PubMed:26102294 / 1183-1465 JSONTXT

{"project":"LitCoin-sentences","denotations":[{"id":"T8","span":{"begin":0,"end":282},"obj":"Sentence"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}

{"project":"LitCoin-entities","denotations":[{"id":"10727","span":{"begin":9,"end":12},"obj":"ChemicalEntity"},{"id":"10728","span":{"begin":21,"end":26},"obj":"GeneOrGeneProduct"},{"id":"10729","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"10730","span":{"begin":130,"end":138},"obj":"GeneOrGeneProduct"},{"id":"10731","span":{"begin":231,"end":234},"obj":"ChemicalEntity"}],"attributes":[{"id":"A24","pred":"db_id","subj":"10727","obj":"MESH:D005047"},{"id":"A25","pred":"db_id","subj":"10728","obj":"NCBIGene:5460"},{"id":"A26","pred":"db_id","subj":"10729","obj":"NCBIGene:5562"},{"id":"A27","pred":"db_id","subj":"10730","obj":"NCBIGene:1029"},{"id":"A28","pred":"db_id","subj":"10731","obj":"MESH:D005047"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T13","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":108,"end":117},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":130,"end":138},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":271,"end":275},"obj":"GeneOrGeneProduct"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T25","span":{"begin":13,"end":20},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":48,"end":58},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":108,"end":117},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":118,"end":128},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":130,"end":138},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":144,"end":151},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":218,"end":227},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":243,"end":248},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":271,"end":275},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":276,"end":281},"obj":"GeneOrGeneProduct"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T8","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":130,"end":138},"obj":"GeneOrGeneProduct"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}

{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T12","span":{"begin":9,"end":12},"obj":"ChemicalEntity"},{"id":"T14","span":{"begin":231,"end":234},"obj":"ChemicalEntity"}],"attributes":[{"id":"A12","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_27561"},{"id":"A13","pred":"ID:","subj":"T12","obj":"D005047"},{"id":"A14","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_27561"},{"id":"A15","pred":"ID:","subj":"T14","obj":"D005047"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T14","span":{"begin":231,"end":234},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":9,"end":12},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":130,"end":138},"obj":"GeneOrGeneProduct"},{"id":"T98634","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A15","pred":"ID:","subj":"T14","obj":"D005047"},{"id":"A14","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_27561"},{"id":"A13","pred":"ID:","subj":"T12","obj":"D005047"},{"id":"A12","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_27561"}],"text":"Instead, ETO-induced OCT4A was concomitant with activation of AMPK, a key component of metabolic stress and autophagy regulation. p16ink4a, the inducer of terminal senescence, underwent autophagic sequestration in the cytoplasm of ETO-treated cells, allowing alternative cell fates."}