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PubMed:25840968 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 1179-1185 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1179-1185 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-127 Sentence denotes Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates.
TextSentencer_T2 128-269 Sentence denotes Legionaminic acids (Leg) are bacterial analogs of neuraminic acid, with the same stereochemistry but different substituents at C5, C7 and C9.
TextSentencer_T3 270-575 Sentence denotes Hence they may be incorporated into useful analogs of sialoglycoconjugates, and we previously reported two sialyltransferases that could utilize cytidine monophosphate (CMP)-Leg5Ac7Ac for preparation of Leg glycoconjugates, which were resistant to sialidases [Watson DC, Leclerc S, Wakarchuk WW, Young NM.
TextSentencer_T4 576-581 Sentence denotes 2011.
TextSentencer_T5 582-696 Sentence denotes Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid.
TextSentencer_T6 697-710 Sentence denotes Glycobiology.
TextSentencer_T7 711-723 Sentence denotes 21:99-108.].
TextSentencer_T8 724-800 Sentence denotes These were the porcine ST3Gal1 and Pasteurella multocida sialyltransferases.
TextSentencer_T9 801-910 Sentence denotes We now report two additional sialyltransferases with superior Leg-transferase properties to the previous two.
TextSentencer_T10 911-1216 Sentence denotes These are (i) a truncated form of a Photobacterium α2,6-sialyltransferase with an Ala-Met mutation in its active site, and (ii) an α2,3-sialyltransferase from Neisseria meningitidis MC58 with a higher transferase activity than the P. multocida enzyme, with either CMP-Neu5Ac or CMP-Leg5Ac7Ac as the donor.
TextSentencer_T11 1217-1372 Sentence denotes These enzymes will enable the production of useful Leg5Ac7Ac glycoconjugate derivatives with either α2,6 or α2,3 linkages and unique biological properties.
T1 0-127 Sentence denotes Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates.
T2 128-269 Sentence denotes Legionaminic acids (Leg) are bacterial analogs of neuraminic acid, with the same stereochemistry but different substituents at C5, C7 and C9.
T3 270-575 Sentence denotes Hence they may be incorporated into useful analogs of sialoglycoconjugates, and we previously reported two sialyltransferases that could utilize cytidine monophosphate (CMP)-Leg5Ac7Ac for preparation of Leg glycoconjugates, which were resistant to sialidases [Watson DC, Leclerc S, Wakarchuk WW, Young NM.
T4 576-581 Sentence denotes 2011.
T5 582-696 Sentence denotes Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid.
T6 697-723 Sentence denotes Glycobiology. 21:99-108.].
T7 724-800 Sentence denotes These were the porcine ST3Gal1 and Pasteurella multocida sialyltransferases.
T8 801-910 Sentence denotes We now report two additional sialyltransferases with superior Leg-transferase properties to the previous two.
T9 911-1216 Sentence denotes These are (i) a truncated form of a Photobacterium α2,6-sialyltransferase with an Ala-Met mutation in its active site, and (ii) an α2,3-sialyltransferase from Neisseria meningitidis MC58 with a higher transferase activity than the P. multocida enzyme, with either CMP-Neu5Ac or CMP-Leg5Ac7Ac as the donor.
T10 1217-1372 Sentence denotes These enzymes will enable the production of useful Leg5Ac7Ac glycoconjugate derivatives with either α2,6 or α2,3 linkages and unique biological properties.
T1 0-127 Sentence denotes Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates.
T2 128-269 Sentence denotes Legionaminic acids (Leg) are bacterial analogs of neuraminic acid, with the same stereochemistry but different substituents at C5, C7 and C9.
T3 270-575 Sentence denotes Hence they may be incorporated into useful analogs of sialoglycoconjugates, and we previously reported two sialyltransferases that could utilize cytidine monophosphate (CMP)-Leg5Ac7Ac for preparation of Leg glycoconjugates, which were resistant to sialidases [Watson DC, Leclerc S, Wakarchuk WW, Young NM.
T4 576-581 Sentence denotes 2011.
T5 582-696 Sentence denotes Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid.
T6 697-710 Sentence denotes Glycobiology.
T7 711-723 Sentence denotes 21:99-108.].
T8 724-800 Sentence denotes These were the porcine ST3Gal1 and Pasteurella multocida sialyltransferases.
T9 801-910 Sentence denotes We now report two additional sialyltransferases with superior Leg-transferase properties to the previous two.
T10 911-1216 Sentence denotes These are (i) a truncated form of a Photobacterium α2,6-sialyltransferase with an Ala-Met mutation in its active site, and (ii) an α2,3-sialyltransferase from Neisseria meningitidis MC58 with a higher transferase activity than the P. multocida enzyme, with either CMP-Neu5Ac or CMP-Leg5Ac7Ac as the donor.
T11 1217-1372 Sentence denotes These enzymes will enable the production of useful Leg5Ac7Ac glycoconjugate derivatives with either α2,6 or α2,3 linkages and unique biological properties.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1179-1185 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac

GlycoBiology-GDGDB

Id Subject Object Predicate Lexical cue
_T1 572-574 http://acgg.asia/db/diseases/gdgdb?con_ui=CON00386 denotes NM

GlycoBiology-PACDB

Id Subject Object Predicate Lexical cue
_T1 1070-1092 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC453,LEC742 denotes Neisseria meningitidis

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 148-151 FMAID:117599 denotes Leg
_T2 148-151 FMAID:24979 denotes Leg
_T3 255-257 FMAID:167723 denotes C5
_T4 255-257 FMAID:63498 denotes C5
_T5 259-261 FMAID:167725 denotes C7
_T6 259-261 FMAID:63500 denotes C7
_T7 473-476 FMAID:24979 denotes Leg
_T8 473-476 FMAID:117599 denotes Leg
_T9 477-492 FMAID:196776 denotes glycoconjugates
_T10 477-492 FMAID:82782 denotes glycoconjugates
_T11 620-635 FMAID:82782 denotes glycoconjugates
_T12 620-635 FMAID:196776 denotes glycoconjugates
_T13 854-862 FMAID:174814 denotes superior
_T14 854-862 FMAID:30337 denotes superior
_T15 854-862 FMAID:274208 denotes superior
_T16 863-866 FMAID:117599 denotes Leg
_T17 863-866 FMAID:24979 denotes Leg
_T18 1278-1292 FMAID:196776 denotes glycoconjugate
_T19 1278-1292 FMAID:82782 denotes glycoconjugate

uniprot-human

Id Subject Object Predicate Lexical cue
T1 51-62 http://www.uniprot.org/uniprot/Q99484 denotes transferase
T2 867-878 http://www.uniprot.org/uniprot/Q99484 denotes transferase
T3 1112-1123 http://www.uniprot.org/uniprot/Q99484 denotes transferase
T4 255-257 http://www.uniprot.org/uniprot/P01031 denotes C5
T5 259-261 http://www.uniprot.org/uniprot/P10643 denotes C7
T6 266-268 http://www.uniprot.org/uniprot/P02748 denotes C9
T7 439-442 http://www.uniprot.org/uniprot/P21941 denotes CMP
T8 1175-1178 http://www.uniprot.org/uniprot/P21941 denotes CMP
T9 1189-1192 http://www.uniprot.org/uniprot/P21941 denotes CMP
T10 1035-1037 http://www.uniprot.org/uniprot/Q8SNA0 denotes ii

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 51-62 http://www.uniprot.org/uniprot/P38649 denotes transferase
T2 867-878 http://www.uniprot.org/uniprot/P38649 denotes transferase
T3 1112-1123 http://www.uniprot.org/uniprot/P38649 denotes transferase
T4 255-257 http://www.uniprot.org/uniprot/P06684 denotes C5
T5 259-261 http://www.uniprot.org/uniprot/P17515 denotes C7
T6 259-261 http://www.uniprot.org/uniprot/Q4KMM3 denotes C7
T7 266-268 http://www.uniprot.org/uniprot/P06683 denotes C9
T8 1035-1037 http://www.uniprot.org/uniprot/P04441 denotes ii

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 759-770 http://purl.bioontology.org/ontology/NCBITAXON/712 denotes Pasteurella
T2 759-770 http://purl.bioontology.org/ontology/NCBITAXON/745 denotes Pasteurella
T3 947-961 http://purl.bioontology.org/ontology/NCBITAXON/661 denotes Photobacterium
T4 947-961 http://purl.bioontology.org/ontology/NCBITAXON/74109 denotes Photobacterium
T5 947-961 http://purl.bioontology.org/ontology/NCBITAXON/81447 denotes Photobacterium
T6 947-961 http://purl.bioontology.org/ontology/NCBITAXON/122277 denotes Photobacterium
T7 947-961 http://purl.bioontology.org/ontology/NCBITAXON/657 denotes Photobacterium
T8 947-963 http://purl.bioontology.org/ontology/NCBITAXON/660 denotes Photobacterium α
T9 947-964 http://purl.bioontology.org/ontology/NCBITAXON/265903 denotes Photobacterium α2
T10 947-964 http://purl.bioontology.org/ontology/NCBITAXON/271856 denotes Photobacterium α2
T11 947-964 http://purl.bioontology.org/ontology/NCBITAXON/747371 denotes Photobacterium α2
T12 947-964 http://purl.bioontology.org/ontology/NCBITAXON/459729 denotes Photobacterium α2
T13 1070-1079 http://purl.bioontology.org/ontology/NCBITAXON/206351 denotes Neisseria
T14 1070-1079 http://purl.bioontology.org/ontology/NCBITAXON/481 denotes Neisseria
T15 1070-1079 http://purl.bioontology.org/ontology/NCBITAXON/482 denotes Neisseria
T16 1070-1092 http://purl.bioontology.org/ontology/NCBITAXON/487 denotes Neisseria meningitidis

GO-BP

Id Subject Object Predicate Lexical cue
T1 51-71 http://purl.obolibrary.org/obo/GO_0004380 denotes transferase activity
T2 1112-1132 http://purl.obolibrary.org/obo/GO_0004380 denotes transferase activity
T3 51-71 http://purl.obolibrary.org/obo/GO_0016740 denotes transferase activity
T4 1112-1132 http://purl.obolibrary.org/obo/GO_0016740 denotes transferase activity
T5 51-71 http://purl.obolibrary.org/obo/GO_0051347 denotes transferase activity
T6 1112-1132 http://purl.obolibrary.org/obo/GO_0051347 denotes transferase activity
T7 592-601 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 148-151 http://purl.obolibrary.org/obo/UBERON_0000978 denotes Leg
T2 473-476 http://purl.obolibrary.org/obo/UBERON_0000978 denotes Leg
T3 863-866 http://purl.obolibrary.org/obo/UBERON_0000978 denotes Leg

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 1001-1009 http://edamontology.org/topic_0199 denotes mutation
T2 1330-1338 http://edamontology.org/topic_0102 denotes linkages

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 364-372 http://edamontology.org/data_2048 denotes reported
T2 808-814 http://edamontology.org/data_2048 denotes report

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 148-151 "http://rdf.glycoinfo.org/glycan/G77742VT" denotes Leg
GlycanIUPAC_T2 473-476 "http://rdf.glycoinfo.org/glycan/G77742VT" denotes Leg
GlycanIUPAC_T3 863-866 "http://rdf.glycoinfo.org/glycan/G77742VT" denotes Leg
GlycanIUPAC_T4 148-151 "http://rdf.glycoinfo.org/glycan/G37836UN" denotes Leg
GlycanIUPAC_T5 473-476 "http://rdf.glycoinfo.org/glycan/G37836UN" denotes Leg
GlycanIUPAC_T6 863-866 "http://rdf.glycoinfo.org/glycan/G37836UN" denotes Leg
GlycanIUPAC_T7 148-151 "http://rdf.glycoinfo.org/glycan/G79899FC" denotes Leg
GlycanIUPAC_T8 473-476 "http://rdf.glycoinfo.org/glycan/G79899FC" denotes Leg
GlycanIUPAC_T9 863-866 "http://rdf.glycoinfo.org/glycan/G79899FC" denotes Leg
GlycanIUPAC_T10 1179-1185 "http://rdf.glycoinfo.org/glycan/G76685HR" denotes Neu5Ac
GlycanIUPAC_T11 1179-1185 "http://rdf.glycoinfo.org/glycan/G65881BF" denotes Neu5Ac
GlycanIUPAC_T12 1179-1185 "http://rdf.glycoinfo.org/glycan/G82702MH" denotes Neu5Ac
GlycanIUPAC_T13 1179-1185 "http://rdf.glycoinfo.org/glycan/G51494MY" denotes Neu5Ac
GlycanIUPAC_T14 1179-1185 "http://rdf.glycoinfo.org/glycan/G37109XL" denotes Neu5Ac
GlycanIUPAC_T15 1179-1185 "http://rdf.glycoinfo.org/glycan/G47427MX" denotes Neu5Ac
GlycanIUPAC_T16 1179-1185 "http://rdf.glycoinfo.org/glycan/G89927NS" denotes Neu5Ac

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 148-151 http://purl.obolibrary.org/obo/UBERON_0000978 denotes Leg
PD-UBERON-AE-B_T2 473-476 http://purl.obolibrary.org/obo/UBERON_0000978 denotes Leg
PD-UBERON-AE-B_T3 863-866 http://purl.obolibrary.org/obo/UBERON_0000978 denotes Leg

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1179-1185 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1179-1185 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 759-780 Organism denotes Pasteurella multocida 747
T2 947-961 Organism denotes Photobacterium 657
T3 1070-1092 Organism denotes Neisseria meningitidis 487

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-127 Sentence denotes Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates.
T2 128-269 Sentence denotes Legionaminic acids (Leg) are bacterial analogs of neuraminic acid, with the same stereochemistry but different substituents at C5, C7 and C9.
T3 270-575 Sentence denotes Hence they may be incorporated into useful analogs of sialoglycoconjugates, and we previously reported two sialyltransferases that could utilize cytidine monophosphate (CMP)-Leg5Ac7Ac for preparation of Leg glycoconjugates, which were resistant to sialidases [Watson DC, Leclerc S, Wakarchuk WW, Young NM.
T4 576-581 Sentence denotes 2011.
T5 582-696 Sentence denotes Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid.
T6 697-723 Sentence denotes Glycobiology. 21:99-108.].
T7 724-800 Sentence denotes These were the porcine ST3Gal1 and Pasteurella multocida sialyltransferases.
T8 801-910 Sentence denotes We now report two additional sialyltransferases with superior Leg-transferase properties to the previous two.
T9 911-1216 Sentence denotes These are (i) a truncated form of a Photobacterium α2,6-sialyltransferase with an Ala-Met mutation in its active site, and (ii) an α2,3-sialyltransferase from Neisseria meningitidis MC58 with a higher transferase activity than the P. multocida enzyme, with either CMP-Neu5Ac or CMP-Leg5Ac7Ac as the donor.
T10 1217-1372 Sentence denotes These enzymes will enable the production of useful Leg5Ac7Ac glycoconjugate derivatives with either α2,6 or α2,3 linkages and unique biological properties.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 148-151 Body_part denotes Leg FMA:24979
T2 473-476 Body_part denotes Leg FMA:24979
T3 863-866 Body_part denotes Leg FMA:24979

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 759-780 OrganismTaxon denotes Pasteurella multocida 747
T2 947-961 OrganismTaxon denotes Photobacterium 657
T3 1070-1092 OrganismTaxon denotes Neisseria meningitidis 487