> top > docs > PubMed:25572351 > annotations

PubMed:25572351 JSONTXT

Annnotations TAB JSON ListView MergeView

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 105-374 DRI_Challenge denotes To evaluate temporary exposure to hyperthermia for its impact on endothelial cell density of porcine corneas in organ culture medium containing dextran with regards to possible negative influences of high temperatures during the storage and transport of corneal grafts.
T2 375-530 DRI_Outcome denotes Four groups of central discs (diameter 8 mm) from the corneas of both eyes in 40 pigs were first organ-cultured (MEM with 6% dextran 500) for 24 h at 32°C.
T3 531-658 DRI_Background denotes Ten corneas were then exposed to 40°C in group 1, to 42°C in group 2, to 44°C in group 3, and to 50°C in group 4 for 12 h each.
T4 659-755 DRI_Approach denotes The paired corneal discs for all groups were not treated, stored at 32°C and served as controls.
T5 756-934 DRI_Outcome denotes After further organ culture of all corneas for 48 h at 32°C to allow regenerative processes, corneal endothelium was stained with Alizarin Red S and examined by light microscopy.
T6 935-1100 DRI_Approach denotes The endothelial cell densities were determined on three central images using a system for the automatic estimation of morphometric parameters of corneal endothelium.
T7 1101-1179 DRI_Background denotes Exposure for 12 h to 40°C as well as to 42°C induced no endothelial cell loss.
T8 1180-1504 DRI_Background denotes Statistical analysis showed no significant difference of the endothelial cell density between corneas exposed to 40°C and 42°C and the control corneas (40°C treatment: 4736 ± 426 cells/mm(2) and control: 4762 ± 344 cells/mm(2), p = 0.74; 42°C treatment: 4240 ± 363 cells/mm(2) and control: 4176 ± 448 cells/mm(2), p = 0.40).
T9 1505-1584 DRI_Background denotes Exposure to 44°C and 50°C lead to total necrosis of the endothelial cell layer.
T10 1585-1758 DRI_Background denotes Exposure of organ cultured porcine corneas in dextran containing medium up to 42°C for 12 h does not compromise the endothelial cell density in a clinically relevant manner.
T11 1759-1941 DRI_Outcome denotes Temperatures above 42°C, as it might be the case during transports from the cornea bank to the ophthalmic surgeon, must be strictly avoided as they damage the endothelial cell layer.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 453-455 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T2 517-521 CVCL_8262|Cancer_cell_line|Homo sapiens denotes 24 h
T3 528-529 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T4 531-534 CVCL_E063|Cancer_cell_line|Homo sapiens denotes Ten
T5 564-566 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T6 567-568 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T7 584-586 CVCL_2561|Transformed_cell_line|Homo sapiens denotes 42
T8 587-588 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T9 598-606 CVCL_ZT64|Transformed_cell_line|Homo sapiens denotes 2, to 44
T10 598-603 CVCL_R880|Spontaneously_immortalized_cell_line|Oreochromis mossambicus x Oreochromis niloticus denotes 2, to
T11 607-608 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T12 618-627 CVCL_B528|Embryonic_stem_cell|Homo sapiens denotes 3, and to
T13 628-630 CVCL_ZC06|Finite_cell_line|Homo sapiens denotes 50
T14 631-632 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T15 730-731 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T16 803-807 CVCL_J272|Hybridoma|Mus musculus denotes 48 h
T17 803-805 CVCL_J728|Hybridoma|Mus musculus denotes 48
T18 814-815 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T19 1012-1013 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T20 1122-1124 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T21 1125-1126 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T22 1141-1143 CVCL_2561|Transformed_cell_line|Homo sapiens denotes 42
T23 1144-1145 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T24 1293-1295 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T25 1296-1304 CVCL_4782|Cancer_cell_line|Homo sapiens denotes C and 42
T26 1296-1304 CVCL_WI17|Cancer_cell_line|Homo sapiens denotes C and 42
T27 1296-1297 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T28 1302-1304 CVCL_2561|Transformed_cell_line|Homo sapiens denotes 42
T29 1305-1306 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T30 1332-1334 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T31 1335-1336 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T32 1355-1358 CVCL_XC73|Hybridoma|Mus musculus denotes 426
T33 1365-1370 CVCL_B428|Cancer_cell_line|Mus musculus denotes mm(2)
T34 1365-1370 CVCL_VG91|Spontaneously_immortalized_cell_line|Mus musculus denotes mm(2)
T35 1365-1370 CVCL_WZ33|Cancer_cell_line|Homo sapiens denotes mm(2)
T36 1401-1406 CVCL_B428|Cancer_cell_line|Mus musculus denotes mm(2)
T37 1401-1406 CVCL_VG91|Spontaneously_immortalized_cell_line|Mus musculus denotes mm(2)
T38 1401-1406 CVCL_WZ33|Cancer_cell_line|Homo sapiens denotes mm(2)
T39 1418-1420 CVCL_2561|Transformed_cell_line|Homo sapiens denotes 42
T40 1421-1422 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T41 1451-1456 CVCL_B428|Cancer_cell_line|Mus musculus denotes mm(2)
T42 1451-1456 CVCL_VG91|Spontaneously_immortalized_cell_line|Mus musculus denotes mm(2)
T43 1451-1456 CVCL_WZ33|Cancer_cell_line|Homo sapiens denotes mm(2)
T44 1487-1492 CVCL_B428|Cancer_cell_line|Mus musculus denotes mm(2)
T45 1487-1492 CVCL_VG91|Spontaneously_immortalized_cell_line|Mus musculus denotes mm(2)
T46 1487-1492 CVCL_WZ33|Cancer_cell_line|Homo sapiens denotes mm(2)
T47 1520-1528 CVCL_0191|Transformed_cell_line|Mus musculus denotes C and 50
T48 1520-1521 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T49 1526-1528 CVCL_ZC06|Finite_cell_line|Homo sapiens denotes 50
T50 1529-1530 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T51 1663-1665 CVCL_2561|Transformed_cell_line|Homo sapiens denotes 42
T52 1666-1674 CVCL_0188|Spontaneously_immortalized_cell_line|Mus musculus denotes C for 12
T53 1666-1674 CVCL_W342|Cancer_cell_line|Homo sapiens denotes C for 12
T54 1666-1667 CVCL_S361|Finite_cell_line|Mus musculus denotes C
T55 1729-1730 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T56 1778-1780 CVCL_2561|Transformed_cell_line|Homo sapiens denotes 42
T57 1781-1782 CVCL_S361|Finite_cell_line|Mus musculus denotes C

GoldHamster

Id Subject Object Predicate Lexical cue
T1 0-6 PR:Q5GFD9 denotes Impact
T2 0-6 PR:O55091 denotes Impact
T3 20-32 D005334 denotes hyperthermia
T4 20-32 D005334 denotes hyperthermia
T5 36-60 CL:0000132 denotes corneal endothelial cell
T7 77-82 UBERON:0000062 denotes organ
T8 77-82 UBERON:0003103 denotes organ
T9 139-151 D005334 denotes hyperthermia
T10 139-151 D005334 denotes hyperthermia
T11 160-166 PR:Q54JW9 denotes impact
T12 160-166 PR:Q642J4 denotes impact
T13 170-186 CL:0000115 denotes endothelial cell
T14 206-213 UBERON:0000964 denotes corneas
T15 217-222 UBERON:0000062 denotes organ
T16 217-222 UBERON:0003103 denotes organ
T17 249-256 CHEBI:52071 denotes dextran
T18 249-256 D003911 denotes dextran
T19 249-256 D003911 denotes dextran
T20 334-341 GO:0051235 denotes storage
T21 346-355 GO:0006810 denotes transport
T22 429-436 UBERON:0000964 denotes corneas
T23 456-460 PR:Q9W3Y4 denotes pigs
T26 456-460 PR:Q6PD26 denotes pigs
T27 456-460 PR:Q5XI31 denotes pigs
T28 456-460 PR:Q96S52 denotes pigs
T29 456-460 PR:000012706 denotes pigs
T24 456-460 D013552 denotes pigs
T25 456-460 9823 denotes pigs
T30 472-477 UBERON:0000062 denotes organ
T31 472-477 UBERON:0003103 denotes organ
T32 500-507 CHEBI:52071 denotes dextran
T33 500-507 D003911 denotes dextran
T34 500-507 D003911 denotes dextran
T35 517-521 CVCL_8262 denotes 24 h
T36 535-542 UBERON:0000964 denotes corneas
T38 770-775 UBERON:0000062 denotes organ
T39 770-775 UBERON:0003103 denotes organ
T40 791-798 UBERON:0000964 denotes corneas
T41 838-847 UBERON:0004529 denotes processes
T42 849-868 UBERON:0001985 denotes corneal endothelium
T52 886-900 CHEBI:40863 denotes Alizarin Red S
T53 886-900 C004468 denotes Alizarin Red S
T54 886-900 C004468 denotes Alizarin Red S
T55 886-900 CHEBI:87358 denotes Alizarin Red S
T56 895-898 PR:Q9Z1M8 denotes Red
T57 895-900 D000080822 denotes Red S
T58 939-955 CL:0000115 denotes endothelial cell
T59 1080-1099 UBERON:0001985 denotes corneal endothelium
T62 1157-1173 CL:0000115 denotes endothelial cell
T63 1241-1257 CL:0000115 denotes endothelial cell
T64 1274-1281 UBERON:0000964 denotes corneas
T66 1323-1330 UBERON:0000964 denotes corneas
T79 1545-1553 GO:0019835 denotes necrosis
T80 1545-1553 GO:0008219 denotes necrosis
T83 1545-1553 GO:0008220 denotes necrosis
T84 1545-1553 GO:0001906 denotes necrosis
T85 1545-1553 GO:0070265 denotes necrosis
T81 1545-1553 D009336 denotes necrosis
T82 1545-1553 D009336 denotes necrosis
T86 1561-1577 CL:0000115 denotes endothelial cell
T87 1573-1583 UBERON:0000119 denotes cell layer
T90 1597-1602 UBERON:0000062 denotes organ
T91 1597-1602 UBERON:0003103 denotes organ
T92 1620-1627 UBERON:0000964 denotes corneas
T93 1631-1638 CHEBI:52071 denotes dextran
T94 1631-1638 D003911 denotes dextran
T95 1631-1638 D003911 denotes dextran
T96 1701-1717 CL:0000115 denotes endothelial cell
T97 1835-1841 UBERON:0000964 denotes cornea
T98 1854-1864 CHEBI:66981 denotes ophthalmic
T99 1918-1934 CL:0000115 denotes endothelial cell
T100 1930-1940 UBERON:0000119 denotes cell layer

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 139-151 HP_0001945 denotes hyperthermia