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PubMed:26115410 JSONTXT

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LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 1314-1319 OrganismTaxon denotes human NCBItxid:9606

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-86 Sentence denotes Mechanisms Underlying Latent Disease Risk Associated with Early-Life Arsenic Exposure:
T2 87-131 Sentence denotes Current Research Trends and Scientific Gaps.
T3 132-143 Sentence denotes BACKGROUND:
T4 144-317 Sentence denotes Millions of individuals worldwide, particularly those living in rural and developing areas, are exposed to harmful levels of inorganic arsenic (iAs) in their drinking water.
T5 318-474 Sentence denotes Inorganic As exposure during key developmental periods is associated with a variety of adverse health effects including those that are evident in adulthood.
T6 475-666 Sentence denotes There is considerable interest in identifying the molecular mechanisms that relate early-life iAs exposure to the development of these latent diseases, particularly in relationship to cancer.
T7 667-678 Sentence denotes OBJECTIVES:
T8 679-853 Sentence denotes This work summarizes research on the molecular mechanisms that underlie the increased risk of cancer development in adulthood that is associated with early-life iAs exposure.
T9 854-865 Sentence denotes DISCUSSION:
T10 866-1107 Sentence denotes Epigenetic reprogramming that imparts functional changes in gene expression, the development of cancer stem cells, and immunomodulation are plausible underlying mechanisms by which early-life iAs exposure elicits latent carcinogenic effects.
T11 1108-1120 Sentence denotes CONCLUSIONS:
T12 1121-1216 Sentence denotes Evidence is mounting that relates early-life iAs exposure and cancer development later in life.
T13 1217-1419 Sentence denotes Future research should include animal studies that address mechanistic hypotheses and studies of human populations that integrate early-life exposure, molecular alterations, and latent disease outcomes.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
10737 69-76 ChemicalEntity denotes Arsenic MESH:D001151
10738 269-286 ChemicalEntity denotes inorganic arsenic MESH:D001152
10739 288-291 ChemicalEntity denotes iAs MESH:D001152
10740 318-330 ChemicalEntity denotes Inorganic As MESH:D001152
10741 569-572 ChemicalEntity denotes iAs MESH:D001152
10742 659-665 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
10743 773-779 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
10744 840-843 ChemicalEntity denotes iAs MESH:D001152
10745 962-968 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
10746 1058-1061 ChemicalEntity denotes iAs MESH:D001152
10747 1086-1098 DiseaseOrPhenotypicFeature denotes carcinogenic MESH:D009369
10748 1166-1169 ChemicalEntity denotes iAs MESH:D001152
10749 1183-1189 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
10750 1314-1319 OrganismTaxon denotes human NCBITaxon:9606

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 659-665 DiseaseOrPhenotypicFeature denotes cancer 0004992
T2 773-779 DiseaseOrPhenotypicFeature denotes cancer 0004992
T3 962-968 DiseaseOrPhenotypicFeature denotes cancer 0004992
T4 1183-1189 DiseaseOrPhenotypicFeature denotes cancer 0004992

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 58-63 GeneOrGeneProduct denotes Early
T2 126-130 GeneOrGeneProduct denotes Gaps
T3 558-563 GeneOrGeneProduct denotes early
T4 829-834 GeneOrGeneProduct denotes early
T5 1047-1052 GeneOrGeneProduct denotes early
T6 1155-1160 GeneOrGeneProduct denotes early
T7 1347-1352 GeneOrGeneProduct denotes early

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 58-63 GeneOrGeneProduct denotes Early
T2 126-130 GeneOrGeneProduct denotes Gaps
T3 229-234 GeneOrGeneProduct denotes areas
T4 365-372 GeneOrGeneProduct denotes periods
T5 558-563 GeneOrGeneProduct denotes early
T6 829-834 GeneOrGeneProduct denotes early
T7 974-979 GeneOrGeneProduct denotes cells
T8 1047-1052 GeneOrGeneProduct denotes early
T9 1155-1160 GeneOrGeneProduct denotes early
T10 1202-1207 GeneOrGeneProduct denotes later
T11 1347-1352 GeneOrGeneProduct denotes early

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 29-36 DiseaseOrPhenotypicFeature denotes Disease D004194
T2 617-625 DiseaseOrPhenotypicFeature denotes diseases D004194
T3 659-665 DiseaseOrPhenotypicFeature denotes cancer D009369
T4 773-779 DiseaseOrPhenotypicFeature denotes cancer D009369
T5 962-968 DiseaseOrPhenotypicFeature denotes cancer D009369
T6 1183-1189 DiseaseOrPhenotypicFeature denotes cancer D009369
T7 1402-1409 DiseaseOrPhenotypicFeature denotes disease D004194

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 126-130 GeneOrGeneProduct denotes Gaps

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 29-36 DiseaseOrPhenotypicFeature denotes Disease D004194
T2 617-625 DiseaseOrPhenotypicFeature denotes diseases D004194
T3 659-665 DiseaseOrPhenotypicFeature denotes cancer D009369
T4 773-779 DiseaseOrPhenotypicFeature denotes cancer D009369
T5 962-968 DiseaseOrPhenotypicFeature denotes cancer D009369
T6 1086-1098 DiseaseOrPhenotypicFeature denotes carcinogenic DISEASE
T7 1183-1189 DiseaseOrPhenotypicFeature denotes cancer D009369
T8 1402-1409 DiseaseOrPhenotypicFeature denotes disease D004194

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 659-665 DiseaseOrPhenotypicFeature denotes cancer D009369
T2 773-779 DiseaseOrPhenotypicFeature denotes cancer D009369
T3 962-968 DiseaseOrPhenotypicFeature denotes cancer D009369
T4 1086-1098 DiseaseOrPhenotypicFeature denotes carcinogenic DISEASE
T5 1183-1189 DiseaseOrPhenotypicFeature denotes cancer D009369

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 69-76 ChemicalEntity denotes Arsenic http://purl.obolibrary.org/obo/CHEBI_27563
T2 279-286 ChemicalEntity denotes arsenic D001151|http://purl.obolibrary.org/obo/CHEBI_27563
T4 288-291 ChemicalEntity denotes iAs ChemicalEntity
T5 302-316 ChemicalEntity denotes drinking water D060766
T6 318-330 ChemicalEntity denotes Inorganic As ChemicalEntity
T7 569-572 ChemicalEntity denotes iAs ChemicalEntity
T8 840-843 ChemicalEntity denotes iAs ChemicalEntity
T9 1058-1061 ChemicalEntity denotes iAs ChemicalEntity
T10 1166-1169 ChemicalEntity denotes iAs ChemicalEntity

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 0-10 OrganismTaxon denotes Mechanisms
T2 1314-1319 OrganismTaxon denotes human

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T10 1166-1169 ChemicalEntity denotes iAs ChemicalEntity
T9 1058-1061 ChemicalEntity denotes iAs ChemicalEntity
T8 840-843 ChemicalEntity denotes iAs ChemicalEntity
T7 569-572 ChemicalEntity denotes iAs ChemicalEntity
T6 318-330 ChemicalEntity denotes Inorganic As ChemicalEntity
T5 302-316 ChemicalEntity denotes drinking water D060766
T4 288-291 ChemicalEntity denotes iAs ChemicalEntity
T2 279-286 ChemicalEntity denotes arsenic http://purl.obolibrary.org/obo/CHEBI_27563|D001151
T1 69-76 ChemicalEntity denotes Arsenic http://purl.obolibrary.org/obo/CHEBI_27563
T90943 126-130 GeneOrGeneProduct denotes Gaps
T65479 1183-1189 DiseaseOrPhenotypicFeature denotes cancer D009369
T86019 1086-1098 DiseaseOrPhenotypicFeature denotes carcinogenic DISEASE
T3 962-968 DiseaseOrPhenotypicFeature denotes cancer D009369
T22490 773-779 DiseaseOrPhenotypicFeature denotes cancer D009369
T90962 659-665 DiseaseOrPhenotypicFeature denotes cancer D009369
T9977 1314-1319 OrganismTaxon denotes human
T23912 0-10 OrganismTaxon denotes Mechanisms