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GoldHamster

Id Subject Object Predicate Lexical cue
T1 0-11 D001932 denotes Brain tumor
T2 0-11 D001932 denotes Brain tumor
T5 17-25 SO:0000001 denotes sequence
T9 35-38 SO:0000356 denotes RNA
T8 35-38 GO:0005562 denotes RNA
T10 35-46 GO:0003723 denotes RNA-binding
T11 35-54 P99148 denotes RNA-binding protein
T12 35-54 Q5SMF6 denotes RNA-binding protein
T13 35-54 Q9ZL64 denotes RNA-binding protein
T14 35-54 Q4UK20 denotes RNA-binding protein
T15 35-54 Q68VV0 denotes RNA-binding protein
T16 35-54 Q8CPC2 denotes RNA-binding protein
T17 35-54 P56958 denotes RNA-binding protein
T18 35-54 P09339 denotes RNA-binding protein
T19 35-54 Q8NQ98 denotes RNA-binding protein
T20 35-54 Q5HPJ0 denotes RNA-binding protein
T21 35-54 P63433 denotes RNA-binding protein
T22 35-54 Q5HG69 denotes RNA-binding protein
T23 35-54 Q9RTN7 denotes RNA-binding protein
T24 35-54 P13278 denotes RNA-binding protein
T25 35-54 Q9I3F5 denotes RNA-binding protein
T26 35-54 P36683 denotes RNA-binding protein
T27 35-54 P28890 denotes RNA-binding protein
T28 35-54 P31612 denotes RNA-binding protein
T29 35-54 O08451 denotes RNA-binding protein
T30 35-54 Q9ZCF4 denotes RNA-binding protein
T31 35-54 Q85442 denotes RNA-binding protein
T32 35-54 Q59938 denotes RNA-binding protein
T33 35-54 Q6GH55 denotes RNA-binding protein
T35 35-54 Q8FTA8 denotes RNA-binding protein
T36 35-54 Q1RKD5 denotes RNA-binding protein
T37 35-54 P63434 denotes RNA-binding protein
T38 35-54 P70920 denotes RNA-binding protein
T39 35-54 Q8ZP52 denotes RNA-binding protein
T40 35-54 Q937N8 denotes RNA-binding protein
T41 35-54 P37032 denotes RNA-binding protein
T42 35-54 P56418 denotes RNA-binding protein
T43 35-54 Q92G90 denotes RNA-binding protein
T44 35-54 Q2A1K3 denotes RNA-binding protein
T45 35-54 A0QX20 denotes RNA-binding protein
T46 35-54 Q9I2V5 denotes RNA-binding protein
T47 35-54 Q8ZRS8 denotes RNA-binding protein
T48 35-54 Q6NH63 denotes RNA-binding protein
T49 35-54 A4PBQ0 denotes RNA-binding protein
T50 35-54 O53166 denotes RNA-binding protein
T51 35-54 P82866 denotes RNA-binding protein
T52 35-54 P25516 denotes RNA-binding protein
T53 35-54 Q4JVM4 denotes RNA-binding protein
T54 35-54 P74582 denotes RNA-binding protein
T55 35-54 Q6G9K9 denotes RNA-binding protein
T34 35-54 D016601 denotes RNA-binding protein
T56 39-46 SO:0100018 denotes binding
T57 39-46 SO:0001091 denotes binding
T64 47-54 SO:0000104 denotes protein
T60 47-54 GO:0003675 denotes protein
T65 68-81 D023121 denotes maternal mRNA
T68 77-81 SO:0000234 denotes mRNA
T69 103-113 2294143 denotes Drosophila
T70 103-113 504603 denotes Drosophila
T71 103-113 2294139 denotes Drosophila
T72 103-113 2294145 denotes Drosophila
T73 103-113 2294141 denotes Drosophila
T74 103-113 2294142 denotes Drosophila
T75 103-113 2294144 denotes Drosophila
T76 103-113 2294140 denotes Drosophila
T77 103-113 D004330 denotes Drosophila
T78 103-113 2080301 denotes Drosophila
T79 134-144 SO:1000009 denotes transition
T80 158-169 D001932 denotes Brain tumor
T81 158-169 D001932 denotes Brain tumor
T84 171-175 PR:Q8MQJ9 denotes BRAT
T85 182-192 2294143 denotes Drosophila
T86 182-192 504603 denotes Drosophila
T87 182-192 2294139 denotes Drosophila
T88 182-192 2294145 denotes Drosophila
T89 182-192 2294141 denotes Drosophila
T90 182-192 2294142 denotes Drosophila
T91 182-192 2294144 denotes Drosophila
T92 182-192 2294140 denotes Drosophila
T93 182-192 D004330 denotes Drosophila
T94 182-192 2080301 denotes Drosophila
T95 207-211 PR:000016620 denotes TRIM
T96 207-211 Q3SYX1 denotes TRIM
T97 207-211 Q6PIZ9 denotes TRIM
T98 207-211 Q3UU67 denotes TRIM
T100 212-215 PR:Q9NZ71 denotes NHL
T101 212-215 PR:000014340 denotes NHL
T99 212-215 D008228 denotes NHL
T106 216-223 SO:0000104 denotes protein
T105 216-223 PR:000000001 denotes protein
T103 216-223 CHEBI:36080 denotes protein
T104 216-223 CHEBI:11122 denotes protein
T102 216-223 GO:0003675 denotes protein
T107 247-256 SO:0000856 denotes conserved
T108 334-338 PR:Q8MQJ9 denotes BRAT
T111 416-419 GO:0005562 denotes RNA
T112 416-419 SO:0000356 denotes RNA
T113 416-427 GO:0003723 denotes RNA-binding
T114 416-435 P99148 denotes RNA-binding protein
T115 416-435 Q5SMF6 denotes RNA-binding protein
T116 416-435 Q9ZL64 denotes RNA-binding protein
T117 416-435 Q4UK20 denotes RNA-binding protein
T118 416-435 Q68VV0 denotes RNA-binding protein
T119 416-435 Q8CPC2 denotes RNA-binding protein
T120 416-435 P56958 denotes RNA-binding protein
T121 416-435 P09339 denotes RNA-binding protein
T122 416-435 Q8NQ98 denotes RNA-binding protein
T123 416-435 Q5HPJ0 denotes RNA-binding protein
T124 416-435 P63433 denotes RNA-binding protein
T125 416-435 Q5HG69 denotes RNA-binding protein
T126 416-435 Q9RTN7 denotes RNA-binding protein
T127 416-435 P13278 denotes RNA-binding protein
T128 416-435 Q9I3F5 denotes RNA-binding protein
T129 416-435 P36683 denotes RNA-binding protein
T130 416-435 P28890 denotes RNA-binding protein
T131 416-435 P31612 denotes RNA-binding protein
T132 416-435 O08451 denotes RNA-binding protein
T133 416-435 Q9ZCF4 denotes RNA-binding protein
T134 416-435 Q85442 denotes RNA-binding protein
T135 416-435 Q59938 denotes RNA-binding protein
T136 416-435 Q6GH55 denotes RNA-binding protein
T138 416-435 Q8FTA8 denotes RNA-binding protein
T139 416-435 Q1RKD5 denotes RNA-binding protein
T140 416-435 P63434 denotes RNA-binding protein
T141 416-435 P70920 denotes RNA-binding protein
T142 416-435 Q8ZP52 denotes RNA-binding protein
T143 416-435 Q937N8 denotes RNA-binding protein
T144 416-435 P37032 denotes RNA-binding protein
T145 416-435 P56418 denotes RNA-binding protein
T146 416-435 Q92G90 denotes RNA-binding protein
T147 416-435 Q2A1K3 denotes RNA-binding protein
T148 416-435 A0QX20 denotes RNA-binding protein
T149 416-435 Q9I2V5 denotes RNA-binding protein
T150 416-435 Q8ZRS8 denotes RNA-binding protein
T151 416-435 Q6NH63 denotes RNA-binding protein
T152 416-435 A4PBQ0 denotes RNA-binding protein
T153 416-435 O53166 denotes RNA-binding protein
T154 416-435 P82866 denotes RNA-binding protein
T155 416-435 P25516 denotes RNA-binding protein
T156 416-435 Q4JVM4 denotes RNA-binding protein
T157 416-435 P74582 denotes RNA-binding protein
T158 416-435 Q6G9K9 denotes RNA-binding protein
T137 416-435 D016601 denotes RNA-binding protein
T159 420-427 SO:0100018 denotes binding
T160 420-427 SO:0001091 denotes binding
T163 428-435 GO:0003675 denotes protein
T167 428-435 SO:0000104 denotes protein
T168 445-448 PR:000001890 denotes PUM
T169 445-448 PR:000013492 denotes PUM
T170 445-448 PR:P25822 denotes PUM
T171 445-448 PR:P15941 denotes PUM
T172 445-448 P15941 denotes PUM
T173 499-503 PR:Q8MQJ9 denotes BRAT
T176 522-525 GO:0005562 denotes RNA
T177 522-525 SO:0000356 denotes RNA
T174 522-525 CHEBI:33697 denotes RNA
T175 522-525 D012313 denotes RNA
T178 539-547 SO:0000001 denotes sequence
T179 562-566 PR:Q8MQJ9 denotes BRAT
T180 582-586 PR:Q8MQJ9 denotes BRAT
T181 596-606 GO:0065007 denotes regulation
T182 631-634 PR:000001890 denotes PUM
T183 631-634 PR:000013492 denotes PUM
T184 631-634 PR:P25822 denotes PUM
T185 631-634 PR:P15941 denotes PUM
T186 631-634 P15941 denotes PUM
T187 639-643 PR:Q8MQJ9 denotes BRAT
T188 668-678 GO:0065007 denotes regulation
T189 683-690 32644 denotes unknown
T190 701-707 SO:0001026 denotes Genome
T191 759-763 PR:Q8MQJ9 denotes BRAT
T192 772-775 PR:000001890 denotes PUM
T193 772-775 PR:000013492 denotes PUM
T194 772-775 PR:P25822 denotes PUM
T195 772-775 PR:P15941 denotes PUM
T196 772-775 P15941 denotes PUM
T197 779-789 2294143 denotes Drosophila
T198 779-789 504603 denotes Drosophila
T199 779-789 2294139 denotes Drosophila
T200 779-789 2294145 denotes Drosophila
T201 779-789 2294141 denotes Drosophila
T202 779-789 2294142 denotes Drosophila
T203 779-789 2294144 denotes Drosophila
T204 779-789 2294140 denotes Drosophila
T205 779-789 D004330 denotes Drosophila
T206 779-789 2080301 denotes Drosophila
T207 831-842 SO:0000068 denotes overlapping
T208 858-862 PR:Q8MQJ9 denotes BRAT
T209 887-895 CHEBI:36080 denotes proteins
T210 989-992 PR:000001890 denotes PUM
T211 989-992 PR:000013492 denotes PUM
T212 989-992 PR:P25822 denotes PUM
T213 989-992 PR:P15941 denotes PUM
T214 989-992 P15941 denotes PUM
T215 1088-1091 CHEBI:33697 denotes RNA
T216 1088-1091 D012313 denotes RNA
T217 1088-1091 GO:0005562 denotes RNA
T219 1088-1097 SO:0000715 denotes RNA motif
T222 1112-1116 PR:Q8MQJ9 denotes BRAT
T223 1130-1134 PR:Q8MQJ9 denotes BRAT
T224 1144-1154 GO:0065007 denotes regulation
T225 1158-1164 UBERON:0000479 denotes tissue
T226 1205-1209 PR:Q8MQJ9 denotes BRAT
T227 1257-1261 PR:Q8MQJ9 denotes BRAT
T228 1286-1296 GO:0065007 denotes regulation
T229 1321-1333 32644 denotes unidentified
T230 1342-1352 SO:0000673 denotes transcript
T231 1353-1364 GO:0009056 denotes degradation
T232 1420-1424 PR:Q8MQJ9 denotes BRAT
T233 1535-1545 SO:1000009 denotes transition
T234 1592-1598 SO:0001026 denotes genome
T235 1644-1648 PR:000016620 denotes TRIM
T236 1644-1648 Q3SYX1 denotes TRIM
T237 1644-1648 Q6PIZ9 denotes TRIM
T238 1644-1648 Q3UU67 denotes TRIM
T240 1649-1652 PR:Q9NZ71 denotes NHL
T241 1649-1652 PR:000014340 denotes NHL
T239 1649-1652 D008228 denotes NHL
T245 1653-1660 PR:000000001 denotes protein
T242 1653-1660 GO:0003675 denotes protein
T243 1653-1660 CHEBI:36080 denotes protein
T244 1653-1660 CHEBI:11122 denotes protein
T246 1653-1660 SO:0000104 denotes protein
T249 1696-1699 GO:0005562 denotes RNA
T247 1696-1699 CHEBI:33697 denotes RNA
T248 1696-1699 D012313 denotes RNA
T251 1696-1705 SO:0000715 denotes RNA motif
T257 1720-1727 PR:000000001 denotes protein
T254 1720-1727 GO:0003675 denotes protein
T255 1720-1727 CHEBI:36080 denotes protein
T256 1720-1727 CHEBI:11122 denotes protein
T258 1720-1727 SO:0000104 denotes protein
T259 1736-1740 PR:Q8MQJ9 denotes BRAT
T260 1761-1786 Q9CJ45 denotes transcriptional regulator
T261 1794-1806 UBERON:0019248 denotes early embryo
T263 1858-1861 PR:000001890 denotes PUM
T264 1858-1861 PR:000013492 denotes PUM
T265 1858-1861 PR:P25822 denotes PUM
T266 1858-1861 PR:P15941 denotes PUM
T267 1858-1861 P15941 denotes PUM

PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T1 158-691 BACKGROUND denotes Brain tumor (BRAT) is a Drosophila member of the TRIM-NHL protein family. This family is conserved among metazoans and its members function as post-transcriptional regulators. BRAT was thought to be recruited to mRNAs indirectly through interaction with the RNA-binding protein Pumilio (PUM). However, it has recently been demonstrated that BRAT directly binds to RNA. The precise sequence recognized by BRAT, the extent of BRAT-mediated regulation, and the exact roles of PUM and BRAT in post-transcriptional regulation are unknown.
T2 701-1546 RESULTS denotes Genome-wide identification of transcripts associated with BRAT or with PUM in Drosophila embryos shows that they bind largely non-overlapping sets of mRNAs. BRAT binds mRNAs that encode proteins associated with a variety of functions, many of which are distinct from those implemented by PUM-associated transcripts. Computational analysis of in vitro and in vivo data identified a novel RNA motif recognized by BRAT that confers BRAT-mediated regulation in tissue culture cells. The regulatory status of BRAT-associated mRNAs suggests a prominent role for BRAT in post-transcriptional regulation, including a previously unidentified role in transcript degradation. Transcriptomic analysis of embryos lacking functional BRAT reveals an important role in mediating the decay of hundreds of maternal mRNAs during the maternal-to-zygotic transition.
T3 1560-1862 CONCLUSIONS denotes Our results represent the first genome-wide analysis of the mRNAs associated with a TRIM-NHL protein and the first identification of an RNA motif bound by this protein family. BRAT is a prominent post-transcriptional regulator in the early embryo through mechanisms that are largely independent of PUM.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 15-16 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T2 180-181 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T3 463-466 CVCL_6758|Undefined_cell_line_type|Cricetulus griseus denotes has
T4 463-466 CVCL_E689|Transformed_cell_line|Homo sapiens denotes has
T5 843-847 CVCL_WY71|Spontaneously_immortalized_cell_line|Oncorhynchus keta denotes sets
T6 912-913 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T7 1080-1081 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T8 1236-1237 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T9 1308-1309 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T10 1433-1435 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T11 1433-1435 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T12 1642-1643 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T13 1693-1695 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T14 1693-1695 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T15 1744-1745 CVCL_6479|Finite_cell_line|Mus musculus denotes a