PubMed:25946186 / 1114-1385 JSONTXT

{"project":"LitCoin-sentences","denotations":[{"id":"T11","span":{"begin":0,"end":271},"obj":"Sentence"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-entities","denotations":[{"id":"10625","span":{"begin":16,"end":21},"obj":"GeneOrGeneProduct"},{"id":"10626","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"10627","span":{"begin":104,"end":113},"obj":"GeneOrGeneProduct"},{"id":"10628","span":{"begin":115,"end":124},"obj":"GeneOrGeneProduct"},{"id":"10629","span":{"begin":126,"end":131},"obj":"GeneOrGeneProduct"},{"id":"10630","span":{"begin":136,"end":139},"obj":"GeneOrGeneProduct"},{"id":"10631","span":{"begin":165,"end":168},"obj":"GeneOrGeneProduct"},{"id":"10632","span":{"begin":173,"end":176},"obj":"GeneOrGeneProduct"},{"id":"10633","span":{"begin":203,"end":208},"obj":"GeneOrGeneProduct"},{"id":"10634","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A36","pred":"db_id","subj":"10625","obj":"NCBIGene:79626"},{"id":"A37","pred":"db_id","subj":"10626","obj":"MESH:D008175"},{"id":"A38","pred":"db_id","subj":"10627","obj":"NCBIGene:836"},{"id":"A39","pred":"db_id","subj":"10628","obj":"NCBIGene:842"},{"id":"A40","pred":"db_id","subj":"10629","obj":"NCBIGene:596"},{"id":"A41","pred":"db_id","subj":"10630","obj":"NCBIGene:581"},{"id":"A42","pred":"db_id","subj":"10631","obj":"NCBIGene:1432"},{"id":"A43","pred":"db_id","subj":"10632","obj":"NCBIGene:207"},{"id":"A44","pred":"db_id","subj":"10633","obj":"NCBIGene:79626"},{"id":"A45","pred":"db_id","subj":"10634","obj":"MESH:D008175"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin_Mondo","denotations":[{"id":"T15","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T16","span":{"begin":36,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T17","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T18","span":{"begin":242,"end":248},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A15","pred":"mondo_id","subj":"T15","obj":"0008903"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"0004992"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"0008903"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"0004992"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T27","span":{"begin":16,"end":21},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":43,"end":47},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":48,"end":57},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":76,"end":85},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":104,"end":113},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":115,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":126,"end":131},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":203,"end":208},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":220,"end":225},"obj":"GeneOrGeneProduct"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T45","span":{"begin":16,"end":21},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":31,"end":35},"obj":"GeneOrGeneProduct"},{"id":"T47","span":{"begin":43,"end":47},"obj":"GeneOrGeneProduct"},{"id":"T48","span":{"begin":48,"end":57},"obj":"GeneOrGeneProduct"},{"id":"T49","span":{"begin":76,"end":85},"obj":"GeneOrGeneProduct"},{"id":"T50","span":{"begin":104,"end":113},"obj":"GeneOrGeneProduct"},{"id":"T51","span":{"begin":115,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T52","span":{"begin":126,"end":131},"obj":"GeneOrGeneProduct"},{"id":"T53","span":{"begin":154,"end":164},"obj":"GeneOrGeneProduct"},{"id":"T54","span":{"begin":203,"end":208},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":220,"end":225},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":237,"end":241},"obj":"GeneOrGeneProduct"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T14","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A14","pred":"originalLabel","subj":"T14","obj":"D008175"},{"id":"A15","pred":"originalLabel","subj":"T15","obj":"D008175"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T15","span":{"begin":16,"end":21},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":104,"end":113},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":115,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":126,"end":131},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":173,"end":176},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":203,"end":208},"obj":"GeneOrGeneProduct"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin_Mondo_095","denotations":[{"id":"T13","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"0008903"},{"id":"A14","pred":"mondo_id","subj":"T13","obj":"0005138"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"0008903"},{"id":"A16","pred":"mondo_id","subj":"T15","obj":"0005138"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T16","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T17","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A16","pred":"ID:","subj":"T16","obj":"D008175"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D008175"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T15","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T16","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A15","pred":"#label","subj":"T15","obj":"D008175"},{"id":"A16","pred":"#label","subj":"T16","obj":"D008175"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T20","span":{"begin":203,"end":208},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":173,"end":176},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":126,"end":131},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":115,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":104,"end":113},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":16,"end":21},"obj":"GeneOrGeneProduct"},{"id":"T23143","span":{"begin":237,"end":248},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T77133","span":{"begin":31,"end":42},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A16","pred":"#label","subj":"T23143","obj":"D008175"},{"id":"A15","pred":"#label","subj":"T77133","obj":"D008175"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}

{"project":"PubmedHPO","denotations":[{"id":"T18","span":{"begin":31,"end":42},"obj":"HP_0100526"},{"id":"T19","span":{"begin":36,"end":42},"obj":"HP_0002664"},{"id":"T20","span":{"begin":237,"end":248},"obj":"HP_0100526"},{"id":"T21","span":{"begin":242,"end":248},"obj":"HP_0002664"}],"text":"Taken together, TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3, caspase-9, Bcl-2 and Bax, possibly via regulating P38 and Akt pathways, indicating that TIPE2 might be a novel marker for lung cancer diagnosis and therapy."}