PubMed:2585399 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PubMed/sourceid/2585399","sourcedb":"PubMed","sourceid":"2585399","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/2585399","text":"Lack of association of HLA-DR4 with interleukin 1 beta secretion from peripheral blood monocytes in patients with rheumatoid arthritis.\nThe possible association between HLA-DR4 and interleukin 1 beta (IL-1 beta) secretion from peripheral blood monocytes was analyzed using 34 female patients, with definite rheumatoid arthritis (RA). RA monocytes in serum-free medium or medium supplemented with 10% fetal calf serum secreted IL-1 spontaneously. The level of secretion was enhanced by stimulation with pyrogen-free type II collagen as determined by comparison with 30 healthy individuals matched for age and sex. No association between HLA-DR4 and spontaneous or stimulated IL-1 release from RA monocytes was observed.","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":307,"end":327},"obj":"HP_0001370"},{"id":"T2","span":{"begin":318,"end":327},"obj":"HP_0001369"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#e4ec93","default":true}]}]}}