://acgg.asia/db/lfdb/LfDB0013"},{"id":"Lectin_T6","span":{"begin":171,"end":181},"obj":"https://acgg.asia/db/lfdb/LfDB0043"},{"id":"Lectin_T7","span":{"begin":220,"end":228},"obj":"https://acgg.asia/db/lfdb/LfDB0043"},{"id":"Lectin_T8","span":{"begin":247,"end":257},"obj":"https://acgg.asia/db/lfdb/LfDB0043"},{"id":"Lectin_T10","span":{"begin":173,"end":181},"obj":"https://acgg.asia/db/lfdb/LfDB0142"},{"id":"Lectin_T11","span":{"begin":218,"end":228},"obj":"https://acgg.asia/db/lfdb/LfDB0142"},{"id":"Lectin_T12","span":{"begin":249,"end":257},"obj":"https://acgg.asia/db/lfdb/LfDB0142"}],"attributes":[{"subj":"Lectin_T2","pred":"source","obj":"Lectin"},{"subj":"Lectin_T3","pred":"source","obj":"Lectin"},{"subj":"Lectin_T4","pred":"source","obj":"Lectin"},{"subj":"Lectin_T6","pred":"source","obj":"Lectin"},{"subj":"Lectin_T7","pred":"source","obj":"Lectin"},{"subj":"Lectin_T8","pred":"source","obj":"Lectin"},{"subj":"Lectin_T10","pred":"source","obj":"Lectin"},{"subj":"Lectin_T11","pred":"source","obj":"Lectin"},{"subj":"Lectin_T12","pred":"source","obj":"Lectin"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"GlyCosmos6-UBERON","color":"#ecdc93","default":true},{"id":"Inflammaging","color":"#c293ec"},{"id":"PubMed_ArguminSci","color":"#93eca8"},{"id":"sentences","color":"#ec9397"},{"id":"mondo_disease","color":"#93b1ec"},{"id":"GlyCosmos6-CLO","color":"#cbec93"},{"id":"GlycoBiology-FMA","color":"#ec93e5"},{"id":"uniprot-human","color":"#93ecd8"},{"id":"uniprot-mouse","color":"#ecbe93"},{"id":"GO-BP","color":"#a493ec"},{"id":"GO-MF","color":"#9bec93"},{"id":"GO-CC","color":"#ec93b5"},{"id":"Lectin","color":"#93cfec"}]}]}}