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PubMed:25967458 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-67 Sentence denotes EMMPRIN in gynecologic cancers: pathologic and therapeutic aspects.
TextSentencer_T2 68-258 Sentence denotes The highly glycosylated transmembrane protein extracellular matrix metalloproteinase inducer (EMMPRIN) is associated with several pathological conditions, including various types of cancers.
TextSentencer_T3 259-590 Sentence denotes In different gynecological malignancies, such as ovarian, cervical, and endometrial cancers, EMMPRIN plays significant roles in cell adhesion modulation, tumor growth, invasion, angiogenesis, and metastasis by inducing the production of various molecules, including matrix metalloproteinases and vascular endothelial growth factor.
TextSentencer_T4 591-709 Sentence denotes Because of its high level of expression, EMMPRIN can possibly be used as a diagnostic marker of gynecological cancers.
TextSentencer_T5 710-955 Sentence denotes Recent studies have showed that targeting EMMPRIN, especially by RNA interference (RNAi) technology, has promising therapeutic potential in basic research on gynecological cancer treatments, which make a platform for the future clinical success.
TextSentencer_T6 956-1102 Sentence denotes This review study focused on the association of EMMPRIN in gynecological cancers in the perspectives of pathogenesis, diagnosis, and therapeutics.
T1 0-67 Sentence denotes EMMPRIN in gynecologic cancers: pathologic and therapeutic aspects.
T2 68-258 Sentence denotes The highly glycosylated transmembrane protein extracellular matrix metalloproteinase inducer (EMMPRIN) is associated with several pathological conditions, including various types of cancers.
T3 259-590 Sentence denotes In different gynecological malignancies, such as ovarian, cervical, and endometrial cancers, EMMPRIN plays significant roles in cell adhesion modulation, tumor growth, invasion, angiogenesis, and metastasis by inducing the production of various molecules, including matrix metalloproteinases and vascular endothelial growth factor.
T4 591-709 Sentence denotes Because of its high level of expression, EMMPRIN can possibly be used as a diagnostic marker of gynecological cancers.
T5 710-955 Sentence denotes Recent studies have showed that targeting EMMPRIN, especially by RNA interference (RNAi) technology, has promising therapeutic potential in basic research on gynecological cancer treatments, which make a platform for the future clinical success.
T6 956-1102 Sentence denotes This review study focused on the association of EMMPRIN in gynecological cancers in the perspectives of pathogenesis, diagnosis, and therapeutics.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
25967458-2#93#100#gene682 352-359 gene682 denotes EMMPRIN
25967458-2#296#330#gene7422 555-589 gene7422 denotes vascular endothelial growth factor
25967458-2#196#206#diseaseC0027627 455-465 diseaseC0027627 denotes metastasis
93#100#gene682196#206#diseaseC0027627 25967458-2#93#100#gene682 25967458-2#196#206#diseaseC0027627 associated_with EMMPRIN,metastasis
296#330#gene7422196#206#diseaseC0027627 25967458-2#296#330#gene7422 25967458-2#196#206#diseaseC0027627 associated_with vascular endothelial growth factor,metastasis

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T646 352-359 gene:682 denotes EMMPRIN
T647 455-465 disease:C0027627 denotes metastasis
T648 555-589 gene:7422 denotes vascular endothelial growth factor
R1 T646 T647 associated_with EMMPRIN,metastasis
R2 T648 T647 associated_with vascular endothelial growth factor,metastasis