PubMed:25979836 / 1234-1419 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/25979836","sourcedb":"PubMed","sourceid":"25979836","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/25979836","text":"IPA-3, which prevents PAK2 binding to small-GTPases partially inhibited PAK2-activation, as well as reduced CCK-induced ERK1/2 activation and amylase release induced by CCK or bombesin.","tracks":[{"project":"LitCoin-sentences","denotations":[{"id":"T9","span":{"begin":0,"end":185},"obj":"Sentence"}],"attributes":[{"subj":"T9","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin-entities","denotations":[{"id":"10674","span":{"begin":0,"end":5},"obj":"ChemicalEntity"},{"id":"10675","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"10676","span":{"begin":38,"end":51},"obj":"GeneOrGeneProduct"},{"id":"10677","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"10678","span":{"begin":108,"end":111},"obj":"GeneOrGeneProduct"},{"id":"10679","span":{"begin":120,"end":126},"obj":"GeneOrGeneProduct"},{"id":"10680","span":{"begin":142,"end":149},"obj":"GeneOrGeneProduct"},{"id":"10681","span":{"begin":169,"end":172},"obj":"GeneOrGeneProduct"},{"id":"10682","span":{"begin":176,"end":184},"obj":"ChemicalEntity"}],"attributes":[{"id":"A68","pred":"db_id","subj":"10674","obj":"MESH:C541795"},{"id":"A69","pred":"db_id","subj":"10675","obj":"NCBIGene:29432"},{"id":"A70","pred":"db_id","subj":"10676","obj":"NCBIGene:363875"},{"id":"A71","pred":"db_id","subj":"10676","obj":"NCBIGene:64465"},{"id":"A72","pred":"db_id","subj":"10677","obj":"NCBIGene:29432"},{"id":"A73","pred":"db_id","subj":"10678","obj":"NCBIGene:25298"},{"id":"A74","pred":"db_id","subj":"10679","obj":"NCBIGene:116590"},{"id":"A75","pred":"db_id","subj":"10679","obj":"NCBIGene:50689"},{"id":"A76","pred":"db_id","subj":"10680","obj":"NCBIGene:24203"},{"id":"A77","pred":"db_id","subj":"10681","obj":"NCBIGene:25298"},{"id":"A78","pred":"db_id","subj":"10682","obj":"MESH:D001839"},{"subj":"10674","pred":"source","obj":"LitCoin-entities"},{"subj":"10675","pred":"source","obj":"LitCoin-entities"},{"subj":"10676","pred":"source","obj":"LitCoin-entities"},{"subj":"10677","pred":"source","obj":"LitCoin-entities"},{"subj":"10678","pred":"source","obj":"LitCoin-entities"},{"subj":"10679","pred":"source","obj":"LitCoin-entities"},{"subj":"10680","pred":"source","obj":"LitCoin-entities"},{"subj":"10681","pred":"source","obj":"LitCoin-entities"},{"subj":"10682","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T37","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":27,"end":34},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":38,"end":43},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":100,"end":107},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":120,"end":126},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":142,"end":149},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":176,"end":184},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T37","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T38","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T39","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T40","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T41","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T42","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T43","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T44","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T55","span":{"begin":0,"end":3},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T57","span":{"begin":27,"end":34},"obj":"GeneOrGeneProduct"},{"id":"T58","span":{"begin":38,"end":43},"obj":"GeneOrGeneProduct"},{"id":"T59","span":{"begin":44,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T60","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T61","span":{"begin":77,"end":87},"obj":"GeneOrGeneProduct"},{"id":"T62","span":{"begin":100,"end":107},"obj":"GeneOrGeneProduct"},{"id":"T63","span":{"begin":112,"end":119},"obj":"GeneOrGeneProduct"},{"id":"T64","span":{"begin":120,"end":126},"obj":"GeneOrGeneProduct"},{"id":"T65","span":{"begin":127,"end":137},"obj":"GeneOrGeneProduct"},{"id":"T66","span":{"begin":142,"end":149},"obj":"GeneOrGeneProduct"},{"id":"T67","span":{"begin":158,"end":165},"obj":"GeneOrGeneProduct"},{"id":"T68","span":{"begin":176,"end":184},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T55","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T56","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T57","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T58","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T59","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T60","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T61","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T62","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T63","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T64","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T65","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T66","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T67","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T68","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T24","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":38,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":120,"end":126},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":142,"end":149},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T2","span":{"begin":0,"end":3},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0010302"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T29","span":{"begin":0,"end":5},"obj":"ChemicalEntity"},{"id":"T30","span":{"begin":44,"end":51},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":142,"end":149},"obj":"ChemicalEntity"},{"id":"T32","span":{"begin":176,"end":184},"obj":"ChemicalEntity"}],"attributes":[{"id":"A29","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_101355"},{"id":"A30","pred":"ID:","subj":"T30","obj":"D020558"},{"id":"A31","pred":"ID:","subj":"T31","obj":"D000681"},{"id":"A32","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_80229"},{"subj":"T29","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T30","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T31","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T32","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T2","span":{"begin":0,"end":3},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T32","span":{"begin":176,"end":184},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":142,"end":149},"obj":"ChemicalEntity"},{"id":"T30","span":{"begin":44,"end":51},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":0,"end":5},"obj":"ChemicalEntity"},{"id":"T28","span":{"begin":142,"end":149},"obj":"GeneOrGeneProduct"},{"id":"T18931","span":{"begin":120,"end":126},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T85992","span":{"begin":38,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":22,"end":26},"obj":"GeneOrGeneProduct"},{"id":"T26555","span":{"begin":0,"end":3},"obj":"OrganismTaxon"}],"attributes":[{"id":"A32","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_80229"},{"id":"A31","pred":"ID:","subj":"T31","obj":"D000681"},{"id":"A30","pred":"ID:","subj":"T30","obj":"D020558"},{"id":"A29","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_101355"},{"subj":"T32","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T31","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T30","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T29","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T28","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T18931","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T26","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T85992","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T24","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T26555","pred":"source","obj":"LitCoin-training-merged"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCoin-sentences","color":"#93ecd4","default":true},{"id":"LitCoin-entities","color":"#ecba93"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#a093ec"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#9fec93"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#ec93b9"},{"id":"LitCoin_Mondo_095","color":"#93d3ec"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#ecea93"},{"id":"LitCoin-NCBITaxon-2","color":"#d093ec"},{"id":"LitCoin-training-merged","color":"#93ecb6"}]}]}}