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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 108-122 https://glytoucan.org/Structures/Glycans/G00053MO denotes sialyl Lewis a
T2 108-122 https://glytoucan.org/Structures/Glycans/G81971FM denotes sialyl Lewis a
T3 745-751 https://glytoucan.org/Structures/Glycans/G00053MO denotes sLe(a)
T4 950-956 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLe(x)

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 108-122 Glycan_Motif denotes sialyl Lewis a https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81971FM|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00053MO
T3 115-122 Glycan_Motif denotes Lewis a https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G39023AU|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00047MO
T5 745-751 Glycan_Motif denotes sLe(a) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00053MO
T6 950-956 Glycan_Motif denotes sLe(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 108-122 https://glytoucan.org/Structures/Glycans/G00053MO denotes sialyl Lewis a
T2 108-122 https://glytoucan.org/Structures/Glycans/G81971FM denotes sialyl Lewis a
T3 115-122 https://glytoucan.org/Structures/Glycans/G00047MO denotes Lewis a
T4 115-122 https://glytoucan.org/Structures/Glycans/G39023AU denotes Lewis a
T5 745-751 https://glytoucan.org/Structures/Glycans/G00053MO denotes sLe(a)
T6 950-956 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLe(x)

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
TextSentencer_T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
TextSentencer_T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
TextSentencer_T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
TextSentencer_T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
TextSentencer_T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
TextSentencer_T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
TextSentencer_T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
TextSentencer_T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
TextSentencer_T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.
T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.
T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 108-122 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl Lewis a
T2 115-122 http://www.glycoepitope.jp/epitopes/EP0007 denotes Lewis a

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 599-608 http://purl.obolibrary.org/obo/MAT_0000491 denotes proximity
T2 879-883 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T3 1020-1024 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 86-94 FMAID:165243 denotes selectin
_T2 86-94 FMAID:61795 denotes selectin
_T3 177-184 FMAID:146300 denotes surface
_T4 177-184 FMAID:50594 denotes surface
_T5 177-199 FMAID:165570 denotes surface of tumor cells
_T6 177-199 FMAID:67653 denotes surface of tumor cells
_T7 194-199 FMAID:169002 denotes cells
_T8 194-199 FMAID:68646 denotes cells
_T9 374-387 FMAID:62925 denotes glycoproteins
_T10 374-387 FMAID:167256 denotes glycoproteins
_T11 405-417 FMAID:197276 denotes carbohydrate
_T12 405-417 FMAID:82737 denotes carbohydrate
_T13 468-476 FMAID:165243 denotes selectin
_T14 468-476 FMAID:61795 denotes selectin
_T15 599-608 FMAID:30326 denotes proximity
_T16 599-608 FMAID:171415 denotes proximity
_T17 760-765 FMAID:68646 denotes cells
_T18 760-765 FMAID:169002 denotes cells
_T19 843-869 FMAID:200944 denotes bronchial epithelial cells
_T20 853-869 FMAID:169652 denotes epithelial cells
_T21 853-869 FMAID:66768 denotes epithelial cells
_T22 853-869 FMAID:165731 denotes epithelial cells
_T23 853-869 FMAID:83514 denotes epithelial cells
_T24 853-869 FMAID:69074 denotes epithelial cells
_T25 853-869 FMAID:67559 denotes epithelial cells
_T26 853-869 FMAID:67799 denotes epithelial cells
_T27 853-869 FMAID:165528 denotes epithelial cells
_T28 853-869 FMAID:169653 denotes epithelial cells
_T29 853-869 FMAID:69075 denotes epithelial cells
_T30 853-869 FMAID:164922 denotes epithelial cells
_T31 853-869 FMAID:197786 denotes epithelial cells
_T32 864-869 FMAID:169002 denotes cells
_T33 864-869 FMAID:68646 denotes cells
_T34 879-883 FMAID:169341 denotes lung
_T35 879-883 FMAID:93670 denotes lung
_T36 879-883 FMAID:7195 denotes lung
_T37 894-899 FMAID:169002 denotes cells
_T38 894-899 FMAID:68646 denotes cells
_T39 984-1010 FMAID:200944 denotes bronchial epithelial cells
_T40 994-1010 FMAID:66768 denotes epithelial cells
_T41 994-1010 FMAID:83514 denotes epithelial cells
_T42 994-1010 FMAID:197786 denotes epithelial cells
_T43 994-1010 FMAID:165528 denotes epithelial cells
_T44 994-1010 FMAID:164922 denotes epithelial cells
_T45 994-1010 FMAID:169653 denotes epithelial cells
_T46 994-1010 FMAID:69075 denotes epithelial cells
_T47 994-1010 FMAID:69074 denotes epithelial cells
_T48 994-1010 FMAID:169652 denotes epithelial cells
_T49 994-1010 FMAID:165731 denotes epithelial cells
_T50 994-1010 FMAID:67799 denotes epithelial cells
_T51 994-1010 FMAID:67559 denotes epithelial cells
_T52 1005-1010 FMAID:68646 denotes cells
_T53 1005-1010 FMAID:169002 denotes cells
_T54 1020-1024 FMAID:93670 denotes lung
_T55 1020-1024 FMAID:7195 denotes lung
_T56 1020-1024 FMAID:169341 denotes lung
_T57 1035-1040 FMAID:169002 denotes cells
_T58 1035-1040 FMAID:68646 denotes cells
_T59 1050-1058 FMAID:165243 denotes selectin
_T60 1050-1058 FMAID:61795 denotes selectin
_T61 1103-1108 FMAID:169002 denotes cells
_T62 1103-1108 FMAID:68646 denotes cells
_T63 1163-1171 FMAID:165243 denotes selectin
_T64 1163-1171 FMAID:61795 denotes selectin
_T65 1213-1218 FMAID:169002 denotes cells
_T66 1213-1218 FMAID:68646 denotes cells
_T67 1397-1405 FMAID:61795 denotes selectin
_T68 1397-1405 FMAID:165243 denotes selectin
_T69 1454-1459 FMAID:68646 denotes cells
_T70 1454-1459 FMAID:169002 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 728-733 http://www.uniprot.org/uniprot/Q8WXI7 denotes MUC16
T2 934-938 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1
T3 1078-1082 http://www.uniprot.org/uniprot/Q9BXA4 denotes MUC1

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 194-199 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T2 486-492 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T3 760-765 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T4 864-869 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T5 884-893 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T6 894-899 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T7 1005-1010 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T8 1025-1034 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T9 1035-1040 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T10 1103-1108 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T11 1213-1218 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T12 1273-1281 http://purl.bioontology.org/ontology/NCBITAXON/871272 denotes parallel
T13 1447-1453 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T14 1454-1459 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 37-46 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T2 234-243 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T3 715-724 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T4 921-930 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T5 1367-1376 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T6 108-114 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T7 634-650 http://purl.obolibrary.org/obo/GO_0016246 denotes interference RNA
T8 1255-1268 http://purl.obolibrary.org/obo/GO_0042060 denotes wound healing
T9 1467-1476 http://purl.obolibrary.org/obo/GO_0065007 denotes regulated
T10 1546-1553 http://purl.obolibrary.org/obo/GO_0032502 denotes develop

GO-MF

Id Subject Object Predicate Lexical cue
T1 86-94 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T2 468-476 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T3 1050-1058 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T4 1163-1171 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T5 1397-1405 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T6 95-102 http://purl.obolibrary.org/obo/GO_0005488 denotes ligands
T7 1059-1065 http://purl.obolibrary.org/obo/GO_0005488 denotes ligand

GO-CC

Id Subject Object Predicate Lexical cue
T1 194-199 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 760-765 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 864-869 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 894-899 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5 1005-1010 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T6 1035-1040 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T7 1103-1108 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8 1213-1218 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9 1454-1459 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 879-883 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T2 1020-1024 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 599-608 http://purl.obolibrary.org/obo/MAT_0000491 denotes proximity
T2 879-883 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T3 1020-1024 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 108-120 http://rdf.glycoinfo.org/glycan/G00053MO denotes sialyl Lewis
T2 115-120 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T3 950-955 http://rdf.glycoinfo.org/glycan/G00054MO denotes sLe(x

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 86-94 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T2 468-476 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T3 1050-1058 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T4 1163-1171 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T5 1397-1405 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T6 86-94 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T7 468-476 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T8 1050-1058 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T9 1163-1171 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T10 1397-1405 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T11 86-94 https://acgg.asia/db/lfdb/LfDB0142 denotes selectin
Lectin_T12 468-476 https://acgg.asia/db/lfdb/LfDB0142 denotes selectin
Lectin_T13 1050-1058 https://acgg.asia/db/lfdb/LfDB0142 denotes selectin
Lectin_T14 1163-1171 https://acgg.asia/db/lfdb/LfDB0142 denotes selectin
Lectin_T15 1397-1405 https://acgg.asia/db/lfdb/LfDB0142 denotes selectin

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 108-122 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl Lewis a
PD-GlycoEpitope-B_T2 115-122 http://www.glycoepitope.jp/epitopes/EP0007 denotes Lewis a

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 879-883 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 1020-1024 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 188-193 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T2 486-492 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T3 879-893 Disease denotes lung carcinoma http://purl.obolibrary.org/obo/MONDO_0005138
T4 1020-1034 Disease denotes lung carcinoma http://purl.obolibrary.org/obo/MONDO_0005138
T5 1255-1260 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T6 1447-1453 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 108-122 Glycan denotes sialyl Lewis a https://api.glycosmos.org/wurcs2image/latest/png/binary/G00053MO

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 108-122 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis a http://www.glycoepitope.jp/epitopes/EP0008

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 188-193 Phenotype denotes tumor HP:0002664
T2 486-492 Phenotype denotes cancer HP:0002664
T3 884-893 Phenotype denotes carcinoma HP:0030731
T4 1025-1034 Phenotype denotes carcinoma HP:0030731
T5 1447-1453 Phenotype denotes cancer HP:0002664

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 188-193 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T2 486-492 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T3 879-893 Disease denotes lung carcinoma http://purl.obolibrary.org/obo/MONDO_0005138
T4 1020-1034 Disease denotes lung carcinoma http://purl.obolibrary.org/obo/MONDO_0005138
T5 1255-1260 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T6 1447-1453 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 824-829 OrganismTaxon denotes human 9606
T2 965-970 OrganismTaxon denotes human 9606

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 188-199 Cell denotes tumor cells http://purl.obolibrary.org/obo/CL:0001063
T2 843-869 Cell denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL:0002328
T3 984-1010 Cell denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL:0002328
T4 1447-1459 Cell denotes cancer cells http://purl.obolibrary.org/obo/CL:0001064

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 843-869 Body_part denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL_0002328
T2 879-883 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 984-1010 Body_part denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL_0002328
T4 1020-1024 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 1282-1287 Body_part denotes plate http://purl.obolibrary.org/obo/UBERON_6004475

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 599-608 Body_part denotes proximity http://purl.obolibrary.org/obo/MAT_0000491
T2 879-883 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T3 1020-1024 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
TextSentencer_T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
TextSentencer_T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
TextSentencer_T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
TextSentencer_T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
TextSentencer_T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
TextSentencer_T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
TextSentencer_T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
TextSentencer_T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
TextSentencer_T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.
T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.
T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.
T2 104-227 Sentence denotes The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis.
T3 228-320 Sentence denotes Their synthesis has been attributed to altered expression of selective glycosyltransferases.
T4 321-504 Sentence denotes Identification of these glycosyltransferases and the glycoproteins that carry these carbohydrate antigens should help advance our understanding of selectin-mediated cancer metastasis.
T5 505-766 Sentence denotes In this study, quantitative real-time polymerase chain reaction analysis coupled with in situ proximity ligation assay and small interference RNA treatment shows involvement of β3galactosyltransferase-V in the synthesis of MUC16-associated sLe(a) in H292 cells.
T6 767-1041 Sentence denotes Also, α3fucosyltransferase-V, which is absent in BEAS-2B human immortalized bronchial epithelial cells and A549 lung carcinoma cells, participates in the synthesis of MUC1-associated sLe(x) in CFT1 human immortalized bronchial epithelial cells and H292 lung carcinoma cells.
T7 1042-1109 Sentence denotes Neither selectin ligand is found on MUC1 in BEAS-2B and A549 cells.
T8 1110-1322 Sentence denotes Knockdown of either enzyme suppresses migration, and selectin tethering and rolling properties of H292 cells under dynamic flow as determined by wound healing and parallel plate flow chamber assays, respectively.
T9 1323-1531 Sentence denotes These results provide insights into how the synthesis of mucin-associated selectin ligands and the metastatic properties of cancer cells can be regulated by selective glycosyltransferases that work on mucins.
T10 1532-1577 Sentence denotes They may help develop novel anticancer drugs.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 108-122 Glycan denotes sialyl Lewis a https://api.glycosmos.org/wurcs2image/latest/png/binary/G00053MO

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 108-122 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis a http://www.glycoepitope.jp/epitopes/EP0008

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 824-829 OrganismTaxon denotes human 9606
T2 965-970 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 843-869 Body_part denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL_0002328
T2 879-883 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 984-1010 Body_part denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL_0002328
T4 1020-1024 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 1282-1287 Body_part denotes plate http://purl.obolibrary.org/obo/UBERON_6004475

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 599-608 Body_part denotes proximity http://purl.obolibrary.org/obo/MAT_0000491
T2 879-883 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T3 1020-1024 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 130-133 Phenotype denotes sLe HP:0002725
T2 188-193 Phenotype denotes tumor HP:0002664
T3 486-492 Phenotype denotes cancer HP:0002664
T4 745-748 Phenotype denotes sLe HP:0002725
T5 884-893 Phenotype denotes carcinoma HP:0030731
T6 950-953 Phenotype denotes sLe HP:0002725
T7 1025-1034 Phenotype denotes carcinoma HP:0030731
T8 1447-1453 Phenotype denotes cancer HP:0002664

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 188-199 Cell denotes tumor cells http://purl.obolibrary.org/obo/CL:0001063
T2 843-869 Cell denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL:0002328
T3 984-1010 Cell denotes bronchial epithelial cells http://purl.obolibrary.org/obo/CL:0002328
T4 1447-1459 Cell denotes cancer cells http://purl.obolibrary.org/obo/CL:0001064