PubMed:26116408
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 163-170 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T2 | 764-780 | https://glytoucan.org/Structures/Glycans/G71142DF | denotes | glucosylceramide |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 163-170 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T2 | 764-780 | Glycan_Motif | denotes | glucosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 163-170 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T2 | 764-780 | https://glytoucan.org/Structures/Glycans/G71142DF | denotes | glucosylceramide |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-121 | Sentence | denotes | Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae. |
| TextSentencer_T2 | 122-244 | Sentence | denotes | Sterylglucosides (SGs) are composed of a glucose and sterol derivatives, and are distributed in fungi, plants and mammals. |
| TextSentencer_T3 | 245-426 | Sentence | denotes | We recently identified EGCrP1 and EGCrP2 (endoglycoceramidase-related proteins 1 and 2) as a β-glucocerebrosidase and steryl-β-glucosidase, respectively, in Cryptococcus neoformans. |
| TextSentencer_T4 | 427-546 | Sentence | denotes | We herein describe an EGCrP2 homologue (Egh1; ORF name, Yir007w) involved in SG catabolism in Saccharomyces cerevisiae. |
| TextSentencer_T5 | 547-781 | Sentence | denotes | The purified recombinant Egh1 hydrolyzed various β-glucosides including ergosteryl β-glucoside (EG), cholesteryl β-glucoside, sitosteryl β-glucoside, para-nitrophenyl β-glucoside, 4-methylumberifellyl β-glucoside and glucosylceramide. |
| TextSentencer_T6 | 782-902 | Sentence | denotes | The disruption of EGH1 in S. cerevisiae BY4741 (egh1Δ) resulted in the accumulation of EG and fragmentation of vacuoles. |
| TextSentencer_T7 | 903-1019 | Sentence | denotes | The expression of EGH1 in egh1Δ (revertant) reduced the accumulation of EG, and restored the morphology of vacuoles. |
| TextSentencer_T8 | 1020-1205 | Sentence | denotes | The accumulation of EG was not detected in EGH1 and UGT51(ATG26) double-disrupted mutants (ugt51Δegh1Δ), indicating that EG was synthesized by Ugt51(Atg26) and degraded by Egh1 in vivo. |
| TextSentencer_T9 | 1206-1379 | Sentence | denotes | These results clearly demonstrated that Egh1 is an ergosteryl-β-glucosidase that is functionally involved in the EG catabolic pathway and vacuole formation in S. cerevisiae. |
| T1 | 0-121 | Sentence | denotes | Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae. |
| T2 | 122-244 | Sentence | denotes | Sterylglucosides (SGs) are composed of a glucose and sterol derivatives, and are distributed in fungi, plants and mammals. |
| T3 | 245-426 | Sentence | denotes | We recently identified EGCrP1 and EGCrP2 (endoglycoceramidase-related proteins 1 and 2) as a β-glucocerebrosidase and steryl-β-glucosidase, respectively, in Cryptococcus neoformans. |
| T4 | 427-546 | Sentence | denotes | We herein describe an EGCrP2 homologue (Egh1; ORF name, Yir007w) involved in SG catabolism in Saccharomyces cerevisiae. |
| T5 | 547-781 | Sentence | denotes | The purified recombinant Egh1 hydrolyzed various β-glucosides including ergosteryl β-glucoside (EG), cholesteryl β-glucoside, sitosteryl β-glucoside, para-nitrophenyl β-glucoside, 4-methylumberifellyl β-glucoside and glucosylceramide. |
| T6 | 782-902 | Sentence | denotes | The disruption of EGH1 in S. cerevisiae BY4741 (egh1Δ) resulted in the accumulation of EG and fragmentation of vacuoles. |
| T7 | 903-1019 | Sentence | denotes | The expression of EGH1 in egh1Δ (revertant) reduced the accumulation of EG, and restored the morphology of vacuoles. |
| T8 | 1020-1205 | Sentence | denotes | The accumulation of EG was not detected in EGH1 and UGT51(ATG26) double-disrupted mutants (ugt51Δegh1Δ), indicating that EG was synthesized by Ugt51(Atg26) and degraded by Egh1 in vivo. |
| T9 | 1206-1379 | Sentence | denotes | These results clearly demonstrated that Egh1 is an ergosteryl-β-glucosidase that is functionally involved in the EG catabolic pathway and vacuole formation in S. cerevisiae. |
| T1 | 0-121 | Sentence | denotes | Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae. |
| T2 | 122-244 | Sentence | denotes | Sterylglucosides (SGs) are composed of a glucose and sterol derivatives, and are distributed in fungi, plants and mammals. |
| T3 | 245-426 | Sentence | denotes | We recently identified EGCrP1 and EGCrP2 (endoglycoceramidase-related proteins 1 and 2) as a β-glucocerebrosidase and steryl-β-glucosidase, respectively, in Cryptococcus neoformans. |
| T4 | 427-546 | Sentence | denotes | We herein describe an EGCrP2 homologue (Egh1; ORF name, Yir007w) involved in SG catabolism in Saccharomyces cerevisiae. |
| T5 | 547-781 | Sentence | denotes | The purified recombinant Egh1 hydrolyzed various β-glucosides including ergosteryl β-glucoside (EG), cholesteryl β-glucoside, sitosteryl β-glucoside, para-nitrophenyl β-glucoside, 4-methylumberifellyl β-glucoside and glucosylceramide. |
| T6 | 782-902 | Sentence | denotes | The disruption of EGH1 in S. cerevisiae BY4741 (egh1Δ) resulted in the accumulation of EG and fragmentation of vacuoles. |
| T7 | 903-1019 | Sentence | denotes | The expression of EGH1 in egh1Δ (revertant) reduced the accumulation of EG, and restored the morphology of vacuoles. |
| T8 | 1020-1205 | Sentence | denotes | The accumulation of EG was not detected in EGH1 and UGT51(ATG26) double-disrupted mutants (ugt51Δegh1Δ), indicating that EG was synthesized by Ugt51(Atg26) and degraded by Egh1 in vivo. |
| T9 | 1206-1379 | Sentence | denotes | These results clearly demonstrated that Egh1 is an ergosteryl-β-glucosidase that is functionally involved in the EG catabolic pathway and vacuole formation in S. cerevisiae. |
GlycoBiology-PACDB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 96-120 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC297 | denotes | Saccharomyces cerevisiae |
| _T2 | 402-425 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC642 | denotes | Cryptococcus neoformans |
| _T3 | 402-425 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC597 | denotes | Cryptococcus neoformans |
| _T4 | 402-425 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC759 | denotes | Cryptococcus neoformans |
| _T5 | 521-545 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC297 | denotes | Saccharomyces cerevisiae |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 140-143 | FMAID:177391 | denotes | SGs |
| _T2 | 163-170 | FMAID:82743 | denotes | glucose |
| _T3 | 163-170 | FMAID:196732 | denotes | glucose |
| _T4 | 225-231 | FMAID:214748 | denotes | plants |
| _T5 | 315-323 | FMAID:165447 | denotes | proteins |
| _T6 | 315-323 | FMAID:67257 | denotes | proteins |
| _T7 | 504-506 | FMAID:177391 | denotes | SG |
| _T8 | 764-780 | FMAID:82820 | denotes | glucosylceramide |
| _T9 | 764-780 | FMAID:196816 | denotes | glucosylceramide |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 307-325 | http://www.uniprot.org/uniprot/O43423 | denotes | related proteins 1 |
| T2 | 307-325 | http://www.uniprot.org/uniprot/Q9P2R6 | denotes | related proteins 1 |
| T3 | 307-325 | http://www.uniprot.org/uniprot/P55209 | denotes | related proteins 1 |
| T4 | 307-325 | http://www.uniprot.org/uniprot/P22004 | denotes | related proteins 1 |
| T5 | 307-325 | http://www.uniprot.org/uniprot/Q01085 | denotes | related proteins 1 |
| T6 | 307-325 | http://www.uniprot.org/uniprot/Q8N5K1 | denotes | related proteins 1 |
| T7 | 307-325 | http://www.uniprot.org/uniprot/P09544 | denotes | related proteins 1 |
| T8 | 307-325 | http://www.uniprot.org/uniprot/Q9NZH6 | denotes | related proteins 1 |
| T9 | 307-325 | http://www.uniprot.org/uniprot/Q9UH17 | denotes | related proteins 1 |
| T10 | 307-325 | http://www.uniprot.org/uniprot/O75956 | denotes | related proteins 1 |
| T11 | 330-358 | http://www.uniprot.org/uniprot/Q9HCG7 | denotes | 2) as a β-glucocerebrosidase |
| T12 | 338-358 | http://www.uniprot.org/uniprot/Q6I9R6 | denotes | β-glucocerebrosidase |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 330-358 | http://www.uniprot.org/uniprot/Q69ZF3 | denotes | 2) as a β-glucocerebrosidase |
| T2 | 338-358 | http://www.uniprot.org/uniprot/P17439 | denotes | β-glucocerebrosidase |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 96-109 | http://purl.bioontology.org/ontology/NCBITAXON/4891 | denotes | Saccharomyces |
| T2 | 96-109 | http://purl.bioontology.org/ontology/NCBITAXON/4895 | denotes | Saccharomyces |
| T3 | 96-109 | http://purl.bioontology.org/ontology/NCBITAXON/36034 | denotes | Saccharomyces |
| T4 | 96-109 | http://purl.bioontology.org/ontology/NCBITAXON/4930 | denotes | Saccharomyces |
| T5 | 236-243 | http://purl.bioontology.org/ontology/STY/T015 | denotes | mammals |
| T6 | 307-314 | http://purl.bioontology.org/ontology/NCBITAXON/353209 | denotes | related |
| T7 | 402-414 | http://purl.bioontology.org/ontology/NCBITAXON/106841 | denotes | Cryptococcus |
| T8 | 402-414 | http://purl.bioontology.org/ontology/NCBITAXON/89915 | denotes | Cryptococcus |
| T9 | 402-414 | http://purl.bioontology.org/ontology/NCBITAXON/561281 | denotes | Cryptococcus |
| T10 | 402-414 | http://purl.bioontology.org/ontology/NCBITAXON/104409 | denotes | Cryptococcus |
| T11 | 402-414 | http://purl.bioontology.org/ontology/NCBITAXON/214992 | denotes | Cryptococcus |
| T12 | 402-414 | http://purl.bioontology.org/ontology/NCBITAXON/107441 | denotes | Cryptococcus |
| T13 | 521-534 | http://purl.bioontology.org/ontology/NCBITAXON/36034 | denotes | Saccharomyces |
| T14 | 521-534 | http://purl.bioontology.org/ontology/NCBITAXON/4891 | denotes | Saccharomyces |
| T15 | 521-534 | http://purl.bioontology.org/ontology/NCBITAXON/4930 | denotes | Saccharomyces |
| T16 | 521-534 | http://purl.bioontology.org/ontology/NCBITAXON/4895 | denotes | Saccharomyces |
| T17 | 697-701 | http://purl.bioontology.org/ontology/NCBITAXON/218705 | denotes | para |
| T18 | 697-701 | http://purl.bioontology.org/ontology/NCBITAXON/507091 | denotes | para |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 60-70 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | catabolism |
| T2 | 507-517 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | catabolism |
| T3 | 1322-1331 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | catabolic |
| T4 | 83-92 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T5 | 1352-1361 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T6 | 1180-1188 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degraded |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 75-82 | http://purl.obolibrary.org/obo/GO_0005773 | denotes | vacuole |
| T2 | 893-901 | http://purl.obolibrary.org/obo/GO_0005773 | denotes | vacuoles |
| T3 | 1010-1018 | http://purl.obolibrary.org/obo/GO_0005773 | denotes | vacuoles |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 218-223 | http://edamontology.org/topic_0782 | denotes | fungi |
| T2 | 225-231 | http://edamontology.org/topic_0780 | denotes | plants |
| T3 | 236-243 | http://edamontology.org/topic_3048 | denotes | mammals |
| T4 | 315-323 | http://edamontology.org/topic_0078 | denotes | proteins |
| T5 | 1322-1339 | http://edamontology.org/topic_0753 | denotes | catabolic pathway |
| T6 | 1332-1339 | http://edamontology.org/topic_0602 | denotes | pathway |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 83-92 | http://edamontology.org/format_1915 | denotes | formation |
| T2 | 83-92 | http://edamontology.org/operation_0335 | denotes | formation |
| T3 | 257-267 | http://edamontology.org/data_2611 | denotes | identified |
| T4 | 257-267 | http://edamontology.org/data_0842 | denotes | identified |
| T5 | 315-323 | http://edamontology.org/format_1208 | denotes | proteins |
| T6 | 315-323 | http://edamontology.org/data_1467 | denotes | proteins |
| T7 | 473-481 | http://edamontology.org/data_1807 | denotes | ORF name |
| T8 | 477-481 | http://edamontology.org/data_2099 | denotes | name |
| T9 | 1051-1059 | http://edamontology.org/operation_2423 | denotes | detected |
| T10 | 1228-1240 | http://edamontology.org/operation_2246 | denotes | demonstrated |
| T11 | 1290-1302 | http://edamontology.org/operation_0004 | denotes | functionally |
| T12 | 1332-1339 | http://edamontology.org/data_2600 | denotes | pathway |
| T13 | 1352-1361 | http://edamontology.org/operation_0335 | denotes | formation |
| T14 | 1352-1361 | http://edamontology.org/format_1915 | denotes | formation |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 96-120 | OrganismTaxon | denotes | Saccharomyces cerevisiae | 4932 |
| T2 | 218-223 | OrganismTaxon | denotes | fungi | 4751 |
| T3 | 402-425 | OrganismTaxon | denotes | Cryptococcus neoformans | 5207 |
| T4 | 521-545 | OrganismTaxon | denotes | Saccharomyces cerevisiae | 4932 |
| T5 | 808-821 | OrganismTaxon | denotes | S. cerevisiae | 4932 |
| T6 | 1365-1378 | OrganismTaxon | denotes | S. cerevisiae | 4932 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 75-82 | Body_part | denotes | vacuole | http://purl.obolibrary.org/obo/GO_0005773 |
| T2 | 1344-1351 | Body_part | denotes | vacuole | http://purl.obolibrary.org/obo/GO_0005773 |