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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-171 Sentence denotes [Effect of Sanhuang Yilong Decoction combined MTX on the expression of serum IL-1, IL-6, and IL-17 in rheumatoid arthritis patients of accumulated dampness-heat syndrome].
T2 172-182 Sentence denotes OBJECTIVE:
T3 183-471 Sentence denotes To study the effect of bitter-cold herbs easing dampness method (BCHEDM) plus Sanhuang Yilong Decoction (SYD) combined with methotrexate (MTX) on expression levels of interleukin-1 (IL-1), IL-6, and IL-17 in rheumatoid arthritis (RA) patients of accumulated dampness-heat syndrome (ADHS).
T4 472-480 Sentence denotes METHODS:
T5 481-660 Sentence denotes From January 2011 to January 2013 recruited were 90 RA inpatients of ADHS at Department of Integrative Medicine on Rheumatoid Disease, General Hospital of Chengdu Military Region.
T6 661-814 Sentence denotes They were assigned to the treatment group (45 cases) and the control group (45 cases) according to the random digit table produced by SPSS 11.5 Software.
T7 815-974 Sentence denotes Patients in the treatment group were treated by heavy bitter-cold herbs plus SYD combined with MTX, while those in the control group were treated by MTX alone.
T8 975-1138 Sentence denotes Expressional levels of IL-1, IL-6, and IL-17 in serum were detected by enzyme linked immunosorbent assay (ELISA) before treatment, at week 2 and 4 after treatment.
T9 1139-1273 Sentence denotes Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and disease activity score in 28 joints (DAS28) were detected as well.
T10 1274-1282 Sentence denotes RESULTS:
T11 1283-1454 Sentence denotes After two or four weeks of treatment, ESR, CRP, and DAS28 decreased more in the treatment group than in the control group with statistical difference (P < 0.05, P < 0.01).
T12 1455-1684 Sentence denotes After four weeks of treatment, IL-1, IL-6, IL-17, ESR, CRP, and DAS28 in the treatment group were all lower than before treatment and those of the control group at corresponding time points with statistical difference (P < 0.01).
T13 1685-1851 Sentence denotes CONCLUSION: SYD combined MTX could play roles of improving inflammatory indices within 2 weeks, and inhibiting the expression of IL-1, IL-6, and IL-17 within 4 weeks.
T1 0-171 Sentence denotes [Effect of Sanhuang Yilong Decoction combined MTX on the expression of serum IL-1, IL-6, and IL-17 in rheumatoid arthritis patients of accumulated dampness-heat syndrome].
T2 172-182 Sentence denotes OBJECTIVE:
T3 183-471 Sentence denotes To study the effect of bitter-cold herbs easing dampness method (BCHEDM) plus Sanhuang Yilong Decoction (SYD) combined with methotrexate (MTX) on expression levels of interleukin-1 (IL-1), IL-6, and IL-17 in rheumatoid arthritis (RA) patients of accumulated dampness-heat syndrome (ADHS).
T4 472-480 Sentence denotes METHODS:
T5 481-660 Sentence denotes From January 2011 to January 2013 recruited were 90 RA inpatients of ADHS at Department of Integrative Medicine on Rheumatoid Disease, General Hospital of Chengdu Military Region.
T6 661-814 Sentence denotes They were assigned to the treatment group (45 cases) and the control group (45 cases) according to the random digit table produced by SPSS 11.5 Software.
T7 815-974 Sentence denotes Patients in the treatment group were treated by heavy bitter-cold herbs plus SYD combined with MTX, while those in the control group were treated by MTX alone.
T8 975-1138 Sentence denotes Expressional levels of IL-1, IL-6, and IL-17 in serum were detected by enzyme linked immunosorbent assay (ELISA) before treatment, at week 2 and 4 after treatment.
T9 1139-1273 Sentence denotes Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and disease activity score in 28 joints (DAS28) were detected as well.
T10 1274-1282 Sentence denotes RESULTS:
T11 1283-1454 Sentence denotes After two or four weeks of treatment, ESR, CRP, and DAS28 decreased more in the treatment group than in the control group with statistical difference (P < 0.05, P < 0.01).
T12 1455-1684 Sentence denotes After four weeks of treatment, IL-1, IL-6, IL-17, ESR, CRP, and DAS28 in the treatment group were all lower than before treatment and those of the control group at corresponding time points with statistical difference (P < 0.01).
T13 1685-1851 Sentence denotes CONCLUSION: SYD combined MTX could play roles of improving inflammatory indices within 2 weeks, and inhibiting the expression of IL-1, IL-6, and IL-17 within 4 weeks.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 391-411 HP_0001370 denotes rheumatoid arthritis
T2 402-411 HP_0001369 denotes arthritis

chenxin_473849_800_3

Id Subject Object Predicate Lexical cue
T10 1697-1700 CI denotes SYD
T11 307-319 CI denotes methotrexate
T12 391-411 DP denotes rheumatoid arthritis
T13 102-122 DP denotes rheumatoid arthritis
T14 413-415 DP denotes RA
T15 533-535 DP denotes RA
T17 46-49 CI denotes MTX
T4 321-324 CI denotes MTX
T5 910-913 CI denotes MTX
T6 964-967 CI denotes MTX
T7 1710-1713 CI denotes MTX
T9 892-895 CI denotes SYD
T18 11-36 CI denotes Sanhuang Yilong Decoction
T19 261-286 CI denotes Sanhuang Yilong Decoction
T20 288-291 CI denotes SYD
T21 206-223 CI denotes bitter-cold herbs
T22 869-886 CI denotes bitter-cold herbs

yangbin123xm_800_3

Id Subject Object Predicate Lexical cue
T1 102-122 DP denotes rheumatoid arthritis
T10 1710-1713 CI denotes MTX
T2 391-411 DP denotes rheumatoid arthritis
T3 413-415 DP denotes RA
T4 533-535 DP denotes RA
T5 46-49 CI denotes MTX
T6 321-324 CI denotes MTX
T7 307-319 CI denotes methotrexate
T8 910-913 CI denotes MTX
T9 964-967 CI denotes MTX
T11 11-36 CI denotes Sanhuang Yilong Decoction
T12 261-286 CI denotes Sanhuang Yilong Decoction
T13 288-291 CI denotes SYD
T14 892-895 CI denotes SYD
T15 1697-1700 CI denotes SYD
T16 206-223 CI denotes bitter-cold herbs
T17 869-886 CI denotes bitter-cold herbs