> top > docs > PubMed:25881090 > annotations

PubMed:25881090 JSONTXT

Annnotations TAB JSON ListView MergeView

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-204 Sentence denotes Positive regulatory effects of perioperative probiotic treatment on postoperative liver complications after colorectal liver metastases surgery: a double-center and double-blind randomized clinical trial.
T2 205-216 Sentence denotes BACKGROUND:
T3 217-332 Sentence denotes Colorectal liver metastases (CLM) occur frequently and postoperative intestinal infection is a common complication.
T4 333-465 Sentence denotes Our previous study showed that probiotics could decrease the rate of infectious complications after colectomy for colorectal cancer.
T5 466-699 Sentence denotes To determine the effects of the perioperative administration of probiotics on serum zonulin levels which is a marker of intestinal permeability and the subsequent impact on postoperative infectious complications in patients with CLM.
T6 700-708 Sentence denotes METHODS:
T7 709-811 Sentence denotes 150 patients with CLM were randomly divided into control group (n = 68) and probiotics group (n = 66).
T8 812-958 Sentence denotes Probiotics and placebo were given orally for 6 days preoperatively and 10 days postoperatively to control group and probiotics group respectively.
T9 959-1058 Sentence denotes We used the local resection for metastatic tumor ,while for large tumor, the segmental hepatectomy.
T10 1059-1095 Sentence denotes Postoperative outcome were recorded.
T11 1096-1281 Sentence denotes Furthermore, complications in patients with normal intestinal barrier function and the relation with serum zonulin were analyzed to evaluate the impact on the liver barrier dysfunction.
T12 1282-1290 Sentence denotes RESULTS:
T13 1291-1386 Sentence denotes The incidence of infectious complications in the probiotics group was lower than control group.
T14 1387-1506 Sentence denotes Analysis of CLM patients with normal postoperative intestinal barrier function paralleled with the serum zonulin level.
T15 1507-1620 Sentence denotes And probiotics could also reduce the concentration of serum zonulin (P = 0.004) and plasma endotoxin (P < 0.001).
T16 1621-1632 Sentence denotes CONCLUSION:
T17 1633-1917 Sentence denotes Perioperative probiotics treatment could reduce the serum zonulin level, the rate of postoperative septicemia and maintain the liver barrier in patients undergoing CLM surgery. we propose a new model about the regulation of probiotics to liver barrier via clinical regulatory pathway.
T18 1918-2069 Sentence denotes We recommend the preoperative oral intake of probiotics combined with postoperative continued probiotics treatment in patients who undergo CLM surgery.
T19 2070-2089 Sentence denotes TRIAL REGISTRATION:
T20 2090-2112 Sentence denotes ChiCTR-TRC- 12002841 .
T21 2113-2124 Sentence denotes 2012/12/21.
T1 0-204 Sentence denotes Positive regulatory effects of perioperative probiotic treatment on postoperative liver complications after colorectal liver metastases surgery: a double-center and double-blind randomized clinical trial.
T2 205-216 Sentence denotes BACKGROUND:
T3 217-332 Sentence denotes Colorectal liver metastases (CLM) occur frequently and postoperative intestinal infection is a common complication.
T4 333-465 Sentence denotes Our previous study showed that probiotics could decrease the rate of infectious complications after colectomy for colorectal cancer.
T5 466-699 Sentence denotes To determine the effects of the perioperative administration of probiotics on serum zonulin levels which is a marker of intestinal permeability and the subsequent impact on postoperative infectious complications in patients with CLM.
T6 700-708 Sentence denotes METHODS:
T7 709-811 Sentence denotes 150 patients with CLM were randomly divided into control group (n = 68) and probiotics group (n = 66).
T8 812-958 Sentence denotes Probiotics and placebo were given orally for 6 days preoperatively and 10 days postoperatively to control group and probiotics group respectively.
T9 959-1058 Sentence denotes We used the local resection for metastatic tumor ,while for large tumor, the segmental hepatectomy.
T10 1059-1095 Sentence denotes Postoperative outcome were recorded.
T11 1096-1281 Sentence denotes Furthermore, complications in patients with normal intestinal barrier function and the relation with serum zonulin were analyzed to evaluate the impact on the liver barrier dysfunction.
T12 1282-1290 Sentence denotes RESULTS:
T13 1291-1386 Sentence denotes The incidence of infectious complications in the probiotics group was lower than control group.
T14 1387-1506 Sentence denotes Analysis of CLM patients with normal postoperative intestinal barrier function paralleled with the serum zonulin level.
T15 1507-1620 Sentence denotes And probiotics could also reduce the concentration of serum zonulin (P = 0.004) and plasma endotoxin (P < 0.001).
T16 1621-1632 Sentence denotes CONCLUSION:
T17 1633-1917 Sentence denotes Perioperative probiotics treatment could reduce the serum zonulin level, the rate of postoperative septicemia and maintain the liver barrier in patients undergoing CLM surgery. we propose a new model about the regulation of probiotics to liver barrier via clinical regulatory pathway.
T18 1918-2069 Sentence denotes We recommend the preoperative oral intake of probiotics combined with postoperative continued probiotics treatment in patients who undergo CLM surgery.
T19 2070-2089 Sentence denotes TRIAL REGISTRATION:
T20 2090-2112 Sentence denotes ChiCTR-TRC- 12002841 .
T21 2113-2124 Sentence denotes 2012/12/21.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 458-464 HP_0002664 denotes cancer

yaoziqian_800_3

Id Subject Object Predicate Lexical cue
T1 45-54 CI denotes probiotic
T10 1399-1402 DP denotes CLM
T11 695-698 DP denotes CLM
T12 246-249 DP denotes CLM
T13 217-244 DP denotes Colorectal liver metastases
T14 727-730 DP denotes CLM
T15 1647-1657 CI denotes probiotics
T16 1797-1800 DP denotes CLM
T17 1857-1867 CI denotes probiotics
T18 1963-1973 CI denotes probiotics
T2 108-135 DP denotes colorectal liver metastases
T20 2057-2060 DP denotes CLM
T21 812-822 CI denotes Probiotics
T3 364-374 CI denotes probiotics
T4 530-540 CI denotes probiotics
T5 785-795 CI denotes probiotics
T7 827-834 CI denotes placebo
T8 928-938 CI denotes probiotics
T9 1340-1350 CI denotes probiotics
T22 2012-2022 CI denotes probiotics
T23 1511-1521 CI denotes probiotics

Zierdiyeerkenaili_800_3

Id Subject Object Predicate Lexical cue
T1 812-822 CI denotes Probiotics
T10 1963-1973 CI denotes probiotics
T11 2012-2022 CI denotes probiotics
T12 45-54 CI denotes probiotic
T16 217-244 DP denotes Colorectal liver metastases
T17 246-249 DP denotes CLM
T18 695-698 DP denotes CLM
T19 727-730 DP denotes CLM
T2 785-795 CI denotes probiotics
T20 1399-1402 DP denotes CLM
T21 1797-1800 DP denotes CLM
T22 2057-2060 DP denotes CLM
T23 827-834 CI denotes placebo
T25 108-135 DP denotes colorectal liver metastases
T3 364-374 CI denotes probiotics
T4 530-540 CI denotes probiotics
T5 928-938 CI denotes probiotics
T6 1340-1350 CI denotes probiotics
T7 1511-1521 CI denotes probiotics
T8 1647-1657 CI denotes probiotics
T9 1857-1867 CI denotes probiotics